A dual specificity calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C that is encoded in the genome of rat. [OMA:Q63421, PRO:DNx]
Cam-PDE 1C;
3',5'-cyclic-AMP phosphodiesterase;
3.1.4.-;
3',5'-cyclic-GMP phosphodiesterase;
3.1.4.35
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| caffeine | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| 1-methyl-3-isobutylxanthine | Rattus norvegicus (Norway rat) | IC50 | 0.1000 | 1 | 1 |
| 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| rolipram | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| 3,5,7,3',4'-pentamethoxyflavone | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| penta-o-ethylquercetin | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| quercetin | Rattus norvegicus (Norway rat) | IC50 | 275.0000 | 1 | 1 |
| sildenafil | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 1 |
| zaprinast | Rattus norvegicus (Norway rat) | IC50 | 93.3000 | 1 | 1 |