Compounds > dipsacoside b

Page last updated: 2024-11-13

dipsacoside b

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

dipsacoside B: from flowers of Lonicera macranthoides Hand [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Flora	Rank	Flora Definition	Family	Family Definition
Lonicera	genus	A plant genus of the family CAPRIFOLIACEAE. Members contain iridoid glucosides.[MeSH]	Caprifoliaceae	A plant family of the order Dipsacales, subclass Asteridae, class Magnoliopsida.[MeSH]

Cross-References

ID Source	ID
PubMed CID	21627940
MeSH ID	M0222073

Synonyms (19)

Synonym
olean-12-en-28-oic acid, 3-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-alpha-l-arabinopyranosyl)oxy)-23-hydroxy-, 6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl ester, (3beta,4alpha)-
unii-e5h3t7090c
33289-85-9
e5h3t7090c ,
dipsacoside b
S9016
AC-34056
glycoside l-g3
olean-12-en-28-oic acid, 3-((2-o-(6-deoxy-.alpha.-l-mannopyranosyl)-.alpha.-l-arabinopyranosyl)oxy)-23-hydroxy-, 6-o-.beta.-d-glucopyranosyl-.beta.-d-glucopyranosyl ester, (3.beta.,4.alpha.)-
hederagenin 3-o-.alpha.-l-rhamnopyranosyl(1->2)-.alpha.-l-arabinopyranosyl-28-o-.beta.-d-glucopyranosyl(1->6)-.beta.-d-glucopyranoside
dipsacus saponin m
tauroside g3
CS-6025
HY-N0266
mfcd03424249
AKOS037514628
CCG-270629
Q27276893
AS-56459

Research Excerpts

Pharmacokinetics

Excerpt	Reference	Relevance
" This developed method was subsequently successfully applied to pharmacokinetic profiles of the four saponins in rats."	( Liquid chromatography-mass spectrometry analysis of macranthoidin B, macranthoidin A, dipsacoside B, and macranthoside B in rat plasma for the pharmacokinetic investigation. Chen, CY; Li, P; Qi, LW; Wen, XD; Yi, L, 2009)	0.58

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	1 (11.11)	18.2507
2000's	1 (11.11)	29.6817
2010's	5 (55.56)	24.3611
2020's	2 (22.22)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.67 (24.57)
Research Supply Index	2.30 (2.92)
Research Growth Index	4.97 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.67)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
quinic acid (-)-quinic acid : The (-)-enantiomer of quinic acid.	2.06	1	0
oleanolic acid [no description available]	3.57	8	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
glucose, (beta-d)-isomer beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.	2.11	1	0	D-glucopyranose	epitope; mouse metabolite
pulsatilla saponin a Pulsatilla saponin A: has antineoplastic activity; isolated from Pulsatilla chinensis; structure in first source. kalopanaxsaponin A : A triterpenoid saponin that is hederagenin attached to a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage. It has been isolated from the stem bark of Kalopanax pictus.	2.21	1	0	disaccharide derivative; hydroxy monocarboxylic acid; pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; plant metabolite
angiotensin ii Giapreza: injectable form of angiotensin II used to increase blood pressure in adult patients with septic or other distributive shock. Ile(5)-angiotensin II : An angiotensin II that acts on the central nervous system (PDB entry: 1N9V).	2.41	1	0	amino acid zwitterion; angiotensin II	human metabolite
beta-hederin beta-hederin: derived from beta-amyrin; other hederigenin based saponins are available	2.21	1	0	triterpenoid
caffeic acid trans-caffeic acid : The trans-isomer of caffeic acid.	2.11	1	0	caffeic acid	geroprotector; mouse metabolite
chlorogenic acid caffeoylquinic acid: Antiviral Agent; structure in first source. chlorogenate : A monocarboxylic acid anion that is the conjugate base of chlorogenic acid; major species at pH 7.3.	2.78	3	0	cinnamate ester; tannin	food component; plant metabolite
luteolin [no description available]	2.11	1	0	3'-hydroxyflavonoid; tetrahydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; c-Jun N-terminal kinase inhibitor; EC 2.3.1.85 (fatty acid synthase) inhibitor; immunomodulator; nephroprotective agent; plant metabolite; radical scavenger; vascular endothelial growth factor receptor antagonist
luteolin-7-glucoside luteolin-7-glucoside: has both antiasthmatic and antineoplastic activities; has 3C protease inhibitory activity; isolated from Ligustrum lucidum. luteolin 7-O-beta-D-glucoside : A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.	2.11	1	0	beta-D-glucoside; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	antioxidant; plant metabolite
rutin Hydroxyethylrutoside: Monohydroxyethyl derivative of rutin. Peripheral circulation stimulant used in treatment of venous disorders.	2.06	1	0	disaccharide derivative; quercetin O-glucoside; rutinoside; tetrahydroxyflavone	antioxidant; metabolite
isochlorogenic acid [no description available]	2.11	1	0	quinic acid
beta-escin [no description available]	3.57	8	0
4,5-dicaffeoyl quinic acid 4,5-dicaffeoyl quinic acid: structure in first source	2.06	1	0
macranthoidin b [no description available]	8.31	6	0

Condition	Indicated	Relationship Strength	Studies	Trials
Acute Ischemic Stroke [description not available]	0	2.41	1	0
Anoxemia [description not available]	0	2.41	1	0
Acute Brain Injuries [description not available]	0	2.41	1	0
Ischemic Stroke Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.	0	7.41	1	0
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms.	0	2.41	1	0
Brain Injuries Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.	0	2.41	1	0
Neointima The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.	0	3.33	4	0
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	0	2.05	1	0