clotrimazole has been researched along with Sensitivity and Specificity in 14 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Activation of PXR has the potential to initiate adverse effects, causing drug-drug interactions, and perturbing normal physiological functions." | 1.38 | QSAR model for human pregnane X receptor (PXR) binding: screening of environmental chemicals and correlations with genotoxicity, endocrine disruption and teratogenicity. ( Dybdahl, M; Jónsdóttir, SÓ; Niemelä, JR; Nikolov, NG; Wedebye, EB, 2012) |
| "Resazurin has been used in recent years to test drugs against different parasites, including trichomonadid protozoa; however, the reproducibility of these resazurin-based methods in our laboratory has been limited because the flagellate culture medium spontaneously reduces the resazurin." | 1.38 | Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs. ( Barrio, AG; Escribano, AI; García-Trevijano, JA; Marcel, AM; Redó, VJ; Ruiz, JJ; Tugores, YM, 2012) |
| "Clotrimazole (CLT) has recently been shown to be a potent and specific inhibitor of the Ca(2+)-activated K+ channel and to thereby prevent K+ loss and cellular dehydration of sickled erythrocytes." | 1.29 | HPLC measurement, blood distribution, and pharmacokinetics of oral clotrimazole, potentially useful antisickling agent. ( Armsby, CC; Brugnara, C; Law, T; Mikati, M; Platt, O; Rifai, N; Sakamoto, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Feng, BY | 1 |
| Toyama, BH | 1 |
| Wille, H | 1 |
| Colby, DW | 1 |
| Collins, SR | 1 |
| May, BC | 1 |
| Prusiner, SB | 1 |
| Weissman, J | 1 |
| Shoichet, BK | 1 |
| Repo, S | 1 |
| Jyrkkärinne, J | 1 |
| Pulkkinen, JT | 1 |
| Laatikainen, R | 1 |
| Honkakoski, P | 1 |
| Johnson, MS | 1 |
| Shen, L | 1 |
| Liu, SJ | 1 |
| Zhang, NS | 1 |
| Dai, GL | 1 |
| Zou, C | 1 |
| Li, CY | 1 |
| Chen, XH | 1 |
| Ju, WZ | 1 |
| Garcia Ferreira, P | 1 |
| Guimarães de Souza Lima, C | 1 |
| Noronha, LL | 1 |
| de Moraes, MC | 1 |
| Silva, FCD | 1 |
| Lifsitch Viçosa, A | 1 |
| Omena Futuro, D | 1 |
| Francisco Ferreira, V | 1 |
| Dybdahl, M | 1 |
| Nikolov, NG | 1 |
| Wedebye, EB | 1 |
| Jónsdóttir, SÓ | 1 |
| Niemelä, JR | 1 |
| Escribano, AI | 1 |
| Marcel, AM | 1 |
| Tugores, YM | 1 |
| Ruiz, JJ | 1 |
| Redó, VJ | 1 |
| García-Trevijano, JA | 1 |
| Barrio, AG | 1 |
| Takei, S | 1 |
| Iseda, T | 1 |
| Yokoyama, M | 1 |
| Hamoudová, R | 1 |
| Pospísilová, M | 1 |
| Kavalírová, A | 1 |
| Solich, P | 1 |
| Sícha, J | 1 |
| Peschka, M | 1 |
| Roberts, PH | 1 |
| Knepper, TP | 1 |
| Rifai, N | 1 |
| Sakamoto, M | 1 |
| Law, T | 1 |
| Platt, O | 1 |
| Mikati, M | 1 |
| Armsby, CC | 1 |
| Brugnara, C | 1 |
| Zhu, J | 1 |
| Coscolluella, C | 1 |
| Crego, AL | 1 |
| Gómez, J | 1 |
| Marina, ML | 1 |
| Lavandera, JL | 1 |
| Fernández-Torres, B | 1 |
| Pereiro, M | 1 |
| Guarro, J | 1 |
14 other studies available for clotrimazole and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Small-molecule aggregates inhibit amyloid polymerization.
Topics: Acetophenones; Animals; Benzopyrans; beta-Lactamase Inhibitors; beta-Lactamases; Clioquinol; Congo R | 2008 |
Ligand specificity of constitutive androstane receptor as probed by induced-fit docking and mutagenesis.
Topics: Animals; Clotrimazole; Constitutive Androstane Receptor; Crystallography, X-Ray; Ethinyl Estradiol; | 2008 |
Sensitive and selective LC-MS/MS assay for quantitation of flutrimazole in human plasma.
Topics: Antifungal Agents; Biological Assay; Chromatography, Liquid; Clotrimazole; Humans; Reproducibility o | 2017 |
Development of a Method for the Quantification of Clotrimazole and Itraconazole and Study of Their Stability in a New Microemulsion for the Treatment of Sporotrichosis.
Topics: Antifungal Agents; Calorimetry, Differential Scanning; Clotrimazole; Drug Compounding; Drug Interact | 2019 |
QSAR model for human pregnane X receptor (PXR) binding: screening of environmental chemicals and correlations with genotoxicity, endocrine disruption and teratogenicity.
Topics: Clotrimazole; Felodipine; Humans; Ligands; Mutagenicity Tests; Pregnane X Receptor; Quantitative Str | 2012 |
Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs.
Topics: Antitrichomonal Agents; Clotrimazole; Fluorometry; High-Throughput Screening Assays; Metronidazole; | 2012 |
Inhibitory effect of clotrimazole on angiogenesis associated with bladder epithelium proliferation in rats.
Topics: Animals; Base Sequence; Butylhydroxybutylnitrosamine; Cell Division; Clotrimazole; Disease Models, A | 2003 |
Separation and determination of clotrimazole, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography.
Topics: Anti-Infective Agents, Local; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutic | 2006 |
Analysis, fate studies and monitoring of the antifungal agent clotrimazole in the aquatic environment.
Topics: Antifungal Agents; Chromatography, Liquid; Clotrimazole; Environmental Monitoring; Gas Chromatograph | 2007 |
HPLC measurement, blood distribution, and pharmacokinetics of oral clotrimazole, potentially useful antisickling agent.
Topics: Adenosine Triphosphatases; Anemia, Sickle Cell; Biological Transport; Chromatography, High Pressure | 1995 |
Chromatographic assay of pharmaceutical compounds under column overloading.
Topics: Chromatography, High Pressure Liquid; Clotrimazole; Mometasone Furoate; Pregnadienediols; Reproducib | 2000 |
Application of capillary zone electrophoresis with off-line solid-phase extraction to in vitro metabolism studies of antifungals.
Topics: Acetic Acid; Acetonitriles; Antifungal Agents; Clotrimazole; Drug Stability; Electrophoresis, Capill | 2001 |
Comparison of two methods for antifungal susceptibility testing of Trichophyton rubrum.
Topics: Antifungal Agents; Clotrimazole; Culture Media; Humans; Itraconazole; Ketoconazole; Microbial Sensit | 2002 |