| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Congenital Zika Syndrome
[description not available] | 0 | 2.25 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 3.59 | 7 | 0 |
Zika Virus Infection
A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME. | 0 | 2.25 | 1 | 0 |
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 2.93 | 3 | 0 |
Leiomyosarcoma, Epithelioid
[description not available] | 0 | 2.41 | 1 | 0 |
Cancer of the Uterus
[description not available] | 0 | 2.41 | 1 | 0 |
Leiomyosarcoma
A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865) | 0 | 2.41 | 1 | 0 |
Uterine Neoplasms
Tumors or cancer of the UTERUS. | 0 | 2.41 | 1 | 0 |
Acute Myelogenous Leukemia
[description not available] | 0 | 2.9 | 3 | 0 |
Leukemia, Myeloid, Acute
Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. | 0 | 2.9 | 3 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 2.6 | 1 | 0 |
Palmoplantaris Pustulosis
[description not available] | 0 | 2.6 | 1 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 2.6 | 1 | 0 |
Psoriasis
A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. | 0 | 2.6 | 1 | 0 |
Colorectal Cancer
[description not available] | 0 | 3.52 | 4 | 0 |
Colorectal Neoplasms
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 3.52 | 4 | 0 |
Benign Neoplasms
[description not available] | 0 | 7.56 | 15 | 0 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 1 | 9.56 | 15 | 0 |
Adenocarcinoma, Basal Cell
[description not available] | 0 | 2.21 | 1 | 0 |
Cancer of Pancreas
[description not available] | 0 | 2.21 | 1 | 0 |
Carcinoma, Ductal, Pancreatic
[description not available] | 0 | 2.21 | 1 | 0 |
Adenocarcinoma
A malignant epithelial tumor with a glandular organization. | 0 | 2.21 | 1 | 0 |
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 2.21 | 1 | 0 |
Carcinoma, Pancreatic Ductal
Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS. | 0 | 2.21 | 1 | 0 |
Germinoblastoma
[description not available] | 0 | 2.25 | 1 | 0 |
Lymphoma
A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 2.25 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 2.25 | 1 | 0 |
Cancer of Ovary
[description not available] | 0 | 3.83 | 3 | 0 |
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 3.83 | 3 | 0 |
Cystadenocarcinoma, Serous
A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly epithelial overgrowths with differentiated and undifferentiated papillary serous cystadenocarcinoma cells. Psammoma bodies may be present. The tumor generally adheres to surrounding structures and produces ascites. (From Hughes, Obstetric-Gynecologic Terminology, 1972, p185) | 0 | 3.83 | 3 | 0 |
Leucocythaemia
[description not available] | 0 | 2.25 | 1 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.25 | 1 | 0 |
Carcinogenesis
The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. | 0 | 3.23 | 1 | 0 |
Carcinoma, Squamous Cell of Head and Neck
[description not available] | 0 | 2.31 | 1 | 0 |
Cancer of Mouth
[description not available] | 0 | 2.31 | 1 | 0 |
Squamous Cell Carcinoma of Head and Neck
The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer. | 0 | 2.31 | 1 | 0 |
Mouth Neoplasms
Tumors or cancer of the MOUTH. | 0 | 2.31 | 1 | 0 |
Pulmonary Arterial Remodeling
[description not available] | 0 | 2.63 | 2 | 0 |
Pulmonary Arterial Hypertension
A progressive rare pulmonary disease characterized by high blood pressure in the PULMONARY ARTERY. | 0 | 2.31 | 1 | 0 |
ER-Negative PR-Negative HER2-Negative Breast Cancer
[description not available] | 0 | 2.31 | 1 | 0 |
Triple Negative Breast Neoplasms
Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN. | 0 | 2.31 | 1 | 0 |
Cancer of Prostate
[description not available] | 0 | 2.59 | 2 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.59 | 2 | 0 |
Kahler Disease
