Compounds > n-methyl-bis(trifluoroacetamide)
Page last updated: 2024-11-06

n-methyl-bis(trifluoroacetamide)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID69635
SCHEMBL ID9004789
MeSH IDM0063377

Synonyms (28)

Synonym
mbtfa
n-methyl-bis(trifluoroacetamide)
n-methyl-bis(trifluoroacetamide), for gc derivatization, >=97.0% (gc)
685-27-8
2,2,2-trifluoro-n-methyl-n-(2,2,2-trifluoroacetyl)acetamide
2,2,2-trifluoro-n-methyl-n-(trifluoroacetyl)acetamide
M0671
n,n-bis(trifluoroacetyl)methylamine
n-methylbis(trifluoroacetamide)
A9122
2,2,2-trifluoro-n-methyl-n-(trifluoroacetyl)acetamide; mbtfa
AKOS005206965
einecs 211-680-5
acetamide, 2,2,2-trifluoro-n-methyl-n-(trifluoroacetyl)-
FT-0632799
DTXSID00218623
SCHEMBL9004789
2,2,2-trifluoro-n-methyl-n-(trifluoroacetyl)acetamide #
mfcd00000412
n-methyl-bis(trifluoroacetamide), for gc derivatization, >=99.0% (gc)
n-methyl-bis(trifluoroacetamide), derivatization grade, 97%
n-methyl-bis(trifluoroacetamide), ~95% (capillary gc)
fmoc-(s)-3-amino-4-(4-trifluoromethylphenyl)butanoicacid
CS-0204515
2,2,2-trifluoro-n-methyl-n-(2,2,2-trifluoro-acetyl)-acetamide
n-methyl-bis-trifluoroacetamide
FS-5092
D91371
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.02

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.02 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.02)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
pipecolic acid
pipecolic acid: RN given refers to cpd without isomeric designation. pipecolic acid : A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.. pipecolate : A piperidinecarboxylate that is the conjugate base of pipecolic acid.		2.0510piperidinemonocarboxylic acid
amphetamine
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.. 1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.. amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.		2.3920primary amine
trifluoroacetic acid
Trifluoroacetic Acid: A very strong halogenated derivative of acetic acid. It is used in acid catalyzed reactions, especially those where an ester is cleaved in peptide synthesis.. trifluoroacetic acid : A monocarboxylic acid that is the trifluoro derivative of acetic acid.		2.9740fluoroalkanoic acidhuman xenobiotic metabolite;
NMR chemical shift reference compound;
reagent
methamphetamine
Methamphetamine: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.. methamphetamine : A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.		1.9710amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
1-(trimethylsilyl)-1h-imidazole
N-trimethylsilylimidazole : A member of the class of imidazoles in which the hydrogen at position 1 is replaced by a trimethylsilyl group. N-trimethylsilylimidazole is a derivatisation agent used in gas chromatography/mass spectrometry applications.		1.9710imidazoles;
N-silyl compound		chromatographic reagent
n-methyl-n-(trimethylsilyl)trifluoroacetamide
N-methyl-N-(trimethylsilyl)trifluoroacetamide : An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivatisation agent used in gas chromatography/mass spectrometry applications.		2.0510monocarboxylic acid amide;
N-silyl compound;
trifluoroacetamide		chromatographic reagent
n,n-bis(trimethylsilyl)-2,2,2-trifluoroacetamide
[no description available]		2.0610
benzyloxyamine
benzyloxyamine: RN given refers to parent cpd		1.9710
n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide
N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide : An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a tert-butyldimethylsilyl group.		2.0610monocarboxylic acid amide;
N-silyl compound;
trifluoroacetamide		chromatographic reagent
ConditionIndicatedRelationship StrengthStudiesTrials
Adrenoleukodystrophy, Autosomal Neonatal Form
[description not available]		02.0510
Peroxisomal Disorders
A heterogeneous group of inherited metabolic disorders marked by absent or dysfunctional PEROXISOMES. Peroxisomal enzymatic abnormalities may be single or multiple. Biosynthetic peroxisomal pathways are compromised, including the ability to synthesize ether lipids and to oxidize long-chain fatty acid precursors. Diseases in this category include ZELLWEGER SYNDROME; INFANTILE REFSUM DISEASE; rhizomelic chondrodysplasia (CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC); hyperpipecolic acidemia; neonatal adrenoleukodystrophy; and ADRENOLEUKODYSTROPHY (X-linked). Neurologic dysfunction is a prominent feature of most peroxisomal disorders.		02.0510
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.0610