| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Cancer of Kidney
[description not available] | 0 | 5.1 | 3 | 1 |
Kidney Neoplasms
Tumors or cancers of the KIDNEY. | 0 | 5.1 | 3 | 1 |
Neuroendocrine Tumors
Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition. | 0 | 20.75 | 265 | 76 |
Cancer of Pancreas
[description not available] | 0 | 16.06 | 76 | 15 |
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 16.06 | 76 | 15 |
Cancer of Liver
[description not available] | 0 | 11.24 | 27 | 6 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 11.24 | 27 | 6 |
Liver Steatosis
[description not available] | 0 | 2.25 | 1 | 0 |
Fatty Liver
Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS. | 0 | 2.25 | 1 | 0 |
Cancer of Gastrointestinal Tract
[description not available] | 0 | 16.76 | 52 | 36 |
Cancer of Intestines
[description not available] | 0 | 10.09 | 31 | 2 |
Cancer of Stomach
[description not available] | 0 | 8.71 | 23 | 2 |
Intestinal Neoplasms
Tumors or cancer of the INTESTINES. | 0 | 10.09 | 31 | 2 |
Stomach Neoplasms
Tumors or cancer of the STOMACH. | 0 | 8.71 | 23 | 2 |
Response Evaluation Criteria in Solid Tumors
An internationally recognized set of published rules used for evaluation of cancer treatment that define when tumors found in cancer patients improve, worsen, or remain stable during treatment. These criteria are based specifically on the response of the tumor(s) to treatment, and not on the overall health status of the patient resulting from treatment. | 0 | 3.88 | 3 | 0 |
Benign Meningeal Neoplasms
[description not available] | 0 | 3.56 | 7 | 0 |
Angioblastic Meningioma
[description not available] | 0 | 3.75 | 9 | 0 |
Meningeal Neoplasms
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord. | 0 | 3.56 | 7 | 0 |
Meningioma
A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7) | 0 | 3.75 | 9 | 0 |
Disease Exacerbation
[description not available] | 0 | 10.46 | 22 | 4 |
Cancer of Prostate
[description not available] | 0 | 2.91 | 3 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.91 | 3 | 0 |
Recrudescence
[description not available] | 0 | 2.81 | 3 | 0 |
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 4.8 | 6 | 0 |
Glial Cell Tumors
[description not available] | 0 | 2.31 | 1 | 0 |
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 2.31 | 1 | 0 |
Adrenal Cancer
[description not available] | 0 | 2.86 | 3 | 0 |
Paraganglioma, Gangliocytic
[description not available] | 0 | 4.94 | 12 | 0 |
Pheochromocytoma, Extra-Adrenal
[description not available] | 0 | 4.68 | 5 | 0 |
Paraganglioma
A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992) | 0 | 4.94 | 12 | 0 |
Pheochromocytoma
A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298) | 0 | 4.68 | 5 | 0 |
Cancer of Mediastinum
[description not available] | 0 | 2.82 | 3 | 0 |
Metastase
[description not available] | 0 | 10.29 | 39 | 3 |
Mediastinal Neoplasms
Tumors or cancer of the MEDIASTINUM. | 0 | 2.82 | 3 | 0 |
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 10.29 | 39 | 3 |
Benign Neoplasms
[description not available] | 0 | 8.44 | 16 | 0 |
Injuries, Radiation
[description not available] | 0 | 12.1 | 17 | 6 |
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues. | 0 | 8.57 | 9 | 5 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 8.44 | 16 | 0 |
Cancer of Lung
[description not available] | 0 | 8.2 | 15 | 1 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 8.2 | 15 | 1 |
Coagulation, Disseminated Intravascular
[description not available] | 0 | 2.31 | 1 | 0 |
Bleeding
[description not available] | 0 | 2.31 | 1 | 0 |
Cancer of ILEUM
[description not available] | 0 | 4.12 | 5 | 0 |
Disseminated Intravascular Coagulation
A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS. | 0 | 2.31 | 1 | 0 |
Hemorrhage
Bleeding or escape of blood from a vessel. | 0 | 2.31 | 1 | 0 |
Cancer of Digestive System
[description not available] | 0 | 6.84 | 4 | 2 |
Digestive System Neoplasms
Tumors or cancer of the DIGESTIVE SYSTEM. | 0 | 6.84 | 4 | 2 |
Cancer of the Thyroid
[description not available] | 0 | 7.78 | 12 | 2 |
Local Neoplasm Recurrence
[description not available] | 0 | 5.68 | 6 | 1 |
Thyroid Neoplasms
Tumors or cancer of the THYROID GLAND. | 0 | 7.78 | 12 | 2 |
Cerebral Primitive Neuroectodermal Tumor
[description not available] | 0 | 3.44 | 2 | 0 |
Neuroectodermal Tumors, Primitive
A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059) | 0 | 3.44 | 2 | 0 |
Soft Tissue Neoplasms
Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc. | 0 | 2.57 | 2 | 0 |
Androgen-Independent Prostatic Cancer
[description not available] | 0 | 2.93 | 3 | 0 |
Prostatic Neoplasms, Castration-Resistant
Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE. | 0 | 2.93 | 3 | 0 |
Cancer of the Thymus
[description not available] | 0 | 2.57 | 2 | 0 |
Neoplasms, Bone Marrow
[description not available] | 0 | 2.25 | 1 | 0 |
Thymus Neoplasms
Tumors or cancer of the THYMUS GLAND. | 0 | 2.57 | 2 | 0 |
Bone Marrow Neoplasms
Neoplasms located in the bone marrow. They are differentiated from neoplasms composed of bone marrow cells, such as MULTIPLE MYELOMA. Most bone marrow neoplasms are metastatic. | 0 | 2.25 | 1 | 0 |
Carcinoma, Neuroendocrine
A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round blue cells, granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small (oat) cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992) | 0 | 8.33 | 13 | 1 |
Adult Fanconi Syndrome
[description not available] | 0 | 2.21 | 1 | 0 |
Bone Cancer
[description not available] | 0 | 7.17 | 11 | 1 |
Cardiac Cancer
[description not available] | 0 | 3.12 | 4 | 0 |
Lymph Node Metastasis
[description not available] | 0 | 2.25 | 1 | 0 |
Cancer of Rectum
[description not available] | 0 | 2.93 | 3 | 0 |
Bone Neoplasms
Tumors or cancer located in bone tissue or specific BONES. | 0 | 7.17 | 11 | 1 |
Rectal Neoplasms
Tumors or cancer of the RECTUM. | 0 | 2.93 | 3 | 0 |
Carcinoid Heart Disease
Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation. | 0 | 2.89 | 3 | 0 |
Peritoneal Diseases
Pathological processes involving the PERITONEUM. | 0 | 2.31 | 1 | 0 |
Intestinal Obstruction
Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL. | 0 | 2.31 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 4.61 | 3 | 0 |
Infections, Coronavirus
[description not available] | 0 | 2.25 | 1 | 0 |
Respiratory Syndrome, Acute, Severe
[description not available] | 0 | 2.25 | 1 | 0 |
2019 Novel Coronavirus Disease
[description not available] | 0 | 2.25 | 1 | 0 |
Pneumonia, Viral
Inflammation of the lung parenchyma that is caused by a viral infection. | 0 | 2.25 | 1 | 0 |
Coronavirus Infections
Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE). | 0 | 2.25 | 1 | 0 |
Severe Acute Respiratory Syndrome
A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent. | 0 | 2.25 | 1 | 0 |
Endothelioma, Vascular
[description not available] | 0 | 2.25 | 1 | 0 |
Hemangioendothelioma
A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866) | 0 | 2.25 | 1 | 0 |
Cancer of Head
[description not available] | 0 | 2.81 | 3 | 0 |
Head and Neck Neoplasms
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 2.81 | 3 | 0 |
Neoplasms, Bronchial
[description not available] | 0 | 4.65 | 3 | 0 |
Argentaffinoma
[description not available] | 0 | 12 | 20 | 10 |
Bronchial Neoplasms
Tumors or cancer of the BRONCHI. | 0 | 4.65 | 3 | 0 |
Carcinoid Tumor
A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182) | 0 | 12 | 20 | 10 |
Asystole
[description not available] | 0 | 2.25 | 1 | 0 |
Heart Arrest
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation. | 0 | 2.25 | 1 | 0 |
Cardiac Toxicity
[description not available] | 0 | 2.63 | 2 | 0 |
Cardiotoxicity
Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION. | 0 | 2.63 | 2 | 0 |
Adenoma, Basal Cell
[description not available] | 0 | 3.42 | 2 | 0 |
Cancer of Pituitary
[description not available] | 0 | 3.94 | 4 | 0 |
