Page last updated: 2024-08-07 13:18:35
Mitogen-activated protein kinase 14
A mitogen-activated protein kinase 14 that is encoded in the genome of mouse. [OMA:P47811, PRO:DNx]
Synonyms
MAP kinase 14;
MAPK 14;
EC 2.7.11.24;
CRK1;
Mitogen-activated protein kinase p38 alpha;
MAP kinase p38 alpha
Research
Bioassay Publications (6)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (6)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| sb 203580 | Mus musculus (house mouse) | IC50 | 0.0560 | 1 | 3 |
| vx-745 | Mus musculus (house mouse) | IC50 | 0.0442 | 2 | 4 |
| rwj 68354 | Mus musculus (house mouse) | IC50 | 1.5000 | 1 | 1 |
| 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide | Mus musculus (house mouse) | IC50 | 0.3300 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| birb 796 | Mus musculus (house mouse) | Kd | 0.0001 | 3 | 3 |
| sb 203580 | Mus musculus (house mouse) | Kd | 0.0200 | 2 | 2 |
| 1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea | Mus musculus (house mouse) | Kd | 1.1600 | 1 | 1 |