Page last updated: 2024-12-06

aluminum phosphide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID30332
CHEMBL ID4524046
MeSH IDM0042248

Synonyms (40)

Synonym
aluminium fosfide [dutch]
celphide
einecs 244-088-0
celphos (indian)
rcra waste number p006
detia
detia-ex-b
un1397
hsdb 6035
celphine
detia gas ex-b
phosphures d'alumium [french]
fosfuri di alluminio [italian]
aluminium phosphide (alp)
quickphos
aluminum phosphide (alp)
epa pesticide chemical code 066501
phostoxin-a
rcra waste no. p006
al-phos
caswell no. 031
celphos
delicia gastoxin
gastion
delicia
un 1397
aluminum phosphide
aluminium phosphide
20859-73-8
alumanylidynephosphane
aluminum phosphide [un1397] [dangerous when wet]
fosfuri di alluminio
unii-e23dr6l59s
aluminium fosfide
phosphures d'alumium
aluminum phosphide pesticide
BCP11872
Q411853
CHEMBL4524046
EN300-7465394

Research Excerpts

Overview

Aluminum phosphide is an insecticide and rodenticide used to protect stored grains from rodents and other household pests. It is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage.

ExcerptReferenceRelevance
"Aluminum phosphide is a well-known hazardous agent used as an agricultural pesticide to protect stored grains from insect damage. "( Sensing of oxidative stress biomarkers: The cardioprotective effect of taurine & grape seed extract against the poisoning induced by an agricultural pesticide aluminum phosphide.
Azarmi, Y; Eghbal, MA; Ghazi Khansari, M; Mehrizi, AA; Naddafi, M; Samadi, M; Sattari, MR, 2022
)
2.36
"Aluminum phosphide (ALP) is a pesticide agent and infrequent culprit of accidental poisoning. "( Acute Heart Failure Due to Aluminum Phosphide Poisoning.
Leigh, A; Otero, D; Petrovic, M; Singh, V, 2021
)
2.36
"Aluminum phosphide (AIP) is a fumigant commonly used in agricultural areas. "( Role of automated red blood cell exchange in the treatment of aluminum phosphide poisoning: A case report and review of the literature.
Kozanoglu, İ; Özkale, M; Özkale, Y, 2022
)
2.4
"Aluminum phosphide (rice tablet) is a highly efficient agent for preserving grains against rodents and insects. "( Treatment of critical aluminum phosphide (rice tablet) poisoning with high-dose insulin: a case report.
Sedaghattalab, M, 2022
)
2.48
"Aluminum phosphide (AlP) is a low-cost insecticide that has yet to be tested for entomotoxicological significance, despite the fact that it is frequently the cause of fatal poisoning."( Reduced body length and morphological disorders in Chrysomya albiceps (Diptera: Calliphoridae) larvae reared on aluminum phosphide-treated rabbits.
Augustyniak, M; El Wakil, A; El-Ashram, S; El-Samad, LM; Toto, NA, 2022
)
1.65
"Aluminum phosphide is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage. "( Case Report: Acute Intoxication from Phosphine Inhalation.
Jian, T; Jian, X; Kan, B; Li, Y; Shi, L; Tao, Y; Wen, Z; Yu, G; Zhao, L, 2023
)
2.35
"Aluminum phosphide toxicity is a serious problem in many countries. "( Efficacy of intravenous N acetylcysteine as an adjuvant therapy in the treatment of acute aluminum phosphide Poisoning: a systematic review and meta-analysis.
Abd-ElGawad, M; Abdelmaged, WA; Alnajar, M; Alshamaly, NF; Rageh, OES; Shaker, HO, 2023
)
2.57
"Aluminum phosphide (AlP) is a popular fumigant used widely for the safe storage of food grain. "( Acute aluminum phosphide poisoning: The menace of phosphine exposure.
Banerjee, D; Bhattacharyya, R; Yadav, D, 2021
)
2.54
"Aluminum phosphide (AlP) is an insecticide and rodenticide used to protect stored grains from rodents and other household pests. "( Aluminum phosphide poisoning in Saudi Arabia over a nine-year period.
Ahmed, A; Alnasser, S; Hussain, SM; Kirdi, TS,
)
3.02
"Aluminum phosphide (AlP) is a commonly used cheap rodenticide, insecticide, and fumigant. "( Incidental Aluminum Phosphide Poisoning: Case Report and Current Management.
Çakın, Ö; Cengiz, M; Gümüş, A; Ramazanoğlu, A; Tazegul, G, 2018
)
2.31
"Aluminum phosphide is a very common suicide agent in developing countries like Nepal. "( Extracorporeal membrane oxygenation in aluminum phosphide poisoning in Nepal: a case report.
Acharya, A; Aryal, D; Bhattarai, PR; Ghimire, A; Rajbanshi, BG; Regmi, A; Sharma, A, 2018
)
2.19
"Aluminum phosphide (AlP) is a solid fumigant which is widely used for a suicide attempt in Iran. "( Ischemic stroke as a rare manifestation of aluminum phosphide poisoning: a case report.
Abedini, M; Fatehi, F; Tabrizi, N, 2014
)
2.11
"Aluminum phosphide (AlP) is a widely used fumigant and rodenticide. "( Molecular and biochemical evidences on the protective effects of triiodothyronine against phosphine-induced cardiac and mitochondrial toxicity.
Abdolghaffari, AH; Abdollahi, M; Baeeri, M; Baghaei, A; Dehpour, AR; Gooshe, M; Hassani, S; Jafari, A; Mehr, SE; Navaei-Nigjeh, M; Rezayat, SM; Solgi, R, 2015
)
1.86
"Aluminum phosphide is a lethal systemic poison with 80%-90% mortality. "( Esophageal injuries due to aluminum phosphide tablet poisoning in India.
Bharadwaj, M; Chaudhary, S; Darbari, A; Kumar, A; Singh, GP; Tandon, S, 2008
)
2.09
"Aluminum phosphide (AlP) is a solid fumigant widely used in Iran as a grain preservative. "( Hyperglycemia in acute aluminum phosphide poisoning as a potential prognostic factor.
Alfred, S; Chalaki, N; Keyler, DE; Mehrpour, O; Sedaghat, M; Shadnia, S; Soltaninejad, K, 2008
)
2.1
"Aluminum phosphide (ALP) is a pesticide that is highly toxic. "( Intra-aortic balloon pump in toxic myocarditis due to aluminum phosphide poisoning.
Adhyapak, S; Iyengar, S; Jaydev, S; Patil, C; Shetty, G; Siddaiah, L; Varghese, K, 2009
)
2.04
"Aluminum phosphide (AlP) is a lethal solid fumigant pesticide which has been recently linked to esophageal stricture formation. "( Clinical profile and outcome of aluminum phosphide-induced esophageal strictures.
Bhagat, S; Dutta, U; Kochhar, R; Nagi, B; Poornachandra, KS; Singh, K; Vaiphei, K, 2010
)
2.09
"Aluminum phosphide (AlP) is a colorless, flammable, liquefied pesticide that is commonly used to control insects, nematodes, weeds, and pathogens in crops, forests, ornamental nurseries, and wood products. "( Aluminum phosphide-induced genetic and oxidative damages in rats: attenuation by Laurus nobilis leaf extract.
Toğar, B; Türkez, H, 2013
)
3.28
"Aluminum phosphide (ALP) is a highly effective insecticide and rodenticide used frequently to protect stored grain. "( Aluminum phosphide poisoning known as rice tablet: A common toxicity in North Iran.
Feyzbakhsh, SM; Hosseinian, A; Pakravan, N; Rafiei, A, 2011
)
3.25
"Aluminum phosphide is a commonly used fumigant in the agricultural community. "( Phosphine toxicity: report of two cases and review of the literature.
Brautbar, N; Howard, J, 2002
)
1.76

Effects

Aluminum phosphide poisoning has a high mortality rate of about 90%. To date, no antidote is available.

Aluminum phosphide (ALP) has been extensively used as an economical and effective insecticide, rodenticide, and fumigant. No antidote is available.

ExcerptReferenceRelevance
"Aluminum phosphide poisoning has a high mortality rate of about 90%, and to date, no antidote is available."( Treatment of critical aluminum phosphide (rice tablet) poisoning with high-dose insulin: a case report.
Sedaghattalab, M, 2022
)
1.76
"Aluminum phosphide poisoning has a high mortality rate, and to date, no antidote is available. "( Treatment of critical aluminum phosphide (rice tablet) poisoning with high-dose insulin: a case report.
Sedaghattalab, M, 2022
)
2.48
"Aluminum phosphide poisoning has a high mortality rate of about 90%, and to date, no antidote is available."( Treatment of critical aluminum phosphide (rice tablet) poisoning with high-dose insulin: a case report.
Sedaghattalab, M, 2022
)
1.76
"Aluminum phosphide poisoning has a high mortality rate, and to date, no antidote is available. "( Treatment of critical aluminum phosphide (rice tablet) poisoning with high-dose insulin: a case report.
Sedaghattalab, M, 2022
)
2.48
"Aluminum phosphide (ALP) has been extensively used as an economical and effective insecticide, rodenticide, and fumigant. "( Pathological changes induced by phosphine poisoning: a study on 8 children.
He, G; Huang, F; Le Grange, JM; Liang, Y; Liu, Y; Tong, F; Zhou, Y; Zhu, L, 2020
)
2
"Aluminum phosphide poisoning has high mortality resulting from cardiac impairment and hemodynamic disorders. "( Reversible myocardial injury associated with aluminum phosphide poisoning.
Abidi, K; Abouqal, R; Achour, S; Akkaoui, M; Himdi, B; Madani, A; Zeggwagh, AA, 2007
)
2.04

Toxicity

ExcerptReferenceRelevance
" Autopsied heart showed changes of toxic myocarditis on histopathology."( Magnesium levels in acute cardiotoxicity due to aluminium phosphide poisoning.
Arora, B; Chugh, SN; Jaggal, KL; Malhotra, KC; Sharma, A, 1991
)
0.28
" This article reviews the toxic effects of phosphine on the lungs and central nervous system in two workers and reviews the available scientific literature."( Phosphine toxicity: report of two cases and review of the literature.
Brautbar, N; Howard, J, 2002
)
0.31
" Melatonin has been previously shown to be beneficial in reversing toxic changes in the heart."( On the mechanisms of melatonin in protection of aluminum phosphide cardiotoxicity.
Abdollahi, M; Aminjan, HH; Asghari, MH; Baeeri, M; Baghaei, A; Hassani, S; Jafari, A; Moghadamnia, AA; Moloudizargari, M; Ostad, SN; Rahimifard, M; Solgi, R, 2017
)
0.71
"4 and 1 μg/ml) and AlP (20 μg/ml) showed the ability to reduce the toxic effects of AlP."( Calcitriol attenuates the cytotoxicity induced by aluminium phosphide via inhibiting mitochondrial dysfunction and oxidative stress in rat isolated cardiomyocytes.
Hafez, AA; Jamali, Z; Khezri, S; Salimi, A; Samiei, S; Sheikhghaderi, H, 2021
)
0.62
"To evaluate AlP-induced cardiotoxicity, the animals were divided into seven groups, including the control group, the taurine group (500 mg/kg), AlP with LD50 dose, AlP + taurine 20, 50, 100, and 200 mg/kg group."( On the mechanisms of taurine in alleviating electrocardiographic, hemodynamic, and biochemical parameters following aluminum phosphide cardiotoxicity.
Abdollahi, M; Armandeh, M; Azarmi, Y; Baeeri, M; Bameri, B; Eghbal, MA; Gholami, M; Haghi-Aminjan, H; Hassani, S; Hooshangi Shayesteh, MR; Rahimifard, M; Samadi, M; Sattari, M, 2021
)
0.83
" It is suggested that nanocurcumin-based drugs be developed to reduce the toxic effects of ALP in poisoned patients."( Nanocurcumin Improves Lipid Status, Oxidative Stress, and Function of the Liver in Aluminium Phosphide-Induced Toxicity: Cellular and Molecular Mechanisms.
Fathi Jouzdani, A; Ghafouri-Khosrowshahi, A; Ghasemi, H; Kheiripour, N; Ranjbar, A; Salimi, A; Soleimani Asl, S, 2022
)
0.72

Dosage Studied

ExcerptRelevanceReference
" The clinical spectrum of poisoning varies depending upon the dosage and duration of consumption."( Aluminum Phosphide Poisoning Presenting like Acute Myocardial Infarction in a Young Girl.
Biswajit, M; Chatterjee, PK; Ghosh, S; Saurabh, S; Sharmistha, C; Shukla, P; Sudeep, KN, 2018
)
1.92
"To analyse the effects of aluminum phosphide poisoning dosage on arterial blood gases and the clinical outcome."( The Effects Of Wheat Pill Poisoning (Aluminum Phosphide) Dosage On Arterial Blood Gases And Their Clinical Outcome.
Ahmad, I; Ali Shah, SK; Ali, N; Ali, S; Islam, Z, 2023
)
1.48
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (302)

TimeframeStudies, This Drug (%)All Drugs %
pre-199029 (9.60)18.7374
1990's67 (22.19)18.2507
2000's58 (19.21)29.6817
2010's104 (34.44)24.3611
2020's44 (14.57)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 81.17

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index81.17 (24.57)
Research Supply Index5.83 (2.92)
Research Growth Index4.95 (4.65)
Search Engine Demand Index143.23 (26.88)
Search Engine Supply Index2.01 (0.95)

This Compound (81.17)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials9 (2.74%)5.53%
Reviews20 (6.08%)6.00%
Case Studies111 (33.74%)4.05%
Observational5 (1.52%)0.25%
Other184 (55.93%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]