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2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

A 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P62617]

Synonyms

MECDP-synthase;
MECPP-synthase;
MECPS;
EC 4.6.1.12

Research

Bioassay Publications (2)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Compounds (5)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
cytidine diphosphateEscherichia coli K-12IC50768.000011

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
5-fluorocytidineEscherichia coli K-12Kd2,020.000011
cyclic cmpEscherichia coli K-12Kd900.000011
cidofovir anhydrousEscherichia coli K-12Kd40,000.000011
1-beta-d-arabinofuranosylcytosine 5'-monophosphateEscherichia coli K-12Kd18,910.000011