thiophenes has been researched along with Sensitivity and Specificity in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (4.38) | 18.2507 |
| 2000's | 69 (50.36) | 29.6817 |
| 2010's | 59 (43.07) | 24.3611 |
| 2020's | 3 (2.19) | 2.80 |
| Authors | Studies |
|---|---|
| Bahmany, S; Danser, AHJ; Hitzerd, E; Koch, BCP; van de Velde, D; van Domburg, B; Versmissen, J | 1 |
| Nadella, PN; Nadh Ratnakaram, V; Navuluri, S | 1 |
| Babapoor, A; Bahrani, S; Behbudi, G; Chiang, WH; Gholami, A; Hashemi, SA; Lai, CW; Mousavi, SM; Omidifar, N; Yousefi, K | 1 |
| Ali, MS; Carbonell, C; Martinez-Laguna, D; Prieto-Alhambra, D; Reyes, C; Soria-Castro, A; Tebe, C | 1 |
| Han, J; Li, Y; Liu, W; Sha, C; Shao, X; Wang, L; Yang, H; Yu, F; Zhao, F | 1 |
| Berto, M; Biscarini, F; Bortolotti, CA; Di Lauro, M; Giordani, M; Zoli, M | 1 |
| Haglund, C; Hermunen, K; Lantto, E; Österlund, P; Poussa, T | 1 |
| Chow, MSS; Hao, J; Ramirez, A; Wang, Z; Xie, C | 1 |
| Livingston, KE; Mahoney, JP; Manglik, A; Sunahara, RK; Traynor, JR | 1 |
| Feng, J; Hu, R; Li, S; Li, Y; Wang, S; Xiong, L; Yang, G | 1 |
| Baek, HM; Chae, JW; Kang, HI; Kim, SK; Kwon, KI | 1 |
| Hu, C; Hu, Y; Qiu, N; Shangguan, S; Wang, W; Zhang, L | 1 |
| Hu, C; Hu, Y; Lv, D; Qiu, N; Wang, W; Zhang, L | 1 |
| Abtan, J; Barthélémy, O; Beygui, F; Brugier, D; Collet, JP; Kerneis, M; Montalescot, G; O'Connor, SA; Silvain, J; Vignalou, JB | 1 |
| Han, J; Hu, L; Li, H; Liu, Y; Pei, M; Zhang, G | 1 |
| Bordignon-Luiz, MT; Burin, VM; de Revel, G; Marchand, S | 1 |
| Adelmeijer, J; Arshad, F; Blokzijl, H; Lisman, T; Porte, RJ; Potze, W; van den Berg, AP | 1 |
| Bagot, CN; Hickman, G; Lawrence, C; McGurk, M; Rodgers, R; Tait, RC | 1 |
| Dhillon, K; Dovlatova, N; Fox, SC; Glenn, JR; Heptinstall, S; White, AE | 1 |
| Jiang, Y; Yu, J; Zeng, H; Zeng, X | 1 |
| Angiolillo, DJ; Baker, BA; Heiselman, DE; Jakubowski, JA; Li, W; Price, MJ | 1 |
| Hua, K; Ji, H; Li, TT; Liu, L; Sheng, X; Tan, JN; Wang, LN; Wei, B; Zhang, YH | 1 |
| Cybulski, M; Maruszak, W | 1 |
| Liu, H; Ma, F; Rehman, A; Zeng, X; Zhang, J; Zhu, S | 1 |
| Hogg, K; Weitz, JI; Yeh, CH | 1 |
| Benincori, T; D'Souza, F; Huynh, TP; Kutner, W; Sannicolò, F; Sosnowska, M; Srebnik, S; Wojnarowicz, A | 1 |
| Bijzet, J; Hammarström, P; Hazenberg, BP; Nilsson, KP; Sjölander, D | 1 |
| Dias, JD; Doorneweerd, DD; Norem, K; Omert, LA; Popovsky, MA; Thurer, RL | 1 |
| Guler, M; Kivrak, A; Turkoglu, V | 1 |
| Kumar Singh, A; Singh, M | 1 |
| Dong, D; Li, Z; Sun, H; Wu, B; Wu, Z; Xue, Y | 1 |
| Chung, MH; Lee, AS; Lee, CK; Lee, SS; Liu, MW; Tsai, PI | 1 |
| Dai, Y; Fan, L; Kan, X; Li, X; Lu, X | 1 |
| Fraboni, B; Gualandi, I; Mariani, F; Marzocchi, M; Scavetta, E; Tonelli, D | 1 |
| Al-Shihry, SS; Arafa, RK; El-Sayed, WM; Ismail, MA; Youssef, MM | 1 |
| Acquaviva, C; Braendlein, M; Ferro, M; Lopresti, A; Malliaras, GG; Mamessier, E; Owens, RM; Pappa, AM | 1 |
| Costa, SP; Esteves, CI; Raposo, MM | 1 |
| Loew, LM; Wei, M; Xie, A; Yan, P | 1 |
| Ahn, KH; Kim, DS | 1 |
| Rohde, G | 1 |
| Peng, H; Soeller, C; Spires, JB; Travas-Sejdic, J; Williams, DE; Wright, BE | 1 |
| Guan, H; He, Z; Zhou, P; Zhou, X | 1 |
| Gooley, PR; Honeyman, JE; Iseli, TJ; Jorgensen, SB; Kemp, BE; Koay, A; Oakhill, JS; Scott, JW; Stapleton, D; Steinberg, GR; van Denderen, BJ | 1 |
| Huang, X; Li, Y; Wang, L; Wang, P | 1 |
| Chitta, R; D'Souza, F; Kutner, W; Pietrzyk, A; Suriyanarayanan, S | 1 |
| Herrera-León, L; Jiménez Pajares, MS; Molina Moreno, T; Pozuelo-Díaz, R; Saiz Vega, P; Valverde Cobacho, A | 1 |
| Bandel, TJ; Bauer, KA; Benson, A; Berkowitz, SD; Cushner, FD; Davidson, BL; Fisher, WD; Gent, M; Kwong, LM; Lassen, MR; Lotke, PA; Misselwitz, F; Turpie, AG | 1 |
| Strege, MA | 1 |
| Cheng, G; Peng, WX; Song, J; Tang, J; Zhao, RK | 1 |
| Cho, MS; Choe, WS; Lee, Y; Lin, M | 1 |
| Andre, M; Bentivoglio, G; Laus, G; Schottenberger, H | 1 |
| Bergeron, MG; Boissinot, M; Boudreau, D; Corbeil, G; Doré, K; Ho, HA; Leclerc, M | 1 |
| Bhinge, JR; Kumria, R; Sinha, VR | 1 |
| Price, WS; Torres, AM; Zheng, G | 1 |
| Aguzzi, A; Aslund, A; Fransson, S; Ikenberg, K; Konradsson, P; Moch, H; Nilsson, KP; Röcken, C | 1 |
| Duckett, J; Jacklin, P; Renganathan, A | 1 |
| Ananthapavan, J; Diamantopoulos, A; Forster, F; Lees, M; McDonald, H; Wells, PS | 1 |
| Fang, Y; Li, JY; Liu, K; Yao, C; You, XY; Zhou, Y | 1 |
| Kourti, PV; Samanidou, VF | 1 |
| Dakanali, M; Haidekker, MA; Nipper, ME; Theodorakis, E | 1 |
| Aboul-Enein, HY; Al-Zoman, NZ; Asiri, YA; Hefnawy, MM; Mostafa, GA | 1 |
| Hande, A; Kumar Jha, C; Lukram, O; Parmar, S; Tomar, KS; Zarapkar, M | 1 |
| Noh, HB; Rahman, MA; Shim, YB; Yang, JE | 1 |
| Cho, SH; Duin, EC; Hong, JW; Jambovane, S; Kim, SK; Yun, JY | 1 |
| Chandra, P; Kim, DM; Koh, WC; Shim, YB | 1 |
| Jin, QR; Kim, CY; Kim, DG; Lee, GW; Lee, JH; Lee, KR; Lim, H; Noh, HJ; Park, DH; Woo, YA | 1 |
| Ait-Mokhtar, O; Barnay, P; Bonello, L; Bonello, R; Cabassome, E; Camilleri, E; Camoin-Jau, L; Cheneau, E; Collet, F; de Labriolle, A; Dignat-George, F; Jouve, B; Maillard, L; Mancini, J; Paganelli, F; Pansieri, M; Peyre, JP; Rossi, P; Wittenberg, O | 1 |
| Alberio, L; Angelillo-Scherrer, A; Asmis, LM; Korte, W; Mendez, A; Reber, G; Seifert, B; Stricker, H; Tsakiris, DA; Wuillemin, WA | 1 |
| Bergeron, MG; Leclerc, M; Lepage, PH; Peytavi, R | 1 |
| Giese, C; Harenberg, J; Krämer, R; Marx, S; Weiss, C | 1 |
| Hosokawa, R; Iida, T; Inagaki, T; Inenaga, K; Ono, K; Wakasugi-Sato, N | 1 |
| Ahmad, M; Ghani, SA; Hashim, N; Isa, IM; Mustafar, S | 1 |
| Contant, G; Gourmelin, Y; Guinet, C; Le Flem, L; Martinoli, JL; Perzborn, E; Rohde, G; Samama, MM; Spiro, TE | 1 |
| Buonarati, MH; Hop, CE; Jones, SA; Liu, L; Murakami, SC; Shin, YG; Wong, H | 1 |
| Funatsu, T; Iwatsuki, Y; Kaku, S | 1 |
| Buszewski, B; Jackowski, M; Szeliga, J; Szultka, M | 1 |
| Rao, SS; Reddy, AM; Sharma, N | 1 |
| Liedberg, B; Mailepessov, D; Sheng, CW; Shochat, SG; Xueqi, DC; Yildiz, UH | 1 |
| Bikram K C, C; D'Souza, F; Huynh, TP; Kutner, W; Noworyta, KR; Pietrzyk-Le, A; Sharma, PS; Sobczak, JW | 1 |
| Boyd, KG; Burgess, JG; Díaz, MP; Grigson, SJ | 1 |
| Becchi, M; García, CL; Grenier-Loustalot, MF; Païsse, O; Szymanskit, R | 1 |
| Kelliher, P; Kelly, JP; Leonard, BE; Sánchez, C | 1 |
| Buhr, HJ; Foitzik, T; Hines, OJ; Hotz, B; Hotz, HG; Reber, HA | 1 |
| Maruhashi, K; Noda, K; Watanabe, K | 1 |
| Chaubey, A; Kaneto, K; Malhotra, BD; Singhal, R; Takashima, W | 1 |
| Carrillo-Muñoz, AJ; Fernandez-Torres, B; Guarro, J | 1 |
| Park, DS; Rahman, MA; Shim, YB | 1 |
| Bieck, PR; Black, BK; Bymaster, FP; Garland, EM; Gonzales, C; Loghin, C; Potter, WZ; Robertson, D; Vincent, S | 1 |
| Bizzotto, D; Chung, E; Shepherd, JL; Wolf, MO | 1 |
| Hirai, K; Kurono, M; Morisaki, F; Tomioka, H | 1 |
| Davis, JM; Liu, S | 1 |
| Chu, H; Kensler, TW; Muñoz, A | 1 |
| Li, C; Numata, M; Shinkai, S; Takeuchi, M | 1 |
| Chu, H; Cole, SR; Nie, L | 1 |
| Basov, DN; Di Ventra, M; Heeger, AJ; Li, ZQ; Martin, MC; Moses, D; Sai, N; Wang, GM | 1 |
| Che, Y; Ji, H; Ma, W; Zang, L; Zhao, J | 1 |
| Dunsch, L; Hartmann, H; Rapta, P; Rohde, D; Zeika, O | 1 |
| Alonso, RM; Ferreirós, N; Iriarte, G; Jiménez, RM; Ortíz, E | 1 |
| Fischer, G; Lausecker, B | 1 |
| Jia, WL; Li, TH; Wang, HS; Xu, HY | 1 |
| Kou, Y; Liu, K; Liu, Y; Ruan, J; Xu, Y; Xue, M; Zhang, Z | 1 |
| Concistré, M; De Lorenzo, L; De Luca, G; Longeri, M; Pileio, G; Raos, G | 1 |
| Berlin, A; Casado, J; Grimoldi, S; Hernandez, V; López Navarrete, JT; Ortiz, RP; Osuna, RM; Ruiz Delgado, MC; Zotti, G | 1 |
| Bilge, A; Burrows, HD; Farrell, T; Forster, M; Pina, J; Scherf, U; Seixas de Melo, J | 1 |
| Cottam, HB; Endo, T; Enzler, T; Fukuda, T; James, DF; Karin, M; Kipps, TJ; Nishio, M | 1 |
| Dholakia, GR; Facchetti, A; Marks, TJ; Meyyappan, M | 1 |
| Arya, SK; Datta, M; Kaneto, K; Malhotra, BD; Pandey, MK; Singh, SP; Solanki, PR | 1 |
| Jäkle, F; Rheingold, AL; Sundararaman, A; Venkatasubbaiah, K; Victor, M; Zakharov, LN | 1 |
| Bao, Z; DeLongchamp, DM; Fischer, DA; Jung, Y; Lin, EK; Ling, MM; Roberts, ME | 1 |
| Iyoda, M; Kuwatani, Y; Miyasaka, H; Nakao, K; Nishimura, M; Nishinaga, T; Tamachi, T | 1 |
| Barrett, EM; Bradley, DD; Das, R; deMello, AJ; deMello, JC; Hofmann, O; Wang, X | 1 |
| Balenkova, ES; Hernandez, V; Navarrete, JT; Nenajdenko, VG; Ortiz, RP; Osuna, RM; Sumerin, VV; Vercelli, B; Zotti, G | 1 |
| Forster, M; Hania, PR; Scheblykin, IG; Thomsson, D | 1 |
| Abd El-Aty, AM; Cho, SK; Choi, JH; Kang, CA; Khay, S; Kim, SJ; Park, BJ; Park, YS; Shim, JH | 1 |
| Beyer, J; Eriksson, BI; Halbritter, K; Kakkar, AK; Kälebo, P; Misselwitz, F; Schellong, SM; Turpie, AG | 1 |
| Kafafi, ZH; Kushto, GP; Mäkinen, AJ; Watkins, NJ | 1 |
| Amore, M; Cazzolla, R; Mandrioli, R; Mercolini, L; Raggi, MA | 1 |
| Balamurugan, A; Chen, SM | 1 |
| Chattopadhyay, A; Panda, BR | 1 |
| Ram, CV; Rudmann, MA | 1 |
| Fang, B; Jiang, X; Jiao, S; Li, M; Qu, Y | 1 |
| Dinh-Xuan, AT; Hoeper, MM | 1 |
| Aurbach, D; Demadrille, R; Fisyuk, A; Levi, MD; Pomerantz, Z; Pron, A; Salitra, G; Zaban, A | 1 |
| Gu, H; Swager, TM; Wang, F | 1 |
| Anil, TM; Mohan, CV; Palaksha, KJ; Patil, P; Patil, R; Shankarl, KM; Sripada, A | 1 |
| Au, T; Constanzer, M; Kasper, M; Matuszewski, B; Woolf, EJ | 1 |
| Cormann, P; Macherey, HJ; Petersen, KU; Sprakties, G; Winterhager, JM | 1 |
| Chavez, CM; Constanzer, ML; Matuszewski, BK | 1 |
| Forghani, F; Keen, S; Ouellet, M; Percival, MD; Tagari, P | 1 |
| Bohnenstengel, F; Hofmann, U; Kroemer, HK; Ritter, CA; Sperker, B | 1 |
| Adamson, PC; Balis, FM; Godwin, KS; McCully, C; Widemann, BC | 1 |
| Karger, BL; Kautz, RA; Tim, RC | 1 |
| Duarte, GF; Keijzer-Wolters, A; Smit, E; van Elsas, JD | 1 |
| Bennett, JL; Bennink, M; Crowell, J; Dimitrov, NV; Gardiner, J; Hawk, E; Leece, CM; Nashawaty, M; Seymour, E; Tompkins, ER | 1 |
| Curtin, NJ; Errington, J; Lu, X; Lunec, J; Newell, DR | 1 |
| Auberval, M; Baron, R; Bodary, S; Breipohl, G; Carniato, D; Doucet, B; Gadek, TR; Gaillard, M; Gourvest, J; Knolle, J; Peyman, A; Ruxer, J; Scheunemann, K; Stilz, HU; Wehner, V; Will, DW | 1 |
| Asada, M; Kondo, K; Maruyama, T; Nakai, H; Ohuchida, S; Sakata, K; Seki, A; Shinagawa, Y; Shiraishi, T; Toda, M; Yoshida, H | 1 |
4 review(s) available for thiophenes and Sensitivity and Specificity
| Article | Year |
|---|---|
Recent Advancements in Polythiophene-Based Materials and their Biomedical, Geno Sensor and DNA Detection.
Topics: Anti-HIV Agents; Biocompatible Materials; Biosensing Techniques; Coated Materials, Biocompatible; DNA; Electrochemical Techniques; Electrodes; Microscopy, Atomic Force; Polymers; Sensitivity and Specificity; Thiophenes | 2021 |
Overview of the new oral anticoagulants: opportunities and challenges.
Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dabigatran; Dose-Response Relationship, Drug; Drug Administration Schedule; Factor Xa Inhibitors; Female; Humans; Male; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Sensitivity and Specificity; Stroke; Thiazoles; Thiophenes; Thromboembolism; Warfarin | 2015 |
Cost-effectiveness of rivaroxaban versus enoxaparin for the prevention of postsurgical venous thromboembolism in Canada.
Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Canada; Cost-Benefit Analysis; Enoxaparin; Follow-Up Studies; Humans; Morpholines; Postoperative Complications; Quality of Life; Rivaroxaban; Sensitivity and Specificity; Thiophenes; Venous Thromboembolism | 2010 |
Unique dual mechanism of action of eprosartan: effects on systolic blood pressure, pulse pressure, risk of stroke and cognitive decline.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Cognition Disorders; Female; Humans; Hypertension; Imidazoles; Male; Sensitivity and Specificity; Severity of Illness Index; Stroke; Survival Analysis; Systole; Thiophenes; Treatment Outcome | 2007 |
11 trial(s) available for thiophenes and Sensitivity and Specificity
| Article | Year |
|---|---|
Can carcinoembryonic antigen replace computed tomography in response evaluation of metastatic colorectal cancer?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Quinazolines; ROC Curve; Sensitivity and Specificity; Thiophenes; Tomography, X-Ray Computed | 2018 |
Detecting a thienopyridine effect by platelet reactivity assessment and its implications for risk stratification.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Point-of-Care Systems; Prasugrel Hydrochloride; Pyridines; Receptors, Purinergic P2Y12; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial.
Topics: Administration, Oral; Aged; Analysis of Variance; Anticoagulants; Arthroplasty, Replacement, Knee; Double-Blind Method; Enoxaparin; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Morpholines; Phlebography; Risk Reduction Behavior; Rivaroxaban; Sensitivity and Specificity; Thiophenes; Treatment Outcome; Venous Thrombosis | 2009 |
Pharmacokinetics of duloxetine hydrochloride enteric-coated tablets in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Area Under Curve; China; Chromatography, Liquid; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Tablets, Enteric-Coated; Tandem Mass Spectrometry; Thiophenes; Young Adult | 2009 |
Cost-effectiveness of rivaroxaban versus enoxaparin for the prevention of postsurgical venous thromboembolism in Canada.
Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Canada; Cost-Benefit Analysis; Enoxaparin; Follow-Up Studies; Humans; Morpholines; Postoperative Complications; Quality of Life; Rivaroxaban; Sensitivity and Specificity; Thiophenes; Venous Thromboembolism | 2010 |
High on-treatment platelet reactivity after prasugrel loading dose and cardiovascular events after percutaneous coronary intervention in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Blood Platelets; Coronary Thrombosis; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Phosphoproteins; Piperazines; Prasugrel Hydrochloride; Predictive Value of Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; ROC Curve; Sensitivity and Specificity; Stents; Thiophenes | 2011 |
Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of GDC-0834 and its metabolite in human plasma using semi-automated 96-well protein precipitation.
Topics: Chemical Precipitation; Chromatography, Liquid; Double-Blind Method; Drug Stability; Humans; Linear Models; Pyrimidinones; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Thiophenes | 2012 |
Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Heart Rate; Humans; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Posture; Radioligand Assay; Sensitivity and Specificity; Symporters; Systole; Thiophenes; Tyramine | 2004 |
Assessing the effect of interventions in the context of mixture distributions with detection limits.
Topics: Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Carcinoma, Hepatocellular; China; Double-Blind Method; Humans; Likelihood Functions; Liver Neoplasms; Models, Statistical; Placebos; Pyrazines; Sensitivity and Specificity; Thiones; Thiophenes | 2005 |
Ultrasound screening for asymptomatic deep vein thrombosis after major orthopaedic surgery: the VENUS study.
Topics: Anticoagulants; Enoxaparin; Hip Prosthesis; Humans; Knee Prosthesis; Morpholines; Orthopedic Procedures; Phlebography; Postoperative Complications; Rivaroxaban; Sensitivity and Specificity; Thiophenes; Ultrasonography; Venous Thrombosis | 2007 |
Oltipraz concentrations in plasma, buccal mucosa cells, and lipids: pharmacological studies.
Topics: Administration, Oral; Adult; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lipid Metabolism; Lung Neoplasms; Male; Middle Aged; Mouth Mucosa; Probability; Pyrazines; Risk Assessment; Sensitivity and Specificity; Smoking; Statistics, Nonparametric; Thiones; Thiophenes; Tissue Distribution | 2001 |
123 other study(ies) available for thiophenes and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous quantification of ambrisentan, macitentan and sitaxentan in human plasma using UPLC-MS/MS.
Topics: Antihypertensive Agents; Chromatography, High Pressure Liquid; Humans; Isoxazoles; Linear Models; Phenylpropionates; Pyridazines; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Tandem Mass Spectrometry; Thiophenes | 2020 |
QbD-Based UPLC Method for Quantification of Brexpiprazole in Presence of Impurities and Application to In Vitro Dissolution.
Topics: Chromatography, High Pressure Liquid; Drug Contamination; Linear Models; Quinolones; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2021 |
One and two-year persistence with different anti-osteoporosis medications: a retrospective cohort study.
Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Databases, Factual; Denosumab; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Medication Adherence; Middle Aged; Osteoporosis, Postmenopausal; Retrospective Studies; Sensitivity and Specificity; Social Class; Spain; Teriparatide; Thiophenes | 2017 |
Validated LC-MS/MS method for the simultaneous determination of rotigotine and its prodrug in rat plasma and an application to pharmacokinetics and biological conversion in vitro.
Topics: Animals; Chromatography, Liquid; Liquid-Liquid Extraction; Male; Plasma; Prodrugs; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tetrahydronaphthalenes; Thiophenes | 2017 |
Specific Dopamine Sensing Based on Short-Term Plasticity Behavior of a Whole Organic Artificial Synapse.
Topics: Ascorbic Acid; Biomimetic Materials; Dimethylpolysiloxanes; Dopamine; Electrochemical Techniques; Electrodes; Limit of Detection; Polystyrenes; Sensitivity and Specificity; Synapses; Thiophenes; Uric Acid | 2017 |
A simple and sensitive HPLC-MS/MS method for quantification of eggmanone in rat plasma and its application to pharmacokinetics.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Female; Male; Phosphodiesterase 4 Inhibitors; Plasma; Pyrimidinones; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Thiophenes | 2018 |
Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor.
Topics: Allosteric Regulation; Allosteric Site; Biosensing Techniques; Biotin; Humans; Interferometry; Ligands; Loperamide; Methadone; Protein Binding; Receptors, Opioid, mu; Sensitivity and Specificity; Single-Domain Antibodies; Small Molecule Libraries; Solutions; Streptavidin; Thiophenes; Urea | 2018 |
Sensing in 15 s for aqueous fluoride anion by water-insoluble fluorescent probe incorporating hydrogel.
Topics: Benzothiazoles; Fluorescent Dyes; Fluorides; Hydrogels; Sensitivity and Specificity; Solutions; Spectrometry, Fluorescence; Thiophenes; Time Factors; Water | 2013 |
Quantitative determination of duloxetine and its metabolite in rat plasma by HPLC-MS/MS.
Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Drug Stability; Duloxetine Hydrochloride; Methanol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Thiophenes | 2013 |
Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction. Part 1.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Protein Binding; Proto-Oncogene Proteins c-mdm2; Sensitivity and Specificity; Structure-Activity Relationship; Thiophenes; Tumor Suppressor Protein p53 | 2013 |
Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction. Part 2.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Protein Binding; Proto-Oncogene Proteins c-mdm2; Sensitivity and Specificity; Structure-Activity Relationship; Thiophenes; Tumor Suppressor Protein p53 | 2013 |
Identification of poor response to P2Y12 inhibitors in ACS patients with a new ELISA-based vasodilator-associated stimulated phosphoprotein (VASP) phosphorylation assay.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Cell Adhesion Molecules; Cell Separation; Clopidogrel; Enzyme-Linked Immunosorbent Assay; Feasibility Studies; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Piperazines; Platelet Function Tests; Prasugrel Hydrochloride; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Thiophenes; Ticlopidine | 2013 |
A new fluorescence "off-on" chemodosimeter for L-cysteine based on water-soluble polythiophene.
Topics: Biological Assay; Chlorides; Cysteine; Fluorescent Dyes; Gold Compounds; Humans; Piperidines; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes | 2013 |
Development and validation of method for heterocyclic compounds in wine: optimization of HS-SPME conditions applying a response surface methodology.
Topics: Factor Analysis, Statistical; Furans; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Maillard Reaction; Pyrazines; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Microextraction; Temperature; Thiazoles; Thiophenes; Wine | 2013 |
Routine coagulation assays underestimate levels of antithrombin-dependent drugs but not of direct anticoagulant drugs in plasma from patients with cirrhosis.
Topics: Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation; Blood Coagulation Tests; Dabigatran; Diagnostic Tests, Routine; Drug Monitoring; Factor Xa Inhibitors; False Negative Reactions; Female; Fondaparinux; Heparin; Heparin, Low-Molecular-Weight; Humans; Liver Cirrhosis; Male; Middle Aged; Morpholines; Polysaccharides; Prothrombin; Rivaroxaban; Sensitivity and Specificity; Thiophenes; Thrombophilia | 2013 |
Correlating prothrombin time with plasma rivaroxaban level.
Topics: Blood Coagulation; Calibration; Factor Xa Inhibitors; Humans; Morpholines; Partial Thromboplastin Time; Patient Compliance; Prothrombin Time; Rivaroxaban; Sensitivity and Specificity; Thiophenes | 2013 |
'VASPFix' for measurement of VASP phosphorylation in platelets and for monitoring effects of P2Y12 antagonists.
Topics: Adenosine; Adenosine Diphosphate; Alprostadil; Biomarkers, Pharmacological; Blood Platelets; Bucladesine; Cell Adhesion Molecules; Cells, Cultured; Clopidogrel; Cyclic AMP; Humans; Iloprost; Microfilament Proteins; Phosphoproteins; Phosphorylation; Piperazines; Platelet Aggregation; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Reproducibility of Results; Sensitivity and Specificity; Thiophenes; Thrombophilia; Ticlopidine | 2014 |
Complex thiolated mannose/quinone film modified on EQCM/Au electrode for recognizing specific carbohydrate-proteins.
Topics: Benzoquinones; Biosensing Techniques; Conductometry; Equipment Design; Equipment Failure Analysis; Mannose; Micro-Electrical-Mechanical Systems; Plant Lectins; Polymers; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2014 |
An HPLC method for the quantitation of 3-pentylbenzo[c]thiophen-1(3H)-one in dog plasma and its application to a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Drug Stability; Female; Linear Models; Male; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2014 |
Simultaneous determination of the counter ion and possible impurity from the synthetic route in the pharmaceutical substance prasugrel hydrochloride.
Topics: Acetic Acid; Drug Contamination; Hydrochloric Acid; Ions; Molecular Structure; Piperazines; Prasugrel Hydrochloride; Sensitivity and Specificity; Technology, Pharmaceutical; Thiophenes | 2015 |
Glycosylation of quinone-fused polythiophene for reagentless and label-free detection of E. coli.
Topics: Biosensing Techniques; Concanavalin A; Electrochemical Techniques; Escherichia coli; Escherichia coli Infections; Glycosylation; Humans; Mannose; Polymers; Quartz Crystal Microbalance Techniques; Quinones; Sensitivity and Specificity; Thiophenes | 2015 |
Cytosine derivatized bis(2,2'-bithienyl)methane molecularly imprinted polymer for selective recognition of 6-thioguanine, an antitumor drug.
Topics: Antineoplastic Agents; Conductometry; Cytosine; Equipment Design; Equipment Failure Analysis; Molecular Imprinting; Reproducibility of Results; Sensitivity and Specificity; Surface Properties; Thioguanine; Thiophenes | 2015 |
Sensitive and rapid assessment of amyloid by oligothiophene fluorescence in subcutaneous fat tissue.
Topics: Adult; Aged; Amyloid; Amyloidogenic Proteins; Amyloidosis; Case-Control Studies; Congo Red; Female; Fluorescent Dyes; Humans; Male; Middle Aged; Sensitivity and Specificity; Spectrometry, Fluorescence; Staining and Labeling; Subcutaneous Fat; Thiophenes; Young Adult | 2015 |
Use of Thromboelastography (TEG) for Detection of New Oral Anticoagulants.
Topics: Adolescent; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Dabigatran; Factor Xa Inhibitors; Humans; Morpholines; Pyrazoles; Pyridones; Rivaroxaban; Sensitivity and Specificity; Thiophenes; Thrombelastography; Venous Thromboembolism; Young Adult | 2015 |
A novel glucose oxidase biosensor based on poly([2,2';5',2″]-terthiophene-3'-carbaldehyde) modified electrode.
Topics: Aldehydes; Biosensing Techniques; Blood Glucose; Electrodes; Enzymes, Immobilized; Glucose Oxidase; Humans; Kinetics; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2015 |
QCM sensing of melphalan via electropolymerized molecularly imprinted polythiophene films.
Topics: Acetates; Electroplating; Equipment Design; Equipment Failure Analysis; Melphalan; Membranes, Artificial; Micro-Electrical-Mechanical Systems; Molecular Imprinting; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2015 |
A validated ultra-performance liquid chromatography-tandem mass spectrometry method to identify the pharmacokinetics of SR8278 in normal and streptozotocin-induced diabetic rats.
Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Isoquinolines; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Thiophenes | 2016 |
Enhanced Signal and Quantitative Detection of Anti-Interferon-Gamma Antibody by Using a Nanometer Biolinker.
Topics: Animals; Antibodies; Biosensing Techniques; Dextrans; Gold; Humans; Immobilized Proteins; Interferon-gamma; Mice; Nanotechnology; Sensitivity and Specificity; Thiophenes | 2016 |
"Sign-on/off" sensing interface design and fabrication for propyl gallate recognition and sensitive detection.
Topics: Conductometry; Electrodes; Equipment Design; Equipment Failure Analysis; Food Additives; Food Analysis; Molecular Imprinting; Polymers; Propyl Gallate; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2016 |
Selective detection of dopamine with an all PEDOT:PSS Organic Electrochemical Transistor.
Topics: Amino Acids; Ascorbic Acid; Dopamine; Electrochemical Techniques; Oxidation-Reduction; Polystyrenes; Sensitivity and Specificity; Thiophenes; Transistors, Electronic; Uric Acid | 2016 |
Synthesis and antiproliferative activity of monocationic arylthiophene derivatives.
Topics: Antineoplastic Agents; Antioxidants; Benzamidines; Cell Death; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Protein-Tyrosine Kinases; Sensitivity and Specificity; Thiophenes | 2017 |
Lactate Detection in Tumor Cell Cultures Using Organic Transistor Circuits.
Topics: Animals; Biosensing Techniques; Calibration; Cattle; Cell Culture Techniques; Chitosan; Electric Impedance; Electrochemical Techniques; Equipment Design; Ferrous Compounds; Humans; Lactic Acid; Leukocytes, Mononuclear; Metallocenes; Mixed Function Oxygenases; Neoplasms; Polystyrenes; Sensitivity and Specificity; Serum Albumin, Bovine; Thiophenes; Transistors, Electronic | 2017 |
Non-canonical amino acids bearing thiophene and bithiophene: synthesis by an Ugi multicomponent reaction and studies on ion recognition ability.
Topics: Aldehydes; Amines; Amino Acids; Biomimetic Materials; Cations; Coordination Complexes; Copper; Cyanides; Fluorescent Dyes; Heterocyclic Compounds; Iron; Sensitivity and Specificity; Solutions; Spectrometry, Fluorescence; Thiophenes | 2017 |
Amino(oligo)thiophene-based environmentally sensitive biomembrane chromophores.
Topics: Aldehydes; Amines; Carbocyanines; Fluorescent Dyes; Membrane Potentials; Optics and Photonics; Photons; Pyridinium Compounds; Pyrroles; Sensitivity and Specificity; Solvents; Spectrometry, Fluorescence; Thiophenes; Viscosity | 2008 |
Fluorescence "turn-on" sensing of carboxylate anions with oligothiophene-based o-(carboxamido)trifluoroacetophenones.
Topics: Acetophenones; Amides; Anions; Carboxylic Acids; Fluorescence; Fluorescent Dyes; Hydrocarbons, Fluorinated; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Chemical; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes; Titrimetry | 2008 |
Determination of rivaroxaban--a novel, oral, direct Factor Xa inhibitor--in human plasma by high-performance liquid chromatography-tandem mass spectrometry.
Topics: Calibration; Chromatography, High Pressure Liquid; Factor Xa Inhibitors; Humans; Morpholines; Reproducibility of Results; Rivaroxaban; Sensitivity and Specificity; Serine Proteinase Inhibitors; Tandem Mass Spectrometry; Thiophenes | 2008 |
The effect of the oxidation state of a terthiophene-conducting polymer and of the presence of a redox probe on its gene-sensing properties.
Topics: Bacterial Proteins; Biosensing Techniques; DNA, Bacterial; Electric Conductivity; Electrochemistry; Equipment Design; Equipment Failure Analysis; Gene Expression Profiling; Oxidation-Reduction; Polymers; Reproducibility of Results; Salmonella; Sensitivity and Specificity; Thiophenes | 2008 |
Sensitive and selective detection of aspartic acid and glutamic acid based on polythiophene-gold nanoparticles composite.
Topics: Aspartic Acid; Glutamic Acid; Gold; Metal Nanoparticles; Microscopy, Electron, Transmission; Molecular Structure; Polymers; Reproducibility of Results; Sensitivity and Specificity; Solutions; Spectrophotometry; Thiophenes | 2008 |
Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Carbohydrate Metabolism; Catalytic Domain; Chlorocebus aethiops; COS Cells; Enzyme Activation; Glucose; Hepatocytes; Isoenzymes; Mice; Pyrones; Recombinant Proteins; Sensitivity and Specificity; Substrate Specificity; Thiophenes | 2008 |
Sensitive determination of dopamine and uric acid by the use of a glassy carbon electrode modified with poly(3-methylthiophene)/gold nanoparticle composites.
Topics: Ascorbic Acid; Carbon; Catalysis; Dopamine; Electric Impedance; Electrochemistry; Electrodes; Glass; Gold; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Microscopy, Electron, Scanning; Nanocomposites; Oxidation-Reduction; Polymers; Reproducibility of Results; Sensitivity and Specificity; Surface Properties; Thiophenes; Uric Acid | 2008 |
Selective histamine piezoelectric chemosensor using a recognition film of the molecularly imprinted polymer of bis(bithiophene) derivatives.
Topics: Buffers; Chemistry Techniques, Analytical; Electrochemistry; Flow Injection Analysis; Histamine; Hydrogen-Ion Concentration; Molecular Imprinting; Polymers; Quartz; Sensitivity and Specificity; Thiophenes; Transducers | 2009 |
[Differentiation of species within the Mycobacterium tuberculosis complex by molecular techniques].
Topics: Animals; Bacterial Proteins; Carboxylic Acids; Cattle; Chaperonin 60; DNA Gyrase; DNA, Bacterial; Humans; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Niacin; Nitrates; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrazinamide; Reference Standards; Sensitivity and Specificity; Species Specificity; Thiophenes; Tuberculosis; Tuberculosis, Bovine | 2009 |
Total residue analysis of swabs by ion mobility spectrometry.
Topics: Drug Industry; Duloxetine Hydrochloride; Excipients; Ions; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrum Analysis; Thiophenes | 2009 |
Electrochemical analysis of copper ion using a Gly-Gly-His tripeptide modified poly(3-thiopheneacetic acid) biosensor.
Topics: Biosensing Techniques; Copper; Electrochemistry; Electrodes; Oligopeptides; Polymers; Sensitivity and Specificity; Spectrometry, X-Ray Emission; Spectrophotometry, Infrared; Thiophenes | 2009 |
Ionic liquids as superior solvents for headspace gas chromatography of residual solvents with very low vapor pressure, relevant for pharmaceutical final dosage forms.
Topics: Cefpodoxime Proxetil; Ceftizoxime; Excipients; Gas Chromatography-Mass Spectrometry; Imidazoles; Ionic Liquids; Organophosphorus Compounds; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity; Solvents; Thiophenes; Vapor Pressure | 2009 |
Colorimetric and fluorometric detection of nucleic acids using cationic polythiophene derivatives.
Topics: Colorimetry; Nucleic Acids; Polymers; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes; Time Factors | 2002 |
Stress degradation studies on duloxetine hydrochloride and development of an RP-HPLC method for its determination in capsule formulation.
Topics: Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Duloxetine Hydrochloride; Hydrogen-Ion Concentration; Hydrolysis; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2009 |
J-compensated PGSE: an improved NMR diffusion experiment with fewer phase distortions.
Topics: Algorithms; Chloroform; Deuterium; Diffusion; Hydrocarbons, Brominated; Magnetic Resonance Spectroscopy; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spin Labels; Thiophenes | 2010 |
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.
Topics: Acetic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Amyloid; Amyloidosis; Female; Humans; Luminescent Agents; Male; Middle Aged; Molecular Structure; Polymers; Sensitivity and Specificity; Spectrometry, Fluorescence; Staining and Labeling; Thiophenes; Young Adult | 2010 |
Analytic model comparing the cost utility of TVT versus duloxetine in women with urinary stress incontinence.
Topics: Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Humans; Markov Chains; Models, Statistical; Quality-Adjusted Life Years; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Suburethral Slings; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2010 |
A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells.
Topics: Cell Line, Tumor; Cell Survival; Fluorescent Dyes; Humans; Mercury; Microscopy, Fluorescence; Rhodamines; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes | 2010 |
Rapid HPLC method for the simultaneous monitoring of duloxetine, venlaflaxine, fluoxetine and paroxetine in biofluids.
Topics: Chromatography, High Pressure Liquid; Cyclohexanols; Duloxetine Hydrochloride; Fluoxetine; Humans; Limit of Detection; Paroxetine; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Thiophenes; Venlafaxine Hydrochloride | 2009 |
Detection of liposome membrane viscosity perturbations with ratiometric molecular rotors.
Topics: 1-Propanol; Calibration; Coumarins; Fluorescent Dyes; Humans; Liposomes; Molecular Conformation; Phosphatidylcholines; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes; Viscosity | 2011 |
Stereoselective HPLC analysis of tertatolol in rat plasma using macrocyclic antibiotic chiral stationary phase.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Drug Monitoring; Male; Propanolamines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Thiophenes; Vancomycin | 2011 |
Electrospray ionization LC-MS/MS validated method for the determination of the active metabolite (R-138727) of prasugrel in human plasma and its application to a bioequivalence study.
Topics: Adolescent; Adult; Chromatography, Liquid; Humans; Linear Models; Male; Piperazines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thiophenes; Young Adult | 2012 |
Ag(I)-cysteamine complex based electrochemical stripping immunoassay: ultrasensitive human IgG detection.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Immobilized; Biosensing Techniques; Cysteamine; Electrochemical Techniques; Gold; Humans; Immunoassay; Immunoglobulin G; Limit of Detection; Metal Nanoparticles; Polymers; Sensitivity and Specificity; Silver; Thiophenes | 2011 |
Log-scale dose response of inhibitors on a chip.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Kinetics; Lab-On-A-Chip Devices; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Microchip Analytical Procedures; Neoplasms; Phenylalanine; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes | 2011 |
Electropolymerized self-assembled layer on gold nanoparticles: detection of inducible nitric oxide synthase in neuronal cell culture.
Topics: Antibodies, Immobilized; Benzoic Acid; Biosensing Techniques; Cell Culture Techniques; Dielectric Spectroscopy; Electrochemistry; Electrodes; Gold; Limit of Detection; Nanoparticles; Neurons; Nitric Oxide Synthase Type II; Polymerization; Potentiometry; Sensitivity and Specificity; Thiophenes | 2011 |
Quantification of oltipraz using liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study in rat plasma.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Pyrazines; Rats; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Thiones; Thiophenes | 2011 |
Rivaroxaban: Quantification by anti-FXa assay and influence on coagulation tests: a study in 9 Swiss laboratories.
Topics: Adult; Anticoagulants; Artifacts; Blood Coagulation Tests; Drug Monitoring; Factor Xa Inhibitors; Humans; Male; Morpholines; Reproducibility of Results; Rivaroxaban; Sensitivity and Specificity; Switzerland; Thiophenes | 2012 |
Amplification strategy using aggregates of ferrocene-containing cationic polythiophene for sensitive and specific electrochemical detection of DNA.
Topics: Biosensing Techniques; Cations; DNA; DNA Probes; Electrochemistry; Electrodes; Ferrous Compounds; Gold; Metallocenes; Nanostructures; Peptide Nucleic Acids; Polymers; Sensitivity and Specificity; Thiophenes | 2011 |
Determination of an international sensitivity index of thromboplastin reagents using a WHO thromboplastin as calibrator for plasma spiked with rivaroxaban.
Topics: Anticoagulants; Blood Coagulation; Calibration; Coagulants; Humans; Indicators and Reagents; International Normalized Ratio; Morpholines; Plasma; Prothrombin Time; Recombinant Proteins; Regression Analysis; Rivaroxaban; Sensitivity and Specificity; Thiophenes; Thromboplastin | 2011 |
Distinct effects of cevimeline and pilocarpine on salivary mechanisms, cardiovascular response and thirst sensation in rats.
Topics: Analysis of Variance; Animals; Cardiovascular System; Drinking; Muscarinic Agonists; Parotid Gland; Pilocarpine; Quinuclidines; Rats; Rats, Wistar; Salivation; Sensitivity and Specificity; Subfornical Organ; Thiophenes; Thirst | 2012 |
Cobalt(II) selective membrane electrode based on palladium(II) dichloro acetylthiophene fenchone azine.
Topics: Camphanes; Cobalt; Electrochemical Techniques; Electrodes; Hydrocarbons, Chlorinated; Ions; Membranes, Artificial; Norbornanes; Palladium; Sensitivity and Specificity; Thiophenes; Water; Water Pollutants, Chemical | 2011 |
Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls.
Topics: Anticoagulants; Blood Chemical Analysis; Calibration; Chromogenic Compounds; Europe; Factor Xa Inhibitors; Feasibility Studies; Humans; Morpholines; North America; Observer Variation; Reproducibility of Results; Rivaroxaban; Sensitivity and Specificity; Thiophenes | 2012 |
Darexaban has high sensitivity in the prothrombin time clotting test.
Topics: Azepines; Benzamides; Blood Coagulation; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Fibrinolytic Agents; Glucuronides; Humans; Morpholines; Predictive Value of Tests; Prothrombin Time; Pyrazoles; Pyridones; Rivaroxaban; Sensitivity and Specificity; Thiophenes | 2012 |
Development of novel molecularly imprinted solid-phase microextraction fibers and their application for the determination of antibiotic drugs in biological samples by SPME-LC/MS(n).
Topics: Acetamides; Amoxicillin; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Daptomycin; Humans; Linezolid; Mass Spectrometry; Molecular Imprinting; Oxazolidinones; Polymers; Pyrroles; Sensitivity and Specificity; Solid Phase Microextraction; Thiophenes | 2012 |
A novel and rapid validated stability-indicating UPLC method of related substances for dorzolamide hydrochloride and timolol maleate in ophthalmic dosage form.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Contamination; Drug Stability; Hydrogen-Ion Concentration; Linear Models; Models, Molecular; Ophthalmic Solutions; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Thiophenes; Timolol | 2012 |
Real-time determination of the activity of ATPase by use of a water-soluble polythiophene.
Topics: Adenosine Triphosphatases; Biological Assay; Enzyme Activation; Fluorescence; Humans; Male; Polymers; Sensitivity and Specificity; Solubility; Thiophenes; Water | 2012 |
Electrochemically synthesized molecularly imprinted polymer of thiophene derivatives for flow-injection analysis determination of adenosine-5'-triphosphate (ATP).
Topics: Adenosine Triphosphate; Biosensing Techniques; Conductometry; Electroplating; Equipment Design; Equipment Failure Analysis; Flow Injection Analysis; Micro-Electrical-Mechanical Systems; Microfluidic Analytical Techniques; Molecular Imprinting; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2013 |
Biodegradation of crude oil across a wide range of salinities by an extremely halotolerant bacterial consortium MPD-M, immobilized onto polypropylene fibers.
Topics: Avicennia; Bacteria; Biodegradation, Environmental; Biofilms; Cell Adhesion; Cells, Cultured; Cells, Immobilized; Diterpenes; Hydrocarbons; Naphthalenes; Petroleum; Plant Roots; Polypropylenes; Sensitivity and Specificity; Sodium Chloride; Terpenes; Thiophenes | 2002 |
Analysis of aromatic sulfur compounds in gas oils using GC with sulfur chemiluminescence detection and high-resolution MS.
Topics: Gas Chromatography-Mass Spectrometry; Luminescent Measurements; Petroleum; Polycyclic Aromatic Hydrocarbons; Sensitivity and Specificity; Sulfur Compounds; Thiophenes | 2002 |
Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Benzofurans; Butylamines; Corticosterone; Drug Administration Schedule; Drug Evaluation, Preclinical; Escape Reaction; Hypokinesia; Male; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Rats; Rats, Wistar; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Swimming; Thiophenes | 2003 |
Evaluation of vascular endothelial growth factor blockade and matrix metalloproteinase inhibition as a combination therapy for experimental human pancreatic cancer.
Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Chi-Square Distribution; Disease Models, Animal; Drug Therapy, Combination; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Pancreatic Neoplasms; Phenylalanine; Probability; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Selective cleavage of 10-methyl benzo[b]naphtho[2,1-d]thiophene by recombinant Mycobacterium sp. strain.
Topics: Biodegradation, Environmental; Mycobacterium; Naphthalenes; Recombination, Genetic; Sensitivity and Specificity; Species Specificity; Sulfur; Thiophenes | 2003 |
Poly-3-hexyl thiophene Langmuir-Blodgett films for application to glucose biosensor.
Topics: Biosensing Techniques; Coated Materials, Biocompatible; Electrochemistry; Enzymes, Immobilized; Equipment Failure Analysis; Glucose; Glucose Oxidase; Materials Testing; Membranes, Artificial; Polymers; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2004 |
In vitro antifungal activity of sertaconazole against 309 dermatophyte clinical isolates.
Topics: Antifungal Agents; Arthrodermataceae; Dermatomycoses; Drug Resistance, Fungal; Female; Fungi; Humans; Imidazoles; Male; Microbial Sensitivity Tests; Sensitivity and Specificity; Thiophenes | 2003 |
A performance comparison of choline biosensors: anodic or cathodic detections of H2O2 generated by enzyme immobilized on a conducting polymer.
Topics: Alcohol Oxidoreductases; Biosensing Techniques; Choline; Coenzymes; Electric Conductivity; Electrochemistry; Electrodes; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Horseradish Peroxidase; Hydrogen Peroxide; Membranes, Artificial; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2004 |
Electrochemical dimerization of 2-(2'-thienyl)pyridine adsorbed on Au(111) observed by in situ fluorescence.
Topics: Adsorption; Electrochemistry; Electrodes; Gold; Microscopy, Fluorescence; Molecular Structure; Pyridines; Sensitivity and Specificity; Surface Properties; Thienopyridines; Thiophenes | 2004 |
Preparation of bis(diazo) compounds incorporated into butadiyne and thiophene units and generation and characterization of their photoproducts.
Topics: Alkynes; Diazonium Compounds; Electron Spin Resonance Spectroscopy; Molecular Structure; Photochemistry; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Temperature; Thiophenes | 2005 |
Verification of statistical-overlap theory in micellar electrokinetic chromatography.
Topics: Chromatography, Micellar Electrokinetic Capillary; Esters; Hydrocarbons, Aromatic; Ketones; Models, Theoretical; Monte Carlo Method; Nucleosides; Purines; Pyrimidines; Sensitivity and Specificity; Thiophenes | 2005 |
A sensitive colorimetric and fluorescent probe based on a polythiophene derivative for the detection of ATP.
Topics: Adenosine Triphosphate; Anions; Colorimetry; Fluorescent Dyes; Molecular Structure; Sensitivity and Specificity; Thiophenes | 2005 |
Sample size and statistical power assessing the effect of interventions in the context of mixture distributions with detection limits.
Topics: Aflatoxin M1; Cohort Studies; Computer Simulation; Drug Evaluation; Food Contamination; Humans; Models, Statistical; Monte Carlo Method; Pyrazines; Randomized Controlled Trials as Topic; Sample Size; Sensitivity and Specificity; Thiones; Thiophenes | 2006 |
Infrared imaging of the nanometer-thick accumulation layer in organic field-effect transistors.
Topics: Chemical Phenomena; Chemistry, Physical; Equipment Design; Membranes, Artificial; Nanotechnology; Particle Size; Sensitivity and Specificity; Spectrophotometry, Infrared; Surface Properties; Thiophenes; Titanium; Transistors, Electronic | 2006 |
Visible photooxidation of dibenzothiophenes sensitized by 2-(4-methoxyphenyl)-4, 6-diphenylpyrylium: an electron transfer mechanism without involvement of superoxide.
Topics: Electron Spin Resonance Spectroscopy; Electrons; Free Radicals; Light; Molecular Structure; Oxidation-Reduction; Oxygen; Photochemistry; Pyrans; Sensitivity and Specificity; Superoxides; Thiophenes; Time Factors | 2006 |
Thiophene-thiophene versus phenyl-phenyl coupling in 2-(Diphenylamino)-Thiophenes: an ESR-UV/Vis/NIR spectroelectrochemical study.
Topics: Diphenylamine; Electrochemistry; Electron Spin Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Spectroscopy, Near-Infrared; Stereoisomerism; Thiophenes | 2006 |
Validation of a solid phase extraction-high performance liquid chromatographic method for the determination of eprosartan in human plasma.
Topics: Acrylates; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Stability; Humans; Imidazoles; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2006 |
Determination of the enantiomeric composition of a new insulin sensitizer in plasma samples from non-clinical and clinical investigations using chiral HPLC with electrospray tandem mass spectrometric detection.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Hypoglycemic Agents; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Thiazoles; Thiazolidinediones; Thiophenes | 2006 |
Highly selective and sensitive determination of dopamine using a Nafion/carbon nanotubes coated poly(3-methylthiophene) modified electrode.
Topics: Biosensing Techniques; Coated Materials, Biocompatible; Dopamine; Electrochemistry; Equipment Design; Equipment Failure Analysis; Fluorocarbon Polymers; Microelectrodes; Nanotubes, Carbon; Particle Size; Polymers; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2006 |
Determination of thiencynonate by liquid chromatographic-mass spectrometry and its application to pharmacokinetics in rats.
Topics: Administration, Oral; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calibration; Cholinergic Antagonists; Chromatography, High Pressure Liquid; Male; Molecular Structure; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Thiophenes | 2006 |
Conformational analysis of 2,2'-bithiophene: a (1)H liquid crystal NMR study using the (13)C satellite spectra.
Topics: Carbon Isotopes; Crystallization; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Protons; Quantum Theory; Reference Standards; Sensitivity and Specificity; Thiophenes; Vibration | 2005 |
Synthesis and characterization of a novel terthiophene-based quinodimethane bearing a 3,4-ethylenedioxythiophene central unit.
Topics: Electrochemistry; Methane; Models, Chemical; Molecular Structure; Nitriles; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thiophenes | 2005 |
Spectral and photophysical studies on cruciform oligothiophenes in solution and the solid state.
Topics: Combinatorial Chemistry Techniques; Molecular Structure; Oxygen; Photochemistry; Sensitivity and Specificity; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiophenes | 2006 |
BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway.
Topics: B-Cell Activating Factor; B-Cell Maturation Antigen; Carboxylic Acids; Cell Fractionation; Cell Survival; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; NF-kappa B; Protein Kinase Inhibitors; Sensitivity and Specificity; Signal Transduction; Thiophenes; Transmembrane Activator and CAML Interactor Protein; Tumor Necrosis Factor Ligand Superfamily Member 13 | 2007 |
Monolayer to multilayer nanostructural growth transition in N-type oligothiophenes on Au(111) and implications for organic field-effect transistor performance.
Topics: Electric Conductivity; Electrochemistry; Fluorocarbons; Gold; Materials Testing; Membranes, Artificial; Microscopy, Scanning Tunneling; Nanostructures; Particle Size; Semiconductors; Sensitivity and Specificity; Silicon Dioxide; Surface Properties; Thiophenes | 2006 |
Poly-(3-hexylthiophene) self-assembled monolayer based cholesterol biosensor using surface plasmon resonance technique.
Topics: Adsorption; Biosensing Techniques; Cholesterol; Coated Materials, Biocompatible; Crystallization; Equipment Design; Equipment Failure Analysis; Membranes, Artificial; Reproducibility of Results; Sensitivity and Specificity; Surface Plasmon Resonance; Surface Properties; Thiophenes | 2007 |
Electronic communication and negative binding cooperativity in diborylated bithiophenes.
Topics: Binding Sites; Boron Compounds; Electrochemistry; Electrons; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Photochemistry; Pyridines; Quantum Theory; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiophenes | 2006 |
Thickness dependence of microstructure in semiconducting films of an oligofluorene derivative.
Topics: Crystallography, X-Ray; Fluorenes; Membranes, Artificial; Microscopy, Atomic Force; Models, Molecular; Molecular Structure; Particle Size; Semiconductors; Sensitivity and Specificity; Thiophenes | 2006 |
Giant macrocycles composed of thiophene, acetylene, and ethylene building blocks.
Topics: Acetylene; Crystallography, X-Ray; Electrochemistry; Electrons; Ethylenes; Macrocyclic Compounds; Models, Molecular; Molecular Structure; Oxidation-Reduction; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes | 2006 |
Integrated thin-film polymer/fullerene photodetectors for on-chip microfluidic chemiluminescence detection.
Topics: Dimethylpolysiloxanes; Equipment Design; Fullerenes; Luminescent Measurements; Microfluidic Analytical Techniques; Photochemistry; Sensitivity and Specificity; Silicones; Thiophenes | 2007 |
Push-pull bithienyl chromophore with an unusual transverse path of conjugation.
Topics: Crystallography, X-Ray; Models, Chemical; Models, Molecular; Molecular Structure; Quantum Theory; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Sulfur Compounds; Thiepins; Thiophenes | 2007 |
Redistribution of emitting state population in conjugated polymers probed by single-molecule fluorescence polarization spectroscopy.
Topics: Fluorescence Polarization; Molecular Structure; Polymers; Sensitivity and Specificity; Spectrometry, Fluorescence; Temperature; Thiophenes; Time Factors | 2007 |
A multiresidue method for the analysis of pesticide residues in polished rice (Oryza sativa L.) using accelerated solvent extraction and gas chromatography and confirmation by mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Diazinon; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Molecular Structure; Oryza; Pesticide Residues; Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester; Plant Extracts; Pressure; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solvents; Temperature; Thiophenes | 2007 |
Molecular engineering in symmetric end-substituted oligothiophene derivatives: analysis of condensed-phase photoemission spectra using semiempirical Hartree-Fock calculations.
Topics: Computer Simulation; Models, Chemical; Quantum Theory; Sensitivity and Specificity; Spectrophotometry; Thiophenes | 2007 |
HPLC analysis of the novel antidepressant duloxetine in human plasma after an original solid-phase extraction procedure.
Topics: Antidepressive Agents; Calibration; Chromatography, High Pressure Liquid; Depression; Duloxetine Hydrochloride; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Thiophenes | 2007 |
Poly(3,4-ethylenedioxythiophene-co-(5-amino-2-naphthalenesulfonic acid)) (PEDOT-PANS) film modified glassy carbon electrode for selective detection of dopamine in the presence of ascorbic acid and uric acid.
Topics: Ascorbic Acid; Carbon; Catalysis; Dopamine; Electrodes; Glass; Naphthalenesulfonates; Oxidation-Reduction; Potentiometry; Sensitivity and Specificity; Thiophenes; Uric Acid | 2007 |
A water-soluble polythiophene-Au nanoparticle composite for pH sensing.
Topics: Electrodes; Gold; Hydrogen-Ion Concentration; Molecular Structure; Nanoparticles; Particle Size; Polymers; Sensitivity and Specificity; Solubility; Surface Properties; Thiophenes; Water | 2007 |
Label-free electrochemical detection of DNA using ferrocene-containing cationic polythiophene and PNA probes on nanogold modified electrodes.
Topics: Biosensing Techniques; Cations; DNA; DNA Probes; Electrochemistry; Equipment Design; Equipment Failure Analysis; Gold; Microelectrodes; Nanostructures; Oligonucleotide Array Sequence Analysis; Peptide Nucleic Acids; Polymers; Reproducibility of Results; Sensitivity and Specificity; Sequence Analysis, DNA; Staining and Labeling; Thiophenes | 2008 |
Pulmonary hypertension: basic concepts and practical management.
Topics: Bosentan; Endothelin Receptor Antagonists; Female; Humans; Hypertension, Pulmonary; Isoxazoles; Male; Receptors, Endothelin; Sensitivity and Specificity; Sulfonamides; Survival Analysis; Thiophenes; Treatment Outcome | 2008 |
UV-Vis-NIR spectroelectrochemical and in situ conductance studies of unusual stability of n- and p-doped poly(dimethyldioctylquaterthiophene-alt-oxadiazole) under high cathodic and anodic polarizations.
Topics: Electric Conductivity; Electrochemistry; Electrodes; Molecular Structure; Oxadiazoles; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Spectroscopy, Near-Infrared; Surface Properties; Thiophenes | 2008 |
Carbon nanotube/polythiophene chemiresistive sensors for chemical warfare agents.
Topics: Biosensing Techniques; Chemical Warfare Agents; Hydrogen Bonding; Nanotubes, Carbon; Organophosphorus Compounds; Polymers; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2008 |
Evaluation of an immunodot test to manage white spot syndrome virus (WSSV) during cultivation of the giant tiger shrimp Penaeus monodon.
Topics: Animals; Aquaculture; Furans; Gills; Immunoblotting; India; Penaeidae; Reproducibility of Results; Sensitivity and Specificity; Thiophenes; White spot syndrome virus 1 | 2008 |
Simultaneous determination of L-693,612, a topical carbonic anhydrase inhibitor, and two potential metabolites in human whole blood by ion-pair high-performance liquid chromatography.
Topics: Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Humans; Ions; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes | 1994 |
Electrogenic and electroneutral HCO3-secretion by guinea pig gallbladder epithelium: discriminatory abilities of Cl- channel blockers.
Topics: Alprostadil; Animals; Bicarbonates; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carrier Proteins; Chloride Channels; Chloride-Bicarbonate Antiporters; Chlorides; Electrophysiology; Epithelium; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Membrane Proteins; Mitochondria; Neural Conduction; Nitrobenzoates; ortho-Aminobenzoates; Sensitivity and Specificity; Thiophenes | 1993 |
Low level determination of dorzolamide and its de-ethylated metabolite in human plasma by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes | 1997 |
Analysis of prostaglandin G/H synthase-2 inhibition using peroxidase-induced luminol luminescence.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Binding, Competitive; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indicators and Reagents; Inhibitory Concentration 50; Isoenzymes; Kinetics; Luminol; Membrane Proteins; Peroxidases; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Sensitivity and Specificity; Thiophenes; Time Factors | 1998 |
Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method.
Topics: Antineoplastic Agents, Alkylating; Biomarkers; Busulfan; Calibration; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Kinetics; Liver; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 1999 |
The plasma pharmacokinetics and cerebrospinal fluid penetration of the thymidylate synthase inhibitor raltitrexed (Tomudex) in a nonhuman primate model.
Topics: Animals; Antimetabolites, Antineoplastic; Half-Life; Infusions, Intravenous; Macaca mulatta; Male; Metabolic Clearance Rate; Models, Biological; Quinazolines; Sensitivity and Specificity; Thiophenes; Thymidylate Synthase | 1999 |
Ultratrace analysis of drugs in biological fluids using affinity probe capillary electrophoresis: analysis of dorzolamide with fluorescently labeled carbonic anhydrase.
Topics: Animals; Body Fluids; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Electrophoresis, Capillary; Humans; Sensitivity and Specificity; Sulfonamides; Thiophenes | 2000 |
Analysis of the dynamics of fungal communities in soil via fungal-specific PCR of soil DNA followed by denaturing gradient gel electrophoresis.
Topics: Base Composition; DNA, Fungal; DNA, Ribosomal; Ecology; Electrophoresis, Polyacrylamide Gel; Fungi; Gasoline; Mitosporic Fungi; Nucleic Acid Denaturation; Polymerase Chain Reaction; RNA, Ribosomal, 18S; Sensitivity and Specificity; Soil Microbiology; Soil Pollutants; Thiophenes | 2000 |
The impact of p53 status on cellular sensitivity to antifolate drugs.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Mutational Analysis; DNA, Neoplasm; Dose-Response Relationship, Drug; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Genotype; Glutamates; Guanine; Humans; Methotrexate; Mutation; Pemetrexed; Quinazolines; Sensitivity and Specificity; Tetrahydrofolates; Thiophenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
alpha(v)beta(3) Antagonists based on a central thiophene scaffold.
Topics: Animals; Binding Sites; Carbamates; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Guanidine; Osteoporosis; Parathyroidectomy; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Receptors, Vitronectin; Sensitivity and Specificity; Sulfonamides; Thiophenes; Thyroidectomy | 2001 |
Design and synthesis of a highly selective EP4-receptor agonist. Part 2: 5-thia and 9beta-haloPG derivatives with improved stability.
Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Cyclic AMP; Cyclopentanes; Drug Design; Halogens; Humans; Ligands; Mice; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Sensitivity and Specificity; Sulfur; Sulfur Compounds; Thiophenes | 2001 |