Page last updated: 2024-11-12

5-ethoxycarbonyl-5-methyl-1-pyrroline n-oxide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID12168495
CHEMBL ID387743
SCHEMBL ID829888
MeSH IDM0363422

Synonyms (13)

Synonym
CHEMBL387743
AKOS006293415
61856-99-3
2h-pyrrole-2-carboxylic acid, 3,4-dihydro-2-methyl-, ethyl ester, 1-oxide
SCHEMBL829888
5-ethoxycarbonyl-5-methyl-1-pyrroline n-oxide
DTXSID80479073
empo
ethyl 2-methyl-1-oxido-3,4-dihydropyrrol-1-ium-2-carboxylate
IIPNDONTVPDUFZ-UHFFFAOYSA-N ,
2-(ethoxycarbonyl)-2-methyl-3,4-dihydro-2h-pyrrole 1-oxide
2-(ethoxycarbonyl)-2-methyl-3,4-dihydro-2h-pyrrol-1-ium-1-olate
EN300-343807
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID287847Partition coefficient, log P of the compound2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Free radical trapping properties of several ethyl-substituted derivatives of 5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide (EMPO).
AID364941Antioxidant spin trapping activity assessed as half life of superoxide radical adducts using hypoxanthine / xanthine oxidase system2008Bioorganic & medicinal chemistry, Sep-01, Volume: 16, Issue:17
Spin trapping experiments with different carbamoyl-substituted EMPO derivatives.
AID364942Partition coefficient, log P in n-octanol/phosphate buffer at pH 7.02008Bioorganic & medicinal chemistry, Sep-01, Volume: 16, Issue:17
Spin trapping experiments with different carbamoyl-substituted EMPO derivatives.
AID309399Cytotoxicity against human SW480 cells after 24 hrs2007Bioorganic & medicinal chemistry letters, Oct-15, Volume: 17, Issue:20
Cytotoxicity of the novel spin trapping compound 5-ethoxycarbonyl-3,5-dimethyl-pyrroline N-oxide (3,5-EDPO) and its derivatives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.80

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.80 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index5.00 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.80)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]