Page last updated: 2024-10-14

buagafuran

Description

buagafuran: a potential antianxiety drug; structure in first souce [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11300005
SCHEMBL ID3251785
MeSH IDM0523331

Synonyms (6)

Synonym
SCHEMBL3251785
buagafuran
CS-0015596
4-butyl-alpha-agarofuran
HY-19496
(1r,6s,9r)-2-butyl-6,10,10-trimethyl-11-oxatricyclo[7.2.1.01,6]dodec-2-ene

Bioavailability

The poor bioavailability of buagafuran may be partially due to the effect of P-gp on its absorption and transportation in intestinal lumen.

ExcerptReference
" The poor bioavailability of buagafuran may be partially due to the effect of P-gp on its absorption and transportation in intestinal lumen."( [Effect of P-glycoprotein on the absorption of buagafuran in rat intestinal lumen].
Li, E; Li, Y, 2008
)
" The results suggested that the poor bioavailability of buagafuran was mostly due to the interplay of P-gp and CYP3A on the absorption, transport and metabolism of buagafuran in intestine of rats."( [Effect of CYP3A and P-glycoprotein on the absorption of buagafuran in rat intestinal lumen].
Chen, H; Hu, JP; Li, Y; Sheng, L; Tan, W, 2010
)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]