Page last updated: 2024-12-07

prolamins

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Prolamins: A group of seed storage proteins restricted to the POACEAE family. They are rich in GLUTAMINE and PROLINE. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
PoaceaefamilyA large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.[MeSH]PoaceaeA large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.[MeSH]

Cross-References

ID SourceID
PubMed CID95924
MeSH IDM0516537

Synonyms (21)

Synonym
nsc-43003
6309-98-4
nsc43003
avenin
carbamic acid, phosphono-, c-isopropyl p,p-dimethyl ester
carbamic acid, phosphono-, c-isopropyl dimethyl ester
nsc 43003
1-methylethyl (dimethoxyphosphinyl)carbamate
ai3-31943
brn 1785625
avenin (pesticide)
carbamic acid, phosphono-, isopropyl dimethyl ester
phosphonocarbamic acid c-isopropyl dimethyl ester
carbamic acid, (dimethoxyphosphinyl)-, 1-methylethyl ester
propan-2-yl n-dimethoxyphosphorylcarbamate
prolamins
DTXSID30212417
Q4055620
isopropyl (dimethoxyphosphoryl)carbamate
STARBLD0001169
AKOS040746597

Research Excerpts

Overview

Prolamins are a group of safe food additives that are biocompatible, biodegradable, and sustainable.

ExcerptReferenceRelevance
"Prolamins are a group of safe food additives that are biocompatible, biodegradable, and sustainable. "( Prolamin-based complexes: Structure design and food-related applications.
Fang, Y; Gul, K; Mata, A; Song, J; Sun, C, 2021
)
2.06

Toxicity

ExcerptReferenceRelevance
" Literature was reviewed to evaluate whether an upper limit for gluten content in food, which would be safe for sufferers from both diseases, could be identified."( Review article: safe amounts of gluten for patients with wheat allergy or coeliac disease.
Crevel, R; Hischenhuber, C; Jarry, B; Mäki, M; Moneret-Vautrin, DA; Romano, A; Troncone, R; Ward, R, 2006
)
0.33
" As a microbial TG is included in many food technological processes, its safe use should be checked."( Transglutaminases: a meeting point for wheat allergy, celiac disease, and food safety.
Malandain, H, 2005
)
0.33
" spelta) were found to exert toxic effects on Caco-2/TC7 cells and to agglutinate K562(S) cells."( Environmental factors of celiac disease: cytotoxicity of hulled wheat species Triticum monococcum, T. turgidum ssp. dicoccum and T. aestivum ssp. spelta.
De Vincenzi, M; Dessi, M; Gazza, L; Maialetti, F; Pogna, NE; Silano, M; Vincentini, O, 2007
)
0.34
"The results have shown a constant and significant toxic effect of spelt wheat which is not shared by the two other ancient cereals."( Environmental factors of celiac disease: cytotoxicity of hulled wheat species Triticum monococcum, T. turgidum ssp. dicoccum and T. aestivum ssp. spelta.
De Vincenzi, M; Dessi, M; Gazza, L; Maialetti, F; Pogna, NE; Silano, M; Vincentini, O, 2007
)
0.34
" These differences may explain the different clinical responses observed in patients suffering from CD and open up a means to identify immunologically safe oat cultivars, which could be used to enrich a gluten-free diet."( Diversity in oat potential immunogenicity: basis for the selection of oat varieties with no toxicity in coeliac disease.
Barro, F; Cebolla, A; Comino, I; Cornell, H; de Lorenzo, L; López-Casado, MÁ; Lorite, P; Real, A; Sousa, C; Torres, MI, 2011
)
0.37
" Technical processing may render gluten-containing foods safe for consumption by celiac patients, but so far in vivo safety testing can only be performed on patients."( Testing safety of germinated rye sourdough in a celiac disease model based on the adoptive transfer of prolamin-primed memory T cells into lymphopenic mice.
Andersson, LC; Freitag, TL; Loponen, J; Meri, S; Messing, M; Saavalainen, P; Salovaara, H; Schuppan, D; Sontag-Strohm, T; Zevallos, V, 2014
)
0.4

Bioavailability

ExcerptReferenceRelevance
" The present study was carried out to elucidate the superiority of AE-RP compared to SD-RP in bioavailability in growing rats."( Superiority of alkali-extracted rice protein in bioavailability to starch degraded rice protein comes from digestion of prolamin in growing rats.
Kadowaki, M; Kubota, M; Kumagai, T; Saito, M; Watanabe, R; Watanabe, T, 2009
)
0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (348)

TimeframeStudies, This Drug (%)All Drugs %
pre-199028 (8.05)18.7374
1990's64 (18.39)18.2507
2000's101 (29.02)29.6817
2010's118 (33.91)24.3611
2020's37 (10.63)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 57.17

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index57.17 (24.57)
Research Supply Index5.91 (2.92)
Research Growth Index4.88 (4.65)
Search Engine Demand Index93.51 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (57.17)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials3 (0.82%)5.53%
Reviews31 (8.52%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other330 (90.66%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]