Page last updated: 2024-11-01

ofloxacin and Sensitivity and Specificity

ofloxacin has been researched along with Sensitivity and Specificity in 98 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"To evaluate performance of thin layer agar (TLA) 7H11 method for detection of ofloxacin (OFX) and kanamycin (KM) resistance in smear positive clinical specimens of patients with tuberculosis comparing the results with gold standard MGIT 960 system."3.91Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens. ( Gardezi, AH; Hussain, A; Ikram, A; Khadim, MT; Satti, L; Zaman, G, 2019)
" leprae to dapsone based on the folP1 drug resistance determining region (DRDR), rifampin (rpoB DRDR) and ofloxacin (gyrA DRDR) was evaluated using 211 clinical specimens from leprosy patients, including 156 multibacillary (MB) and 55 paucibacillary (PB) cases."3.85qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients. ( Araujo, S; Fontes, AB; Goulart, IMB; Goulart, LR; Li, W; Matsuoka, M; Rosa, PS; Scollard, DM; Suffys, P; Truman, RW; Vissa, V; Williams, DL, 2017)
"Comparative susceptibility of microflora isolates from patients with complicated urinary tract infections to cefepime, other cephalosporins, amikacin, ciprofloxacin and ofloxacin was studied."3.72[Cefepime (maxipime) in the treatment of severe urinary tract infection]. ( Derevianko, II, 2003)
"We designed a 4-way crossover, ex-vivo pharmacodynamic study to compare the bactericidal rate of amoxicillin/sulbactam (AMX-SUL), azithromycin (AZM), doxycycline (DOX) and levofloxacin (LVX) against Streptococcus pneumoniae ATCC 49619."2.71An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae. ( Arenoso, H; Bantar, C; Caruso, N; Fernández Canigia, L; Nicola, F; Soutric, J, 2004)
"The difference in PSA change between prostate cancer and non-cancer patients was not statistically significant (p = 0."1.37Antimicrobial therapy for asymptomatic patients with elevated prostate-specific antigen: can the change in prostate-specific antigen reliably guide prostate biopsy decisions? ( Abdelhamid, M; Emran, A; Kamal, A; Mosharafa, A; Torky, M, 2011)
" The single method thus developed is applied for the quantification of levofloxacin both in aqueous humour as well as pharmaceutical dosage forms (i."1.36A single reversed-phase UPLC method for quantification of levofloxacin in aqueous humour and pharmaceutical dosage forms. ( Ali, A; Aqil, M; Chander, P; Gupta, H; Khar, RK, 2010)
" The developed assay method was applied to a pharmacokinetic study in human volunteers following oral administration of 400 mg GFC tablet."1.35Development and validation of a HPLC method for simultaneous quantitation of gatifloxacin, sparfloxacin and moxifloxacin using levofloxacin as internal standard in human plasma: application to a clinical pharmacokinetic study. ( Mullangi, R; Narasu, L; Shankar, BP; Srinivas, N, 2008)
"A simple, rapid, and accurate high-performance thin-layer chromatography (HPTLC) method is described for the simultaneous determination of levofloxacin hemihydrate and ornidazole in tablet dosage form."1.34Validated HPTLC method for simultaneous estimation of levofloxacin hemihydrate and ornidazole in pharmaceutical dosage form. ( Bari, SB; Chepurwar, SB; Fursule, RA; Shirkhedkar, AA; Surana, SJ, 2007)
" CAZ combined with LVX or AMK yielded Fls indicating synergism (Fl < or = 0."1.33In vitro and in vivo synergy of levofloxacin or amikacin both in combination with ceftazidime against clinical isolates of Pseudomonas aeruginosa. ( Felici, A; Guerrini, M; Marchetti, F; Piccoli, L, 2005)
" This study evaluated the in vitro activity of two concentrations of levofloxacin (modeled for the 500 mg and 750 mg daily dose) in combination with ceftazidime, cefepime, piperacillin/tazobactam, imipenem, and tobramycin against P."1.32In vitro evaluation of the activity of two doses of Levofloxacin alone and in combination with other agents against Pseudomonas aeruginosa. ( Burgess, DS; Hall, RG; Hardin, TC, 2003)
"Levofloxacin resistance was rarely associated with MDR phenotypes."1.32The activity of levofloxacin and other antimicrobials against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999-2002. ( Blosser-Middleton, RS; Jones, ME; Karlowsky, JA; Sahm, DF; Thornsberry, C, 2003)
" Considering the major pharmacodynamic determinants for the concentration-dependent bactericidal activity of levofloxacin as applicable at the urinary level (CU/MIC of >12."1.32Urinary pharmacokinetics and theoretical pharmacodynamics of intravenous levofloxacin in intensive care unit patients treated with 500 mg b.i.d. for ventilator-associated pneumonia. ( Baldassarre, M; Brollo, L; Di Qual, E; Furlanut, M; Nascimben, E; Pavan, F; Pea, F, 2003)
"The aim of this study was to develop a rapid and sensitive method for the simultaneous determination of unbound levofloxacin in rat blood and bile using high-performance liquid chromatography coupled with microdialysis for further pharmacokinetic study."1.31Pharmacokinetic study of levofloxacin in rat blood and bile by microdialysis and high-performance liquid chromatography. ( Chen, YF; Cheng, FC; Hung, LC; Tsai, TH; Tsai, TR, 2002)
"Levofloxacin was dosed at 0 and 24 h, elimination pharmacokinetics were simulated, and viable counts were measured over 30 h."1.31Pharmacodynamics of 750 mg and 500 mg doses of levofloxacin against ciprofloxacin-resistant strains of Streptococcus pneumoniae. ( Lister, PD, 2002)
"Garenoxacin was the most active agent overall against Gram-positive organisms, with potent activity against Aerococcus spp."1.31Antimicrobial activity of a novel des-fluoro (6) quinolone, garenoxacin (BMS-284756), compared to other quinolones, against clinical isolates from cancer patients. ( Frisbee-Hume, S; Ho, DH; LeBlanc, BM; Rolston, KV; Streeter, H, 2002)
"Ciprofloxacin was used as the internal standard."1.30Rapid stereospecific high-performance liquid chromatographic determination of levofloxacin in human plasma and urine. ( Flor, SC; Juzwin, SJ; Wong, FA, 1997)
" This method was applied to the pharmacokinetic study of ofloxacin in 24 chronic obstructive pulmonary disease patients."1.29A reproducible, simple and sensitive HPLC assay for determination of ofloxacin in plasma and lung tissue. Application in pharmacokinetic studies. ( Bouvet, O; Bressolle, F; Fabre, D; Galtier, M; Kinowski, JM; Paganin, F, 1994)
" Juvenile (4- to 5-week-old) NZW were orally dosed with ofloxacin or pefloxacin (300 mg/kg of body weight for 1 day) or with pefloxacin (300 mg/kg for 7 days)."1.29Cytofluorometric analysis of chondrotoxicity of fluoroquinolone antimicrobial agents. ( Gaudin, C; Hayem, G; Kahn, MF; Levacher, M; Petit, PX; Pocidalo, JJ, 1994)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (11.22)18.2507
2000's59 (60.20)29.6817
2010's27 (27.55)24.3611
2020's1 (1.02)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Rahman, SMM1
Nasrin, R1
Rahman, A1
Ahmed, S1
Khatun, R1
Uddin, MKM1
Rahman, MM1
Banu, S1
Araujo, S1
Goulart, LR1
Truman, RW1
Goulart, IMB1
Vissa, V1
Li, W1
Matsuoka, M1
Suffys, P1
Fontes, AB1
Rosa, PS1
Scollard, DM1
Williams, DL1
Javaid, A1
Ahmad, N1
Afridi, AK1
Basit, A1
Khan, AH1
Ahmad, I1
Atif, M1
Hussain, A1
Zaman, G1
Satti, L1
Ikram, A1
Gardezi, AH1
Khadim, MT1
Yan, Z1
Yi, H1
Wang, L2
Zhou, X1
Yan, R1
Zhang, D1
Wang, S2
Su, L1
Zhou, S1
Şimşek, H1
Tarhan, G1
Cesur, S1
Ardizzoni, E1
Mulders, W1
Kotrikadze, T1
Aspindzelashvili, R1
Goginashvili, L1
Pangtey, H1
Varaine, F2
Bastard, M1
Rigouts, L1
de Jong, BC1
Huang, ZK1
Luo, Q1
Qing, C1
Deng, YT1
Xiong, GL1
Li, JM1
Pang, Y1
Dong, H1
Tan, Y1
Deng, Y1
Cai, X1
Jing, H1
Xia, H1
Li, Q1
Ou, X1
Su, B1
Li, X1
Zhang, Z2
Li, J2
Zhang, J2
Huan, S1
Zhao, Y1
Ma, Y1
Wang, Q2
Zhang, H1
Xie, L1
Chen, J1
Huang, M1
Liu, Y1
Wang, Y1
Sun, L1
Ou, N1
Sun, Y1
Xi, Z1
Srinivas, N1
Narasu, L1
Shankar, BP1
Mullangi, R1
Zorita, S1
Larsson, L1
Mathiasson, L1
Sun, HW1
Qiao, FX1
Liu, YM1
Jia, YX1
Tian, W1
He, B1
Liao, L1
Xiao, X1
Gao, S1
Wu, Y1
Ulu, ST1
Shirkhedkar, AA2
Surana, SJ2
Lin, SY1
Desmond, E1
Bonato, D1
Gross, W1
Siddiqi, S1
Cambau, E1
Allerheiligen, V1
Coulon, C1
Corbel, C1
Lascols, C1
Deforges, L1
Soussy, CJ1
Delchier, JC1
Megraud, F1
Martin, A2
Paasch, F1
Von Groll, A1
Fissette, K2
Almeida, P1
Portaels, F1
Palomino, JC2
Watabe, S1
Yokoyama, Y1
Nakazawa, K1
Shinozaki, K1
Hiraoka, R1
Takeshita, K1
Suzuki, Y2
Chang, KC1
Yew, WW2
Chan, RC1
Sousa, J1
Alves, G1
Fortuna, A1
Pena, A1
Lino, C1
Falcão, A1
Fang, PF1
Cai, HL1
Li, HD1
Zhu, RH1
Tan, QY1
