Oxysterol-binding protein 2

An oxysterol-binding protein 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q969R2]

Oxysterol-binding protein-related protein 4;
ORP-4;
OSBP-related protein 4

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
25-hydroxycholesterol	Homo sapiens (human)	Kd	0.0200	1	2

This protein enables 2 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
cholesterol binding	molecular function	Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:jl, ISBN:0198506732]

This protein is located in 1 target(s):

Target	Category	Definition
apical dendrite	cellular component	A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon. [NIF_Subcellular:sao273773228]

This protein is active in 3 target(s):

Target	Category	Definition
cytosol	cellular component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
perinuclear endoplasmic reticulum	cellular component	The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes. [GOC:bf, GOC:mah, GOC:mcc, GOC:pr, GOC:vw]

This protein is involved in 2 target(s):

Target	Category	Definition
lipid transport	biological process	The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [ISBN:0198506732]
spermatid development	biological process	The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. [GOC:dph, GOC:go_curators]