Page last updated: 2024-08-07 16:42:50
P2X purinoceptor 1
A P2X purinoceptor 1 that is encoded in the genome of rat. [OMA:P47824, PRO:DNx]
Synonyms
P2X1;
ATP receptor;
Purinergic receptor;
RP-2 protein
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
Compounds (14)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid | Rattus norvegicus (Norway rat) | IC50 | 33.1997 | 3 | 3 |
| mrs2159 | Rattus norvegicus (Norway rat) | IC50 | 0.0262 | 2 | 2 |
| nf 449 | Rattus norvegicus (Norway rat) | IC50 | 0.0003 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| pyridoxal phosphate | Rattus norvegicus (Norway rat) | EC50 | 3.0000 | 1 | 1 |
| pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid | Rattus norvegicus (Norway rat) | EC50 | 0.0990 | 1 | 1 |
| suramin | Rattus norvegicus (Norway rat) | EC50 | 1.0000 | 1 | 1 |
| adenosine diphosphate | Rattus norvegicus (Norway rat) | EC50 | 10.0000 | 1 | 1 |
| diadenosine tetraphosphate | Rattus norvegicus (Norway rat) | EC50 | 0.1820 | 1 | 1 |
| 5'-adenylyl (beta,gamma-methylene)diphosphonate | Rattus norvegicus (Norway rat) | EC50 | 2.0000 | 1 | 1 |
| alpha,beta-methyleneadenosine 5'-triphosphate | Rattus norvegicus (Norway rat) | EC50 | 0.2000 | 1 | 1 |
| adenosine 5'-o-(3-thiotriphosphate) | Rattus norvegicus (Norway rat) | EC50 | 2.3000 | 1 | 1 |
| mrs 2219 | Rattus norvegicus (Norway rat) | EC50 | 7.3333 | 3 | 3 |
| 2-methylthio-atp | Rattus norvegicus (Norway rat) | EC50 | 0.0540 | 1 | 1 |
| adp beta s | Rattus norvegicus (Norway rat) | EC50 | 2.5000 | 1 | 1 |
| acid blue 129 | Rattus norvegicus (Norway rat) | Kd | 100.0000 | 1 | 1 |