| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| serine | [no description available] | medium | 1 | 0 | L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| aniline | [no description available] | medium | 1 | 0 | anilines;
primary arylamine | |
| ferric ferrocyanide | [no description available] | medium | 1 | 0 | | |
| deferrioxamine e | [no description available] | medium | 1 | 0 | cyclic desferrioxamine;
cyclic hydroxamic acid;
macrocycle | antineoplastic agent;
bacterial metabolite;
marine metabolite;
siderophore |
| monactin | [no description available] | medium | 10 | 0 | | |
| dinactin | [no description available] | medium | 9 | 0 | | |
| trinactin | [no description available] | medium | 10 | 0 | | |
| chlorine | [no description available] | medium | 2 | 0 | halide anion;
monoatomic chlorine | cofactor;
Escherichia coli metabolite;
human metabolite |
| triazoles | [no description available] | medium | 2 | 0 | 1,2,3-triazole | |
| isovaleric acid | [no description available] | medium | 1 | 0 | branched-chain saturated fatty acid;
methylbutyric acid;
short-chain fatty acid | mammalian metabolite;
plant metabolite |
| isobutyric acid | [no description available] | medium | 2 | 0 | branched-chain saturated fatty acid;
fatty acid 4:0;
methyl-branched fatty acid | Daphnia magna metabolite;
plant metabolite;
volatile oil component |
| vancomycin | [no description available] | medium | 1 | 0 | glycopeptide | antibacterial drug;
antimicrobial agent;
bacterial metabolite |
| levulinic acid | [no description available] | medium | 1 | 0 | oxopentanoic acid;
straight-chain saturated fatty acid | plant metabolite |
| ammonium hydroxide | [no description available] | medium | 2 | 0 | azane;
gas molecular entity;
mononuclear parent hydride | EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant |
| merocyanine dye | [no description available] | medium | 1 | 0 | | |
| squalestatin 1 | [no description available] | medium | 1 | 0 | acetate ester;
cyclic ketal;
oxabicycloalkane;
polyketide;
tertiary alcohol;
tricarboxylic acid | EC 2.5.1.21 (squalene synthase) inhibitor;
fungal metabolite |
| moxidectin | [no description available] | medium | 1 | 0 | | |
| urea | [no description available] | medium | 3 | 0 | isourea;
monocarboxylic acid amide;
one-carbon compound | Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| nile blue | [no description available] | medium | 1 | 0 | | |
| eth 1001 | [no description available] | medium | 1 | 0 | | |
| thallium | [no description available] | medium | 4 | 0 | boron group element atom | |
| palmitic acid | [no description available] | medium | 1 | 0 | long-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite |
| valinomycin | [no description available] | medium | 22 | 0 | cyclodepsipeptide;
macrocycle | antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore |
| chlorpromazine | [no description available] | medium | 1 | 0 | organochlorine compound;
phenothiazines;
tertiary amine | anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug |
| benzyl alcohol | [no description available] | medium | 1 | 0 | benzyl alcohols | antioxidant;
fragrance;
metabolite;
solvent |
| glycolipids | [no description available] | medium | 1 | 0 | | |
| tetraphenylborate | [no description available] | medium | 2 | 0 | | |
| titanium | [no description available] | medium | 1 | 0 | titanium group element atom | |
| tetranactin | [no description available] | medium | 4 | 0 | macrotetrolide | |
| nigericin | [no description available] | medium | 6 | 0 | polycyclic ether | antibacterial agent;
antimicrobial agent;
bacterial metabolite;
potassium ionophore |
| monensin | [no description available] | medium | 6 | 0 | cyclic hemiketal;
monocarboxylic acid;
polyether antibiotic;
spiroketal | antifungal agent;
coccidiostat;
ionophore |
| antimycin a | [no description available] | medium | 1 | 0 | amidobenzoic acid | |
| carbonyl cyanide p-trifluoromethoxyphenylhydrazone | [no description available] | medium | 4 | 0 | aromatic ether;
hydrazone;
nitrile;
organofluorine compound | ATP synthase inhibitor;
geroprotector;
ionophore |
| carbon monoxide | [no description available] | medium | 1 | 0 | carbon oxide;
gas molecular entity;
one-carbon compound | biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent |
| bepridil | [no description available] | medium | 1 | 0 | pyrrolidines;
tertiary amine | anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent |
| 3-phenylindole | [no description available] | medium | 1 | 0 | | |
| calcimycin | [no description available] | medium | 4 | 0 | benzoxazole | |
| chloramphenicol | [no description available] | medium | 1 | 0 | C-nitro compound;
carboxamide;
diol;
organochlorine compound | antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor |
| hydrogen | [no description available] | medium | 1 | 0 | elemental hydrogen;
elemental molecule;
gas molecular entity | antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite |
| cesium | [no description available] | medium | 2 | 0 | alkali metal atom | |
| rubidium | [no description available] | medium | 2 | 0 | alkali metal atom | |
| rotenone | [no description available] | medium | 1 | 0 | organic heteropentacyclic compound;
rotenones | antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin |
| triphenylmethylphosphonium | [no description available] | medium | 1 | 0 | | |
| 1-monooleoyl-rac-glycerol | [no description available] | medium | 2 | 0 | 1-acylglycerol 18:1;
monooleoylglycerol | plant metabolite |
| triolein | [no description available] | medium | 1 | 0 | triglyceride | Caenorhabditis elegans metabolite;
plant metabolite |
| squalene | [no description available] | medium | 1 | 0 | triterpene | human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| tellurium | [no description available] | medium | 1 | 0 | chalcogen;
metalloid atom | |
| gramicidin a | [no description available] | medium | 4 | 0 | | |
| pirarubicin | [no description available] | medium | 1 | 0 | anthracycline | |
| cyclosporine | [no description available] | medium | 2 | 0 | | |
| methylprednisolone | [no description available] | medium | 1 | 0 | 6-methylprednisolone;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | adrenergic agent;
anti-inflammatory drug;
antiemetic;
