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pantoprazole and Sensitivity and Specificity

pantoprazole has been researched along with Sensitivity and Specificity in 19 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"To determine the sensitivity and specificity of intensive empirical treatment with pantoprazole in diagnosing laryngopharyngeal reflux in adults."7.77Empirical treatment with pantoprazole as a diagnostic tool for symptomatic adult laryngopharyngeal reflux. ( Marina, MB; Masaany, M; Sani, A; Sharifa Ezat, WP, 2011)
"Pantoprazole 40 mg was at least as effective as esomeprazole 40 mg for relieving GERD symptoms."6.73Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse. ( Abdel-Qader, M; Gatz, G; Glatzel, D; Pfaffenberger, B, 2007)
"To determine the sensitivity and specificity of intensive empirical treatment with pantoprazole in diagnosing laryngopharyngeal reflux in adults."3.77Empirical treatment with pantoprazole as a diagnostic tool for symptomatic adult laryngopharyngeal reflux. ( Marina, MB; Masaany, M; Sani, A; Sharifa Ezat, WP, 2011)
"Pantoprazole 40 mg was at least as effective as esomeprazole 40 mg for relieving GERD symptoms."2.73Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse. ( Abdel-Qader, M; Gatz, G; Glatzel, D; Pfaffenberger, B, 2007)
" Both drugs induced similar false-negative UBTs on day 14 of dosing (P = 0."2.71Impact of long-term ranitidine and pantoprazole on accuracy of [13C]urea breath test. ( Biagini, R; Bilardi, C; Dulbecco, P; Gambaro, C; Iiritano, E; Mansi, C; Mele, MR; Savarino, V; Tessieri, L; Usai, P; Vigneri, S; Zentilin, P, 2003)
" The method was demonstrated with acceptable accuracy, precision, selectivity, and stability and the method was applied to support a pharmacokinetic study of a phase I clinical trial of racemic pantoprazole in healthy Chinese subjects."1.43High-Throughput Chiral LC-MS/MS Method Using Overlapping Injection Mode for the Determination of Pantoprazole Enantiomers in Human Plasma with Application to Pharmacokinetic Study. ( Hong, Z; Jiang, H; Li, S; Liang, W; Liu, Y; Shen, X; Wang, Y, 2016)
" The developed assay method was applied to a pharmacokinetic study in human volunteers."1.35Simultaneous estimation of four proton pump inhibitors--lansoprazole, omeprazole, pantoprazole and rabeprazole: development of a novel generic HPLC-UV method and its application to clinical pharmacokinetic study. ( Bharathi, DV; Chatki, PK; Hotha, KK; Jagadeesh, B; Mullangi, R; Naidu, A; Thriveni, K, 2009)
"Pantoprazole is an important drug in the treatment of acid-related disorders."1.33Preparation, characterization, and in vivo anti-ulcer evaluation of pantoprazole-loaded microparticles. ( Colomé, LM; Guterres, SS; Pohlmann, AR; Raffin, RP, 2006)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (63.16)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yehia, AM1
Li, S1
Jiang, H1
Wang, Y1
Liu, Y1
Shen, X1
Liang, W1
Hong, Z1
Bharathi, DV1
Hotha, KK1
Jagadeesh, B1
Chatki, PK1
Thriveni, K1
Mullangi, R1
Naidu, A1
Challa, BR1
Boddu, SH1
Awen, BZ1
Chandu, BR1
Bannoth, CK1
Khagga, M1
Kanala, K1
Shaik, RP1
Masaany, M1
Marina, MB1
Sharifa Ezat, WP1
Sani, A1
Barreiro, JC1
Vanzolini, KL1
Cass, QB2
Venugopal, N1
Bhaskar Reddy, AV1
Gangadhar Reddy, K1
Madhavi, V1
Madhavi, G1
Chen, M1
Xia, Y1
Ma, Z1
Li, L1
Zhong, D1
Chen, X1
Dulbecco, P1
Gambaro, C1
Bilardi, C1
Zentilin, P1
Mele, MR1
Mansi, C1
Biagini, R1
Tessieri, L1
Iiritano, E1
Usai, P1
Vigneri, S1
Savarino, V1
Plante, L1
Ferron, GM1
Unruh, M1
Mayer, PR1
Ramakrishna, NV1
Vishwottam, KN1
Wishu, S1
Koteshwara, M1
Raffin, RP1
Colomé, LM1
Pohlmann, AR1
Guterres, SS1
Rahman, N1
Bano, Z1
Azmi, SN1
Sivakumar, T1
Manavalan, R1
Muralidharan, C1
Valliappan, K1
Reddy, VR1
Rajmohan, MA1
Shilpa, RL1
Raut, DM1
Naveenkumar, K1
Suryanarayana, MV1
Mathad, VT1
Glatzel, D1
Abdel-Qader, M1
Gatz, G1
Pfaffenberger, B1
Guan, J1
Yang, J1
Bi, Y1
Shi, S1
Yan, F1
Li, F1
Degani, AL1
Cassiano, NM1
Pedrazolli, J1
Parente, F1
Sainaghi, M1
Sangaletti, O1
Imbesi, V1
Maconi, G1
Anderloni, A1
Bianchi Porro, G1

