Page last updated: 2024-11-13
latilagascene f
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
latilagascene F: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 44588922 |
| CHEMBL ID | 519354 |
| MeSH ID | M0506714 |
Synonyms (2)
| Synonym |
|---|
| CHEMBL519354 |
| latilagascene f |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (7)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1377026 | Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by MTT assay | 2017 | Journal of natural products, 06-23, Volume: 80, Issue:6 | Terpenoids from Euphorbia soongarica and Their Multidrug Resistance Reversal Activity. |
| AID471323 | Cytotoxicity against human A2780 cells after 4 days by MTT assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9 | Chemical Constituents of the Roots of Euphorbia micractina. |
| AID471325 | Antiviral activity against HIV-1 NL4-3 expressing VSV-G envelope infected in human 293T cells assessed as inhibition of viral replication after 48 hrs by Luciferase reporter gene assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9 | Chemical Constituents of the Roots of Euphorbia micractina. |
| AID1377027 | Cytotoxicity against human KBv200 cells assessed as growth inhibition after 72 hrs by MTT assay | 2017 | Journal of natural products, 06-23, Volume: 80, Issue:6 | Terpenoids from Euphorbia soongarica and Their Multidrug Resistance Reversal Activity. |
| AID1377028 | Inhibition of P-gp in human KBv200 cells assessed as increase in intracellular rhodamine123 accumulation by measuring fluorescence activity ratio at 10 uM incubated for 4 hrs followed by rhodamine123 addition measured after 1 hr by flow cytometry | 2017 | Journal of natural products, 06-23, Volume: 80, Issue:6 | Terpenoids from Euphorbia soongarica and Their Multidrug Resistance Reversal Activity. |
| AID471324 | Inhibition of GST-tagged human PTP1B | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9 | Chemical Constituents of the Roots of Euphorbia micractina. |
| AID389396 | Lipophilicity, log P of the compound | 2008 | Bioorganic & medicinal chemistry, Oct-15, Volume: 16, Issue:20 | Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.56
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.56) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||