Gao, W1
Xu, P1
Liu, YP1
Zhang, WY1
Chen, YC1
Zhang, F1
Aranda, A1
Mayorga, C1
Ariza, A1
Doña, I1
Rosado, A1
Blanca-Lopez, N1
Andreu, I1
Torres, MJ1
Qu, P1
Lei, J1
Zhang, L1
Ouyang, R1
Ju, H1
Gupta, H1
Aqil, M1
Khar, RK1
Ali, A1
Chander, P1
Chen, X2
Kong, F1
Li, C1
Gilbert, GL1
Torky, M1
Mosharafa, A1
Emran, A1
Kamal, A1
Abdelhamid, M1
Attia, MS1
Essawy, AA1
Youssef, AO1
Mostafa, MS1
Meredith, SA1
Smith, PJ1
Norman, J1
Wiesner, L1
Said, HM1
Kock, MM1
Ismail, NA1
Baba, K1
Omar, SV1
Osman, AG1
Hoosen, AA1
Ehlers, MM1
Ramos, E1
de Rijk, P1
Salem, AA2
Mossa, HA2
Byrro, RM1
de Oliveira Fulgêncio, G1
da Silva Cunha, A1
César, IC1
Chellini, PR1
Pianetti, GA1
Barnard, M1
Warren, R1
Gey Van Pittius, N1
van Helden, P1
Bosman, M1
Streicher, E1
Coetzee, G1
O'Brien, R1
Sun, H2
Wang, H1
Ge, X1
Jin, J1
Shen, Y1
Fan, X1
Diao, N1
Wang, F1
Weng, X1
Zhang, W1
Cheng, FC1
Tsai, TR1
Chen, YF1
Hung, LC1
Tsai, TH1
Burgess, DS2
Nathisuwan, S1
Lister, PD1
Ali, MS1
Ghori, M1
Saeed, A1
Rolston, KV1
Frisbee-Hume, S1
LeBlanc, BM1
Streeter, H1
Ho, DH1
Doğan, HS1
Sahin, A1
Cetinkaya, Y1
Akdoğan, B1
Ozden, E1
Kendi, S1
Hall, RG1
Hardin, TC1
Horii, T1
Monji, A1
Morita, M1
Muramatsu, H1
Kondo, Y1
Doi, M1
Takeshita, A1
Kanno, T1
Maekawa, M1
Cottagnoud, P1
Cottagnoud, M1
Acosta, F1
Flatz, L1
Kühn, F1
Stucki, A1
Entenza, J1
Derevianko, II1
Djabarouti, S1
Boselli, E1
Allaouchiche, B1
Ba, B1
Nguyen, AT1
Gordien, JB1
Bernadou, JM1
Saux, MC1
Breilh, D1
Jones, ME1
Blosser-Middleton, RS1
Thornsberry, C1
Karlowsky, JA1
Sahm, DF1
Garrison, MW1
Schimmels, JA1
Madaras-Kelly, KJ1
Pea, F1
Pavan, F1
Di Qual, E1
Brollo, L1
Nascimben, E1
Baldassarre, M1
Furlanut, M1
Schito, AM1
Schito, GC1
Viale, P1
Scudeller, L1
Cristini, F1
Bantar, C1
Nicola, F1
Arenoso, H1
Soutric, J1
Caruso, N1
Fernández Canigia, L1
Fajardo, TT1
Villahermosa, LG1
Cruz, EC1
Cellona, RV1
Balagon, MV1
Abalos, RM1
Gelber, RH1
Drago, L1
De Vecchi, E1
Nicola, L1
Legnani, D1
Prenna, M1
Ripa, S1
Sulochana, S1
Rahman, F1
Paramasivan, CN1
Ambrosi, A1
Antiochia, R1
Campanella, L1
Dragone, R1
Lavagnini, I1
Soledad García, M1
Isabel Albero, M1
Sánchez-Pedreño, C1
Salem Abuherba, M1
Espinosa-Mansilla, A2
Peña, AM1
Gómez, DG1
Salinas, F1
Santoro, MI1
Kassab, NM1
Singh, AK1
Kedor-Hackmam, ER1
Piccoli, L1
Guerrini, M1
Felici, A1
Marchetti, F1
Barsoum, BN1
Muñoz de la Peña, A1
Cañada-Cañada, F1
González Gómez, D1
Serra, AL1
Klein, M1
Nitsch, D1
Dürr, D1
Wermuth, B1
Frey, FJ1
Zivanovic, Lj1
Zigic, G1
Zecevic, M1
Schulte, S1
Ackermann, T1
Bertram, N1
Sauerbruch, T1
Paar, WD1
Li, L1
Peng, X1
Wang, Z2
Kuang, W1
Tan, J1
Li, K1
Yan, H1
Row, KH1
Zhu, Y1
Ding, S1
He, F1
Beier, RC1
Jiang, H1
Feng, C1
Wan, Y1
Zhang, S1
Kai, Z1
Yang, X1
Shen, J1
Zhou, ZL1
Yang, M1
Yu, XY1
Peng, HY1
Shan, ZX1
Chen, SZ1
Lin, QX1
Liu, XY1
Chen, TF1
Zhou, SF1
Lin, SG1
Lecordier, J1
Lahet, JJ1
Courderot-Masuyer, C1
Beaudoin, E1
Chaillot, B1
Chepurwar, SB1
Bari, SB1
Fursule, RA1
Bao, D1
Truong, TT1
Renick, PJ1
Pulse, ME1
Weiss, WJ1
Cheng, GW1
Wu, HL1
Huang, YL1
Fabre, D1
Bressolle, F1
Kinowski, JM1
Bouvet, O1
Paganin, F1
Galtier, M1
Hayem, G1
Petit, PX1
Levacher, M1
Gaudin, C1
Kahn, MF1
Pocidalo, JJ1
Macek, J1
Ptácek, P1
Doern, GV1
Torres, BB1
Jankins, M1
Jones, RN1
Basci, NE1
Hanioglu-Kargi, S1
Soysal, H1
Bozkurt, A1
Kayaalp, SO1
Wong, FA1
Juzwin, SJ1
Flor, SC1
Visalli, MA1
Jacobs, MR1
Appelbaum, PC1
Jakubicz, P1
Leszczyńska, K1
Zhang, SS1
Liu, HX1
Yuan, ZB1
Yu, CL1
Zeng, S1
Zhong, J1
Pan, L1
Li, Y1
Hooper, DC1
Singh, HB1
Katoch, K1
Natrajan, M1
Sharma, RK1
Gupta, UD1
Sharma, VD1
Singh, D1
Chauhan, DS1
Srivastava, K1
Katoch, VM1
Horstkötter, C1
Blaschke, G1
Karazanashvili, G1
Managadze, L1
Presterl, E1
Mueller-Uri, P1
Grisold, A1
Georgopoulos, A1
Graninger, W1
Pracharktam, R1
Angkananukool, K1
Vibhagool, A1
Ryan, BM1
Mazzucco, CE1
Lawrence, LE1
Ho, H1
Warr, G1
Barrett, JF1
Frosco, M1
Chau, CH1
Liang, H1
Kays, MB1
Sowinski, KM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neutrophil and Lymphocyte Counts and the Neutrophil-to-lymphocyte Ratio as a Predictor of Fever Following Percutaneous Nephrolithotomy in Patients Without Risk Factors[NCT03774940]519 participants (Actual)Interventional2005-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for ofloxacin and Sensitivity and Specificity

ArticleYear
Rapid assays for fluoroquinolone resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:8

    Topics: Antitubercular Agents; Aza Compounds; Bacterial Proteins; DNA Gyrase; DNA, Bacterial; Drug Resistanc

2010
Levofloxacin, a broad spectrum anti-infective: from Streptococcus pneumoniae to Pseudomonas aeruginosa.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 2

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Humans; Italy; Levofloxacin; Micro

2004
New uses for new and old quinolones and the challenge of resistance.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:2

    Topics: Anti-Infective Agents; Bacterial Infections; Drug Resistance, Microbial; Fluoroquinolones; Humans; M

2000

Trials

5 trials available for ofloxacin and Sensitivity and Specificity

ArticleYear
Simultaneous quantification of antofloxacin and its major metabolite in human urine by HPLC-MS/MS, and its application to a pharmacokinetic study.
    Biomedical chromatography : BMC, 2017, Volume: 31, Issue:9

    Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Linear Mode

2017
In vitro evaluation of IgE-mediated hypersensitivity reactions to quinolones.
    Allergy, 2011, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Aza Compounds; Basophil Degranulation Test; Ciproflo

2011
Antibiotic prophylaxis in percutaneous nephrolithotomy: prospective study in 81 patients.
    Journal of endourology, 2002, Volume: 16, Issue:9

    Topics: Adult; Antibiotic Prophylaxis; Bacteriuria; Dose-Response Relationship, Drug; Drug Administration Sc

2002
An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:3

    Topics: Adult; Amoxicillin; Analysis of Variance; Azithromycin; Blood Bactericidal Activity; Colony Count, M

2004
A clinical trial of pefloxacin and ofloxacin in lepromatous leprosy.
    Leprosy review, 2004, Volume: 75, Issue:4

    Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; L

2004

Other Studies

90 other studies available for ofloxacin and Sensitivity and Specificity

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Performance of GenoType MTBDRsl assay for detection of second-line drugs and ethambutol resistance directly from sputum specimens of MDR-TB patients in Bangladesh.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Bangladesh; DNA, Bacterial; Ethambutol; Exten

2021
qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6

    Topics: Bacterial Proteins; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Leprostatic Agents;

2017
Validity of Time to Sputum Culture Conversion to Predict Cure in Patients with Multidrug-Resistant Tuberculosis: A Retrospective Single-Center Study.
    The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cohort Studies; Drug Resistance, Bacterial; Female;

2018
Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Bacteriolo

2019
Fluorescent aptasensor for ofloxacin detection based on the aggregation of gold nanoparticles and its effect on quenching the fluorescence of Rhodamine B.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2019, Oct-05, Volume: 221

    Topics: Animals; Aptamers, Nucleotide; Dynamic Light Scattering; Fluorescent Dyes; Food Analysis; Food Conta

2019
[Evaluation of second-line antituberculosis drug susceptibilities of multidrug-resistant Mycobacterium tuberculosis complex isolates by E-test method].
    Mikrobiyoloji bulteni, 2015, Volume: 49, Issue:1

    Topics: Acetamides; Antitubercular Agents; Culture Media; Drug Resistance, Multiple, Bacterial; Ethionamide;

2015
The thin-layer agar method for direct phenotypic detection of multi- and extensively drug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015, Volume: 19, Issue:12

    Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Isoniazid; Ka

2015
Evaluation of the direct nitrate reductase assay for rapid detection of extensively drug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, Volume: 20, Issue:4

    Topics: Adult; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tubercul

2016
Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China.
    Scientific reports, 2016, 05-06, Volume: 6

    Topics: Amikacin; China; Extensively Drug-Resistant Tuberculosis; Humans; Kanamycin; Microbial Sensitivity T

2016
Direct electrogenerated chemiluminescence detection in high-performance liquid chromatography for determination of ofloxacin.
    Analytica chimica acta, 2008, Aug-08, Volume: 623, Issue:1

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Humans; Luminescent Measurements

2008
Development and validation of a HPLC method for simultaneous quantitation of gatifloxacin, sparfloxacin and moxifloxacin using levofloxacin as internal standard in human plasma: application to a clinical pharmacokinetic study.
    Biomedical chromatography : BMC, 2008, Volume: 22, Issue:11

    Topics: Administration, Oral; Analytic Sample Preparation Methods; Aza Compounds; Chromatography, High Press

2008
Comparison of solid-phase sorbents for the determination of fluoroquinolone antibiotics in wastewater.
    Journal of separation science, 2008, Volume: 31, Issue:16-17

    Topics: Adsorption; Anti-Bacterial Agents; Cation Exchange Resins; Chromatography, High Pressure Liquid; Cip

2008
Recognition mechanism of water-compatible molecularly imprinted solid-phase extraction and determination of nine quinolones in urine by high performance liquid chromatography.
    Journal of chromatography. A, 2008, Nov-28, Volume: 1212, Issue:1-2

    Topics: Binding Sites; Chromatography, High Pressure Liquid; Computer Simulation; Humans; Hydrogen Bonding;

2008
Determination of quinolone antibiotics in urine by capillary electrophoresis with chemiluminescence detection.
    Journal of separation science, 2008, Volume: 31, Issue:21

    Topics: Anti-Infective Agents; Ciprofloxacin; Electrophoresis, Capillary; Humans; Luminescent Measurements;

2008
Monitoring of Mycoplasma genitalium growth and evaluation of antibacterial activity of antibiotics tetracycline and levofloxacin using a wireless magnetoelastic sensor.
    Biosensors & bioelectronics, 2009, Mar-15, Volume: 24, Issue:7

    Topics: Anti-Bacterial Agents; Biosensing Techniques; Cell Proliferation; Colony Count, Microbial; Drug Eval

2009
Rapid and sensitive spectrofluorimetric determination of enrofloxacin, levofloxacin and ofloxacin with 2,3,5,6-tetrachloro-p-benzoquinone.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Volume: 72, Issue:5

    Topics: Anti-Bacterial Agents; Chloranil; Enrofloxacin; Fluoroquinolones; Fungicides, Industrial; Levofloxac

2009
Quantitative determination of levofloxacin hemihydrate in bulk and tablets by UV-spectrophotometry and first order derivative methods.
    Pakistan journal of pharmaceutical sciences, 2009, Volume: 22, Issue:3

    Topics: Anti-Bacterial Agents; Calibration; Levofloxacin; Ofloxacin; Quality Control; Sensitivity and Specif

2009
Multicenter evaluation of Bactec MGIT 960 system for second-line drug susceptibility testing of Mycobacterium tuberculosis complex.
    Journal of clinical microbiology, 2009, Volume: 47, Issue:11

    Topics: Amikacin; Antitubercular Agents; Capreomycin; Ethionamide; Humans; Levofloxacin; Microbial Sensitivi

2009
Evaluation of a new test, genotype HelicoDR, for molecular detection of antibiotic resistance in Helicobacter pylori.
    Journal of clinical microbiology, 2009, Volume: 47, Issue:11

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Clarithromycin; DNA Gyrase; DNA, Bacterial; Drug Resistan

2009
Thin-layer agar for detection of resistance to rifampicin, ofloxacin and kanamycin in Mycobacterium tuberculosis isolates.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2009, Volume: 13, Issue:10

    Topics: Agar; Anti-Bacterial Agents; Antitubercular Agents; Bacteriological Techniques; Drug Resistance, Bac

2009
Simultaneous measurement of pazufloxacin, ciprofloxacin, and levofloxacin in human serum by high-performance liquid chromatography with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Jun-01, Volume: 878, Issue:19

    Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Least

2010
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.
    Biomedical chromatography : BMC, 2011, Volume: 25, Issue:5

    Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Huma

2011
Simultaneous determination of isoniazid, rifampicin, levofloxacin in mouse tissues and plasma by high performance liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Aug-15, Volume: 878, Issue:24

    Topics: Animals; Antibiotics, Antitubercular; Brain Chemistry; Chromatography, High Pressure Liquid; Female;

2010
Molecularly imprinted magnetic nanoparticles as tunable stationary phase located in microfluidic channel for enantioseparation.
    Journal of chromatography. A, 2010, Sep-24, Volume: 1217, Issue:39

    Topics: Capillary Electrochromatography; Hydrogen-Ion Concentration; Linear Models; Magnetite Nanoparticles;

2010
A single reversed-phase UPLC method for quantification of levofloxacin in aqueous humour and pharmaceutical dosage forms.
    Journal of chromatographic science, 2010, Volume: 48, Issue:6

    Topics: Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Levoflo

2010
Rapid detection of isoniazid, rifampin, and ofloxacin resistance in Mycobacterium tuberculosis clinical isolates using high-resolution melting analysis.
    Journal of clinical microbiology, 2011, Volume: 49, Issue:10

    Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Isoniaz

2011
Antimicrobial therapy for asymptomatic patients with elevated prostate-specific antigen: can the change in prostate-specific antigen reliably guide prostate biopsy decisions?
    Urologia internationalis, 2011, Volume: 87, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Asymptomatic Diseases; Biopsy; Diagnostic Errors; Drug Administration S

2011
Determination of ofloxacin using a highly selective photo probe based on the enhancement of the luminescence intensity of Eu3+--ofloxacin complex in pharmaceutical and serum samples.
    Journal of fluorescence, 2012, Volume: 22, Issue:2

    Topics: Europium; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Luminescence; Luminescent Measuremen

2012
An LC-MS/MS method for the determination of ofloxacin in 20 μl human plasma.
    Journal of pharmaceutical and biomedical analysis, 2012, Jan-25, Volume: 58

    Topics: Acetonitriles; Anti-Bacterial Agents; Calibration; Chromatography, Liquid; Drug Stability; Humans; M

2012
Evaluation of the GenoType® MTBDRsl assay for susceptibility testing of second-line anti-tuberculosis drugs.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012, Volume: 16, Issue:1

    Topics: Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; Drug Re

2012
Integrated detection of multi- and extensively drug-resistant tuberculosis using the nitrate reductase assay.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012, Volume: 16, Issue:1

    Topics: Antitubercular Agents; Colorimetry; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; E

2012
Method validation and determinations of levofloxacin, metronidazole and sulfamethoxazole in an aqueous pharmaceutical, urine and blood plasma samples using quantitative nuclear magnetic resonance spectrometry.
    Talanta, 2012, Jan-15, Volume: 88

    Topics: Humans; Levofloxacin; Magnetic Resonance Spectroscopy; Maleates; Metronidazole; Ofloxacin; Sensitivi

2012
Determination of ofloxacin in tear by HPLC-ESI-MS/MS method: comparison of ophthalmic drug release between a new mucoadhesive chitosan films and a conventional eye drop formulation in rabbit model.
    Journal of pharmaceutical and biomedical analysis, 2012, Volume: 70

    Topics: Adhesiveness; Administration, Ophthalmic; Animals; Anti-Bacterial Agents; Calibration; Chemistry, Ph

2012
Genotype MTBDRsl line probe assay shortens time to diagnosis of extensively drug-resistant tuberculosis in a high-throughput diagnostic laboratory.
    American journal of respiratory and critical care medicine, 2012, Dec-15, Volume: 186, Issue:12

    Topics: Amikacin; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Extensively Drug-

2012
Simultaneous determination of the combined drugs of ceftriaxone sodium, metronidazole, and levofloxacin in human urine by high-performance liquid chromatography.
    Journal of clinical laboratory analysis, 2012, Volume: 26, Issue:6

    Topics: Ceftriaxone; Chromatography, High Pressure Liquid; Ethylamines; Humans; Hydrogen-Ion Concentration;

2012
Underestimation of the resistance of Mycobacterium tuberculosis to second-line drugs by the new GenoType MTBDRsl test.
    The Journal of molecular diagnostics : JMD, 2013, Volume: 15, Issue:1

    Topics: Antitubercular Agents; China; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Exte

2013
Pharmacokinetic study of levofloxacin in rat blood and bile by microdialysis and high-performance liquid chromatography.
    Journal of chromatography. A, 2002, Jun-28, Volume: 961, Issue:1

    Topics: Animals; Anti-Infective Agents; Area Under Curve; Bile; Chromatography, High Pressure Liquid; Levofl

2002
Cefepime, piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin alone and in combination against Pseudomonas aeruginosa.
    Diagnostic microbiology and infectious disease, 2002, Volume: 44, Issue:1

    Topics: Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Gent

2002
Pharmacodynamics of 750 mg and 500 mg doses of levofloxacin against ciprofloxacin-resistant strains of Streptococcus pneumoniae.
    Diagnostic microbiology and infectious disease, 2002, Volume: 44, Issue:1

    Topics: Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Humans; Levofloxacin; M

2002
Simultaneous determination of ofloxacin, tetrahydrozoline hydrochloride, and prednisolone acetate by high-performance liquid chromatography.
    Journal of chromatographic science, 2002, Volume: 40, Issue:8

    Topics: Chromatography, High Pressure Liquid; Imidazoles; Ofloxacin; Prednisolone; Reference Standards; Repr

2002
Antimicrobial activity of a novel des-fluoro (6) quinolone, garenoxacin (BMS-284756), compared to other quinolones, against clinical isolates from cancer patients.
    Diagnostic microbiology and infectious disease, 2002, Volume: 44, Issue:2

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Gram-Neg

2002
In vitro evaluation of the activity of two doses of Levofloxacin alone and in combination with other agents against Pseudomonas aeruginosa.
    Diagnostic microbiology and infectious disease, 2003, Volume: 46, Issue:2

    Topics: Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Drug Synergism; Evaluation Studies as

2003
Detection of mutations in quinolone resistance-determining regions in levofloxacin- and methicillin-resistant Staphylococcus aureus: effects of the mutations on fluoroquinolone MICs.
    Diagnostic microbiology and infectious disease, 2003, Volume: 46, Issue:2

    Topics: Anti-Infective Agents; Bacterial Proteins; Base Sequence; DNA Gyrase; Drug Resistance, Multiple; Hum

2003
Meropenem prevents levofloxacin-induced resistance in penicillin-resistant pneumococci and acts synergistically with levofloxacin in experimental meningitis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2003, Volume: 22, Issue:11

    Topics: Animals; Disease Models, Animal; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Resistance,

2003
[Cefepime (maxipime) in the treatment of severe urinary tract infection].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2003, Volume: 48, Issue:7

    Topics: Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; D

2003
Determination of levofloxacin in plasma, bronchoalveolar lavage and bone tissues by high-performance liquid chromatography with ultraviolet detection using a fully automated extraction method.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Jan-05, Volume: 799, Issue:1

    Topics: Anti-Infective Agents; Automation; Bone and Bones; Bronchoalveolar Lavage Fluid; Calibration; Chroma

2004
The activity of levofloxacin and other antimicrobials against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999-2002.
    Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:4

    Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Global Health; Humans; Levofloxacin; Mi

2003
In vitro pharmacodynamic activity of gatifloxacin, gemifloxacin, moxifloxacin and levofloxacin against Streptococcus pneumoniae containing specific mutations in DNA gyrase and topoisomerase IV.
    Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:4

    Topics: Analysis of Variance; Aza Compounds; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistanc

2003
Urinary pharmacokinetics and theoretical pharmacodynamics of intravenous levofloxacin in intensive care unit patients treated with 500 mg b.i.d. for ventilator-associated pneumonia.
    Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:6

    Topics: Adult; Aged; Biological Availability; Critical Illness; Dose-Response Relationship, Drug; Drug Admin

2003
Levofloxacin: a suitable option for the infectious disease consultant.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 2

    Topics: Anti-Bacterial Agents; Communicable Diseases; Critical Illness; Cross Infection; Humans; Intensive C

2004
In vitro selection of resistance to clarithromycin in Streptococcus pneumoniae clinical isolates.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:2

    Topics: Amoxicillin; Aza Compounds; Azithromycin; Clarithromycin; Drug Resistance, Bacterial; Fluoroquinolon

2005
In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:2

    Topics: Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Mi

2005
Electrochemical determination of pharmaceuticals in spiked water samples.
    Journal of hazardous materials, 2005, Jul-15, Volume: 122, Issue:3

    Topics: Clofibric Acid; Diclofenac; Electrochemistry; Environmental Monitoring; Fresh Water; Ofloxacin; Phar

2005
Flow injection spectrophotometric determination of ofloxacin in pharmaceuticals and urine.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2005, Volume: 61, Issue:1-2

    Topics: Calibration; Ferric Compounds; Flow Injection Analysis; Humans; Ofloxacin; Pharmaceutical Preparatio

2005
HPLC determination of enoxacin, ciprofloxacin, norfloxacin and ofloxacin with photoinduced fluorimetric (PIF) detection and multiemission scanning: application to urine and serum.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Aug-05, Volume: 822, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Io

2005
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2006, Jan-23, Volume: 40, Issue:1

    Topics: Anti-Bacterial Agents; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chr

2006
In vitro and in vivo synergy of levofloxacin or amikacin both in combination with ceftazidime against clinical isolates of Pseudomonas aeruginosa.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:4

    Topics: Amikacin; Animals; Ceftazidime; Disease Models, Animal; Drug Resistance, Bacterial; Drug Synergism;

2005
Quantitative determinations of levofloxacin and rifampicin in pharmaceutical and urine samples using nuclear magnetic resonance spectroscopy.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 62, Issue:1-3

    Topics: Calibration; Dimethyl Sulfoxide; Dosage Forms; Humans; Levofloxacin; Magnetic Resonance Spectroscopy

2005
Determinations of fluoroquinolones and nonsteroidal anti-inflammatory drugs in urine by extractive spectrophotometry and photoinduced spectrofluorimetry using multivariate calibration.
    Analytical biochemistry, 2005, Dec-15, Volume: 347, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Analytical; Ciprofloxacin; Diclofenac

2005
A puzzling case of high serum creatinine in a healthy woman.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Creatinine; Drug Administration Schedule; False Positive Reactions; Fe

2006
Investigation of chromatographic conditions for the separation of ofloxacin and its degradation products.
    Journal of chromatography. A, 2006, Jun-30, Volume: 1119, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Ofloxacin; Reproducibility of Results; Sensitivity and Specifi

2006
Determination of the newer quinolones levofloxacin and moxifloxacin in plasma by high-performance liquid chromatography with fluorescence detection.
    Journal of chromatographic science, 2006, Volume: 44, Issue:4

    Topics: Anti-Bacterial Agents; Aza Compounds; Chromatography, High Pressure Liquid; Fluoroquinolones; Levofl

2006
Flow-injection chemiluminescence determination of ofloxacin and levofloxacin in pharmaceutical preparations and biological fluids.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2006, Volume: 22, Issue:8

    Topics: Anti-Infective Agents, Urinary; Cerium; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical;

2006
A preliminary study on the occurrence and behavior of sulfonamides, ofloxacin and chloramphenicol antimicrobials in wastewaters of two sewage treatment plants in Guangzhou, China.
    The Science of the total environment, 2006, Dec-01, Volume: 371, Issue:1-3

    Topics: Anti-Bacterial Agents; China; Chloramphenicol; Chromatography, High Pressure Liquid; Ofloxacin; Repr

2006
Rapid chiral separation and impurity determination of levofloxacin by ligand-exchange chromatography.
    Analytica chimica acta, 2007, Feb-12, Volume: 584, Issue:1

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Levofloxacin; L

2007
Development of a monoclonal antibody-based broad-specificity ELISA for fluoroquinolone antibiotics in foods and molecular modeling studies of cross-reactive compounds.
    Analytical chemistry, 2007, Jun-15, Volume: 79, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibody Specificity; Ciprofloxacin; Enroflo

2007
A rapid and simple high-performance liquid chromatography method for the determination of human plasma levofloxacin concentration and its application to bioequivalence studies.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:10

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Chrom

2007
Determination of acid base balance and oil water partition coefficient of an atopy patch test of levofloxacin.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2008, Volume: 62, Issue:2

    Topics: Acid-Base Equilibrium; Anti-Bacterial Agents; Drug Hypersensitivity; Humans; Levofloxacin; Ofloxacin

2008
Validated HPTLC method for simultaneous estimation of levofloxacin hemihydrate and ornidazole in pharmaceutical dosage form.
    Journal of chromatographic science, 2007, Volume: 45, Issue:8

    Topics: Amebicides; Anti-Bacterial Agents; Calibration; Chromatography, Thin Layer; Dosage Forms; Levofloxac

2007
Simultaneous determination of rifampicin and levofloxacin concentrations in catheter segments from a mouse model of a device-related infection by liquid chromatography/electrospray ionization tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2008, Mar-13, Volume: 46, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Catheters, Indwelling; Chromatography, High Pressure Liquid; Disease

2008
Simultaneous determination of malondialdehyde and ofloxacin in plasma using an isocratic high-performance liquid chromatography/fluorescence detection system.
    Analytica chimica acta, 2008, Jun-02, Volume: 616, Issue:2

    Topics: Calibration; Chromatography, High Pressure Liquid; Fluorescence; Humans; Hydrogen-Ion Concentration;

2008
A reproducible, simple and sensitive HPLC assay for determination of ofloxacin in plasma and lung tissue. Application in pharmacokinetic studies.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:11

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Lung; Lung Diseases, Obstructive; Oflo

1994
Cytofluorometric analysis of chondrotoxicity of fluoroquinolone antimicrobial agents.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Animals; Anti-Infective Agents; Cartilage Diseases; Cartilage, Articular; Flow Cytometry; Fluorescen

1994
Determination of ofloxacin in human plasma using high-performance liquid chromatography and fluorescence detection.
    Journal of chromatography. B, Biomedical applications, 1995, Nov-17, Volume: 673, Issue:2

    Topics: Acetonitriles; Anti-Infective Agents; Chemical Precipitation; Chromatography, High Pressure Liquid;

1995
Accurate characterization of ofloxacin susceptibility with Enterobacteriaceae using a modified GNS F6 card and the bioMerieux Vitek System.
    Diagnostic microbiology and infectious disease, 1996, Volume: 25, Issue:3

    Topics: Anti-Infective Agents; Bacteriological Techniques; Ciprofloxacin; Enterobacteriaceae; Humans; Microb

1996
Determination of ofloxacin in human aqueous humour by high-performance liquid chromatography with fluorescence detection.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:5

    Topics: Anti-Infective Agents; Aqueous Humor; Chromatography, Liquid; Humans; Ofloxacin; Sensitivity and Spe

1997
Rapid stereospecific high-performance liquid chromatographic determination of levofloxacin in human plasma and urine.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:6

    Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Drug Stability; Humans; Levofloxacin; L

1997
Susceptibility of twenty penicillin-susceptible and -resistant pneumococci to levofloxacin, ciprofloxacin, ofloxacin, erythromycin, azithromycin, and clarithromycin by MIC and time-kill.
    Diagnostic microbiology and infectious disease, 1997, Volume: 28, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteriological Techniques; Ciprofloxaci

1997
[Occurrence of Moraxella catarrhalis in patients with respiratory tract infections].
    Medycyna doswiadczalna i mikrobiologia, 1997, Volume: 49, Issue:1-2

    Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin Resistance; Drug Resistance, Microbial; Hu

1997
A reproducible, simple, and sensitive high-performance capillary electrophoresis method for simultaneous determination of capreomycin, ofloxacin and pasiniazide in urine.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:4-5

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Capreomycin; Electrophoresis, Capillary; Humans; Isoniazi

1998
High-performance liquid chromatography separation and quantitation of ofloxacin enantiomers in rat microsomes.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, May-14, Volume: 728, Issue:1

    Topics: Animals; Anti-Infective Agents; Calibration; Chromatography, High Pressure Liquid; Glucuronosyltrans

1999
Effect of treatment on PCR positivity in multibacillary leprosy patients treated with conventional and newer drugs ofloxacin and minocycline.
    Acta leprologica, 1999, Volume: 11, Issue:4

    Topics: Adenosine Triphosphate; Biopsy; Clofazimine; Dapsone; DNA, Bacterial; Drug Evaluation; Drug Therapy,

1999
Stereoselective determination of ofloxacin and its metabolites in human urine by capillary electrophoresis using laser-induced fluorescence detection.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Apr-15, Volume: 754, Issue:1

    Topics: Administration, Oral; Anti-Infective Agents; Electrophoresis, Capillary; Fluorescence; Fluoroquinolo

2001
Prostate-specific antigen (PSA) value change after antibacterial therapy of prostate inflammation, as a diagnostic method for prostate cancer screening in cases of PSA value within 4-10 ng/ml and nonsuspicious results of digital rectal examination.
    European urology, 2001, Volume: 39, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Humans; Male; Mass Screening; Middle Aged; Ofloxacin

2001
Ciprofloxacin- and methicillin-resistant staphylococcus aureus susceptible to moxifloxacin, levofloxacin, teicoplanin, vancomycin and linezolid.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:7

    Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Base Sequence; Ciprofloxaci

2001
In vitro susceptibility testing of levofloxacin and ofloxacin by microtiter plate Alamar blue against multidrug and non multidrug resistant Mycobacterium tuberculosis in Thailand.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:9

    Topics: Coloring Agents; Culture Media; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbia

2001
Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2002, Volume: 21, Issue:1

    Topics: Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Drug Resistance, Microbial; Fluor

2002
Utility of fluoroquinolones in multidrug-resistant tuberculosis (MDR-TB)--a balanced view?
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2002, Volume: 6, Issue:2

    Topics: Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Humans; Male; Microbial Sensiti

2002
Separation of levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin, trovafloxacin and cinoxacin by high-performance liquid chromatography: application to levofloxacin determination in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, May-25, Volume: 772, Issue:1

    Topics: Anti-Infective Agents; Calibration; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Conce

2002