mecamylamine has been researched along with Sensitivity and Specificity in 3 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This method is useful for monitoring mecamylamine, nicotine and nicotine metabolites in smoking cessation and other clinical nicotine research." | 3.78 | Simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine, norcotinine and mecamylamine in human urine by liquid chromatography-tandem mass spectrometry. ( Huestis, MA; Scheidweiler, KB; Shakleya, DM, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scheidweiler, KB | 1 |
| Shakleya, DM | 1 |
| Huestis, MA | 1 |
| Khan, IM | 1 |
| Taylor, P | 1 |
| Yaksh, TL | 1 |
| Webster, JC | 1 |
| Francis, MM | 1 |
| Porter, JK | 1 |
| Robinson, G | 1 |
| Stokes, C | 1 |
| Horenstein, B | 1 |
| Papke, RL | 1 |
3 other studies available for mecamylamine and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine, norcotinine and mecamylamine in human urine by liquid chromatography-tandem mass spectrometry.
Topics: Calibration; Chromatography, Liquid; Cotinine; Humans; Mecamylamine; Nicotine; Sensitivity and Speci | 2012 |
Cardiovascular and behavioral responses to nicotinic agents administered intrathecally.
Topics: Aconitine; Alkaloids; Animals; Atropine; Azocines; Behavior, Animal; Blood Pressure; Bungarotoxins; | 1994 |
Antagonist activities of mecamylamine and nicotine show reciprocal dependence on beta subunit sequence in the second transmembrane domain.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiol | 1999 |