Page last updated: 2024-12-06

2-(4-aminophenyl)ethylamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-(4-aminophenyl)ethylamine, also known as phenethylamine, is a naturally occurring organic compound that serves as a precursor to several neurotransmitters. It is synthesized in the body from the amino acid phenylalanine. Phenethylamine has been shown to have a variety of effects on the central nervous system, including stimulating the release of dopamine and norepinephrine. It is also believed to play a role in mood regulation and cognitive function. Phenethylamine is being studied for its potential therapeutic applications in the treatment of conditions such as depression, ADHD, and Parkinson's disease. It is also being investigated for its potential use as a nootropic to enhance cognitive function.'

2-(4-aminophenyl)ethylamine: used to prepare derivatives of reducing oligosaccharides; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID72895
CHEMBL ID1650241
SCHEMBL ID143553
MeSH IDM0160449

Synonyms (49)

Synonym
2-(4-aminophenyl)ethylamine
4-amino-.beta.-phenylethylamine
p-aminophenethylamine
13472-00-9
4-(2-aminoethyl)aniline
nsc299558
nsc-299558
inchi=1/c8h12n2/c9-6-5-7-1-3-8(10)4-2-7/h1-4h,5-6,9-10h
4-(2-aminoethyl)aniline, 97%
4-aminophenethylamine
1-amino-2-(4-aminophenyl)ethane
4-(2-amino-ethyl)-phenylamine
4-aminophenylethylamine
FT-0650483
4-(2-aminoethyl)benzenamine;4-(2-amino-ethyl)-aniline
CHEMBL1650241
AKOS009156811
4-(2-amino-ethyl)-aniline
[4-(2-amino-ethyl)-phenyl]-amine
nsc 299558
einecs 236-739-2
4-(2-aminoethyl)phenylamine
FT-0602361
AB00936
SCHEMBL143553
2-(4-aminophenyl)ethyl amine
2-[4-(amino)phenyl]ethylamine
4-aminoethylaniline
4-(2-amino-ethyl)-phenyl amine
4-(2-aminoethyl)benzenamine
2-(4-amino-phenyl)-ethylamine
4-(2-aminoethyl)aniline #
benzeneethanamine, 4-amino-
.beta.-[4-aminophenyl]ethylamine
Q-102407
DTXSID30158902
mfcd00008194
4-(2-aminoethyl)-phenylamine
p-aminophenylethylamine
CS-W021984
X34DV3E856
beta-(4-aminophenyl)ethylamine
4-aminobenzeneethanamine
2-(p-aminophenyl)ethylamine
phenethylamine, p-amino-
DS-13659
AMY31595
4-aminophenyl ethylamine
EN300-170649
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID554321Inhibition of Leishmania major PTR1 at 500 uM2011Journal of medicinal chemistry, Jan-13, Volume: 54, Issue:1
Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.90

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.90 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.90)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]