leucine and Sensitivity and Specificity

leucine has been researched along with Sensitivity and Specificity in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.56)18.7374
1990's20 (31.25)18.2507
2000's28 (43.75)29.6817
2010's14 (21.88)24.3611
2020's1 (1.56)2.80

Authors

AuthorsStudies
Banfield, L; Jakubowski, JS; Morton, RW; Nunes, EA; Phillips, SM; Teixeira, FJ; Vescio, V1
He, X; Wang, L; Wang, S; Yuan, Y; Zhang, Y; Zhong, J; Zhou, Y1
Irfanoglu, MO; Leopold, DA; Modi, P; Pierpaoli, C; Saleem, KS; Thomas, C; Ye, FQ1
Becker, S; Chevelkov, V; Demers, JP; Fasshuber, HK; Giller, K; Lange, A1
Chai, J; Chi, Y; Luo, H; Xu, C; Zhang, Q1
Fukada, R; Kugimiya, A1
Cui, J; Jiang, P; Liu, LN; Liu, RD; Qi, X; Wang, ZQ; Zhang, X; Zhang, ZF1
Bereczky, Z; Boda, Z; Gindele, R; Ilonczai, P; Kovács, B; Marján, E; Muszbek, L; Oláh, Z; Pfliegler, G; Selmeczi, A; Speker, M; Udvari, Á1
Alajmi, MF; Ali, I; Asnin, L; Hussain, A; Mukhtar, SD; Sahoo, DR; Suhail, M1
Chin, BB; Hawk, T; McDougald, D; Reiman, RE; Vaidyanathan, G; Weitzel, DH; Zalutsky, MR1
Chen, H; Cheng, H; Hyun, MH; Kim, JH; Koh, K; Lee, J1
Chan, CC; Chen, CY; Cho, NY; Chou, MC; Chung, HW; Huang, GS; Juan, CJ; Ko, CW; Lee, CS; Liu, HS; Tsai, SY; Wang, CY1
Horikoshi, M; Muto, S; Senda, M; Senda, T1
Gopinath, T; Veglia, G1
Hsieh, MM; Hsu, CY; Huang, SW; Tseng, WL; Wu, TH1
Cho, YJ; Heo, KS; Hyun, MH; Ryoo, JJ1
Arjomand, A; Chowdhury, SK; Gao, L; Hesk, D; Kasserra, C; Li, J; Song, Q1
Das, D; Das, S; Gupta, M; Laskar, S; Saha, R; Sahana, A1
Liang, MZ; Nan, F; Qin, YP; Wang, Z; Xiang, J; Yu, Q1
Deger, SM; Egbert, P; Ellis, CD; Hung, AM; Ikizler, TA; Sha, F; Siew, ED; Sundell, MB1
Gupta, JC; Mukherjee, KJ1
Conway, M; Cooper, AJ; Hutson, SM1
Matuszewski, BK; Schwartz, MS1
Bartlett, PN; Cass, AE; Halliwell, CM; Simon, E; Toh, CS1
Fernández, C; Hilty, C; Wider, G; Wüthrich, K1
PARKER, ED; SHIVE, W; SKINNER, CG1
Albright, R; Cobelli, C; Dietz, N; Joyner, M; Nair, KS; Toffolo, G1
Agbaria, RA; Fletcher, KA; Morris, K; Mwongela, S; Numan, A; Simuli, L; Tarus, J; Warner, IM1
Craik, CS; Dötsch, V; Hoch, JC; Kovacs, H; Nomura, AM; Shimada, I; Shimba, N; Stern, AS1
Baseren, M; Gokalp, S; Yazici, AR1
Ake, K; Ito, A; Kuramitsu, S; Masui, R; Okamura, TA; Tsunasawa, S; Ueyama, N; Yamamoto, H1
Alcaide-Hidalgo, JM; de Boer, AR; Irth, H; Kolkman, J; Krabbe, JG; Lingeman, H; Niessen, WM; van Emde Boas, CN1
Barrett, PH; Demant, T; Dinkel, RE; Parhofer, KG1
Alifrangis, M; Drakeley, C; Kulkarni, MA; Kweka, E; Lyimo, I; Magesa, S; Malima, R; Matowo, J; Mosha, FW; Peter, J; Rau, ME; Rowland, M; Salanti, A1
Agulnik, JS; Batist, G; Chong, G; Cohen, V; Jarry, J; Kreisman, H; Miller, WH; Small, D; Tejada, NA1
Feng, DR; He, YM; Liu, B; Wang, HB; Wang, JF; Zhang, DQ1
Chen, Y; Fan, G; Lin, M; Wang, C; Wu, Y; Zhao, W1
Cho, SH; Lee, CR; Peterkofsky, A; Seok, YJ; Yoon, MJ1
Bolbach, G; Eliash, R; Lahav, M; Rubinstein, I; Weissbuch, I1
Traaseth, NJ; Veglia, G; Verardi, R1
Chace, DH; Hillman, SL; Kahler, SG; Millington, DS; Naylor, EW; Roe, CR1
Arnoldi, L; Galati, G; Galli Kienle, M; Magni, F1
Barrio, JR; Keen, RE; Nissenson, CH1
Alemany, M; Fernández-López, JA; Latres, E; Remesar, X1
Adam, BW; Chace, DH; Hillman, SL; Kahler, SG; Levy, HL; Millington, DS1
Pronce, T; Tilquin, B1
Baba, S; Hasegawa, H; Nakamura, A; Shinohara, Y1
Auriola, S; Hämäläinen, KM; Ranta, VP; Urtti, A1
Johnson, HA1
Baldwin, RL; Calvert, CC; Johnson, HA1
Brenner, M; DeGracia, DJ; Dever, TE; Frerichs, KU; Hallenbeck, JM; Krause, GS; Marrone, L; Smith, CB1
Baldwin, RL; Calvert, CC; France, J; Johnson, HA1
Garlick, PJ; McNurlan, MA; Patlak, CS1
Boujet, C; Décorps, M; Estève, F; Grand, S; Hoffmann, D; Le Bas, JF; Passaro, G; Rémy, C; Rubin, C; Segebarth, C; Ziegler, A1
Hasegawa, H; Hashimoto, T; Matsukawa, T; Shinohara, Y1
Andrade, MA; Bork, P; Gibson, TJ; Ponting, CP1
Bastian, S; Egbring, R; Gempeler, M; Gempeler-Messina, P; Kohler, H; Kolde, H; Lenz, W; Meili, E; Moessmer, G; Poetzsch, B; Rudin, K; Wilmer, M1
Sansom, MS; Smith, GR1
Galarneau, A; Michnick, SW; Primeau, M; Trudeau, LE1
Davies, P; Jani, JP; Lazo, JS; Mistry, JS; Morris, G; Sebti, SM1
Cohen, LA; Creveling, CR; Kirk, KL; McNeal, ET; Padgett, WL1
Andert, S; Holzinger, C; Horvart, R; Kink, F; Laczkovics, A; Laufer, G; Seitelberger, R; Wolner, E; Zuckermann, A1
Admon, A; Hu, YF; Lüscher, B; Mermod, N; Tjian, R1
Krantz, DE; Zipursky, SL1

Reviews

2 review(s) available for leucine and Sensitivity and Specificity

ArticleYear
Supplementation with the Leucine Metabolite β-hydroxy-β-methylbutyrate (HMB) does not Improve Resistance Exercise-Induced Changes in Body Composition or Strength in Young Subjects: A Systematic Review and Meta-Analysis.
    Nutrients, 2020, May-23, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Body Composition; Body Mass Index; Databases, Factual; Dietary Supplements; Female; Humans; Leucine; Male; Muscle Strength; Muscle, Skeletal; Randomized Controlled Trials as Topic; Resistance Training; Sensitivity and Specificity; Valerates; Young Adult

2020
Adaptation of protein metabolism in relation to limits to high dietary protein intake.
    European journal of clinical nutrition, 1999, Volume: 53 Suppl 1

    Topics: Adaptation, Physiological; Adult; Amino Acids; Body Composition; Body Constitution; Dietary Proteins; Energy Intake; Energy Metabolism; Humans; Leucine; Nitrogen; Nutrition Assessment; Oxidation-Reduction; Proteins; Radioisotopes; Sensitivity and Specificity

1999

Other Studies

62 other study(ies) available for leucine and Sensitivity and Specificity

ArticleYear
Serum metabolomics differentiating pancreatic cancer from new-onset diabetes.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Biomarkers, Tumor; Body Mass Index; CA-19-9 Antigen; Carcinoma, Pancreatic Ductal; Chromatography, Liquid; Diabetes Mellitus, Type 2; Diagnosis, Differential; Early Detection of Cancer; Feasibility Studies; Female; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Principal Component Analysis; Sensitivity and Specificity; Serologic Tests; Valine

2017
Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Nov-18, Volume: 111, Issue:46

    Topics: Algorithms; Animals; Axonal Transport; Axons; Body Water; Connectome; Contrast Media; Diffusion; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Gadolinium DTPA; Leucine; Macaca mulatta; Male; Models, Neurological; Motor Cortex; Occipital Lobe; Proline; Research Design; ROC Curve; Sensitivity and Specificity; Tritium; White Matter

2014
Specific 13C labeling of leucine, valine and isoleucine methyl groups for unambiguous detection of long-range restraints in protein solid-state NMR studies.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2015, Volume: 252

    Topics: Carbon Isotopes; Isoleucine; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Methylation; Peptide Mapping; Proteins; Protons; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Valine

2015
Apelin inhibits the activation of the nucleotide-binding domain and the leucine-rich, repeat-containing family, pyrin-containing 3 (NLRP3) inflammasome and ameliorates insulin resistance in severely burned rats.
    Surgery, 2015, Volume: 157, Issue:6

    Topics: Analysis of Variance; Animals; Apelin; Binding Sites; Burns; Carrier Proteins; Cytokines; Cytoskeletal Proteins; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucose Tolerance Test; Inflammasomes; Injury Severity Score; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Leucine; Male; NG-Nitroarginine Methyl Ester; NLR Family, Pyrin Domain-Containing 3 Protein; Pyrin; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate

2015
Chemiluminescence Detection of Serine, Proline, Glycine, Asparagine, Leucine, and Histidine by Using Corresponding Aminoacyl-tRNA Synthetases as Recognition Elements.
    Applied biochemistry and biotechnology, 2015, Volume: 176, Issue:4

    Topics: Amino Acyl-tRNA Synthetases; Asparagine; Biological Assay; Buffers; Glycine; Histidine; Humans; Leucine; Luminescence; Luminescent Measurements; Luminol; Proline; Sensitivity and Specificity; Serine; Solutions; Water

2015
Characterization of Spirometra erinaceieuropaei Plerocercoid Cysteine Protease and Potential Application for Serodiagnosis of Sparganosis.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:6

    Topics: Animals; Blotting, Western; Cloning, Molecular; Cysteine Proteases; Enzyme-Linked Immunosorbent Assay; Hydrogen-Ion Concentration; Leucine; Mice; Neglected Diseases; Recombinant Proteins; Sensitivity and Specificity; Serologic Tests; Sparganosis; Sparganum; Spirometra; Temperature

2015
Founder effect is responsible for the p.Leu131Phe heparin-binding-site antithrombin mutation common in Hungary: phenotype analysis in a large cohort.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Aged; Antithrombins; Arteries; Binding Sites; Child; Child, Preschool; Cohort Studies; Factor Xa; Female; Founder Effect; Genetic Association Studies; Heparin; Heterozygote; Humans; Hungary; Leucine; Microsatellite Repeats; Middle Aged; Mutation; Phenotype; Phenylalanine; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Cardiovascular; Sensitivity and Specificity; Thrombosis; Young Adult

2016
Chiral HPLC Separation and Modeling of Four Stereomers of DL-Leucine-DL-Tryptophan Dipeptide on Amylose Chiral Column.
    Chirality, 2016, Volume: 28, Issue:9

    Topics: Amylose; Chromatography, High Pressure Liquid; Dipeptides; Leucine; Limit of Detection; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Tryptophan

2016
Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine.
    Current radiopharmaceuticals, 2017, Volume: 10, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Leucine; Mice; Mice, Inbred BALB C; Molecular Structure; Positron Emission Tomography Computed Tomography; Radiometry; Radiopharmaceuticals; Sensitivity and Specificity; Tissue Distribution

2017
Surface plasmon resonance spectroscopic chiral discrimination using self-assembled leucine derivative monolayer.
    Talanta, 2008, Jun-30, Volume: 76, Issue:1

    Topics: Absorption; Leucine; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Surface Plasmon Resonance

2008
Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy.
    AJNR. American journal of neuroradiology, 2008, Volume: 29, Issue:9

    Topics: Adult; Alanine; Amino Acids; Biomarkers; Brain Abscess; Female; Humans; Image Processing, Computer-Assisted; Isoleucine; Lactic Acid; Leucine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Sensitivity and Specificity; Valine; Young Adult

2008
Effect of leucine-to-methionine substitutions on the diffraction quality of histone chaperone SET/TAF-Ibeta/INHAT crystals.
    Acta crystallographica. Section F, Structural biology and crystallization communications, 2008, Oct-01, Volume: 64, Issue:Pt 10

    Topics: Amino Acid Substitution; Chromosomal Proteins, Non-Histone; Crystallization; Crystallography, X-Ray; DNA-Binding Proteins; Genetic Variation; Histone Chaperones; Histones; Humans; Leucine; Methionine; Molecular Chaperones; Sensitivity and Specificity; Transcription Factors

2008
Sensitivity enhancement in static solid-state NMR experiments via single- and multiple-quantum dipolar coherences.
    Journal of the American Chemical Society, 2009, Apr-29, Volume: 131, Issue:16

    Topics: Crystallization; Leucine; Nuclear Magnetic Resonance, Biomolecular; Sensitivity and Specificity

2009
Highly sensitive detection of chiral amino acids by CE based on on-line stacking techniques.
    Electrophoresis, 2009, Volume: 30, Issue:14

    Topics: Amino Acids; Chromatography, Micellar Electrokinetic Capillary; Humans; Leucine; Linear Models; Sensitivity and Specificity; Stereoisomerism

2009
Determination of optical purity of 3,5-dimethoxybenzoyl-leucine diethylamide by chiral chromatography and 1H and 13C NMR spectroscopy.
    Chirality, 2011, Volume: 23, Issue:4

    Topics: Amino Acids; Carbon Isotopes; Chromatography; Chromatography, High Pressure Liquid; Dinitrobenzenes; Hydrogen; Indicators and Reagents; Kinetics; Leucine; Magnetic Resonance Spectroscopy; Molecular Structure; Sensitivity and Specificity; Stereoisomerism

2011
Precision and accuracy in the quantitative analysis of biological samples by accelerator mass spectrometry: application in microdose absolute bioavailability studies.
    Analytical chemistry, 2011, Jul-15, Volume: 83, Issue:14

    Topics: Administration, Oral; Adult; Antiviral Agents; Calibration; Chromatography, Liquid; Cyclopropanes; Dipeptides; Humans; Injections, Intravenous; Leucine; Male; Middle Aged; Proline; Reproducibility of Results; Sensitivity and Specificity; Sulfones; Tandem Mass Spectrometry; Urea; Young Adult

2011
Identification and interaction of amino acids with leucine-anthracene reagent by TLC and spectrophotometry: experimental and theoretical studies.
    Journal of chromatographic science, 2011, Volume: 49, Issue:8

    Topics: Amino Acids; Anthracenes; Chromatography, Thin Layer; Leucine; Methanol; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Plant Proteins; Protein Binding; Sensitivity and Specificity; Solutions

2011
[Determination of ubenimex in human plasma by HPLC-MS/MS].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2012, Volume: 43, Issue:4

    Topics: Adjuvants, Immunologic; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Humans; Leucine; Sensitivity and Specificity; Tandem Mass Spectrometry

2012
Insulin resistance and protein metabolism in chronic hemodialysis patients.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2013, Volume: 23, Issue:3

    Topics: Adult; Aged; Amino Acids; Black or African American; Blood Glucose; Body Composition; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Leucine; Male; Middle Aged; Proteins; Renal Dialysis; Sarcopenia; Sensitivity and Specificity

2013
Stability studies of recombinant Saccharomyces cerevisiae in the presence of varying selection pressure.
    Biotechnology and bioengineering, 2002, Jun-05, Volume: 78, Issue:5

    Topics: beta-Galactosidase; Bioreactors; Cell Count; Cells, Cultured; Computer Simulation; Culture Media; Gene Expression Regulation, Fungal; Leucine; Models, Biological; Plasmids; Recombinant Proteins; Recombination, Genetic; Saccharomyces cerevisiae; Selection, Genetic; Sensitivity and Specificity; Sucrose

2002
A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases.
    Analytical biochemistry, 2002, Sep-01, Volume: 308, Issue:1

    Topics: Ammonia; Animals; Cytosol; Glutamate Dehydrogenase; Humans; Leucine; Male; Mitochondria; Organ Specificity; Radiochemistry; Rats; Rats, Inbred F344; Recombinant Proteins; Sensitivity and Specificity; Spectrophotometry; Substrate Specificity; Transaminases

2002
Determination of a peptide-doxorubicin, prostate-specific antigen activated prodrug, and its active metabolites in human plasma using high-performance liquid chromatography with fluorescence detection. Stabilization of the peptide prodrug with EDTA.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Nov-15, Volume: 780, Issue:1

    Topics: Chromatography, High Pressure Liquid; Doxorubicin; Edetic Acid; Leucine; Prodrugs; Prostate-Specific Antigen; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2002
A method for the determination of enzyme mass loading on an electrode surface through radioisotope labelling.
    Biosensors & bioelectronics, 2002, Volume: 17, Issue:11-12

    Topics: Aniline Compounds; Biosensing Techniques; Catalysis; Coated Materials, Biocompatible; Electrochemistry; Enzyme Activation; Enzymes, Immobilized; Equipment Design; Isotope Labeling; L-Lactate Dehydrogenase; Leucine; Microscopy, Electron, Scanning; Recombinant Proteins; Scintillation Counting; Sensitivity and Specificity

2002
Side chain NMR assignments in the membrane protein OmpX reconstituted in DHPC micelles.
    Journal of biomolecular NMR, 2002, Volume: 23, Issue:4

    Topics: Amino Acids; Bacterial Outer Membrane Proteins; Cold Temperature; Escherichia coli Proteins; Hydrolases; Isoleucine; Isotopes; Leucine; Membranes, Artificial; Micelles; Nuclear Magnetic Resonance, Biomolecular; Phospholipid Ethers; Sensitivity and Specificity; Valine

2002
Biological specificities of 4,5-dehydro analogues of isoleucine and alloisoleucine.
    The Journal of biological chemistry, 1961, Volume: 236

    Topics: Isoleucine; Leucine; Organic Chemicals; Sensitivity and Specificity

1961
Model to assess muscle protein turnover: domain of validity using amino acyl-tRNA vs. surrogate measures of precursor pool.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 285, Issue:5

    Topics: Adult; Arteries; Biological Transport; Carbon Isotopes; False Negative Reactions; False Positive Reactions; Humans; Keto Acids; Kinetics; Leucine; Mathematics; Models, Biological; Muscle Proteins; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; RNA, Transfer, Amino Acyl; Sensitivity and Specificity; Veins

2003
Influence of the polydispersity of polymeric surfactants on the enantioselectivity of chiral compounds in micellar electrokinetic chromatography.
    Langmuir : the ACS journal of surfaces and colloids, 2004, Aug-03, Volume: 20, Issue:16

    Topics: Chromatography, Micellar Electrokinetic Capillary; Leucine; Magnetic Resonance Spectroscopy; Micelles; Molecular Structure; Molecular Weight; Particle Size; Polymers; Sensitivity and Specificity; Spectrometry, Fluorescence; Stereoisomerism; Surface Properties; Surface-Active Agents; Time Factors; Ultracentrifugation

2004
Optimization of 13C direct detection NMR methods.
    Journal of biomolecular NMR, 2004, Volume: 30, Issue:2

    Topics: Carbon Isotopes; Leucine; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Sodium Chloride; Solutions

2004
The in vitro performance of laser fluorescence and caries-detector dye for detecting residual carious dentin during tooth preparation.
    Quintessence international (Berlin, Germany : 1985), 2005, Volume: 36, Issue:6

    Topics: Coloring Agents; Dental Caries; Dental Caries Activity Tests; Dental Cavity Preparation; Dentin; Fluorescence; Glutamic Acid; Humans; Lasers; Leucine; Lysine; Microscopy, Polarization; Molar; Observer Variation; Reproducibility of Results; Sensitivity and Specificity

2005
Distinction of Leu and Ile Using a Ruthenium(II) complex by MALDI-LIFT-TOF/TOF-MS analysis.
    Analytical chemistry, 2005, Oct-15, Volume: 77, Issue:20

    Topics: Isoleucine; Leucine; Molecular Structure; Organometallic Compounds; Ruthenium; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2005
High-temperature liquid chromatography coupled on-line to a continuous-flow biochemical screening assay with electrospray ionization mass spectrometric detection.
    Analytical chemistry, 2005, Dec-15, Volume: 77, Issue:24

    Topics: Cathepsin B; Chromatography, Liquid; Dipeptides; Drug Stability; Hot Temperature; Leucine; Leupeptins; Online Systems; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tea

2005
In-vivo metabolism of VLDL-apolipoprotein-B, -CIII and -E in normolipidemic subjects.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2006, Volume: 16, Issue:3

    Topics: Adult; Apolipoprotein C-III; Apolipoproteins B; Apolipoproteins C; Apolipoproteins E; Area Under Curve; Cholesterol, VLDL; Chromatography, High Pressure Liquid; Humans; Leucine; Lipoproteins; Lipoproteins, VLDL; Male; Sensitivity and Specificity

2006
Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method.
    Malaria journal, 2006, Jul-05, Volume: 5

    Topics: Animals; Anopheles; Enzyme-Linked Immunosorbent Assay; Female; Insecticide Resistance; Leucine; Mutation; Oligonucleotide Probes; Phenylalanine; Polymerase Chain Reaction; Pyrethrins; Sensitivity and Specificity; Tanzania

2006
Evaluation of denaturing high-performance liquid chromatography as a rapid detection method for identification of epidermal growth factor receptor mutations in nonsmall-cell lung cancer.
    Cancer, 2006, Dec-15, Volume: 107, Issue:12

    Topics: Arginine; Carcinoma, Non-Small-Cell Lung; Chromatography, High Pressure Liquid; DNA Mutational Analysis; ErbB Receptors; Humans; Leucine; Lung Neoplasms; Mutation; Nucleic Acid Denaturation; Sensitivity and Specificity

2006
Carrot antifreeze protein does not exhibit the polygalacturonase-inhibiting activity of PGIP family.
    Yi chuan xue bao = Acta genetica Sinica, 2006, Volume: 33, Issue:11

    Topics: Alternaria; Amino Acid Motifs; Amino Acid Sequence; Antifreeze Proteins; Cloning, Molecular; Daucus carota; DNA, Complementary; Leucine; Models, Molecular; Molecular Sequence Data; Plant Proteins; Polygalacturonase; Protein Binding; Protein Conformation; Repetitive Sequences, Amino Acid; Sensitivity and Specificity; Sequence Alignment; Two-Hybrid System Techniques

2006
Development of a liquid chromatography/tandem mass spectrometry assay for the determination of bestatin in rat plasma and its application to a pharmacokinetic study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, May-01, Volume: 850, Issue:1-2

    Topics: Animals; Chromatography, High Pressure Liquid; Female; Leucine; Male; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2007
Escherichia coli enzyme IIANtr regulates the K+ transporter TrkA.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Mar-06, Volume: 104, Issue:10

    Topics: Biological Transport; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Leucine; Ligands; Models, Biological; Mutation; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Potassium; Protein Binding; Receptor, trkA; Sensitivity and Specificity; Surface Plasmon Resonance; Time Factors

2007
Racemic beta sheets in biochirogenesis.
    Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:20

    Topics: Amines; Hydrogen Bonding; Kinetics; Leucine; Oligopeptides; Protein Structure, Secondary; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Valine

2007
Asymmetric methyl group labeling as a probe of membrane protein homo-oligomers by NMR spectroscopy.
    Journal of the American Chemical Society, 2008, Feb-27, Volume: 130, Issue:8

    Topics: Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Oligonucleotide Probes; Protein Conformation; Protein Structure, Secondary; Reference Standards; Sensitivity and Specificity

2008
Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry.
    Clinical chemistry, 1995, Volume: 41, Issue:1

    Topics: False Positive Reactions; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Mass Spectrometry; Neonatal Screening; Paper; Phenylalanine; Reference Values; Sensitivity and Specificity; Valine

1995
Simultaneous determination of plasma levels of alpha-ketoisocaproic acid and leucine and evaluation of alpha-[1-13C]ketoisocaproic acid and [1-13C]leucine enrichment by gas chromatography-mass spectrometry.
    Analytical biochemistry, 1994, Aug-01, Volume: 220, Issue:2

    Topics: Carbon Isotopes; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Keto Acids; Leucine; Sensitivity and Specificity

1994
Analysis of femtomole concentrations of alpha-ketoisocaproic acid in brain tissue by precolumn fluorescence derivatization with 4,5-dimethoxy-1,2-diaminobenzene.
    Analytical biochemistry, 1993, Aug-15, Volume: 213, Issue:1

    Topics: Animals; Brain Chemistry; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Fluorescent Dyes; Fluorometry; Keto Acids; Leucine; Male; Microchemistry; Phenylenediamines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Swine

1993
A radio-enzymatic method for the estimation of L-leucine-specific radioactivity.
    Journal of biochemical and biophysical methods, 1993, Volume: 26, Issue:4

    Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Carbon Radioisotopes; Leucine; Radiometry; Rats; Rats, Wistar; RNA, Transfer, Leu; Sensitivity and Specificity

1993
Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry.
    Clinical chemistry, 1996, Volume: 42, Issue:3

    Topics: Blood Specimen Collection; Chromatography, High Pressure Liquid; Homocystinuria; Humans; Infant, Newborn; Isoleucine; Leucine; Mass Spectrometry; Metabolism, Inborn Errors; Methionine; Neonatal Screening; Paper; Sensitivity and Specificity

1996
Trace analysis in chiral separation of selected amino enantiomers.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:8-10

    Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Fluorometry; Leucine; Perchlorates; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Threonine

1996
Determination of [D-Ala2,D-Leu5]enkephalin and the metabolites containing C-terminal D-leucine by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Feb-21, Volume: 689, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Enkephalin, Leucine-2-Alanine; Leucine; Male; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity

1997
Gradient high-performance liquid chromatographic analysis of enkephalin peptides, their metabolites, and enzyme inhibitors using combined ultraviolet and electrochemical detection II. Application to ocular permeability studies in vitro.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, May-08, Volume: 709, Issue:1

    Topics: Aminopeptidases; Animals; Bicarbonates; Calibration; Chromatography, High Pressure Liquid; Colorimetry; Conjunctiva; Cornea; Dipeptides; Drug Combinations; Electrochemistry; Enkephalin, Methionine; Glutathione; In Vitro Techniques; Leucine; Neprilysin; Permeability; Protease Inhibitors; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Solutions; Spectrophotometry, Ultraviolet

1998
Modeling protein turnover: a module for teaching modeling.
    Advances in experimental medicine and biology, 1998, Volume: 445

    Topics: Animals; Computer Simulation; Computer-Assisted Instruction; Leucine; Linear Models; Mice; Models, Biological; Numerical Analysis, Computer-Assisted; Protein Biosynthesis; Proteins; Radioactive Tracers; Reference Values; RNA, Transfer; Sensitivity and Specificity

1998
Designing a radioisotope experiment using a dynamic, mechanistic model of protein turnover.
    Advances in experimental medicine and biology, 1998, Volume: 445

    Topics: Animals; Leucine; Mice; Models, Biological; Protein Biosynthesis; Proteins; Radioactive Tracers; Rats; RNA, Transfer, Leu; Sensitivity and Specificity

1998
Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Nov-24, Volume: 95, Issue:24

    Topics: Adenosine Diphosphate Ribose; Animals; Autoradiography; Brain; Carbon Radioisotopes; Eukaryotic Initiation Factor-2; Hibernation; Leucine; Nerve Tissue Proteins; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Protein Biosynthesis; Ribosomes; RNA, Messenger; Sciuridae; Sensitivity and Specificity; Transcription, Genetic

1998
Recycling, channeling and heterogeneous protein turnover estimation using a model of whole-body protein turnover based on leucine kinetics in rodents.
    The Journal of nutrition, 1999, Volume: 129, Issue:3

    Topics: Animals; Carbon Radioisotopes; False Negative Reactions; Kinetics; Leucine; Mice; Models, Biological; Protein Biosynthesis; Proteins; RNA, Transfer, Leu; Sensitivity and Specificity

1999
Necrotic tumor versus brain abscess: importance of amino acids detected at 1H MR spectroscopy--initial results.
    Radiology, 1999, Volume: 213, Issue:3

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Brain; Brain Abscess; Brain Neoplasms; Diagnosis, Differential; Female; Humans; Isoleucine; Leucine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Necrosis; Phantoms, Imaging; Sensitivity and Specificity; Valine

1999
Simultaneous determination of the enantiomers of leucine and [2H7]leucine in plasma by capillary gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Dec-10, Volume: 735, Issue:2

    Topics: Animals; Calibration; Gas Chromatography-Mass Spectrometry; Leucine; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Tritium

1999
Homology-based method for identification of protein repeats using statistical significance estimates.
    Journal of molecular biology, 2000, May-05, Volume: 298, Issue:3

    Topics: Algorithms; Alkyl and Aryl Transferases; Amino Acid Motifs; Animals; Ankyrins; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Cycle Proteins; Computational Biology; Databases, Factual; DNA-Binding Proteins; Farnesyltranstransferase; Genome; Guanine Nucleotide Exchange Factors; Heat-Shock Proteins; Helminth Proteins; HSP40 Heat-Shock Proteins; Humans; Leucine; Models, Molecular; Molecular Chaperones; Nuclear Proteins; Phylogeny; Protein Structure, Secondary; Proteins; Repetitive Sequences, Amino Acid; Saccharomyces cerevisiae; Sensitivity and Specificity; Sequence Alignment; Sequence Homology, Amino Acid

2000
Evaluation of a sensitive colorimetric FXIII incorporation assay. Effects of FXIII Val34Leu, plasma fibrinogen concentration and congenital FXIII deficiency.
    Thrombosis research, 2001, Apr-01, Volume: 102, Issue:1

    Topics: Amines; Amino Acid Substitution; Ammonia; Chromogenic Compounds; Clinical Chemistry Tests; Enzyme-Linked Immunosorbent Assay; Factor XIII; Factor XIII Deficiency; Fibrinogen; Humans; Kinetics; Leucine; Point Mutation; Sensitivity and Specificity; Valine

2001
Free energy of a potassium ion in a model of the channel formed by an amphipathic leucine-serine peptide.
    European biophysics journal : EBJ, 2002, Volume: 31, Issue:3

    Topics: Biomimetic Materials; Computer Simulation; Electric Conductivity; Electrochemistry; Ions; Leucine; Models, Chemical; Models, Molecular; Potassium; Potassium Channels; Protein Conformation; Sensitivity and Specificity; Serine; Surface-Active Agents; Thermodynamics

2002
Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions.
    Nature biotechnology, 2002, Volume: 20, Issue:6

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; bcl-Associated Death Protein; beta-Lactamases; Carrier Proteins; Cattle; Cell Line; Cephalosporins; DNA-Binding Proteins; Humans; Immunophilins; Kidney; Leucine; Microscopy, Fluorescence; Peptide Fragments; Peptide Library; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Protein Folding; Protein Interaction Mapping; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Reproducibility of Results; Saccharomyces cerevisiae Proteins; Sensitivity and Specificity; Smad3 Protein; TOR Serine-Threonine Kinases; Trans-Activators

2002
In vivo circumvention of human colon carcinoma resistance to bleomycin.
    Cancer research, 1992, May-15, Volume: 52, Issue:10

    Topics: Animals; Bleomycin; Colonic Neoplasms; Cysteine Proteinase Inhibitors; Drug Interactions; Drug Resistance; Female; Humans; Leucine; Lung; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Pulmonary Fibrosis; Sensitivity and Specificity; Tissue Distribution; Transplantation, Heterologous

1992
Incorporation of 2-fluorohistidine in murine protein in vivo.
    Life sciences, 1992, Volume: 51, Issue:15

    Topics: Animals; Body Weight; Brain; Carbon Radioisotopes; Cycloheximide; Dose-Response Relationship, Drug; Histidine; Kidney; Leucine; Liver; Male; Mice; Mice, Inbred BALB C; Proteins; Sensitivity and Specificity; Solubility; Tissue Distribution; Tritium

1992
Monitoring of mononuclear cell subsets isolated from the coronary sinus and the right atrium in patients after heart allograft transplantation.
    The Journal of thoracic and cardiovascular surgery, 1991, Volume: 102, Issue:2

    Topics: Antigens, CD; Biopsy; Blood; Coronary Vessels; Endocardium; Graft Rejection; Heart Atria; Heart Transplantation; Humans; Leucine; Leukocyte Count; Lymphocyte Subsets; Sensitivity and Specificity

1991
Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.
    Genes & development, 1990, Volume: 4, Issue:10

    Topics: Amino Acid Sequence; Base Sequence; Biopolymers; Cross-Linking Reagents; DNA; DNA-Binding Proteins; Genetic Vectors; Glutaral; HeLa Cells; Humans; Leucine; Molecular Sequence Data; Protein Biosynthesis; Sensitivity and Specificity; Transcription Factors; Transcription, Genetic; Vaccinia virus

1990
Drosophila chaoptin, a member of the leucine-rich repeat family, is a photoreceptor cell-specific adhesion molecule.
    The EMBO journal, 1990, Volume: 9, Issue:6

    Topics: Animals; Cell Adhesion; Cell Aggregation; Cell Membrane; Cells, Cultured; DNA; Drosophila; Drosophila Proteins; Glycolipids; Leucine; Membrane Glycoproteins; Multigene Family; Photoreceptor Cells; Sensitivity and Specificity; Time Factors; Type C Phospholipases

1990