Proteins > Group IIE secretory phospholipase A2
Page last updated: 2024-08-07 19:36:03
Group IIE secretory phospholipase A2
A group IIE secretory phospholipase A2 that is encoded in the genome of mouse. [OMA:Q9QUL3, PRO:DNx]
Synonyms
GIIE sPLA2;
sPLA2-IIE;
EC 3.1.1.4;
Phosphatidylcholine 2-acylhydrolase 2E
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| varespladib | Mus musculus (house mouse) | IC50 | 0.0750 | 2 | 2 |
| indoxam | Mus musculus (house mouse) | IC50 | 0.0350 | 1 | 1 |
Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2.Journal of medicinal chemistry, , Aug-14, Volume: 51, Issue:15, 2008
The first potent inhibitor of mammalian group X secreted phospholipase A2: elucidation of sites for enhanced binding.Journal of medicinal chemistry, , May-18, Volume: 49, Issue:10, 2006