n,n'-diallyltartardiamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

N,N'-diallyltartardiamide: cross linking reagent; RN given refers to (R-(R*,R*))-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	98486
CHEBI ID	184080
SCHEMBL ID	107767
MeSH ID	M0054445

Synonyms (38)

Synonym
butanediamide, 2,3-dihydroxy-n,n'-di-2-propenyl-
CBDIVE_003321
n,n'-diallyl-2,3-dihydroxy-butanediamide
n~1~,n~4~-diallyl-2,3-dihydroxysuccinamide
nsc145415
nsc-145415
28843-34-7
n,n'-diallyltartardiamide
D-0950
datd
n,n'-diallyltartramide
inchi=1/c10h16n2o4/c1-3-5-11-9(15)7(13)8(14)10(16)12-6-4-2/h3-4,7-8,13-14h,1-2,5-6h2,(h,11,15)(h,12,16)
2,3-dihydroxy-n,n'-di(prop-2-enyl)butanediamide
zrkleahgbndkhm-uhfffaoysa-
D1539
(+)-n,n'-diallyl-l-tartramide
(+)-n,n'-diallyl-l-tartardiamide
2,3-dihydroxy-n,n'-bis(prop-2-enyl)butanediamide
CHEBI:184080
n,n'-diallyl-2,3-dihydroxysuccinamide
(2r,3r)-2,3-dihydroxy-n,n'-bis(prop-2-enyl)butanediamide
AKOS004903293
ai3-62352
nsc 145415
einecs 249-267-7
FT-0629377
FT-0629378
FT-0629435
SCHEMBL107767
n,n'-diallyl-l-(+)-tartardiamide
butanediamide, 2,3-dihydroxy-n,n'-di-2-propenyl-, [r-(r,r)]-
(+)-n,n'-diallyltartardiamide
ZRKLEAHGBNDKHM-UHFFFAOYSA-N
n,n'-diallyl tartardiamide
butanediamide,2,3-dihydroxy-n1,n4-di-2-propen-1-yl-
n1,n4-diallyl-2,3-dihydroxysuccinamide
2,3-dihydroxy-n~1~,n~4~-di(prop-2-en-1-yl)butanediamide
DTXSID50866693

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
fatty amide	A monocarboxylic acid amide derived from a fatty acid.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (11)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (54.55)	18.7374
1990's	3 (27.27)	18.2507
2000's	2 (18.18)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (9.09%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (90.91%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
bupivacaine Bupivacaine: A widely used local anesthetic agent.. 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.. bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.	2.02	1	aromatic amide; piperidinecarboxamide; tertiary amino compound
cystamine [no description available]	2	1	organic disulfide; primary amino compound	EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor
ethidium Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.. ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.	1.97	1	phenanthridines	fluorochrome; intercalator
thalidomide Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.. thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.. 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.	2.02	1	phthalimides; piperidones
floxuridine Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.. floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.	1.95	1	nucleoside analogue; organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; radiosensitizing agent
acrylamide [no description available]	2	1	acrylamides; N-acylammonia; primary carboxamide	alkylating agent; carcinogenic agent; Maillard reaction product; mutagen; neurotoxin
n,n'-methylenebisacrylamide [no description available]	8.97	4
vancomycin Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.	2.02	1	glycopeptide	antibacterial drug; antimicrobial agent; bacterial metabolite
silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.	1.97	1	copper group element atom; elemental silver	Escherichia coli metabolite
n,n'-(1,2-dihydroxyethylene)bisacrylamide [no description available]	2	1
warfarin Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.	2.02	1	benzenes; hydroxycoumarin; methyl ketone

Condition	Indicated	Relationship Strength	Studies	Trials
Spherocytosis, Hereditary A group of familial congenital hemolytic anemias characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. The erythrocytes have increased osmotic fragility and are abnormally permeable to sodium ions.	0	2	1	0
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	0	1.97	1	0

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