| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
coumarin
2H-chromen-2-one: coumarin derivative | 2.06 | 1 | 0 | coumarins | fluorescent dye;
human metabolite;
plant metabolite |
1,10-phenanthroline
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases | 2.01 | 1 | 0 | phenanthroline | EC 2.7.1.1 (hexokinase) inhibitor;
EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor |
minoxidil
Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371). minoxidil : A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6. | 2.08 | 1 | 0 | dialkylarylamine;
tertiary amino compound | |
spiperone
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.. spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively. | 2.08 | 1 | 0 | aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound | alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist |
pilocarpine hydrochloride
pilocarpine hydrochloride : The hydrochloride salt of (+)-pilocarpine, a medication used to treat increased pressure inside the eye and dry mouth. | 2.08 | 1 | 0 | hydrochloride | |
edetic acid
Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. | 2.01 | 1 | 0 | ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid | anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector |
leucine
Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group. | 2.01 | 1 | 0 | amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
methionine
Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. | 2.02 | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid | antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
arginine
Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. | 2.07 | 1 | 0 | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
triethylamine
[no description available] | 2 | 1 | 0 | tertiary amine | |
thiazoles
[no description available] | 2.07 | 1 | 0 | 1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
hydrazine
diamine : Any polyamine that contains two amino groups. | 2.1 | 1 | 0 | azane;
hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor |
diazomethane
Diazomethane: A diazonium compound with the formula CH2N2.. diazomethane : The simplest diazo compound, in which a diazo group is attached to a methylene group. | 1.97 | 1 | 0 | diazo compound | alkylating agent;
antineoplastic agent;
carcinogenic agent;
poison |
rhein
[no description available] | 2.08 | 1 | 0 | dihydroxyanthraquinone | |
herniarin
herniarin: methoxy analog of umbelliferone; structure. herniarin : A member of the class of coumarins that is coumarin substituted by a methoxy group at position 7. | 2.06 | 1 | 0 | coumarins | fluorochrome |
bethanechol chloride
bethanechol chloride : The chloride salt of bethanechol. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention. | 2.08 | 1 | 0 | carbamate ester;
chloride salt;
quaternary ammonium salt | muscarinic agonist |
3-hydroxy-1-benzopyran-2-one
3-hydroxycoumarin: Photoprotective from sea urchin gametes and embryonic cells; structure in first source. hydroxycoumarin : Any coumarin carrying at least one hydroxy substituent. | 2.06 | 1 | 0 | hydroxycoumarin | |
thioflavin t
thioflavin T: RN given refers to chloride; structure. thioflavine T : An organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. | 2.07 | 1 | 0 | organic chloride salt | fluorochrome;
geroprotector;
histological dye |
7-methylcoumarin
7-methylcoumarin: structure in first source | 2.06 | 1 | 0 | coumarins | |
fluorine
Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries. | 2.1 | 1 | 0 | diatomic fluorine;
gas molecular entity | NMR chemical shift reference compound |
n-(cyclohexylthio)phthalimide
N-(cyclohexylthio)phthalimide: water pollutant | 2.08 | 1 | 0 | | |
oxcarbazepine