Trials

3 trials available for pantoprazole and Sensitivity and Specificity

ArticleYear
Impact of long-term ranitidine and pantoprazole on accuracy of [13C]urea breath test.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzimidazoles; Breath Tests; Dose-Response Relations

2003
Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse.
    Digestion, 2007, Volume: 75 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Cross-Over Studies; Dose-Response Relationship

2007
Different effects of short-term omeprazole, lansoprazole or pantoprazole on the accuracy of the (13)C-urea breath test.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Breath Tests; Car

2002

Other Studies

16 other studies available for pantoprazole and Sensitivity and Specificity

ArticleYear
Development and validation of new spectrophotometric ratio H-point standard addition method and application to gastrointestinal acting drugs mixtures.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, May-15, Volume: 109

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzamides; Benzyl Compounds; Gastrointestinal Agents; Morp

2013
High-Throughput Chiral LC-MS/MS Method Using Overlapping Injection Mode for the Determination of Pantoprazole Enantiomers in Human Plasma with Application to Pharmacokinetic Study.
    Chirality, 2016, Volume: 28, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Chromatography, Liquid; Drug Stability; High-Through

2016
Simultaneous estimation of four proton pump inhibitors--lansoprazole, omeprazole, pantoprazole and rabeprazole: development of a novel generic HPLC-UV method and its application to clinical pharmacokinetic study.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chromatography, High Pressure Liquid; Drug Stability; Human

2009
Development and validation of a sensitive bioanalytical method for the quantitative estimation of pantoprazole in human plasma samples by LC-MS/MS: application to bioequivalence study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Jun-01, Volume: 878, Issue:19

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Analysis of Variance; Area Under Curve; Chromatography, Liq

2010
Empirical treatment with pantoprazole as a diagnostic tool for symptomatic adult laryngopharyngeal reflux.
    The Journal of laryngology and otology, 2011, Volume: 125, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Body Mass Index; Double-Blind Method; En

2011
Direct injection of native aqueous matrices by achiral-chiral chromatography ion trap mass spectrometry for simultaneous quantification of pantoprazole and lansoprazole enantiomers fractions.
    Journal of chromatography. A, 2011, May-20, Volume: 1218, Issue:20

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Humic Substances; Lansoprazole; Least-Squares Analysis; Pan

2011
Method development and validation study for quantitative determination of 2-chloromethyl-3,4-dimethoxy pyridine hydrochloride a genotoxic impurity in pantoprazole active pharmaceutical ingredient (API) by LC/MS/MS.
    Journal of pharmaceutical and biomedical analysis, 2012, Volume: 70

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetonitriles; Buffers; Calibration; Chromatograp

2012
Validation of a chiral liquid chromatography-tandem mass spectrometry method for the determination of pantoprazole in dog plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Oct-01, Volume: 906

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Chromatography, Liquid; Dogs; Drug Stability; Line

2012
Excretion of pantoprazole in human breast.
    The Journal of reproductive medicine, 2004, Volume: 49, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Biological Transport, Active; Breast

2004
High-performance liquid chromatography method for the quantification of pantoprazole in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Aug-05, Volume: 822, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Chromatography, High Pressure Liquid; Human

2005
Preparation, characterization, and in vivo anti-ulcer evaluation of pantoprazole-loaded microparticles.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2006, Volume: 63, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Calorimetry, Di

2006
Kinetic spectrophotometric analysis of pantoprazole in commercial dosage forms.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2006, Volume: 22, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ferricyanides; Ferrocyanides; Hydrogen-Ion Concentration; I

2006
Multi-criteria decision making approach and experimental design as chemometric tools to optimize HPLC separation of domperidone and pantoprazole.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetonitriles; Analysis of Variance; Anti-Ulcer Agents; Cal

2007
A novel quantification method of pantaprazole sodium monohydrate in sesquihydrate by thermogravimetric analyzer.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Calibration; Calorimetry, Differential S

2007
Determination of the enantiomeric impurity in S-(-)pantoprazole using high performance liquid chromatography with sulfobutylether-beta-cyclodextrin as chiral additive.
    Journal of separation science, 2008, Volume: 31, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; beta-Cyclodextrins; Chromatography, High

2008
Enantiomeric determination of pantoprazole in human plasma by multidimensional high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Jan-05, Volume: 766, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Calibration; Chromatography, High Pressure

2002