[description not available] | 0 | 2.15 | 1 | 0 |
Multiple Myeloma
A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. | 0 | 2.15 | 1 | 0 |
Franceschetti-Zwahlen-Klein Syndrome
[description not available] | 0 | 2.17 | 1 | 0 |
Cytomegalovirus
A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS. | 0 | 2.17 | 1 | 0 |
Glial Cell Tumors
[description not available] | 0 | 2.17 | 1 | 0 |
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 2.17 | 1 | 0 |
Genome Instability
[description not available] | 0 | 2.17 | 1 | 0 |
Androgen-Independent Prostatic Cancer
[description not available] | 0 | 2.17 | 1 | 0 |
Prostatic Neoplasms, Castration-Resistant
Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE. | 1 | 4.17 | 1 | 0 |
Facies
The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed) | 0 | 2.17 | 1 | 0 |
Nanism
[description not available] | 0 | 2.17 | 1 | 0 |
Microcephaly
A congenital abnormality in which the CEREBRUM is underdeveloped, the fontanels close prematurely, and, as a result, the head is small. (Desk Reference for Neuroscience, 2nd ed.) | 0 | 2.17 | 1 | 0 |
Dwarfism
A genetic or pathological condition that is characterized by short stature and undersize. Abnormal skeletal growth usually results in an adult who is significantly below the average height. | 0 | 2.17 | 1 | 0 |
Neointima
The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement. | 0 | 2.57 | 2 | 0 |
Aortic Diseases
Pathological processes involving any part of the AORTA. | 0 | 2.17 | 1 | 0 |
Arteriosclerosis
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. | 0 | 2.17 | 1 | 0 |
Hematologic Malignancies
[description not available] | 0 | 4.21 | 3 | 1 |
Hematologic Neoplasms
Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. | 0 | 4.21 | 3 | 1 |
Aortic Dissection
[description not available] | 0 | 2.21 | 1 | 0 |
Allergic Encephalomyelitis
[description not available] | 0 | 2.52 | 2 | 0 |
Cell Transformation, Neoplastic
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. | 0 | 3.01 | 1 | 0 |
Cancer of Colon
[description not available] | 0 | 2.1 | 1 | 0 |
Colonic Neoplasms
Tumors or cancer of the COLON. | 0 | 2.1 | 1 | 0 |
Acute Lymphoid Leukemia
[description not available] | 0 | 2.52 | 2 | 0 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias. | 0 | 2.52 | 2 | 0 |
B-Cell Lymphoma
[description not available] | 0 | 2.13 | 1 | 0 |
Lymphoma, B-Cell
A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. | 0 | 2.13 | 1 | 0 |
Breast Cancer
[description not available] | 0 | 2.81 | 3 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 2.81 | 3 | 0 |
Hypertrophy
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA). | 0 | 2.13 | 1 | 0 |
Carcinoma, Small Cell Lung
[description not available] | 0 | 2.13 | 1 | 0 |
Cancer of Lung
[description not available] | 0 | 2.13 | 1 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 2.13 | 1 | 0 |
Small Cell Lung Carcinoma
A form of highly malignant lung cancer that is composed of small ovoid cells (SMALL CELL CARCINOMA). | 0 | 2.13 | 1 | 0 |
Invasiveness, Neoplasm
[description not available] | 0 | 2.13 | 1 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 2.13 | 1 | 0 |
Astrocytoma, Grade IV
[description not available] | 0 | 2.13 | 1 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2.13 | 1 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.13 | 1 | 0 |
MS (Multiple Sclerosis)
[description not available] | 0 | 2.15 | 1 | 0 |
Multiple Sclerosis
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) | 0 | 2.15 | 1 | 0 |
Carotid Arteriopathies, Traumatic
[description not available] | 0 | 2.15 | 1 | 0 |
Hyperplasia
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. | 0 | 2.15 | 1 | 0 |
Chromosomal Instability
An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional. | 0 | 3.06 | 1 | 0 |