Adenoma
A benign epithelial tumor with a glandular organization. | 0 | 3.42 | 2 | 0 |
Pituitary Neoplasms
Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA. | 0 | 3.94 | 4 | 0 |
Emesis
[description not available] | 0 | 5.07 | 3 | 1 |
Nausea
An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses. | 0 | 12.87 | 28 | 26 |
Vomiting
The forcible expulsion of the contents of the STOMACH through the MOUTH. | 0 | 5.07 | 3 | 1 |
Diarrheogenic Islet Cell Tumor
[description not available] | 0 | 2.31 | 1 | 0 |
Diarrhea
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. | 0 | 2.31 | 1 | 0 |
Malignant Carcinoid Syndrome
A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed) | 0 | 2.31 | 1 | 0 |
Kidney Failure
A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. | 0 | 4.86 | 2 | 1 |
Blood Diseases
[description not available] | 0 | 10.76 | 11 | 9 |
Hematologic Diseases
Disorders of the blood and blood forming tissues. | 0 | 10.76 | 11 | 9 |
Renal Insufficiency
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. | 0 | 4.86 | 2 | 1 |
Ascites
Accumulation or retention of free fluid within the peritoneal cavity. | 0 | 4.9 | 2 | 1 |
Leucocythaemia
[description not available] | 0 | 2.15 | 1 | 0 |
Dysmyelopoietic Syndromes
[description not available] | 0 | 9.76 | 10 | 9 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 2.15 | 1 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.15 | 1 | 0 |
Myelodysplastic Syndromes
Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA. | 0 | 9.76 | 10 | 9 |
Familial Hypokalemia-Hypomagnesemia
[description not available] | 0 | 2.15 | 1 | 0 |
Metabolic Acidosis
[description not available] | 0 | 2.15 | 1 | 0 |
Hypokalemia
Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed) | 0 | 2.53 | 2 | 0 |
Water-Electrolyte Imbalance
Disturbances in the body's WATER-ELECTROLYTE BALANCE. | 0 | 2.15 | 1 | 0 |
Acidosis
A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up. | 0 | 2.15 | 1 | 0 |
Hypocalcemia
Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed) | 0 | 3.9 | 2 | 1 |
Granuloma, Hodgkin
[description not available] | 0 | 3.09 | 1 | 0 |
Hodgkin Disease
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen. | 0 | 3.09 | 1 | 0 |
Thyroid Diseases
Pathological processes involving the THYROID GLAND. | 0 | 3.09 | 1 | 0 |
Acute Edematous Pancreatitis
[description not available] | 0 | 2.17 | 1 | 0 |
Pancreatitis
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. | 0 | 2.17 | 1 | 0 |
Cardiovascular Stroke
[description not available] | 0 | 2.17 | 1 | 0 |
Dysembryoma
[description not available] | 0 | 2.17 | 1 | 0 |
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 2.17 | 1 | 0 |
Teratoma
A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642) | 0 | 2.17 | 1 | 0 |
Adenoma, beta-Cell
[description not available] | 0 | 3.96 | 4 | 0 |
Insulinoma
A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA. | 0 | 3.96 | 4 | 0 |
Diverticulum, Meckel
[description not available] | 0 | 2.17 | 1 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 2.21 | 1 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 2.21 | 1 | 0 |
Multiple Endocrine Neoplasia Type 1
A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13). | 0 | 2.21 | 1 | 0 |
Single Functioning Kidney
[description not available] | 0 | 2.21 | 1 | 0 |
Tachyarrhythmia
[description not available] | 0 | 2.21 | 1 | 0 |
Tachycardia
Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia. | 0 | 2.21 | 1 | 0 |
B-Cell Chronic Lymphocytic Leukemia
[description not available] | 0 | 2.21 | 1 | 0 |
Leukemia, Lymphocytic, Chronic, B-Cell
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease. | 0 | 2.21 | 1 | 0 |
Merkel Cell Cancer
[description not available] | 0 | 3.48 | 2 | 0 |
Carcinoma, Merkel Cell
A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245) | 0 | 3.48 | 2 | 0 |
Orbital Neoplasms
Neoplasms of the bony orbit and contents except the eyeball. | 0 | 2.51 | 2 | 0 |
Osseous Paget's Disease
[description not available] | 0 | 2.08 | 1 | 0 |
Osteitis Deformans
A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry. | 0 | 2.08 | 1 | 0 |
Thoracic Neoplasms
New abnormal growth of tissue in the THORAX. | 0 | 2.08 | 1 | 0 |
Carotid Body Tumor
Benign paraganglioma at the bifurcation of the COMMON CAROTID ARTERIES. It can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies. | 0 | 2.1 | 1 | 0 |
Spinal Neoplasms
New abnormal growth of tissue in the SPINE. | 0 | 2.1 | 1 | 0 |
Acromegaly Due To Pituitary Adenoma
[description not available] | 0 | 2.1 | 1 | 0 |
Adenoma, Prolactin-Secreting, Pituitary
[description not available] | 0 | 2.1 | 1 | 0 |
Carcinoma, Oat Cell
[description not available] | 0 | 2.95 | 4 | 0 |
Carcinoma, Small Cell Lung
[description not available] | 0 | 2.11 | 1 | 0 |
Carcinoma, Small Cell
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) | 0 | 2.95 | 4 | 0 |
Small Cell Lung Carcinoma
A form of highly malignant lung cancer that is composed of small ovoid cells (SMALL CELL CARCINOMA). | 0 | 2.11 | 1 | 0 |
Cancer of Duodenum
[description not available] | 0 | 2.47 | 2 | 0 |
Carcinoma, Anaplastic
[description not available] | 0 | 5.07 | 3 | 1 |
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 5.07 | 3 | 1 |
Peritoneal Carcinomatosis
[description not available] | 0 | 2.11 | 1 | 0 |
Peritoneal Neoplasms
Tumors or cancer of the PERITONEUM. | 0 | 2.11 | 1 | 0 |
Neurocytoma
A benign brain tumor composed of neural elements which most often arise from the SEPTUM PELLUCIDUM and the walls of the lateral ventricles. Immunohistochemistry and electron microscopy evaluations may reveal expression of neuron specific enolase and synaptophysin and cells containing microtubuli, neurosecretory granules, and presynaptic vesicles. (From Acta Med Port 1994 Feb;7(2):113-9) | 0 | 2.11 | 1 | 0 |
Rhabdoid Tumor
A rare but highly lethal childhood tumor found almost exclusively in infants. Histopathologically, it resembles RHABDOMYOSARCOMA but the tumor cells are not of myogenic origin. Although it arises primarily in the kidney, it may be found in other parts of the body. The rhabdoid cytomorphology is believed to be the expression of a very primitive malignant cell. (From Holland et al., Cancer Medicine, 3d ed, p2210) | 0 | 2.11 | 1 | 0 |
Aesthesioneuroblastoma
[description not available] | 0 | 2.11 | 1 | 0 |
Cancer of Nose
[description not available] | 0 | 2.11 | 1 | 0 |
Esthesioneuroblastoma, Olfactory
A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33) | 0 | 2.11 | 1 | 0 |
Ache
[description not available] | 0 | 3.02 | 4 | 0 |
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 3.02 | 4 | 0 |
Breast Cancer
[description not available] | 0 | 2.13 | 1 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 2.13 | 1 | 0 |
Carcinoma, Thymic
[description not available] | 0 | 2.11 | 1 | 0 |
Thymoma
A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed) | 0 | 2.11 | 1 | 0 |
Adenoma, alpha-Cell
[description not available] | 0 | 2.11 | 1 | 0 |
Adenocarcinoma, Basal Cell
[description not available] | 0 | 3.03 | 1 | 0 |
Adenocarcinoma
A malignant epithelial tumor with a glandular organization. | 0 | 3.03 | 1 | 0 |
Aldosteronism
[description not available] | 0 | 2.11 | 1 | 0 |
Hyperaldosteronism
A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA. | 0 | 2.11 | 1 | 0 |
Cancer of Skin
[description not available] | 0 | 3.04 | 1 | 0 |
Skin Neoplasms
Tumors or cancer of the SKIN. | 0 | 3.04 | 1 | 0 |
Astrocytoma, Grade IV
[description not available] | 0 | 2.13 | 1 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.13 | 1 | 0 |
Familial Nonmedullary Thyroid Cancer
[description not available] | 0 | 2.13 | 1 | 0 |
Carcinoma, Papillary
A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed) | 0 | 2.13 | 1 | 0 |
Nodular Goiter
[description not available] | 0 | 2.13 | 1 | 0 |
Goiter, Nodular
