Page last updated: 2024-08-07 17:12:24
Genome polyprotein
[no definition available]
Synonyms
Research
Bioassay Publications (14)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (64.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (25)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pleconaril | Human rhinovirus sp. | CC50 | 10.0000 | 1 | 1 |
| pirodavir | Human rhinovirus sp. | CC50 | 10.0000 | 1 | 1 |
| rupintrivir | Human rhinovirus sp. | EC90 | 0.0478 | 4 | 4 |
Protease inhibitors: current status and future prospects.Journal of medicinal chemistry, , Feb-10, Volume: 43, Issue:3, 2000
Potent HIV protease inhibitors containing a novel (hydroxyethyl)amide isostere.Journal of medicinal chemistry, , Jul-04, Volume: 40, Issue:14, 1997
Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors.Journal of medicinal chemistry, , Jun-15, Volume: 49, Issue:12, 2006
Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease.Journal of medicinal chemistry, , Dec-20, Volume: 39, Issue:26, 1996
Structural variations in keto-glutamines for improved inhibition against hepatitis A virus 3C proteinase.Bioorganic & medicinal chemistry letters, , Jul-16, Volume: 14, Issue:14, 2004
Protease inhibitors: current status and future prospects.Journal of medicinal chemistry, , Feb-10, Volume: 43, Issue:3, 2000
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements.Journal of medicinal chemistry, , Apr-08, Volume: 42, Issue:7, 1999