A protein that is a translation product of the Glra2 gene in rat. [PRO:DNx, UniProtKB:P22771]
Glycine receptor strychnine-binding subunit
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| clotrimazole | Rattus norvegicus (Norway rat) | IC50 | 3.2580 | 1 | 0 |
| clotrimazole | Rattus norvegicus (Norway rat) | Ki | 1.4810 | 1 | 0 |
| cortisone acetate | Rattus norvegicus (Norway rat) | IC50 | 3.9110 | 1 | 0 |
| cortisone acetate | Rattus norvegicus (Norway rat) | Ki | 1.7780 | 1 | 0 |
| prednisolone | Rattus norvegicus (Norway rat) | IC50 | 0.0160 | 1 | 0 |
| prednisolone | Rattus norvegicus (Norway rat) | Ki | 0.0074 | 1 | 0 |
| estriol | Rattus norvegicus (Norway rat) | IC50 | 39.3450 | 1 | 0 |
| estriol | Rattus norvegicus (Norway rat) | Ki | 17.8840 | 1 | 0 |
| norethindrone acetate | Rattus norvegicus (Norway rat) | IC50 | 0.6460 | 1 | 0 |
| norethindrone acetate | Rattus norvegicus (Norway rat) | Ki | 0.2930 | 1 | 0 |
| spironolactone | Rattus norvegicus (Norway rat) | IC50 | 1.9025 | 1 | 0 |
| spironolactone | Rattus norvegicus (Norway rat) | Ki | 0.8648 | 1 | 0 |
| prednisone | Rattus norvegicus (Norway rat) | IC50 | 1.1460 | 1 | 0 |
| prednisone | Rattus norvegicus (Norway rat) | Ki | 0.5210 | 1 | 0 |
| ethinyl estradiol | Rattus norvegicus (Norway rat) | IC50 | 1.7100 | 1 | 0 |
| ethinyl estradiol | Rattus norvegicus (Norway rat) | Ki | 0.7770 | 1 | 0 |
| methyltestosterone | Rattus norvegicus (Norway rat) | IC50 | 1.8430 | 1 | 0 |
| methyltestosterone | Rattus norvegicus (Norway rat) | Ki | 0.8380 | 1 | 0 |
| fluocinolone acetonide | Rattus norvegicus (Norway rat) | IC50 | 0.0031 | 1 | 0 |
| fluocinolone acetonide | Rattus norvegicus (Norway rat) | Ki | 0.0014 | 1 | 0 |
| norethindrone | Rattus norvegicus (Norway rat) | IC50 | 0.4330 | 1 | 0 |
| norethindrone | Rattus norvegicus (Norway rat) | Ki | 0.1970 | 1 | 0 |
| 17-alpha-hydroxyprogesterone | Rattus norvegicus (Norway rat) | IC50 | 0.0510 | 1 | 0 |
| 17-alpha-hydroxyprogesterone | Rattus norvegicus (Norway rat) | Ki | 0.0230 | 1 | 0 |
| medroxyprogesterone acetate | Rattus norvegicus (Norway rat) | IC50 | 0.0190 | 1 | 0 |
| medroxyprogesterone acetate | Rattus norvegicus (Norway rat) | Ki | 0.0086 | 1 | 0 |
| triamcinolone acetonide | Rattus norvegicus (Norway rat) | IC50 | 0.0044 | 1 | 0 |
| triamcinolone acetonide | Rattus norvegicus (Norway rat) | Ki | 0.0020 | 1 | 0 |
| methylprednisolone | Rattus norvegicus (Norway rat) | IC50 | 0.0110 | 1 | 0 |
| methylprednisolone | Rattus norvegicus (Norway rat) | Ki | 0.0050 | 1 | 0 |
| chlormadinone acetate | Rattus norvegicus (Norway rat) | IC50 | 0.0377 | 1 | 0 |
| chlormadinone acetate | Rattus norvegicus (Norway rat) | Ki | 0.0172 | 1 | 0 |
| fluocinonide | Rattus norvegicus (Norway rat) | IC50 | 0.0053 | 1 | 0 |
| fluocinonide | Rattus norvegicus (Norway rat) | Ki | 0.0024 | 1 | 0 |
| betamethasone | Rattus norvegicus (Norway rat) | IC50 | 0.0077 | 1 | 0 |
| betamethasone | Rattus norvegicus (Norway rat) | Ki | 0.0035 | 1 | 0 |
| fluorometholone | Rattus norvegicus (Norway rat) | IC50 | 0.0035 | 1 | 0 |
| fluorometholone | Rattus norvegicus (Norway rat) | Ki | 0.0016 | 1 | 0 |
| cyproterone acetate | Rattus norvegicus (Norway rat) | IC50 | 0.2250 | 1 | 0 |