An enlarged THYROID GLAND containing multiple nodules (THYROID NODULE), usually resulting from recurrent thyroid HYPERPLASIA and involution over many years to produce the irregular enlargement. Multinodular goiters may be nontoxic or may induce THYROTOXICOSIS. | 0 | 2.13 | 1 | 0 |
Complications of Diabetes Mellitus
[description not available] | 0 | 3.53 | 1 | 1 |
Lymphocytopenia
[description not available] | 0 | 3.53 | 1 | 1 |
Thrombopenia
[description not available] | 0 | 3.53 | 1 | 1 |
Lymphopenia
Reduction in the number of lymphocytes. | 0 | 3.53 | 1 | 1 |
Thrombocytopenia
A subnormal level of BLOOD PLATELETS. | 0 | 3.53 | 1 | 1 |
Besnier-Boeck Disease
[description not available] | 0 | 2.13 | 1 | 0 |
Sarcoidosis
An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands. | 0 | 2.13 | 1 | 0 |
Acute Kidney Failure
[description not available] | 0 | 2.15 | 1 | 0 |
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 2.15 | 1 | 0 |
Cancer of Colon
[description not available] | 0 | 2.05 | 1 | 0 |
Colonic Neoplasms
Tumors or cancer of the COLON. | 0 | 2.05 | 1 | 0 |
Fasting Hypoglycemia
HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast. | 0 | 2.05 | 1 | 0 |
Hypoglycemia
A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. | 0 | 2.05 | 1 | 0 |
Proteinuria
The presence of proteins in the urine, an indicator of KIDNEY DISEASES. | 0 | 2.45 | 2 | 0 |
Carcinoma, Medullary
A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992) | 0 | 2.06 | 1 | 0 |
Anorexia
The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA. | 0 | 2.06 | 1 | 0 |
Neuroectodermal Tumors
Malignant neoplasms arising in the neuroectoderm, the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems, including some glial cells. | 0 | 2.07 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 2.46 | 2 | 0 |
Cancer of Ovary
[description not available] | 0 | 2.07 | 1 | 0 |
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 2.07 | 1 | 0 |
Alopecia Cicatrisata
[description not available] | 0 | 4.31 | 1 | 1 |
Colicky Pain
[description not available] | 0 | 4.31 | 1 | 1 |
Alopecia
Absence of hair from areas where it is normally present. | 0 | 4.31 | 1 | 1 |
Abdominal Pain
Sensation of discomfort, distress, or agony in the abdominal region. | 0 | 4.31 | 1 | 1 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.71 | 3 | 0 |
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 4.32 | 1 | 1 |
Cancer of Endocrine Gland
[description not available] | 0 | 4.73 | 2 | 1 |
Island Cell Tumor
[description not available] | 0 | 4.32 | 1 | 1 |
Endocrine Gland Neoplasms
Tumors or cancer of the ENDOCRINE GLANDS. | 0 | 4.73 | 2 | 1 |
Adenoma, Islet Cell
A benign tumor of the pancreatic ISLET CELLS. Usually it involves the INSULIN-producing PANCREATIC BETA CELLS, as in INSULINOMA, resulting in HYPERINSULINISM. | 0 | 4.32 | 1 | 1 |
Experimental Neoplasms
[description not available] | 0 | 2.02 | 1 | 0 |
Bone Marrow Diseases
Diseases involving the BONE MARROW. | 0 | 2.03 | 1 | 0 |
Diplopia
A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE. | 0 | 2.96 | 1 | 0 |
Bilateral Headache
[description not available] | 0 | 2.96 | 1 | 0 |
Headache
The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS. | 0 | 2.96 | 1 | 0 |
Diseases of Endocrine System
[description not available] | 0 | 2.96 | 1 | 0 |
Endocrine System Diseases
Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES. | 0 | 2.96 | 1 | 0 |
Cushing's Syndrome
[description not available] | 0 | 2.04 | 1 | 0 |
Gastrin-Producing Tumor
[description not available] | 0 | 2.04 | 1 | 0 |
Cushing Syndrome
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent. | 0 | 2.04 | 1 | 0 |
Gastrinoma
A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1). | 0 | 2.04 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 9.65 | 9 | 9 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 9.65 | 9 | 9 |
Allergy, Drug
[description not available] | 0 | 2.04 | 1 | 0 |
Drug Hypersensitivity
Immunologically mediated adverse reactions to medicinal substances used legally or illegally. | 0 | 2.04 | 1 | 0 |