Page last updated: 2024-12-05

4-azaindole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

4-Azaindole is a heterocyclic compound containing a fused pyrrole and pyridine ring system. It has been investigated for its potential pharmacological properties, including its ability to act as a serotonin receptor agonist and an inhibitor of the enzyme monoamine oxidase. 4-Azaindole is also a key building block in the synthesis of various natural products and pharmaceutical compounds. Due to its unique structural features and biological activities, 4-azaindole has attracted significant attention from synthetic organic chemists and medicinal chemists. Research on 4-azaindole focuses on exploring its diverse applications in drug discovery and development, materials science, and organic synthesis.'

Cross-References

ID SourceID
PubMed CID9226
CHEMBL ID5184883
SCHEMBL ID12565
SCHEMBL ID17850816
SCHEMBL ID16662494
MeSH IDM0513486

Synonyms (38)

Synonym
AC-088 ,
1,4-diazaindene
1h-pyrrolo(3,2-b)pyridine
BB 0260112
4-azaindole ,
272-49-1
A-9485
brn 0109683
1h-pyrrolo[3,2-b]pyridine
AKOS005256883
pyrrolopyridine
5-23-06-00303 (beilstein handbook reference)
FT-0601479
PS-4925
AM20051025
4jp ,
PB18523
SCHEMBL12565
mfcd00971977
SY019307
pyrrolo[3,2-b]pyridine
XWIYUCRMWCHYJR-UHFFFAOYSA-N
W-204756
4-azaindole;4-azaindole
P2041
SCHEMBL17850816
DTXSID00181666
1h-pyrrolo[3,2-b]pyridine, aldrichcpr
Z1925930568
SCHEMBL16662494
CS-D1166
CHEMBL5184883
BBL103666
STL557476
BCP26719
Q27454752
EN300-94605
HY-20362
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1891830Basic dissociation constant, pKa of the compound2022Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives.
AID1891831Lipid-water distribution ratio of the compound2022Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (18)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's13 (72.22)24.3611
2020's1 (5.56)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.81

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.81 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.83 (4.65)
Search Engine Demand Index24.97 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.81)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (5.56%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other17 (94.44%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]