hydroxymethyltolbutamide has been researched along with Sensitivity and Specificity in 2 studies
hydroxymethyltolbutamide: tolbutamide metabolite
4-hydroxytolbutamide : A urea that consists of 1-butylurea having a 4-hydroxymethylbenzenesulfonyl group attached at the 3-position.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tolbutamide hydroxylation was apparently inhibited by cotinine and relatively less inhibited by nicotine." | 1.30 | Inhibitory effect of nicotine and its metabolites on tolbutamide hydroxylation in rat liver microsomes. ( Ho, JW; Leung, YK, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leung, YK | 1 |
| Ho, JW | 1 |
| Hansen, LL | 1 |
| Brøsen, K | 1 |
2 other studies available for hydroxymethyltolbutamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Inhibitory effect of nicotine and its metabolites on tolbutamide hydroxylation in rat liver microsomes.
Topics: Animals; Chromatography, High Pressure Liquid; Cotinine; Fluorescence; Hydroxylation; Hypoglycemic A | 1998 |
Quantitative determination of tolbutamide and its metabolites in human plasma and urine by high-performance liquid chromatography and UV detection.
Topics: Chromatography, High Pressure Liquid; Humans; Hypoglycemic Agents; Reproducibility of Results; Sensi | 1999 |