leucine has been researched along with Sensitivity and Specificity in 64 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.56) | 18.7374 |
1990's | 20 (31.25) | 18.2507 |
2000's | 28 (43.75) | 29.6817 |
2010's | 14 (21.88) | 24.3611 |
2020's | 1 (1.56) | 2.80 |
Authors | Studies |
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Banfield, L; Jakubowski, JS; Morton, RW; Nunes, EA; Phillips, SM; Teixeira, FJ; Vescio, V | 1 |
He, X; Wang, L; Wang, S; Yuan, Y; Zhang, Y; Zhong, J; Zhou, Y | 1 |
Irfanoglu, MO; Leopold, DA; Modi, P; Pierpaoli, C; Saleem, KS; Thomas, C; Ye, FQ | 1 |
Becker, S; Chevelkov, V; Demers, JP; Fasshuber, HK; Giller, K; Lange, A | 1 |
Chai, J; Chi, Y; Luo, H; Xu, C; Zhang, Q | 1 |
Fukada, R; Kugimiya, A | 1 |
Cui, J; Jiang, P; Liu, LN; Liu, RD; Qi, X; Wang, ZQ; Zhang, X; Zhang, ZF | 1 |
Bereczky, Z; Boda, Z; Gindele, R; Ilonczai, P; Kovács, B; Marján, E; Muszbek, L; Oláh, Z; Pfliegler, G; Selmeczi, A; Speker, M; Udvari, Á | 1 |
Alajmi, MF; Ali, I; Asnin, L; Hussain, A; Mukhtar, SD; Sahoo, DR; Suhail, M | 1 |
Chin, BB; Hawk, T; McDougald, D; Reiman, RE; Vaidyanathan, G; Weitzel, DH; Zalutsky, MR | 1 |
Chen, H; Cheng, H; Hyun, MH; Kim, JH; Koh, K; Lee, J | 1 |
Chan, CC; Chen, CY; Cho, NY; Chou, MC; Chung, HW; Huang, GS; Juan, CJ; Ko, CW; Lee, CS; Liu, HS; Tsai, SY; Wang, CY | 1 |
Horikoshi, M; Muto, S; Senda, M; Senda, T | 1 |
Gopinath, T; Veglia, G | 1 |
Hsieh, MM; Hsu, CY; Huang, SW; Tseng, WL; Wu, TH | 1 |
Cho, YJ; Heo, KS; Hyun, MH; Ryoo, JJ | 1 |
Arjomand, A; Chowdhury, SK; Gao, L; Hesk, D; Kasserra, C; Li, J; Song, Q | 1 |
Das, D; Das, S; Gupta, M; Laskar, S; Saha, R; Sahana, A | 1 |
Liang, MZ; Nan, F; Qin, YP; Wang, Z; Xiang, J; Yu, Q | 1 |
Deger, SM; Egbert, P; Ellis, CD; Hung, AM; Ikizler, TA; Sha, F; Siew, ED; Sundell, MB | 1 |
Gupta, JC; Mukherjee, KJ | 1 |
Conway, M; Cooper, AJ; Hutson, SM | 1 |
Matuszewski, BK; Schwartz, MS | 1 |
Bartlett, PN; Cass, AE; Halliwell, CM; Simon, E; Toh, CS | 1 |
Fernández, C; Hilty, C; Wider, G; Wüthrich, K | 1 |
PARKER, ED; SHIVE, W; SKINNER, CG | 1 |
Albright, R; Cobelli, C; Dietz, N; Joyner, M; Nair, KS; Toffolo, G | 1 |
Agbaria, RA; Fletcher, KA; Morris, K; Mwongela, S; Numan, A; Simuli, L; Tarus, J; Warner, IM | 1 |
Craik, CS; Dötsch, V; Hoch, JC; Kovacs, H; Nomura, AM; Shimada, I; Shimba, N; Stern, AS | 1 |
Baseren, M; Gokalp, S; Yazici, AR | 1 |
Ake, K; Ito, A; Kuramitsu, S; Masui, R; Okamura, TA; Tsunasawa, S; Ueyama, N; Yamamoto, H | 1 |
Alcaide-Hidalgo, JM; de Boer, AR; Irth, H; Kolkman, J; Krabbe, JG; Lingeman, H; Niessen, WM; van Emde Boas, CN | 1 |
