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5-methylcytosine and Sensitivity and Specificity

5-methylcytosine has been researched along with Sensitivity and Specificity in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (23.08)18.2507
2000's3 (11.54)29.6817
2010's14 (53.85)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Cao, F; Guo, Z; He, Y; Hu, X; Li, A; Liu, H; Tu, K; Wei, A; Xia, L; Xie, D; Yuan, J; Zhang, J1
Gibas, P; Gordevičius, J; Kriukienė, E; Krjutškov, K; Kvederavičiūtė, K; Narmontė, M; Paluoja, P; Salumets, A; Tomkutė, V1
Chen, HY; Chen, L; He, C; He, XH; Hong, Y; Jing, HM; Li, F; Li, W; Lin, J; Liu, H; Liu, J; Pang, M; Qin, Y; Wang, J; Xiao, XB; Xu, N; Yan, C; Yang, P; Yang, ZR; Zhang, L; Zhang, WL; Zhu, HC1
Ebenstein, Y; Gilat, N; Michaeli, Y; Nifker, G; Shahal, T; Shwartz, A; Tabachnik, T; Torchinsky, D; Zirkin, S1
Carru, C; Ena, S; Fois, AG; Mangoni, AA; Pirina, P; Sotgia, S; Sotgiu, E; Zinellu, A; Zinellu, E1
Chung, TH; Jia, XY; Sun, X; Tan, D1
Chen, BJ; Dresser, K; Zhu, X1
He, N; Hou, P; Ji, M; Jin, W; Shi, B; Wu, K; Yang, Q1
Fu, B; Guo, G; Huang, R; Mao, W; Wang, J; Xing, X; Zhou, X1
Cai, W; Chen, B; Liu, Q; Mao, F; Sun, ZS; Wang, Z; Wu, H; Wu, J; Xie, Q; You, M1
Antony, HA; Bhat, V; Dhas, BB; Newton, B; Parija, SC1
Hall, AR; He, C; Zahid, OK; Zhao, BS1
Larson, GP; Lee, DH; Oates, N; Pfeifer, GP; Rivas, GE; Singh, P; Szabó, PE; Tran, DA1
Gu, Y; Hou, W; Li, F; Li, H; Li, Q; Lin, W; Song, Y; Sun, H; Yang, B; Zhang, F; Zhang, L1
Clark, TA; Dai, Q; He, C; Kislyuk, A; Korlach, J; Lu, XY; Song, CX; Turner, SW1
Acevedo, LG; Jelinek, MA; Sanz, A1
Claus, R; Dahl, E; Galm, O; Hielscher, T; Jost, E; Plass, C; Sonnet, M; Wilop, S1
Barciszewska, AM; Barciszewska, MZ; Gawronska, I; Keith, G; Nowak, S; Zukiel, R1
Födermayr, M; Lutz, D; Pammer, P; Pröll, J; Sonnleitner, M; Wechselberger, C; Zach, O1
Efremova, EJ; Limborska, SA; Myasnikov, VA; Potapov, VK; Prosnyak, MI; Sverdlov, ED; Veselovskaya, SI1
Bernardino, J; Bourgeois, CA; Dutrillaux, B; Gibaud, A; Malfoy, B; Niveleau, A; Veilleux, C1
Grigg, GW1
Allain, P; Boisdron-Celle, M; Gamelin, E; Larra, F; Robert, J; Turcant, A1
Clark, SJ; Melki, JR; Millar, DS; Paul, CL; Stirzaker, C; Warnecke, PM1
DePamphilis, ML; Rein, T; Zorbas, H1
Clark, SJ; Grunau, C; Rosenthal, A1

Reviews

3 review(s) available for 5-methylcytosine and Sensitivity and Specificity

ArticleYear
Novel DNA binding domain-based assays for detection of methylated and nonmethylated DNA.
    Epigenomics, 2011, Volume: 3, Issue:1

    Topics: 5-Methylcytosine; Biomarkers; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Primers; Humans; Immunoprecipitation; Polymerase Chain Reaction; Protein Interaction Domains and Motifs; Sensitivity and Specificity; Sulfites

2011
Sequencing 5-methylcytosine residues by the bisulphite method.
    DNA sequence : the journal of DNA sequencing and mapping, 1996, Volume: 6, Issue:4

    Topics: 5-Methylcytosine; Animals; Automation; Base Sequence; Cytosine; DNA; Indicators and Reagents; Nucleic Acid Denaturation; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Sulfites

1996
Identifying 5-methylcytosine and related modifications in DNA genomes.
    Nucleic acids research, 1998, May-15, Volume: 26, Issue:10

    Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Genome; Sensitivity and Specificity

