Page last updated: 2024-12-06
3-quinuclidinone
3-Quinuclidinone is a bicyclic tertiary amine that has been studied as a potential therapeutic agent. It exhibits various pharmacological effects, including analgesic, anticonvulsant, and antidepressant activities. Its synthesis typically involves the cyclization of a suitable precursor molecule, often via a multi-step process. The unique structural features of 3-quinuclidinone contribute to its interesting pharmacological properties. Its ability to interact with various neurotransmitter receptors, such as dopamine and serotonin receptors, has sparked research into its potential therapeutic applications. Studies have focused on understanding its mechanism of action, exploring its efficacy in treating conditions like pain, seizures, and depression. The promising results obtained in preclinical studies have driven ongoing investigations to assess its safety and therapeutic potential in human subjects.'
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 19507 |
| CHEMBL ID | 377716 |
| SCHEMBL ID | 161762 |
| SCHEMBL ID | 14714953 |
| MeSH ID | M0240403 |
Synonyms (39)
| Synonym |
|---|
| AC-713 |
| BB 0256548 |
| 1-azabicyclo[2.2.2]octan-8-one |
| nsc-168448 |
| 3-quinuclidinone |
| 3-quinuclidone |
| quinuclidone |
| 1-azabicyclo[2.2.2]octan-3-one |
| 3-oxoquinuclidine |
| mkc-2 |
| nsc168448 |
| 3731-38-2 |
| quinuclidin-3-one |
| inchi=1/c7h11no/c9-7-5-8-3-1-6(7)2-4-8/h6h,1-5h |
| STL069553 |
| CHEMBL377716 |
| AKOS000119728 |
| A823593 |
| AKOS015949293 |
| unii-p4vf4g5pta |
| nsc 168448 |
| p4vf4g5pta , |
| ec 223-087-9 |
| einecs 223-087-9 |
| 1-azabicyclo(2.2.2)octan-3-one |
| FT-0616381 |
| S12072 |
| CS-B0309 |
| SCHEMBL161762 |
| J-504207 |
| quinuclidine-3-one |
| 1-aza-bicyclo[2.2.2]octan-3-one |
| DTXSID0063151 |
| quinuclidone 3 |
| SCHEMBL14714953 |
| 1-azabicyclo[2.2.2]octan-3-one, base form |
| mfcd06801385 |
| AMY25660 |
| SB36886 |
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 35.83
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 35.83 (24.57) | | Research Supply Index | 2.30 (2.92) | | Research Growth Index | 4.96 (4.65) | | Search Engine Demand Index | 42.06 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |