Page last updated: 2024-08-07 10:07:03
Carbonic anhydrase 15
A carbonic anhydrase 15 that is encoded in the genome of mouse. [PRO:DNx, UniProtKB:Q99N23]
Synonyms
EC 4.2.1.1;
Carbonate dehydratase XV;
Carbonic anhydrase XV;
CA-XV
Research
Bioassay Publications (14)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (92)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 4-hydroxybenzoic acid | Mus musculus (house mouse) | Ki | 9.3200 | 1 | 1 |
| bromide | Mus musculus (house mouse) | Ki | 13,459.6000 | 1 | 5 |
| cadaverine | Mus musculus (house mouse) | Ki | 0.6500 | 1 | 1 |
| catechol | Mus musculus (house mouse) | Ki | 10.2000 | 1 | 1 |
| chlorine | Mus musculus (house mouse) | Ki | 51,543.8250 | 1 | 4 |
| coumarin | Mus musculus (house mouse) | Ki | 39.6000 | 1 | 1 |
| salicylic acid | Mus musculus (house mouse) | Ki | 7.2000 | 1 | 1 |
| 4-aminophenol | Mus musculus (house mouse) | Ki | 335.0000 | 1 | 1 |
| hydrogen carbonate | Mus musculus (house mouse) | Ki | 25,902.0500 | 1 | 4 |
| hydroquinone | Mus musculus (house mouse) | Ki | 10.6000 | 1 | 1 |
| nitrates | Mus musculus (house mouse) | Ki | 25,192.1750 | 1 | 4 |
| nitrites | Mus musculus (house mouse) | Ki | 25,565.3000 | 1 | 4 |
| phenol | Mus musculus (house mouse) | Ki | 10.5000 | 3 | 3 |
| spermidine | Mus musculus (house mouse) | Ki | 10.0000 | 1 | 1 |
| spermine | Mus musculus (house mouse) | Ki | 74.0000 | 1 | 1 |
| catechin | Mus musculus (house mouse) | Ki | 7.6800 | 1 | 1 |
| acetaminophen | Mus musculus (house mouse) | Ki | 9.2300 | 1 | 1 |
| acetazolamide | Mus musculus (house mouse) | Ki | 0.0720 | 9 | 9 |
| celecoxib | Mus musculus (house mouse) | Ki | 0.0572 | 3 | 4 |
| clioquinol | Mus musculus (house mouse) | Ki | 2.3300 | 1 | 1 |
| dichlorphenamide | Mus musculus (house mouse) | Ki | 0.0910 | 3 | 4 |
| ethoxzolamide | Mus musculus (house mouse) | Ki | 0.0543 | 3 | 4 |
| mafenide | Mus musculus (house mouse) | Ki | 2.2467 | 2 | 3 |
| methazolamide | Mus musculus (house mouse) | Ki | 0.0650 | 2 | 2 |
| resorcinol | Mus musculus (house mouse) | Ki | 385.0000 | 1 | 1 |
| resveratrol | Mus musculus (house mouse) | Ki | 2.5700 | 1 | 1 |
| imatinib | Mus musculus (house mouse) | Ki | 0.0780 | 1 | 1 |
| sulfanilamide | Mus musculus (house mouse) | Ki | 7.4428 | 3 | 4 |
| sulpiride | Mus musculus (house mouse) | Ki | 0.0730 | 1 | 1 |
| sulthiame | Mus musculus (house mouse) | Ki | 0.1150 | 2 | 6 |
| trientine | Mus musculus (house mouse) | Ki | 59.0000 | 1 | 1 |
| zonisamide | Mus musculus (house mouse) | Ki | 0.4978 | 3 | 4 |
| cyanides | Mus musculus (house mouse) | Ki | 199.9750 | 1 | 4 |
| sulfamic acid | Mus musculus (house mouse) | Ki | 127.6325 | 1 | 4 |
| 4-toluenesulfonamide | Mus musculus (house mouse) | Ki | 5.8540 | 2 | 3 |
| benzenearsonic acid | Mus musculus (house mouse) | Ki | 20,242.2675 | 1 | 4 |
| diethylenetriamine | Mus musculus (house mouse) | Ki | 105.0000 | 1 | 1 |
| carzenide | Mus musculus (house mouse) | Ki | 3.3957 | 2 | 3 |
| thiocyanate | Mus musculus (house mouse) | Ki | 10,202.5250 | 1 | 4 |
| herniarin | Mus musculus (house mouse) | Ki | 8.4000 | 1 | 1 |
| coumarin-3-carboxylic acid | Mus musculus (house mouse) | Ki | 8.8000 | 1 | 1 |
| 4-cyanophenol | Mus musculus (house mouse) | Ki | 434.0000 | 1 | 1 |
| n-(1-naphthyl)ethylenediamine | Mus musculus (house mouse) | Ki | 0.5700 | 1 | 1 |
| 1,6-diaminohexane | Mus musculus (house mouse) | Ki | 0.6600 | 1 | 1 |
| benzolamide | Mus musculus (house mouse) | Ki | 0.0777 | 2 | 3 |
| carbonates | Mus musculus (house mouse) | Ki | 23,451.5000 | 1 | 4 |
| fluorides | Mus musculus (house mouse) | Ki | 150,031.1000 | 1 | 4 |
| iodine | Mus musculus (house mouse) | Ki | 6,667.0000 | 1 | 4 |
| azides | Mus musculus (house mouse) | Ki | 16,652.4250 | 1 | 4 |
| 7-ethoxycoumarin | Mus musculus (house mouse) | Ki | 1.0000 | 1 | 1 |
| dobutamine | Mus musculus (house mouse) | Ki | 0.3900 | 1 | 1 |
| benzeneboronic acid | Mus musculus (house mouse) | Ki | 13,647.7467 | 3 | 6 |
| 4-amino-6-chloro-1,3-benzenedisulfonamide | Mus musculus (house mouse) | Ki | 0.7073 | 2 | 3 |
| brinzolamide | Mus musculus (house mouse) | Ki | 0.0410 | 2 | 3 |
| 2,4-disulfamyl-5-trifluoromethylaniline | Mus musculus (house mouse) | Ki | 0.9357 | 2 | 3 |
| 2-aminobenzenesulfonamide | Mus musculus (house mouse) | Ki | 6.1273 | 2 | 3 |
| 3,7-diazanonane-1,9-diamine | Mus musculus (house mouse) | Ki | 66.0000 | 1 | 1 |
| sulfamide | Mus musculus (house mouse) | Ki | 258.8467 | 3 | 6 |
| 5-amino-1,3,4-thiadiazole-2-sulfonamide | Mus musculus (house mouse) | Ki | 0.2355 | 3 | 4 |
| hydrogen sulfite | Mus musculus (house mouse) | Ki | 30,052.4250 | 1 | 4 |
| cyanates | Mus musculus (house mouse) | Ki | 167.0750 | 1 | 4 |
| valdecoxib | Mus musculus (house mouse) | Ki | 0.2347 | 2 | 3 |
| 1-naphthylacetylspermine | Mus musculus (house mouse) | Ki | 0.7800 | 1 | 1 |
| chlorzolamide | Mus musculus (house mouse) | Ki | 0.0780 | 2 | 3 |
| 4-(2-aminoethyl)benzenesulfonamide | Mus musculus (house mouse) | Ki | 0.7930 | 2 | 3 |
| n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide | Mus musculus (house mouse) | Ki | 0.0637 | 2 | 3 |
| lacosamide | Mus musculus (house mouse) | Ki | 0.4610 | 1 | 1 |
| bortezomib | Mus musculus (house mouse) | Ki | 2.6800 | 1 | 1 |
| resveratrol | Mus musculus (house mouse) | Ki | 9.3600 | 1 | 1 |
| 2-hydroxycinnamic acid | Mus musculus (house mouse) | Ki | 1,000.0000 | 1 | 1 |
| s 1033 | Mus musculus (house mouse) | Ki | 0.0790 | 1 | 1 |
| 7-methoxy-2-oxo-1-benzopyran-3-carboxylic acid ethyl ester | Mus musculus (house mouse) | Ki | 6.6000 | 1 | 1 |
| dorzolamide | Mus musculus (house mouse) | Ki | 0.0440 | 2 | 3 |
| topiramate | Mus musculus (house mouse) | Ki | 0.0714 | 4 | 5 |
| 6-hydroxybenzothiazide-2-sulfonamide | Mus musculus (house mouse) | Ki | 0.0770 | 2 | 3 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| histamine | Mus musculus (house mouse) | KA | 18.5000 | 1 | 1 |
| acetazolamide | Mus musculus (house mouse) | Kinact | 0.0720 | 1 | 1 |
| levodopa | Mus musculus (house mouse) | KA | 6.5000 | 1 | 1 |
| tyrosine | Mus musculus (house mouse) | KA | 8.9000 | 1 | 1 |
| phenylalanine | Mus musculus (house mouse) | KA | 33.4000 | 1 | 1 |
| histidine | Mus musculus (house mouse) | KA | 32.1000 | 1 | 1 |
| tryptophan | Mus musculus (house mouse) | KA | 13.5000 | 1 | 1 |
| aminoethylpiperazine | Mus musculus (house mouse) | KA | 10.4000 | 1 | 1 |
| D-tryptophan | Mus musculus (house mouse) | KA | 8.7000 | 1 | 1 |
| 2-(aminomethyl)pyridine | Mus musculus (house mouse) | KA | 11.6000 | 1 | 1 |
| copper histidine | Mus musculus (house mouse) | KA | 14.1000 | 1 | 1 |
| phenylalanine | Mus musculus (house mouse) | KA | 9.5000 | 1 | 1 |
| thioxolone | Mus musculus (house mouse) | Kinact | 7.8700 | 1 | 1 |
| 2-(2-aminoethyl)pyridine | Mus musculus (house mouse) | KA | 11.9000 | 1 | 1 |
| D-dopa | Mus musculus (house mouse) | KA | 4.0000 | 1 | 1 |
| 4-aminophenylalanine | Mus musculus (house mouse) | KA | 16.3000 | 1 | 1 |
| epitrate | Mus musculus (house mouse) | KA | 6.9000 | 1 | 1 |
| 4-2-Aminoethyl-morpholine | Mus musculus (house mouse) | KA | 9.3000 | 1 | 1 |