1998

Other Studies

23 other study(ies) available for 5-methylcytosine and Sensitivity and Specificity

ArticleYear
Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer.
    Clinical epigenetics, 2020, 07-23, Volume: 12, Issue:1

    Topics: 5-Methylcytosine; Adenocarcinoma; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell-Free Nucleic Acids; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms; Reproducibility of Results; Sensitivity and Specificity

2020
Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing.
    Clinical epigenetics, 2020, 10-20, Volume: 12, Issue:1

    Topics: 5-Methylcytosine; Adult; Cell-Free Nucleic Acids; DNA Methylation; Down Syndrome; Epigenomics; Female; Fetal Diseases; Fetus; Genetic Testing; High-Throughput Nucleotide Sequencing; Humans; Male; Placenta; Pregnancy; Prenatal Diagnosis; Sensitivity and Specificity; Sequence Analysis, DNA; Trisomy

2020
5-Hydroxymethylcytosine profiles of cfDNA are highly predictive of R-CHOP treatment response in diffuse large B cell lymphoma patients.
    Clinical epigenetics, 2021, 02-11, Volume: 13, Issue:1

    Topics: 5-Methylcytosine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Cell-Free Nucleic Acids; Cohort Studies; Cyclophosphamide; DNA Demethylation; Doxorubicin; Female; Humans; Logistic Models; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Predictive Value of Tests; Prednisone; Rituximab; Sensitivity and Specificity; Vincristine

2021
Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers.
    Clinical epigenetics, 2017, Volume: 9

    Topics: 5-Methylcytosine; Colonic Neoplasms; DNA, Neoplasm; Epigenesis, Genetic; Hematologic Neoplasms; Humans; Microscopy, Fluorescence; Sensitivity and Specificity; Single Molecule Imaging

2017
Blood global DNA methylation is decreased in non-severe chronic obstructive pulmonary disease (COPD) patients.
    Pulmonary pharmacology & therapeutics, 2017, Volume: 46

    Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Case-Control Studies; DNA; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Sensitivity and Specificity; Severity of Illness Index

2017
Mirror Bisulfite Sequencing: A Method for Single-Base Resolution of Hydroxymethylcytosine.
    Analytical chemistry, 2018, 11-20, Volume: 90, Issue:22

    Topics: 5-Methylcytosine; Base Sequence; DNA; DNA-Cytosine Methylases; Gene Library; Glucosyltransferases; Humans; Reproducibility of Results; Sensitivity and Specificity; Sequence Analysis, DNA; Sulfites

2018
Loss of 5-hydroxymethylcytosine immunohistochemical expression is a useful diagnostic aid for distinguishing hepatocellular carcinoma in cytology fine needle aspiration specimens.
    Cytopathology : official journal of the British Society for Clinical Cytology, 2019, Volume: 30, Issue:5

    Topics: 5-Methylcytosine; Biopsy, Fine-Needle; Carcinoma, Hepatocellular; Cytodiagnosis; Diagnosis, Differential; Hepatocytes; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Predictive Value of Tests; ROC Curve; Sensitivity and Specificity

2019
Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients.
    Journal of biomedical nanotechnology, 2013, Volume: 9, Issue:9

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; China; Cytosine; Female; Humans; Incidence; Male; Middle Aged; Prognosis; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Stomach Neoplasms; Survival Analysis; Survival Rate

2013
A novel combined bisulfite UDG assay for selective 5-methylcytosine detection.
    Talanta, 2013, Dec-15, Volume: 117

    Topics: 5-Methylcytosine; Cytosine; DNA; DNA Cleavage; DNA Methylation; Electrophoresis, Polyacrylamide Gel; Enzyme Assays; Humans; Oligodeoxyribonucleotides; Sensitivity and Specificity; Sequence Analysis, DNA; Sodium Hydroxide; Solutions; Sulfites; Uracil; Uracil-DNA Glycosidase

2013
A Bayesian framework to identify methylcytosines from high-throughput bisulfite sequencing data.
    PLoS computational biology, 2014, Volume: 10, Issue:9

    Topics: 5-Methylcytosine; Algorithms; Bayes Theorem; High-Throughput Nucleotide Sequencing; Humans; Models, Genetic; Sensitivity and Specificity; Sequence Analysis, DNA; Sulfites

2014
Global DNA methylation in neonatal sepsis.
    Indian journal of pediatrics, 2015, Volume: 82, Issue:4

    Topics: 5-Methylcytosine; Biomarkers; Birth Weight; DNA Methylation; Epigenesis, Genetic; Female; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, Diseases; Prognosis; Reproducibility of Results; Sensitivity and Specificity; Sepsis