Barrett, PH; Demant, T; Dinkel, RE; Parhofer, KG | 1 |
Alifrangis, M; Drakeley, C; Kulkarni, MA; Kweka, E; Lyimo, I; Magesa, S; Malima, R; Matowo, J; Mosha, FW; Peter, J; Rau, ME; Rowland, M; Salanti, A | 1 |
Agulnik, JS; Batist, G; Chong, G; Cohen, V; Jarry, J; Kreisman, H; Miller, WH; Small, D; Tejada, NA | 1 |
Feng, DR; He, YM; Liu, B; Wang, HB; Wang, JF; Zhang, DQ | 1 |
Chen, Y; Fan, G; Lin, M; Wang, C; Wu, Y; Zhao, W | 1 |
Cho, SH; Lee, CR; Peterkofsky, A; Seok, YJ; Yoon, MJ | 1 |
Bolbach, G; Eliash, R; Lahav, M; Rubinstein, I; Weissbuch, I | 1 |
Traaseth, NJ; Veglia, G; Verardi, R | 1 |
Chace, DH; Hillman, SL; Kahler, SG; Millington, DS; Naylor, EW; Roe, CR | 1 |
Arnoldi, L; Galati, G; Galli Kienle, M; Magni, F | 1 |
Barrio, JR; Keen, RE; Nissenson, CH | 1 |
Alemany, M; Fernández-López, JA; Latres, E; Remesar, X | 1 |
Adam, BW; Chace, DH; Hillman, SL; Kahler, SG; Levy, HL; Millington, DS | 1 |
Pronce, T; Tilquin, B | 1 |
Baba, S; Hasegawa, H; Nakamura, A; Shinohara, Y | 1 |
Auriola, S; Hämäläinen, KM; Ranta, VP; Urtti, A | 1 |
Johnson, HA | 1 |
Baldwin, RL; Calvert, CC; Johnson, HA | 1 |
Brenner, M; DeGracia, DJ; Dever, TE; Frerichs, KU; Hallenbeck, JM; Krause, GS; Marrone, L; Smith, CB | 1 |
Baldwin, RL; Calvert, CC; France, J; Johnson, HA | 1 |
Garlick, PJ; McNurlan, MA; Patlak, CS | 1 |
Boujet, C; Décorps, M; Estève, F; Grand, S; Hoffmann, D; Le Bas, JF; Passaro, G; Rémy, C; Rubin, C; Segebarth, C; Ziegler, A | 1 |
Hasegawa, H; Hashimoto, T; Matsukawa, T; Shinohara, Y | 1 |
Andrade, MA; Bork, P; Gibson, TJ; Ponting, CP | 1 |
Bastian, S; Egbring, R; Gempeler, M; Gempeler-Messina, P; Kohler, H; Kolde, H; Lenz, W; Meili, E; Moessmer, G; Poetzsch, B; Rudin, K; Wilmer, M | 1 |
Sansom, MS; Smith, GR | 1 |
Galarneau, A; Michnick, SW; Primeau, M; Trudeau, LE | 1 |
Davies, P; Jani, JP; Lazo, JS; Mistry, JS; Morris, G; Sebti, SM | 1 |
Cohen, LA; Creveling, CR; Kirk, KL; McNeal, ET; Padgett, WL | 1 |
Andert, S; Holzinger, C; Horvart, R; Kink, F; Laczkovics, A; Laufer, G; Seitelberger, R; Wolner, E; Zuckermann, A | 1 |
Admon, A; Hu, YF; Lüscher, B; Mermod, N; Tjian, R | 1 |
Krantz, DE; Zipursky, SL | 1 |
2 review(s) available for leucine and Sensitivity and Specificity
Article | Year |
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Supplementation with the Leucine Metabolite β-hydroxy-β-methylbutyrate (HMB) does not Improve Resistance Exercise-Induced Changes in Body Composition or Strength in Young Subjects: A Systematic Review and Meta-Analysis.
Topics: Adolescent; Adult; Body Composition; Body Mass Index; Databases, Factual; Dietary Supplements; Female; Humans; Leucine; Male; Muscle Strength; Muscle, Skeletal; Randomized Controlled Trials as Topic; Resistance Training; Sensitivity and Specificity; Valerates; Young Adult | 2020 |
Adaptation of protein metabolism in relation to limits to high dietary protein intake.
Topics: Adaptation, Physiological; Adult; Amino Acids; Body Composition; Body Constitution; Dietary Proteins; Energy Intake; Energy Metabolism; Humans; Leucine; Nitrogen; Nutrition Assessment; Oxidation-Reduction; Proteins; Radioisotopes; Sensitivity and Specificity | 1999 |
62 other study(ies) available for leucine and Sensitivity and Specificity
Article | Year |
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Serum metabolomics differentiating pancreatic cancer from new-onset diabetes.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Biomarkers, Tumor; Body Mass Index; CA-19-9 Antigen; Carcinoma, Pancreatic Ductal; Chromatography, Liquid; Diabetes Mellitus, Type 2; Diagnosis, Differential; Early Detection of Cancer; Feasibility Studies; Female; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Principal Component Analysis; Sensitivity and Specificity; Serologic Tests; Valine | 2017 |
Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited.
Topics: Algorithms; Animals; Axonal Transport; Axons; Body Water; Connectome; Contrast Media; Diffusion; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Gadolinium DTPA; Leucine; Macaca mulatta; Male; Models, Neurological; Motor Cortex; Occipital Lobe; Proline; Research Design; ROC Curve; Sensitivity and Specificity; Tritium; White Matter | 2014 |
Specific 13C labeling of leucine, valine and isoleucine methyl groups for unambiguous detection of long-range restraints in protein solid-state NMR studies.
Topics: Carbon Isotopes; Isoleucine; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Methylation; Peptide Mapping; Proteins; Protons; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Valine | 2015 |
Apelin inhibits the activation of the nucleotide-binding domain and the leucine-rich, repeat-containing family, pyrin-containing 3 (NLRP3) inflammasome and ameliorates insulin resistance in severely burned rats.
Topics: Analysis of Variance; Animals; Apelin; Binding Sites; Burns; Carrier Proteins; Cytokines; Cytoskeletal Proteins; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucose Tolerance Test; Inflammasomes; Injury Severity Score; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Leucine; Male; NG-Nitroarginine Methyl Ester; NLR Family, Pyrin Domain-Containing 3 Protein; Pyrin; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate | 2015 |
Chemiluminescence Detection of Serine, Proline, Glycine, Asparagine, Leucine, and Histidine by Using Corresponding Aminoacyl-tRNA Synthetases as Recognition Elements.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Biological Assay; Buffers; Glycine; Histidine; Humans; Leucine; Luminescence; Luminescent Measurements; Luminol; Proline; Sensitivity and Specificity; Serine; Solutions; Water | 2015 |
Characterization of Spirometra erinaceieuropaei Plerocercoid Cysteine Protease and Potential Application for Serodiagnosis of Sparganosis.
Topics: Animals; Blotting, Western; Cloning, Molecular; Cysteine Proteases; Enzyme-Linked Immunosorbent Assay; Hydrogen-Ion Concentration; Leucine; Mice; Neglected Diseases; Recombinant Proteins; Sensitivity and Specificity; Serologic Tests; Sparganosis; Sparganum; Spirometra; Temperature | 2015 |
Founder effect is responsible for the p.Leu131Phe heparin-binding-site antithrombin mutation common in Hungary: phenotype analysis in a large cohort.