Oxcarbazepine: A carbamazepine derivative that acts as a voltage-gated sodium channel blocker. It is used for the treatment of PARTIAL SEIZURES with or without secondary generalization. It is also an inducer of CYTOCHROME P-450 CYP3A4.. oxcarbazepine : A dibenzoazepine derivative, having a carbamoyl group at the ring nitrogen, substituted with an oxo group at C-4 of the azepeine ring which is also hydrogenated at C-4 and C-5. It is a anticholinergic anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. | 2.08 | 1 | 0 | cyclic ketone;
dibenzoazepine | anticonvulsant;
drug allergen |
etoposide
[no description available] | 2.01 | 1 | 0 | beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound | antineoplastic agent;
DNA synthesis inhibitor |
1,7-phenanthroline
[no description available] | 2.01 | 1 | 0 | phenanthroline | |
ubenimex
ubenimex: growth inhibitor | 2.01 | 1 | 0 | | |
coumarin 153
coumarin 153: structure in first source | 2.03 | 1 | 0 | 7-aminocoumarins | fluorochrome |
ergocornine
ergocornine: a component of ergotoxine; minor descriptor (75-86); on-line & INDEX MEDICUS search ERGOLINES (75-86); RN given refers to ((5'alpha)-isomer). ergocornine : Ergotaman bearing a hydroxy group at the 12' position, isopropyl groups at the 2' and 5'alpha positions, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid. | 2.08 | 1 | 0 | ergot alkaloid | |
butyrylcholine chloride
[no description available] | 2.08 | 1 | 0 | | |
alanylproline
alanylproline: RN given refers to all (L)-isomer | 1.98 | 1 | 0 | dipeptide zwitterion;
dipeptide | metabolite |
monopentyl phthalate
monopentyl phthalate : A phthalic acid monoester obtained by formal condensation of one of the carboxy groups of phthalic acid with the hydroxy group of pentanol. | 2.08 | 1 | 0 | phthalic acid monoester | anti-estrogen;
rat metabolite;
xenobiotic metabolite |
7-amino-4-methylcoumarin
7-amino-4-methylcoumarin: RN given refers to parent cpd | 2.06 | 1 | 0 | 7-aminocoumarins | fluorochrome |
diprotin a
[no description available] | 2.05 | 1 | 0 | peptide | |
peroxyoxalate
[no description available] | 2.71 | 3 | 0 | | |
alpha-(n6-adenyl)styrene oxide
alpha-(N6-adenyl)styrene oxide: structure given in first source; RN given refers to compound with no isomeric designation | 2.08 | 1 | 0 | | |
4-methylumbelliferylguanidinobenzoate
[no description available] | 1.97 | 1 | 0 | | |
arginylarginine
Arg-Arg : A dipeptide formed from two L-arginine residues. | 2.07 | 1 | 0 | dipeptide | Mycoplasma genitalium metabolite |
3-(4-aminophenyl)-2h-chromen-2-one
3-(4-aminophenyl)-2H-chromen-2-one: fluorescent dye for imaging myelin; structure in first source | 2.06 | 1 | 0 | | |
2-[[2-[[4-(2-furanylmethyl)-5-(phenylmethyl)-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
[no description available] | 2.08 | 1 | 0 | aromatic amide;
thiophenes | |
1-(1,3-benzodioxol-5-ylmethyl)-3-hydroxy-3-[2-(4-methylphenyl)-2-oxoethyl]-2-indolone
[no description available] | 2.08 | 1 | 0 | aromatic ketone | |
6-ethyl-N-[2-(4-methoxyphenyl)ethyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
[no description available] | 2.08 | 1 | 0 | triazolopyrimidines | |
7-[2-hydroxy-3-(2-methylphenoxy)propyl]-3-methyl-8-(propan-2-ylthio)purine-2,6-dione
[no description available] | 2.08 | 1 | 0 | oxopurine | |
2-[[5-(1-benzotriazolylmethyl)-1,3,4-oxadiazol-2-yl]thio]-N-[(4-fluorophenyl)methyl]-N-phenylacetamide
[no description available] | 2.08 | 1 | 0 | benzotriazoles | |
3-[(1-cyclopentyl-5-tetrazolyl)-[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-7-methyl-1H-quinolin-2-one
[no description available] | 2.08 | 1 | 0 | piperazines | |
3-[[2-[[5-[(4-cyanophenoxy)methyl]-4-phenyl-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]benzoic acid methyl ester
[no description available] | 2.08 | 1 | 0 | amidobenzoic acid | |
[5-(2-furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone
[no description available] | 2.08 | 1 | 0 | piperazines;
pyridines | |
N-[2-[(3-cyano-6-ethoxy-2-quinolinyl)amino]ethyl]propanamide
[no description available] | 2.08 | 1 | 0 | aminoquinoline | |
4-[3-(1,3-dioxo-2-isoindolyl)propylamino]-2-methylisoindole-1,3-dione
