Page last updated: 2024-08-07 12:58:15
Cytochrome P450 2D1
A protein that is a translation product of the Cyp2d1 gene in rat. [PRO:DNx, UniProtKB:P10633]
Synonyms
EC 1.14.14.1;
CYPIID1;
Cytochrome P450-CMF1A;
Cytochrome P450-DB1;
Cytochrome P450-UT-7;
Debrisoquine 4-hydroxylase
Research
Bioassay Publications (1)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (7)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| debrisoquin | Rattus norvegicus (Norway rat) | IC50 | 529.0000 | 1 | 1 |
| nortriptyline | Rattus norvegicus (Norway rat) | IC50 | 204.0000 | 1 | 1 |
| dexpropranolol | Rattus norvegicus (Norway rat) | IC50 | 182.0000 | 1 | 1 |
| quinidine | Rattus norvegicus (Norway rat) | IC50 | 19.9000 | 1 | 1 |
| quinine | Rattus norvegicus (Norway rat) | IC50 | 46.5000 | 1 | 1 |
| codeine | Rattus norvegicus (Norway rat) | IC50 | 1,320.0000 | 1 | 1 |
| dextromethorphan | Rattus norvegicus (Norway rat) | IC50 | 264.0000 | 1 | 1 |