Proteins > UDP-glucuronosyltransferase 2B15
Page last updated: 2024-08-07 23:36:50

UDP-glucuronosyltransferase 2B15

A UDP-glucuronosyltransferase 2B15 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P54855]

Synonyms

UDPGT 2B15;
UGT2B15;
EC 2.4.1.17;
HLUG4;
UDP-glucuronosyltransferase 2B8;
UDPGT 2B8;
UDPGTh-3

Research

Bioassay Publications (2)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Compounds (7)

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
ezogabineHomo sapiens (human)EC503.900011

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
sn 38Homo sapiens (human)Km186.000011
5 alpha-androstane-3 beta,17 beta-diolHomo sapiens (human)Km15.000011
alpha-hydroxytamoxifenHomo sapiens (human)Km12.500012
tolcaponeHomo sapiens (human)Km429.000011
entacaponeHomo sapiens (human)Km322.000011
5-hydroxyrofecoxibHomo sapiens (human)Km286.000011

Enables

This protein enables 1 target(s):

TargetCategoryDefinition
glucuronosyltransferase activitymolecular functionCatalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. [RHEA:21032]

Located In

This protein is located in 1 target(s):

TargetCategoryDefinition
endoplasmic reticulum membranecellular componentThe lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah]

Involved In

This protein is involved in 4 target(s):

TargetCategoryDefinition
xenobiotic metabolic processbiological processThe chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc]
steroid metabolic processbiological processThe chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. [ISBN:0198547684]
estrogen metabolic processbiological processThe chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. [ISBN:0198506732]
cellular glucuronidationbiological processThe modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor. [GOC:BHF]