| cyproterone acetate | Rattus norvegicus (Norway rat) | Ki | 0.1020 | 1 | 0 |
| medroxyprogesterone | Rattus norvegicus (Norway rat) | IC50 | 0.0190 | 1 | 0 |
| medroxyprogesterone | Rattus norvegicus (Norway rat) | Ki | 0.0086 | 1 | 0 |
| 1-naphthylisothiocyanate | Rattus norvegicus (Norway rat) | IC50 | 15.4030 | 1 | 0 |
| 1-naphthylisothiocyanate | Rattus norvegicus (Norway rat) | Ki | 7.0010 | 1 | 0 |
| megestrol acetate | Rattus norvegicus (Norway rat) | IC50 | 0.0190 | 1 | 0 |
| megestrol acetate | Rattus norvegicus (Norway rat) | Ki | 0.0088 | 1 | 0 |
| pregnenolone carbonitrile | Rattus norvegicus (Norway rat) | IC50 | 13.9570 | 1 | 0 |
| pregnenolone carbonitrile | Rattus norvegicus (Norway rat) | Ki | 6.3440 | 1 | 0 |
| flurandrenolone | Rattus norvegicus (Norway rat) | IC50 | 0.0044 | 1 | 0 |
| flurandrenolone | Rattus norvegicus (Norway rat) | Ki | 0.0020 | 1 | 0 |
| beclomethasone | Rattus norvegicus (Norway rat) | IC50 | 0.0082 | 1 | 0 |
| beclomethasone | Rattus norvegicus (Norway rat) | Ki | 0.0037 | 1 | 0 |
| danazol | Rattus norvegicus (Norway rat) | IC50 | 4.3140 | 1 | 0 |
| danazol | Rattus norvegicus (Norway rat) | Ki | 1.9610 | 1 | 0 |
| triamcinolone | Rattus norvegicus (Norway rat) | IC50 | 0.0580 | 1 | 0 |
| triamcinolone | Rattus norvegicus (Norway rat) | Ki | 0.0260 | 1 | 0 |
| clobetasol propionate | Rattus norvegicus (Norway rat) | IC50 | 0.0015 | 1 | 0 |
| clobetasol propionate | Rattus norvegicus (Norway rat) | Ki | 0.0007 | 1 | 0 |
| mifepristone | Rattus norvegicus (Norway rat) | IC50 | 0.0022 | 1 | 0 |
| mifepristone | Rattus norvegicus (Norway rat) | Ki | 0.0010 | 1 | 0 |
| diflorasone diacetate | Rattus norvegicus (Norway rat) | IC50 | 0.0064 | 1 | 0 |
| diflorasone diacetate | Rattus norvegicus (Norway rat) | Ki | 0.0029 | 1 | 0 |
| flunisolide | Rattus norvegicus (Norway rat) | IC50 | 0.0053 | 1 | 0 |
| flunisolide | Rattus norvegicus (Norway rat) | Ki | 0.0024 | 1 | 0 |
| estradiol 3-benzoate | Rattus norvegicus (Norway rat) | IC50 | 5.0740 | 1 | 0 |
| estradiol 3-benzoate | Rattus norvegicus (Norway rat) | Ki | 2.3060 | 1 | 0 |
| cortisone | Rattus norvegicus (Norway rat) | IC50 | 2.3780 | 1 | 0 |
| cortisone | Rattus norvegicus (Norway rat) | Ki | 1.0810 | 1 | 0 |
| fludrocortisone acetate | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 0 |
| fludrocortisone acetate | Rattus norvegicus (Norway rat) | Ki | 0.0093 | 1 | 0 |
| picrotin | Rattus norvegicus (Norway rat) | IC50 | 117.3000 | 1 | 1 |
| picrotoxinin | Rattus norvegicus (Norway rat) | IC50 | 2.4000 | 1 | 1 |
| halcinonide | Rattus norvegicus (Norway rat) | IC50 | 0.0016 | 1 | 0 |
| halcinonide | Rattus norvegicus (Norway rat) | Ki | 0.0007 | 1 | 0 |
| diethylstilbestrol | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 0 |
| diethylstilbestrol | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 0 |
| pulmicort | Rattus norvegicus (Norway rat) | IC50 | 0.0045 | 1 | 0 |
| pulmicort | Rattus norvegicus (Norway rat) | Ki | 0.0020 | 1 | 0 |
| ethisterone | Rattus norvegicus (Norway rat) | IC50 | 0.2090 | 1 | 0 |
| ethisterone | Rattus norvegicus (Norway rat) | Ki | 0.0950 | 1 | 0 |
| desoximetasone | Rattus norvegicus (Norway rat) | IC50 | 0.0026 | 1 | 0 |
| desoximetasone | Rattus norvegicus (Norway rat) | Ki | 0.0012 | 1 | 0 |