[no description available] | 2.08 | 1 | 0 | phthalimides | |
9-[3-(4-acetyl-3,5-dimethyl-1-pyrazolyl)-2-hydroxypropyl]-6-methyl-3,4-dihydro-2H-carbazol-1-one
[no description available] | 2.08 | 1 | 0 | carbazoles | |
1-phenyl-4-[[1-(phenylmethyl)-5-tetrazolyl]-(3-pyridinyl)methyl]piperazine
[no description available] | 2.08 | 1 | 0 | piperazines | |
1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-phenylurea
[no description available] | 2.08 | 1 | 0 | quinolines | |
N-(2-furanylmethyl)-2-[(4-methoxyphenyl)sulfonylamino]benzamide
[no description available] | 2.08 | 1 | 0 | sulfonamide | |
N-methyl-N-[5-(5-methyl-2-pyrazinyl)-1,3,4-thiadiazol-2-yl]-2-oxolanecarboxamide
[no description available] | 2.08 | 1 | 0 | pyrazines | |
2-[[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]thio]-3-ethyl-4-quinazolinone
[no description available] | 2.08 | 1 | 0 | quinazolines | |
2-[[5-(4-methylphenyl)-3-thiazolo[2,3-c][1,2,4]triazolyl]thio]-N-(6-methyl-2-pyridinyl)acetamide
[no description available] | 2.08 | 1 | 0 | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
4-amino-N5-[2-(2-methoxyethylamino)-1-(5-methyl-2-furanyl)-2-oxoethyl]-N5-(thiophen-2-ylmethyl)isothiazole-3,5-dicarboxamide
[no description available] | 2.08 | 1 | 0 | organonitrogen compound;
organooxygen compound | |
pilocarpine nitrate
[no description available] | 2.08 | 1 | 0 | | |
7-diethylaminocoumarin-3-carboxylic acid
[no description available] | 2.08 | 1 | 0 | | |
5-(4-methoxyphenyl)-7-(4-methylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine
[no description available] | 2.08 | 1 | 0 | methoxybenzenes | |
cyclopropanecarboxylic acid [5-(6-amino-5-cyano-3-methyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)-2-ethoxyphenyl] ester
[no description available] | 2.08 | 1 | 0 | pyranopyrazole | |
2-cyano-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetic acid cyclohexyl ester
[no description available] | 2.08 | 1 | 0 | quinoxaline derivative | |
2-(3-methylphenyl)sulfonyl-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetonitrile
[no description available] | 2.08 | 1 | 0 | quinoxaline derivative | |
5-(3-methoxyphenyl)-N-(2-oxolanylmethyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide
[no description available] | 2.08 | 1 | 0 | pyrimidines | |
2-(4-bromophenyl)-4-methyl-1H-pyrazol-5-one
[no description available] | 2.08 | 1 | 0 | pyrazoles;
ring assembly | |
2-[(4-fluoro-3-methylphenyl)sulfonylamino]acetic acid
[no description available] | 2.08 | 1 | 0 | sulfonamide | |
4-(1H-benzimidazol-2-yl)quinoline
[no description available] | 2.08 | 1 | 0 | quinolines | |
2-[[2-(5,6-dimethyl-1-benzimidazolyl)-1-oxoethyl]amino]benzoic acid methyl ester
[no description available] | 2.08 | 1 | 0 | amidobenzoic acid | |
1-(4-ethylphenyl)-N-(3-pyridinylmethyl)methanamine
[no description available] | 2.08 | 1 | 0 | aromatic amine | |
1-(4-ethoxyphenyl)-3-(6-quinoxalinyl)urea
[no description available] | 2.08 | 1 | 0 | quinoxaline derivative | |
3-methyl-5-propyl-7-furo[3,2-g][1]benzopyranone
[no description available] | 2.08 | 1 | 0 | psoralens | |
4-(1,3-benzothiazol-2-yl)-N-phenyl-1-piperazinecarboxamide
[no description available] | 2.08 | 1 | 0 | N-arylpiperazine | |
2-[4-(pyridin-4-ylmethylsulfamoyl)phenoxy]acetic acid methyl ester
[no description available] | 2.08 | 1 | 0 | monocarboxylic acid | |
5-bromo-N-(pyridin-4-ylmethyl)-2-thiophenesulfonamide
[no description available] | 2.08 | 1 | 0 | thiophenes | |
LSM-16463
[no description available] | 2.08 | 1 | 0 | pyrazoles;
ring assembly | |
4-[2-(9-methyl-6-indolo[3,2-b]quinoxalinyl)ethyl]morpholine
[no description available] | 2.08 | 1 | 0 | quinoxaline derivative | |
4-[[[3-(4-morpholinylsulfonyl)phenyl]-oxomethyl]amino]benzoic acid ethyl ester
[no description available] | 2.08 | 1 | 0 | benzamides | |
5-(2,3-dihydroindol-1-ylsulfonyl)-1,3-diethyl-2-benzimidazolone
[no description available] | 2.08 | 1 | 0 | benzimidazoles | |