2015
Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores.
    Scientific reports, 2016, 07-07, Volume: 6

    Topics: 5-Methylcytosine; Animals; Biotinylation; DNA; Epigenesis, Genetic; Genomics; Mice; Nanopores; Oligonucleotides; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Ultrasonics

2016
MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation.
    Epigenetics, 2011, Volume: 6, Issue:2

    Topics: 5-Methylcytosine; Alleles; Animals; Chromosome Duplication; CpG Islands; Cytosine; DNA Methylation; Genomic Imprinting; Kidney; Liver; Mice; Sensitivity and Specificity; Sequence Analysis, DNA

2011
Evaluation of global DNA hypomethylation in human prostate cancer and prostatic intraepithelial neoplasm tissues by immunohistochemistry.
    Urologic oncology, 2013, Volume: 31, Issue:5

    Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Disease Progression; DNA Methylation; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasm Grading; Prognosis; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Reproducibility of Results; Sensitivity and Specificity

2013
Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine.
    Nature methods, 2011, Nov-20, Volume: 9, Issue:1

    Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; Sensitivity and Specificity; Sequence Analysis, DNA

2011
A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR.
    Epigenetics, 2012, Volume: 7, Issue:7

    Topics: 5-Methylcytosine; 5' Untranslated Regions; Aged; Aged, 80 and over; DNA Methylation; Female; High-Throughput Nucleotide Sequencing; Humans; Inhibitor of Differentiation Proteins; Leukemia, Myeloid, Acute; Male; Mass Spectrometry; Middle Aged; Polymerase Chain Reaction; Sensitivity and Specificity; Sequence Analysis, DNA; Young Adult

2012
A simple epigenetic method for the diagnosis and classification of brain tumors.
    Molecular cancer research : MCR, 2004, Volume: 2, Issue:3

    Topics: 5-Methylcytosine; Adult; Aged; Brain Neoplasms; Chromatography, Thin Layer; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Sensitivity and Specificity

2004
Ultra-sensitive immunodetection of 5'methyl cytosine for DNA methylation analysis on oligonucleotide microarrays.
    DNA research : an international journal for rapid publication of reports on genes and genomes, 2006, Feb-28, Volume: 13, Issue:1

    Topics: 5-Methylcytosine; Antibody Specificity; DNA Methylation; Feasibility Studies; HL-60 Cells; Humans; Models, Biological; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Sensitivity and Specificity

2006
Substitution of 2-aminoadenine and 5-methylcytosine for adenine and cytosine in hybridization probes increases the sensitivity of DNA fingerprinting.
    Genomics, 1994, Volume: 21, Issue:3

    Topics: 2-Aminopurine; 5-Methylcytosine; Adenine; Base Sequence; Blotting, Southern; Cytosine; DNA; DNA Fingerprinting; DNA Primers; Humans; Molecular Sequence Data; Oligonucleotide Probes; Sensitivity and Specificity

1994
[Changes in methylation of tumor cells: a new in situ quantitative approach on interphase nuclei and chromosomes].
    Bulletin du cancer, 1995, Volume: 82, Issue:11

    Topics: 5-Methylcytosine; Cell Nucleus; Chromosome Banding; Chromosomes, Human; Cytosine; DNA; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Interphase; Metaphase; Methylation; Sensitivity and Specificity; Tumor Cells, Cultured

1995
Rapid and sensitive high-performance liquid chromatographic analysis of halogenopyrimidines in plasma.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Aug-01, Volume: 695, Issue:2

    Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Bromouracil; Chromatography, High Pressure Liquid; Cytosine; Flucytosine; Fluorouracil; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Uracil

1997
Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA.
    Nucleic acids research, 1997, Nov-01, Volume: 25, Issue:21

    Topics: 5-Methylcytosine; Animals; Base Composition; Cell Line; Cytosine; DNA; DNA Methylation; DNA Primers; Genes, Retinoblastoma; Humans; Mice; Polymerase Chain Reaction; Sensitivity and Specificity; Sulfites

1997
Bisulfite genomic sequencing: systematic investigation of critical experimental parameters.
    Nucleic acids research, 2001, Jul-01, Volume: 29, Issue:13

    Topics: 5-Methylcytosine; Amination; Bacteriophage M13; Base Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Cytosine; DNA; DNA Methylation; DNA Primers; DNA, Single-Stranded; DNA, Viral; Genome; Molecular Sequence Data; Nucleic Acid Denaturation; Plasmids; Polymerase Chain Reaction; Sensitivity and Specificity; Sequence Analysis, DNA; Sulfites; Temperature; Templates, Genetic; Uracil

2001