Topics: Adolescent; Adult; Aged; Antithrombins; Arteries; Binding Sites; Child; Child, Preschool; Cohort Studies; Factor Xa; Female; Founder Effect; Genetic Association Studies; Heparin; Heterozygote; Humans; Hungary; Leucine; Microsatellite Repeats; Middle Aged; Mutation; Phenotype; Phenylalanine; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Cardiovascular; Sensitivity and Specificity; Thrombosis; Young Adult | 2016 |
Chiral HPLC Separation and Modeling of Four Stereomers of DL-Leucine-DL-Tryptophan Dipeptide on Amylose Chiral Column.
Topics: Amylose; Chromatography, High Pressure Liquid; Dipeptides; Leucine; Limit of Detection; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Tryptophan | 2016 |
Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Leucine; Mice; Mice, Inbred BALB C; Molecular Structure; Positron Emission Tomography Computed Tomography; Radiometry; Radiopharmaceuticals; Sensitivity and Specificity; Tissue Distribution | 2017 |
Surface plasmon resonance spectroscopic chiral discrimination using self-assembled leucine derivative monolayer.
Topics: Absorption; Leucine; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Surface Plasmon Resonance | 2008 |
Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy.
Topics: Adult; Alanine; Amino Acids; Biomarkers; Brain Abscess; Female; Humans; Image Processing, Computer-Assisted; Isoleucine; Lactic Acid; Leucine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Sensitivity and Specificity; Valine; Young Adult | 2008 |
Effect of leucine-to-methionine substitutions on the diffraction quality of histone chaperone SET/TAF-Ibeta/INHAT crystals.
Topics: Amino Acid Substitution; Chromosomal Proteins, Non-Histone; Crystallization; Crystallography, X-Ray; DNA-Binding Proteins; Genetic Variation; Histone Chaperones; Histones; Humans; Leucine; Methionine; Molecular Chaperones; Sensitivity and Specificity; Transcription Factors | 2008 |
Sensitivity enhancement in static solid-state NMR experiments via single- and multiple-quantum dipolar coherences.
Topics: Crystallization; Leucine; Nuclear Magnetic Resonance, Biomolecular; Sensitivity and Specificity | 2009 |
Highly sensitive detection of chiral amino acids by CE based on on-line stacking techniques.
Topics: Amino Acids; Chromatography, Micellar Electrokinetic Capillary; Humans; Leucine; Linear Models; Sensitivity and Specificity; Stereoisomerism | 2009 |
Determination of optical purity of 3,5-dimethoxybenzoyl-leucine diethylamide by chiral chromatography and 1H and 13C NMR spectroscopy.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Chromatography, High Pressure Liquid; Dinitrobenzenes; Hydrogen; Indicators and Reagents; Kinetics; Leucine; Magnetic Resonance Spectroscopy; Molecular Structure; Sensitivity and Specificity; Stereoisomerism | 2011 |
Precision and accuracy in the quantitative analysis of biological samples by accelerator mass spectrometry: application in microdose absolute bioavailability studies.
Topics: Administration, Oral; Adult; Antiviral Agents; Calibration; Chromatography, Liquid; Cyclopropanes; Dipeptides; Humans; Injections, Intravenous; Leucine; Male; Middle Aged; Proline; Reproducibility of Results; Sensitivity and Specificity; Sulfones; Tandem Mass Spectrometry; Urea; Young Adult | 2011 |
Identification and interaction of amino acids with leucine-anthracene reagent by TLC and spectrophotometry: experimental and theoretical studies.
Topics: Amino Acids; Anthracenes; Chromatography, Thin Layer; Leucine; Methanol; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Plant Proteins; Protein Binding; Sensitivity and Specificity; Solutions | 2011 |
[Determination of ubenimex in human plasma by HPLC-MS/MS].
Topics: Adjuvants, Immunologic; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Humans; Leucine; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |
Insulin resistance and protein metabolism in chronic hemodialysis patients.
Topics: Adult; Aged; Amino Acids; Black or African American; Blood Glucose; Body Composition; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Leucine; Male; Middle Aged; Proteins; Renal Dialysis; Sarcopenia; Sensitivity and Specificity | 2013 |
Stability studies of recombinant Saccharomyces cerevisiae in the presence of varying selection pressure.
Topics: beta-Galactosidase; Bioreactors; Cell Count; Cells, Cultured; Computer Simulation; Culture Media; Gene Expression Regulation, Fungal; Leucine; Models, Biological; Plasmids; Recombinant Proteins; Recombination, Genetic; Saccharomyces cerevisiae; Selection, Genetic; Sensitivity and Specificity; Sucrose | 2002 |
A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases.
Topics: Ammonia; Animals; Cytosol; Glutamate Dehydrogenase; Humans; Leucine; Male; Mitochondria; Organ Specificity; Radiochemistry; Rats; Rats, Inbred F344; Recombinant Proteins; Sensitivity and Specificity; Spectrophotometry; Substrate Specificity; Transaminases | 2002 |
Determination of a peptide-doxorubicin, prostate-specific antigen activated prodrug, and its active metabolites in human plasma using high-performance liquid chromatography with fluorescence detection. Stabilization of the peptide prodrug with EDTA.
Topics: Chromatography, High Pressure Liquid; Doxorubicin; Edetic Acid; Leucine; Prodrugs; Prostate-Specific Antigen; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2002 |
A method for the determination of enzyme mass loading on an electrode surface through radioisotope labelling.
Topics: Aniline Compounds; Biosensing Techniques; Catalysis; Coated Materials, Biocompatible; Electrochemistry; Enzyme Activation; Enzymes, Immobilized; Equipment Design; Isotope Labeling; L-Lactate Dehydrogenase; Leucine; Microscopy, Electron, Scanning; Recombinant Proteins; Scintillation Counting; Sensitivity and Specificity | 2002 |
Side chain NMR assignments in the membrane protein OmpX reconstituted in DHPC micelles.
Topics: Amino Acids; Bacterial Outer Membrane Proteins; Cold Temperature; Escherichia coli Proteins; Hydrolases; Isoleucine; Isotopes; Leucine; Membranes, Artificial; Micelles; Nuclear Magnetic Resonance, Biomolecular; Phospholipid Ethers; Sensitivity and Specificity; Valine | 2002 |
Biological specificities of 4,5-dehydro analogues of isoleucine and alloisoleucine.
Topics: Isoleucine; Leucine; Organic Chemicals; Sensitivity and Specificity | 1961 |
Model to assess muscle protein turnover: domain of validity using amino acyl-tRNA vs. surrogate measures of precursor pool.
Topics: Adult; Arteries; Biological Transport; Carbon Isotopes; False Negative Reactions; False Positive Reactions; Humans; Keto Acids; Kinetics; Leucine; Mathematics; Models, Biological; Muscle Proteins; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; RNA, Transfer, Amino Acyl; Sensitivity and Specificity; Veins | 2003 |
Influence of the polydispersity of polymeric surfactants on the enantioselectivity of chiral compounds in micellar electrokinetic chromatography.
Topics: Chromatography, Micellar Electrokinetic Capillary; Leucine; Magnetic Resonance Spectroscopy; Micelles; Molecular Structure; Molecular Weight; Particle Size; Polymers; Sensitivity and Specificity; Spectrometry, Fluorescence; Stereoisomerism; Surface Properties; Surface-Active Agents; Time Factors; Ultracentrifugation | 2004 |
Optimization of 13C direct detection NMR methods.
Topics: Carbon Isotopes; Leucine; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Sodium Chloride; Solutions | 2004 |
The in vitro performance of laser fluorescence and caries-detector dye for detecting residual carious dentin during tooth preparation.
Topics: Coloring Agents; Dental Caries; Dental Caries Activity Tests; Dental Cavity Preparation; Dentin; Fluorescence; Glutamic Acid; Humans; Lasers; Leucine; Lysine; Microscopy, Polarization; Molar; Observer Variation; Reproducibility of Results; Sensitivity and Specificity | 2005 |
Distinction of Leu and Ile Using a Ruthenium(II) complex by MALDI-LIFT-TOF/TOF-MS analysis.
Topics: Isoleucine; Leucine; Molecular Structure; Organometallic Compounds; Ruthenium; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
High-temperature liquid chromatography coupled on-line to a continuous-flow biochemical screening assay with electrospray ionization mass spectrometric detection.
Topics: Cathepsin B; Chromatography, Liquid; Dipeptides; Drug Stability; Hot Temperature; Leucine; Leupeptins; Online Systems; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tea | 2005 |
In-vivo metabolism of VLDL-apolipoprotein-B, -CIII and -E in normolipidemic subjects.
Topics: Adult; Apolipoprotein C-III; Apolipoproteins B; Apolipoproteins C; Apolipoproteins E; Area Under Curve; Cholesterol, VLDL; Chromatography, High Pressure Liquid; Humans; Leucine; Lipoproteins; Lipoproteins, VLDL; Male; Sensitivity and Specificity | 2006 |
Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method.
Topics: Animals; Anopheles; Enzyme-Linked Immunosorbent Assay; Female; Insecticide Resistance; Leucine; Mutation; Oligonucleotide Probes; Phenylalanine; Polymerase Chain Reaction; Pyrethrins; Sensitivity and Specificity; Tanzania | 2006 |
Evaluation of denaturing high-performance liquid chromatography as a rapid detection method for identification of epidermal growth factor receptor mutations in nonsmall-cell lung cancer.
Topics: Arginine; Carcinoma, Non-Small-Cell Lung; Chromatography, High Pressure Liquid; DNA Mutational Analysis; ErbB Receptors; Humans; Leucine; Lung Neoplasms; Mutation; Nucleic Acid Denaturation; Sensitivity and Specificity | 2006 |
Carrot antifreeze protein does not exhibit the polygalacturonase-inhibiting activity of PGIP family.
Topics: Alternaria; Amino Acid Motifs; Amino Acid Sequence; Antifreeze Proteins; Cloning, Molecular; Daucus carota; DNA, Complementary; Leucine; Models, Molecular; Molecular Sequence Data; Plant Proteins; Polygalacturonase; Protein Binding; Protein Conformation; Repetitive Sequences, Amino Acid; Sensitivity and Specificity; Sequence Alignment; Two-Hybrid System Techniques | 2006 |
Development of a liquid chromatography/tandem mass spectrometry assay for the determination of bestatin in rat plasma and its application to a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Leucine; Male; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2007 |
Escherichia coli enzyme IIANtr regulates the K+ transporter TrkA.
Topics: Biological Transport; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Leucine; Ligands; Models, Biological; Mutation; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Potassium; Protein Binding; Receptor, trkA; Sensitivity and Specificity; Surface Plasmon Resonance; Time Factors | 2007 |
Racemic beta sheets in biochirogenesis.
Topics: Amines; Hydrogen Bonding; Kinetics; Leucine; Oligopeptides; Protein Structure, Secondary; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Valine | 2007 |
Asymmetric methyl group labeling as a probe of membrane protein homo-oligomers by NMR spectroscopy.
Topics: Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Oligonucleotide Probes; Protein Conformation; Protein Structure, Secondary; Reference Standards; Sensitivity and Specificity | 2008 |
Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry.
Topics: False Positive Reactions; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Mass Spectrometry; Neonatal Screening; Paper; Phenylalanine; Reference Values; Sensitivity and Specificity; Valine | 1995 |
Simultaneous determination of plasma levels of alpha-ketoisocaproic acid and leucine and evaluation of alpha-[1-13C]ketoisocaproic acid and [1-13C]leucine enrichment by gas chromatography-mass spectrometry.
Topics: Carbon Isotopes; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Keto Acids; Leucine; Sensitivity and Specificity | 1994 |
Analysis of femtomole concentrations of alpha-ketoisocaproic acid in brain tissue by precolumn fluorescence derivatization with 4,5-dimethoxy-1,2-diaminobenzene.
Topics: Animals; Brain Chemistry; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Fluorescent Dyes; Fluorometry; Keto Acids; Leucine; Male; Microchemistry; Phenylenediamines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Swine | 1993 |
A radio-enzymatic method for the estimation of L-leucine-specific radioactivity.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Carbon Radioisotopes; Leucine; Radiometry; Rats; Rats, Wistar; RNA, Transfer, Leu; Sensitivity and Specificity | 1993 |
Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry.
Topics: Blood Specimen Collection; Chromatography, High Pressure Liquid; Homocystinuria; Humans; Infant, Newborn; Isoleucine; Leucine; Mass Spectrometry; Metabolism, Inborn Errors; Methionine; Neonatal Screening; Paper; Sensitivity and Specificity | 1996 |
Trace analysis in chiral separation of selected amino enantiomers.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Fluorometry; Leucine; Perchlorates; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Threonine | 1996 |
Determination of [D-Ala2,D-Leu5]enkephalin and the metabolites containing C-terminal D-leucine by high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Enkephalin, Leucine-2-Alanine; Leucine; Male; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity | 1997 |
Gradient high-performance liquid chromatographic analysis of enkephalin peptides, their metabolites, and enzyme inhibitors using combined ultraviolet and electrochemical detection II. Application to ocular permeability studies in vitro.
Topics: Aminopeptidases; Animals; Bicarbonates; Calibration; Chromatography, High Pressure Liquid; Colorimetry; Conjunctiva; Cornea; Dipeptides; Drug Combinations; Electrochemistry; Enkephalin, Methionine; Glutathione; In Vitro Techniques; Leucine; Neprilysin; Permeability; Protease Inhibitors; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Solutions; Spectrophotometry, Ultraviolet | 1998 |
Modeling protein turnover: a module for teaching modeling.
Topics: Animals; Computer Simulation; Computer-Assisted Instruction; Leucine; Linear Models; Mice; Models, Biological; Numerical Analysis, Computer-Assisted; Protein Biosynthesis; Proteins; Radioactive Tracers; Reference Values; RNA, Transfer; Sensitivity and Specificity | 1998 |
Designing a radioisotope experiment using a dynamic, mechanistic model of protein turnover.
Topics: Animals; Leucine; Mice; Models, Biological; Protein Biosynthesis; Proteins; Radioactive Tracers; Rats; RNA, Transfer, Leu; Sensitivity and Specificity | 1998 |
Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation.
Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Brain; Carbon Radioisotopes; Eukaryotic Initiation Factor-2; Hibernation; Leucine; Nerve Tissue Proteins; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Protein Biosynthesis; Ribosomes; RNA, Messenger; Sciuridae; Sensitivity and Specificity; Transcription, Genetic | 1998 |
Recycling, channeling and heterogeneous protein turnover estimation using a model of whole-body protein turnover based on leucine kinetics in rodents.
Topics: Animals; Carbon Radioisotopes; False Negative Reactions; Kinetics; Leucine; Mice; Models, Biological; Protein Biosynthesis; Proteins; RNA, Transfer, Leu; Sensitivity and Specificity | 1999 |
Necrotic tumor versus brain abscess: importance of amino acids detected at 1H MR spectroscopy--initial results.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Brain; Brain Abscess; Brain Neoplasms; Diagnosis, Differential; Female; Humans; Isoleucine; Leucine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Necrosis; Phantoms, Imaging; Sensitivity and Specificity; Valine | 1999 |
Simultaneous determination of the enantiomers of leucine and [2H7]leucine in plasma by capillary gas chromatography-mass spectrometry.
Topics: Animals; Calibration; Gas Chromatography-Mass Spectrometry; Leucine; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Tritium | 1999 |
Homology-based method for identification of protein repeats using statistical significance estimates.
Topics: Algorithms; Alkyl and Aryl Transferases; Amino Acid Motifs; Animals; Ankyrins; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Cycle Proteins; Computational Biology; Databases, Factual; DNA-Binding Proteins; Farnesyltranstransferase; Genome; Guanine Nucleotide Exchange Factors; Heat-Shock Proteins; Helminth Proteins; HSP40 Heat-Shock Proteins; Humans; Leucine; Models, Molecular; Molecular Chaperones; Nuclear Proteins; Phylogeny; Protein Structure, Secondary; Proteins; Repetitive Sequences, Amino Acid; Saccharomyces cerevisiae; Sensitivity and Specificity; Sequence Alignment; Sequence Homology, Amino Acid | 2000 |
Evaluation of a sensitive colorimetric FXIII incorporation assay. Effects of FXIII Val34Leu, plasma fibrinogen concentration and congenital FXIII deficiency.
Topics: Amines; Amino Acid Substitution; Ammonia; Chromogenic Compounds; Clinical Chemistry Tests; Enzyme-Linked Immunosorbent Assay; Factor XIII; Factor XIII Deficiency; Fibrinogen; Humans; Kinetics; Leucine; Point Mutation; Sensitivity and Specificity; Valine | 2001 |
Free energy of a potassium ion in a model of the channel formed by an amphipathic leucine-serine peptide.
Topics: Biomimetic Materials; Computer Simulation; Electric Conductivity; Electrochemistry; Ions; Leucine; Models, Chemical; Models, Molecular; Potassium; Potassium Channels; Protein Conformation; Sensitivity and Specificity; Serine; Surface-Active Agents; Thermodynamics | 2002 |
Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; bcl-Associated Death Protein; beta-Lactamases; Carrier Proteins; Cattle; Cell Line; Cephalosporins; DNA-Binding Proteins; Humans; Immunophilins; Kidney; Leucine; Microscopy, Fluorescence; Peptide Fragments; Peptide Library; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Protein Folding; Protein Interaction Mapping; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Reproducibility of Results; Saccharomyces cerevisiae Proteins; Sensitivity and Specificity; Smad3 Protein; TOR Serine-Threonine Kinases; Trans-Activators | 2002 |
In vivo circumvention of human colon carcinoma resistance to bleomycin.
Topics: Animals; Bleomycin; Colonic Neoplasms; Cysteine Proteinase Inhibitors; Drug Interactions; Drug Resistance; Female; Humans; Leucine; Lung; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Pulmonary Fibrosis; Sensitivity and Specificity; Tissue Distribution; Transplantation, Heterologous | 1992 |
Incorporation of 2-fluorohistidine in murine protein in vivo.
Topics: Animals; Body Weight; Brain; Carbon Radioisotopes; Cycloheximide; Dose-Response Relationship, Drug; Histidine; Kidney; Leucine; Liver; Male; Mice; Mice, Inbred BALB C; Proteins; Sensitivity and Specificity; Solubility; Tissue Distribution; Tritium | 1992 |
Monitoring of mononuclear cell subsets isolated from the coronary sinus and the right atrium in patients after heart allograft transplantation.
Topics: Antigens, CD; Biopsy; Blood; Coronary Vessels; Endocardium; Graft Rejection; Heart Atria; Heart Transplantation; Humans; Leucine; Leukocyte Count; Lymphocyte Subsets; Sensitivity and Specificity | 1991 |
Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.
Topics: Amino Acid Sequence; Base Sequence; Biopolymers; Cross-Linking Reagents; DNA; DNA-Binding Proteins; Genetic Vectors; Glutaral; HeLa Cells; Humans; Leucine; Molecular Sequence Data; Protein Biosynthesis; Sensitivity and Specificity; Transcription Factors; Transcription, Genetic; Vaccinia virus | 1990 |
Drosophila chaoptin, a member of the leucine-rich repeat family, is a photoreceptor cell-specific adhesion molecule.
Topics: Animals; Cell Adhesion; Cell Aggregation; Cell Membrane; Cells, Cultured; DNA; Drosophila; Drosophila Proteins; Glycolipids; Leucine; Membrane Glycoproteins; Multigene Family; Photoreceptor Cells; Sensitivity and Specificity; Time Factors; Type C Phospholipases | 1990 |