N-[2-(4-acetyl-1-piperazinyl)phenyl]-2-(5-methyl-2-propan-2-ylphenoxy)acetamide
[no description available] | 2.08 | 1 | 0 | piperazines | |
N-(2-furanylmethyl)-2-imino-5-oxo-1-(2-phenylethyl)-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamide
[no description available] | 2.08 | 1 | 0 | pyridopyrimidine | |
N-[2-[4-[(4-chlorophenyl)-oxomethyl]-1-piperazinyl]phenyl]-1,3-benzodioxole-5-carboxamide
[no description available] | 2.08 | 1 | 0 | aromatic amide | |
[2-(4-methoxyphenyl)-6-methyl-4-quinolinyl]-(4-morpholinyl)methanone
[no description available] | 2.08 | 1 | 0 | quinolines | |
2-(2-furanyl)-5-methyl-6-(phenylmethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
[no description available] | 2.08 | 1 | 0 | triazolopyrimidines | |
1-[4-[(2-amino-5-thiazolyl)methyl]phenyl]ethanone
[no description available] | 2.08 | 1 | 0 | aromatic ketone | |
N-[2-[4-[(4-chlorophenyl)-oxomethyl]-1-piperazinyl]phenyl]-2-benzofurancarboxamide
[no description available] | 2.08 | 1 | 0 | aromatic amide;
furans | |
2-(3,5-dimethylphenoxy)-N-[3-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]phenyl]acetamide
[no description available] | 2.08 | 1 | 0 | anilide | |
5-(2-furanyl)-N-[1-[(2-methylphenyl)methyl]-3-pyrazolyl]-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide
[no description available] | 2.08 | 1 | 0 | pyrazolopyrimidine | |
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(5,7-diphenyl-2-pyrazolo[1,5-a]pyrimidinyl)methanone
[no description available] | 2.08 | 1 | 0 | pyrimidines | |
4-amino-2-[[4-(1-azepanylsulfonyl)phenyl]-oxomethyl]isoindole-1,3-dione
[no description available] | 2.08 | 1 | 0 | phthalimides | |
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-2-[(6-methyl-1H-benzimidazol-2-yl)thio]acetamide
[no description available] | 2.08 | 1 | 0 | pyrazoles;
ring assembly | |
2-(1-benzimidazolyl)acetic acid [2-[1-(4-methoxyphenyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester
[no description available] | 2.08 | 1 | 0 | alpha-amino acid ester | |
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-phenylacetamide
[no description available] | 2.08 | 1 | 0 | amino acid amide | |
6-amino-5-cyano-4-(2,4-dimethoxyphenyl)-2-(2-ethoxy-2-oxoethyl)-4H-pyran-3-carboxylic acid ethyl ester
[no description available] | 2.08 | 1 | 0 | dimethoxybenzene | |
2-chloro-5-[[2,3-dihydro-1,4-benzodioxin-3-yl(oxo)methyl]amino]benzoic acid methyl ester
[no description available] | 2.08 | 1 | 0 | amidobenzoic acid | |
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-methoxy-4-propan-2-yloxybenzamide
[no description available] | 2.08 | 1 | 0 | benzodioxine | |
3-(3,4-dihydro-2H-quinolin-1-ylmethyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine
[no description available] | 2.08 | 1 | 0 | quinolines | |
benzoic acid [5-(6-benzamido-9-purinyl)-3-fluoro-4-hydroxy-2-oxolanyl]methyl ester
[no description available] | 2.08 | 1 | 0 | 3'-deoxyribonucleoside;
purines | |
2-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)benzoic acid thiophen-2-ylmethyl ester
[no description available] | 2.08 | 1 | 0 | benzoate ester | |
2-benzoyl-N-(6-methoxy-3-pyridinyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide
[no description available] | 2.08 | 1 | 0 | isoquinolines | |
3,5-dimethyl-1-phenyl-4-pyrazolecarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] ester
[no description available] | 2.08 | 1 | 0 | pyrazoles;
ring assembly | |
glycylproline
Gly-Pro : A dipeptide consisting of L-proline having a glycyl residue attached to its alpha-amino group. | 1.98 | 1 | 0 | dipeptide zwitterion;
dipeptide | metabolite |
9-chloro-6-methylindolo[3,2-b]quinoxaline
[no description available] | 2.08 | 1 | 0 | quinoxaline derivative | |
3-chloro-N-[2-[4-(4-fluorophenyl)-1-piperazinyl]-2-(3-pyridinyl)ethyl]benzamide
[no description available] | 2.08 | 1 | 0 | piperazines | |
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide
[no description available] | 2.08 | 1 | 0 | oxadiazole;
ring assembly | |
2-cyclopentyl-4-[1,4-dioxa-8-azaspiro[4.5]decan-8-yl(oxo)methyl]-9-methyl-1-pyrido[3,4-b]indolone
[no description available] | 2.08 | 1 | 0 | beta-carbolines | |
N-(3-chlorophenyl)-5-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-3-methyl-2-benzofurancarboxamide
[no description available] | 2.08 | 1 | 0 | aromatic amide;
furans | |
[4-[6-(4-morpholinyl)-3-pyridazinyl]-1-piperazinyl]-(2-pyridin-4-yl-4-quinolinyl)methanone
[no description available] | 2.08 | 1 | 0 | quinolines | |
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(3-methyl-4-oxo-1-phthalazinyl)acetamide
[no description available] | 2.08 | 1 | 0 | phthalazines | |
5-bromo-N-[2-(6,7-dimethyl-2-oxo-1H-quinolin-3-yl)ethyl]-2-furancarboxamide
[no description available] | 2.08 | 1 | 0 | quinolines | |
3-(2-chlorophenyl)-5-methyl-N-[3-(3-methyl-2-imidazo[1,2-a]pyrimidinyl)phenyl]-4-isoxazolecarboxamide
[no description available] | 2.08 | 1 | 0 | aromatic amide | |
7-(5-chloro-2-methoxyanilino)-6-[(4-methoxyphenyl)methyl]-7H-pyrrolo[3,4-b]pyridin-5-one
[no description available] | 2.08 | 1 | 0 | pyrrolopyridine | |
2-furanyl-[4-(4-tetrazolo[1,5-a]quinoxalinyl)-1-piperazinyl]methanone
[no description available] | 2.08 | 1 | 0 | N-arylpiperazine | |
[4-(2-pyrimidinyl)-1-piperazinyl]-[1-[4-(2-pyrimidinyl)-1-piperazinyl]-4-isoquinolinyl]methanone
[no description available] | 2.08 | 1 | 0 | piperazines;
pyridines | |
N-[[4-(dimethylamino)phenyl]methyl]-3-ethyl-N-(2-furanylmethyl)-5-methyl-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide
[no description available] | 2.08 | 1 | 0 | organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | |
N-(2,3-dimethylphenyl)-3-methyl-5-(4-morpholinylsulfonyl)-2-benzofurancarboxamide
[no description available] | 2.08 | 1 | 0 | aromatic amide;
furans | |
N-[(2-methyl-4-thiazolyl)methyl]-4-phenoxybenzenesulfonamide
[no description available] | 2.08 | 1 | 0 | aromatic ether | |
4-[[3-[(2-furanylmethylamino)-oxomethyl]-7-methoxy-1-benzopyran-2-ylidene]amino]benzoic acid
[no description available] | 2.08 | 1 | 0 | 1-benzopyran | |
N-(2-furanylmethyl)-1-[2-(2-hydroxyethoxy)ethyl]-2-imino-10-methyl-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamide
[no description available] | 2.08 | 1 | 0 | pyridopyrimidine | |
1-(2,1,3-benzothiadiazol-4-ylsulfonyl)-N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-piperidinecarboxamide
[no description available] | 2.08 | 1 | 0 | benzodioxine | |
4-[4-oxo-2-[[2-oxo-2-[(phenylmethyl)amino]ethyl]thio]-3-quinazolinyl]-1-piperidinecarboxylic acid ethyl ester
[no description available] | 2.08 | 1 | 0 | quinazolines | |
8-(2-propoxyphenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one
[no description available] | 2.08 | 1 | 0 | quinolines | |
alpha-chymotrypsin
Chymotrypsin: A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side. | 2.42 | 2 | 0 | | |
N-[4-[5-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]-4-pyridinecarboxamide
[no description available] | 2.08 | 1 | 0 | aromatic amide | |
7-lysylalanyl-4-methylcoumarinamide
7-lysylalanyl-4-methylcoumarinamide: fluorogenic substrate for dipeptidyl aminopeptidase | 1.98 | 1 | 0 | | |
3-(5,7-diphenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-1-propanol
[no description available] | 2.08 | 1 | 0 | triazolopyrimidines | |
fraxetin
fraxetin : A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups. | 2.15 | 1 | 0 | aromatic ether;
hydroxycoumarin | anti-inflammatory agent;
antibacterial agent;
antimicrobial agent;
antioxidant;
apoptosis inducer;
apoptosis inhibitor;
Arabidopsis thaliana metabolite;
hepatoprotective agent;
hypoglycemic agent |
hymecromone
Hymecromone: A coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID. | 1.97 | 1 | 0 | hydroxycoumarin | antineoplastic agent;
hyaluronic acid synthesis inhibitor |
daphnetin
[no description available] | 3.63 | 2 | 0 | hydroxycoumarin | |
methysergide maleate
[no description available] | 2.08 | 1 | 0 | ergoline alkaloid | |
esculetin
esculetin: used in filters for absorption of ultraviolet light; structure. esculetin : A hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light. | 2.15 | 1 | 0 | hydroxycoumarin | antioxidant;
plant metabolite;
ultraviolet filter |
7-hydroxycoumarin
7-oxycoumarin: derivatives have anti-oxidant properties. umbelliferone : A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7. | 2.15 | 1 | 0 | hydroxycoumarin | fluorescent probe;
food component;
plant metabolite |
morin
morin: a light yellowish pigment found in the wood of old fustic (Chlorophora tinctoria). morin : A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5. | 2.08 | 1 | 0 | 7-hydroxyflavonol;
pentahydroxyflavone | angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent |
N-(4-bromo-3-methylphenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
[no description available] | 2.08 | 1 | 0 | triazolopyrimidines | |
4-[[[2-(4-methoxyphenyl)-3-oxo-1H-isoindol-4-yl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester
[no description available] | 2.08 | 1 | 0 | isoindoles | |
1,5-dimethyl-4-oxo-N-[2-(3-thiophenyl)ethyl]-2-pyrrolo[3,2-c]quinolinecarboxamide
[no description available] | 2.08 | 1 | 0 | pyrroloquinoline | |
4-[[[1-[[2-(3-chlorophenyl)-5-methyl-4-oxazolyl]methyl]-3-piperidinyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester
[no description available] | 2.08 | 1 | 0 | 1,3-oxazoles | |
1,5-dimethyl-4-oxo-N-[3-(4-propyl-1-piperazinyl)propyl]-2-pyrrolo[3,2-c]quinolinecarboxamide
[no description available] | 2.08 | 1 | 0 | pyrroloquinoline | |
4-(4-tetrazolo[1,5-a]quinoxalinyl)morpholine
[no description available] | 2.08 | 1 | 0 | quinoxaline derivative | |
4-methylesculetin
4-methylesculetin: has antiinflammatory activity. 6,7-dihydroxy-4-methylcoumarin : A hydroxycoumarin that is 4-methylcuomarin which is substituted by hydroxy groups at positions 3 and 4. A hyaluronan synthesis inhibitor. It has also been used as a fluorescent sensor to monitor the consumption of a boronic acid in Suzuki coupling reactions; fluorescence is readily detectable by the naked eye using a standard 365 nm UV lamp. | 3.21 | 1 | 0 | hydroxycoumarin | anti-inflammatory agent;
antioxidant;
hyaluronan synthesis inhibitor |
7,8-dihydroxy-4-methylcoumarin
7,8-dihydroxy-4-methylcoumarin: possess strong antioxidant and radical scavenging activities; structure in first source | 2.15 | 1 | 0 | hydroxycoumarin | |
sulfur
Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine. | 2.02 | 1 | 0 | chalcogen;
nonmetal atom | macronutrient |
7-hydroxy-4-trifluoromethylcoumarin
7-hydroxy-4-trifluoromethylcoumarin: structure given in first source | 2.06 | 1 | 0 | | |
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. | 2.45 | 2 | 0 | cysteinium | fundamental metabolite |
oxalates
Oxalates: Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure. | 2.71 | 3 | 0 | | |
nitrobestatin
[no description available] | 2.01 | 1 | 0 | | |
dicumarol
Dicumarol: An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases. | 2.06 | 1 | 0 | hydroxycoumarin | anticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
Hsp90 inhibitor;
vitamin K antagonist |
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. | 4.53 | 24 | 0 | benzenes;
hydroxycoumarin;
methyl ketone | |
4-hydroxycoumarin
2-hydroxychromone: structure | 2.06 | 1 | 0 | hydroxycoumarin | |
1-cyclopentyl-1-[(4-oxo-1H-quinazolin-2-yl)methyl]-3-(phenylmethyl)urea
[no description available] | 2.08 | 1 | 0 | quinazolines | |
7-hydroxyquinoline
7-hydroxyquinoline: structure in first source. quinolin-7-ol : A monohydroxyquinoline carrying a hydroxy substituent at position 7. | 2.08 | 1 | 0 | monohydroxyquinoline | |
carbobenzoxycarbonyl-l-phenylalanyl-l-alanine-d-diazomethane
benzyloxycarbonylphenylalanylalanine diazomethyl ketone: selective inhibitor of thiol proteinases | 1.97 | 1 | 0 | | |