environmental contaminant;
neuroprotective agent;
xenobiotic |
| cycloheximide | [no description available] | medium | 1 | 0 | antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol | anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor |
| okadaic acid | [no description available] | medium | 1 | 0 | ketal | |
| calmidazolium | [no description available] | medium | 1 | 0 | imidazolium ion | apoptosis inducer;
calmodulin antagonist |
| 4-aminopyridine | [no description available] | medium | 1 | 0 | aminopyridine;
aromatic amine | avicide;
orphan drug;
potassium channel blocker |
| cyclic cmp | [no description available] | medium | 1 | 0 | 3',5'-cyclic pyrimidine nucleotide | human metabolite |
| cyclic gmp | [no description available] | medium | 1 | 0 | 3',5'-cyclic purine nucleotide;
guanyl ribonucleotide | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| ouabain | [no description available] | medium | 1 | 0 | 11alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone | anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite |
| gallic acid | [no description available] | medium | 1 | 0 | trihydroxybenzoic acid | antineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite |
| verapamil | [no description available] | medium | 1 | 0 | aromatic ether;
nitrile;
polyether;
tertiary amino compound | |
| 1-methyl-3-isobutylxanthine | [no description available] | medium | 1 | 0 | 3-isobutyl-1-methylxanthine | |
| 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate | [no description available] | medium | 1 | 0 | trihydroxybenzoic acid | |
| 4-chloro-7-nitrobenzofurazan | [no description available] | medium | 1 | 0 | benzoxadiazole;
C-nitro compound;
organochlorine compound | EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor;
fluorescent probe;
fluorochrome |
| potassium chloride | [no description available] | medium | 1 | 0 | inorganic chloride;
inorganic potassium salt;
potassium salt | fertilizer |
| carbonyl cyanide m-chlorophenyl hydrazone | [no description available] | medium | 2 | 0 | hydrazone;
monochlorobenzenes;
nitrile | antibacterial agent;
geroprotector;
ionophore |
| phosphatidylcholines | [no description available] | medium | 5 | 0 | 1,2-diacyl-sn-glycero-3-phosphocholine | |
| enniatin b | [no description available] | medium | 1 | 0 | enniatin | antimicrobial agent |
| alamethicin | [no description available] | medium | 2 | 0 | | |
| tacrolimus | [no description available] | medium | 1 | 0 | macrolide lactam | bacterial metabolite;
immunosuppressive agent |
| lithium | [no description available] | medium | 1 | 0 | alkali metal atom | |
| sb 203580 | [no description available] | medium | 1 | 0 | imidazoles;
monofluorobenzenes;
pyridines;
sulfoxide | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent |
| mizoribine | [no description available] | medium | 1 | 0 | imidazoles | anticoronaviral agent |
| succinic acid | [no description available] | medium | 1 | 0 | alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid | anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent |
| malonic acid | [no description available] | medium | 1 | 0 | alpha,omega-dicarboxylic acid | human metabolite |
| 2,4-dichlorophenoxyacetic acid | [no description available] | medium | 2 | 0 | chlorophenoxyacetic acid;
dichlorobenzene | agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin |
| melitten | [no description available] | medium | 1 | 0 | | |
| 1,2-dipalmitoylphosphatidylcholine | [no description available] | medium | 2 | 0 | | |
| lasalocid | [no description available] | medium | 2 | 0 | beta-hydroxy ketone;
monocarboxylic acid;
monohydroxybenzoic acid;
oxanes;
oxolanes;
polyether antibiotic;
secondary alcohol;
tertiary alcohol | bacterial metabolite;
coccidiostat;
ionophore |
| 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid | [no description available] | medium | 3 | 0 | | |
| 4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid | [no description available] | medium | 3 | 0 | stilbenoid | |
| lysine | [no description available] | medium | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid | algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| alanine | [no description available] | medium | 1 | 0 | alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid | EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite |
| leucine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| glutamic acid | [no description available] | medium | 1 | 0 | glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical |
| parinaric acid | [no description available] | medium | 1 | 0 | octadecatetraenoic acid | |
| 1,2-oleoylphosphatidylcholine | [no description available] | medium | 1 | 0 | phosphatidylcholine(1+) | |
| lucifer yellow | [no description available] | medium | 1 | 0 | organic lithium salt | fluorochrome |
| sq-23377 | [no description available] | medium | 1 | 0 | cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid | calcium ionophore;
metabolite |
| beauvericin | [no description available] | medium | 1 | 0 | | |
| lanthanum | [no description available] | medium | 1 | 0 | f-block element atom;
lanthanoid atom;
scandium group element atom | |
| sanguinarine | [no description available] | medium | 1 | 0 | alkaloid antibiotic;
benzophenanthridine alkaloid;
botanical anti-fungal agent | |
| tyrosine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine | EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical |
| phloretin | [no description available] | medium | 2 | 0 | dihydrochalcones | antineoplastic agent;
plant metabolite |
| furosemide | [no description available] | medium | 1 | 0 | chlorobenzoic acid;
furans;
sulfonamide | environmental contaminant;
loop diuretic;
xenobiotic |
| tryptophan | [no description available] | medium | 1 | 0 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan | antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| dimyristoylphosphatidylcholine | [no description available] | medium | 1 | 0 | 1,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester | antigen;
mouse metabolite |
| 1,2-diphytanoylphosphatidylcholine | [no description available] | medium | 1 | 0 | | |
| phenyl acetate | [no description available] | medium | 1 | 0 | benzenes;
phenyl acetates | |