Proteins > Neuronal acetylcholine receptor subunit beta-2
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Neuronal acetylcholine receptor subunit beta-2
A neuronal acetylcholine receptor subunit beta-2 that is encoded in the genome of mouse. [OMA:Q9ERK7, PRO:DNx]
Synonyms
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (7)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| nicotine | Mus musculus (house mouse) | EC50 | 0.7222 | 1 | 2 |
Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations.European journal of medicinal chemistry, , Sep-18, Volume: 102, 2015
Structure-activity studies of 7-heteroaryl-3-azabicyclo[3.3.1]non-6-enes: a novel class of highly potent nicotinic receptor ligands.Journal of medicinal chemistry, , Nov-26, Volume: 55, Issue:22, 2012
(-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine.Bioorganic & medicinal chemistry letters, , Oct-21, Volume: 12, Issue:20, 2002
(S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors.Journal of medicinal chemistry, , Aug-16, Volume: 39, Issue:17, 1996
Dual Nicotinic Acetylcholine Receptor α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts.Journal of medicinal chemistry, , 02-22, Volume: 61, Issue:4, 2018
Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists.Journal of medicinal chemistry, , Dec-12, Volume: 56, Issue:23, 2013