Proteins > Solute carrier family 22 member 2
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Solute carrier family 22 member 2
A solute carrier family 22 member 2 that is encoded in the genome of rat. [OMA:Q9R0W2, PRO:DNx]
Synonyms
Organic cation transporter 2;
rOCT2
Research
Bioassay Publications (16)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (34)
Drugs with Inhibition Measurements
Drugs with Other Measurements
Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus.The Journal of biological chemistry, , Nov-09, Volume: 276, Issue:45, 2001
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat.The Journal of biological chemistry, , Sep-22, Volume: 275, Issue:38, 2000
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.Biochimica et biophysica acta, , Mar-04, Volume: 1417, Issue:2, 1999
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Selective substrates for non-neuronal monoamine transporters.Molecular pharmacology, , Volume: 56, Issue:1, 1999
A transfected cell model for the renal toxin transporter, rOCT2.Toxicological sciences : an official journal of the Society of Toxicology, , Volume: 47, Issue:2, 1999
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.Biochimica et biophysica acta, , Mar-04, Volume: 1417, Issue:2, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Selective substrates for non-neuronal monoamine transporters.Molecular pharmacology, , Volume: 56, Issue:1, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.Drug metabolism and disposition: the biological fate of chemicals, , Volume: 33, Issue:4, 2005
The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.The Journal of pharmacology and experimental therapeutics, , Volume: 303, Issue:3, 2002
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat.The Journal of biological chemistry, , Sep-22, Volume: 275, Issue:38, 2000
rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger.The American journal of physiology, , Volume: 277, Issue:6, 1999
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.Biochimica et biophysica acta, , Mar-04, Volume: 1417, Issue:2, 1999
A transfected cell model for the renal toxin transporter, rOCT2.Toxicological sciences : an official journal of the Society of Toxicology, , Volume: 47, Issue:2, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.Drug metabolism and disposition: the biological fate of chemicals, , Volume: 33, Issue:4, 2005
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.The Journal of biological chemistry, , Dec-04, Volume: 273, Issue:49, 1998
Transport of monoamine transmitters by the organic cation transporter type 2, OCT2.The Journal of biological chemistry, , Nov-20, Volume: 273, Issue:47, 1998
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Organic cation transporter-mediated renal secretion of ipratropium and tiotropium in rats and humans.Drug metabolism and disposition: the biological fate of chemicals, , Volume: 39, Issue:1, 2011
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Selective substrates for non-neuronal monoamine transporters.Molecular pharmacology, , Volume: 56, Issue:1, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.Biochimica et biophysica acta, , Mar-04, Volume: 1417, Issue:2, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.The Journal of pharmacology and experimental therapeutics, , Volume: 303, Issue:3, 2002
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.The Journal of pharmacology and experimental therapeutics, , Volume: 303, Issue:3, 2002
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
A transfected cell model for the renal toxin transporter, rOCT2.Toxicological sciences : an official journal of the Society of Toxicology, , Volume: 47, Issue:2, 1999