| Assay ID | Title | Year | Journal | Article |
|---|
| AID419744 | Inhibition of human recombinant MMP16 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID241672 | Inhibition of human matrix metalloprotease-14 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID732014 | Inhibition of MMP3 (unknown origin) | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Sulphonamides: Deserving class as MMP inhibitors? |
| AID419750 | Inhibition of MMP13-mediated collagen degradation in long term IL-1-alpha-stimulated pig articular cartilage explant culture assessed as hydroxyproline release at 10 uM | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID419742 | Inhibition of MMP13 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID419737 | Inhibition of MMP1 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID241639 | Inhibition of human matrix metalloprotease-2 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID242988 | Relative binding affinity for MMP2 and MMP7 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1863871 | Inhibition of MMP-2 (unknown origin) activity using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 4 hrs followed by substrate addition for 4 hrs by fluorimetric assay | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID419749 | Inhibition of MMP13-mediated collagen degradation in long term IL-1-alpha-stimulated pig articular cartilage explant culture assessed as hydroxyproline release | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID473229 | Inhibition of MMP1 by fluorometric assay | 2010 | Journal of medicinal chemistry, Mar-25, Volume: 53, Issue:6
| Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models. |
| AID732015 | Inhibition of MMP2 (unknown origin) | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Sulphonamides: Deserving class as MMP inhibitors? |
| AID419740 | Inhibition of MMP8 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID419735 | Inhibition of MMP13-mediated aggrecan breakdown in long term IL-1-alpha-stimulated pig articular cartilage explant culture assessed as GAG release at 1 uM | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID241641 | Inhibition of human matrix metalloprotease-7 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID473233 | Inhibition of human recombinant ADAM17 by fluorometric assay | 2010 | Journal of medicinal chemistry, Mar-25, Volume: 53, Issue:6
| Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models. |
| AID732016 | Inhibition of MMP13 (unknown origin) | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Sulphonamides: Deserving class as MMP inhibitors? |
| AID473232 | Inhibition of human recombinant MMP14 by fluorometric assay | 2010 | Journal of medicinal chemistry, Mar-25, Volume: 53, Issue:6
| Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models. |
| AID241643 | Inhibition of human matrix metalloprotease-9 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID473235 | Inhibition of ADAM-17-mediated sALCAM release in human A2774 cells at 10 uM by ELISA | 2010 | Journal of medicinal chemistry, Mar-25, Volume: 53, Issue:6
| Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models. |
| AID1863888 | Inhibition of MMP-9 (unknown origin) activity using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 4 hrs followed by substrate addition for 4 hrs by fluorimetric assay | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID419747 | Inhibition of MMP13-mediated collagen degradation by SDS-PAGE | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID349373 | Inhibition of MMP1 | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. |
| AID349379 | Inhibition of MMP9 | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. |
| AID419738 | Inhibition of MMP2 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID419741 | Inhibition of MMP9 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID419748 | Inhibition of MMP13-mediated aggrecan breakdown in long term IL-1-alpha-stimulated pig articular cartilage explant culture assessed as GAG release at 0.1 uM | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID419745 | Inhibition of TACE | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID241638 | Inhibition of human matrix metalloprotease-1 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1863887 | Inhibition of MMP-7 (unknown origin) activity using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 4 hrs followed by substrate addition for 4 hrs by fluorimetric assay | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID349374 | Inhibition of MMP2 | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. |
| AID731524 | Inhibition of MMP1 (unknown origin) | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Sulphonamides: Deserving class as MMP inhibitors? |
| AID473231 | Inhibition of MMP9 by fluorometric assay | 2010 | Journal of medicinal chemistry, Mar-25, Volume: 53, Issue:6
| Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models. |
| AID349378 | Inhibition of MMP7 | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. |
| AID419743 | Inhibition of human recombinant MMP14 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID731523 | Inhibition of MMP12 (unknown origin) | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Sulphonamides: Deserving class as MMP inhibitors? |
| AID473230 | Inhibition of MMP2 by fluorometric assay | 2010 | Journal of medicinal chemistry, Mar-25, Volume: 53, Issue:6
| Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models. |
| AID349375 | Inhibition of MMP3 | 2008 | Bioorganic & medicinal chemistry, Oct-01, Volume: 16, Issue:19
| Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. |
| AID732009 | Selectivity ratio of IC50 for MMP3 (unknown origin) to IC50 for MMP2 (unknown origin) | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Sulphonamides: Deserving class as MMP inhibitors? |
| AID419739 | Inhibition of MMP3 | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID419736 | Inhibition of MMP13-mediated aggrecan breakdown in long term IL-1-alpha-stimulated pig articular cartilage explant culture assessed as GAG release at 10 uM | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID241640 | Inhibition of human matrix metalloprotease-3 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1863872 | Inhibition of MMP-1 (unknown origin) activity using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 4 hrs followed by substrate addition for 4 hrs by fluorimetric assay | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID731526 | Inhibition of MMP9 (unknown origin) | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Sulphonamides: Deserving class as MMP inhibitors? |
| AID242986 | Relative binding affinity for MMP2 and MMP1 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID419746 | Inhibition of MMP1-mediated collagen degradation by SDS-PAGE | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15
| N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. |
| AID242990 | Relative binding affinity for MMP2 and MMP9 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1863873 | Inhibition of MMP-3 (unknown origin) activity using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 4 hrs followed by substrate addition for 4 hrs by fluorimetric assay | 2022 | Journal of medicinal chemistry, 08-25, Volume: 65, Issue:16
| Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery. |
| AID242987 | Relative binding affinity for MMP2 and MMP-3 as ratio of IC50 | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID493017 | Wombat Data for BeliefDocking | 2005 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 15, Issue:5
| N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. |
| AID1345417 | Human MMP2 (M10: Matrix metallopeptidase) | 2006 | Bioorganic & medicinal chemistry, Jun-15, Volume: 14, Issue:12
| Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |