Compounds > 2-(2,4-difluorophenyl)-3-(4-(4-(2-(4-trifluoromethoxybenzyl)-2h-1,2,4-triazol-3-one-4-yl)phenyl)piperazin-1-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol
Page last updated: 2024-12-10
2-(2,4-difluorophenyl)-3-(4-(4-(2-(4-trifluoromethoxybenzyl)-2h-1,2,4-triazol-3-one-4-yl)phenyl)piperazin-1-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol
Description
You've described a complex organic molecule with a very specific structure. While I can't provide a definitive answer about its specific importance, I can break down the structure and discuss its potential significance in research:
**Understanding the Structure:**
* **Key components:** This molecule is a complex combination of several functional groups:
* **Phenyl rings:** Multiple aromatic rings with fluorine substitutions (2,4-difluorophenyl and 4-(4-(2-(4-trifluoromethoxybenzyl)-2H-1,2,4-triazol-3-one-4-yl)phenyl)
* **Heterocyclic rings:** Triazole rings (1H-1,2,4-triazol-1-yl and 2H-1,2,4-triazol-3-one-4-yl)
* **Piperazine ring:** A six-membered ring containing nitrogen atoms.
* **Alcohol group:** A hydroxyl group (OH)
* **Substitutions:** This molecule has several fluorine substitutions, a trifluoromethoxybenzyl group, and a triazolone group. These features can significantly impact the molecule's properties.
**Possible Research Significance:**
Given its complex structure and multiple functional groups, this molecule could be relevant in several research areas, including:
* **Medicinal chemistry:**
* **Drug development:** The presence of heterocyclic rings, particularly triazoles, is often associated with biological activity and is frequently seen in drug candidates.
* **Targeting specific receptors:** The molecule's structure suggests it might bind to certain receptors or enzymes, potentially leading to therapeutic applications.
* **Antimicrobial activity:** Triazoles are known for their antimicrobial properties, and this molecule might exhibit similar activity.
* **Material science:** The combination of aromatic rings and functional groups could create a material with interesting properties, such as conductivity, fluorescence, or even self-assembly behavior.
* **Organic synthesis:** The molecule's structure serves as a building block for creating new and more complex molecules with potentially unique properties.
**How to Find More Information:**
To understand the specific research significance of this molecule, you would need to know:
* **Its purpose:** Was it synthesized for a specific application, like a drug candidate or a material component?
* **Its properties:** What are its physical and chemical properties, like solubility, melting point, or spectral data?
* **Published research:** Has this molecule been studied and published in scientific literature?
**Searching for Information:**
* **Chemical databases:** Databases like PubChem or ChemSpider might have information about the molecule if it has been registered.
* **Scientific journals:** Search for the molecule's name or related keywords in scientific databases like Scopus or Web of Science.
* **Patent databases:** If the molecule is associated with a patent, you can find information about its intended use.
Remember, understanding the specific context of this molecule is essential to fully appreciate its research significance.
Syn 2869: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 3081359 |
CHEMBL ID | 5194034 |
SCHEMBL ID | 1651314 |
MeSH ID | M0304716 |
Synonyms (8)
Synonym |
210562-98-4 |
3h-1,2,4-triazol-3-one, 4-(4-(4-((1r,2r)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-((4-(trifluoromethoxy)phenyl)methyl)- |
2-(2,4-difluorophenyl)-3-(4-(4-(2-(4-trifluoromethoxybenzyl)-2h-1,2,4-triazol-3-one-4-yl)phenyl)piperazin-1-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol |
syn 2869 |
SCHEMBL1651314 |
DTXSID80175280 |
CHEMBL5194034 |
heaoyzudbiusjn-jpzyqriqsa-n |
Research Excerpts
Bioavailability
Excerpt | Reference | Relevance |
"34 microg/ml, respectively, in BALB/c mice after administration of an oral dose of 50 mg/kg of body weight, with bioavailability being greater than 45% in all mice." | ( Interspecies comparison of pharmacokinetics of the novel triazole antifungal agent SYN-2869 and its derivatives. Bu, HZ; Daneshtalab, M; Khan, JK; Micetich, RG; Montaseri, H; Poglod, M; Salama, SM; Zuo, Z, 2000) | 0.31 |
Research
Studies (9)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (44.44) | 18.2507 |
2000's | 4 (44.44) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (11.11) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 11.91
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 11.91 (24.57) | Research Supply Index | 2.30 (2.92) | Research Growth Index | 4.21 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (11.11%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 8 (88.89%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |