Page last updated: 2024-08-07 13:19:40
P2Y purinoceptor 1
A P2Y purinoceptor 1 that is encoded in the genome of turkey. [OMA:P49652, PRO:DNx]
Synonyms
P2Y1;
6H1 orphan receptor;
ADP receptor;
Purinergic receptor
Research
Bioassay Publications (10)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (17)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues.Journal of medicinal chemistry, , Jan-12, Volume: 55, Issue:1, 2012
Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist.Journal of medicinal chemistry, , Sep-13, Volume: 55, Issue:17, 2012
2-MeS-beta,gamma-CCl2-ATP is a potent agent for reducing intraocular pressure.Journal of medicinal chemistry, , Apr-22, Volume: 53, Issue:8, 2010
Identification of hydrolytically stable and selective P2Y(1) receptor agonists.European journal of medicinal chemistry, , Volume: 44, Issue:4, 2009
Purine and pyrimidine (P2) receptors as drug targets.Journal of medicinal chemistry, , Sep-12, Volume: 45, Issue:19, 2002
Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists.Journal of medicinal chemistry, , May-09, Volume: 45, Issue:10, 2002
Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.Journal of medicinal chemistry, , May-06, Volume: 42, Issue:9, 1999
Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors.Journal of medicinal chemistry, , Jan-15, Volume: 41, Issue:2, 1998
Purine and pyrimidine (P2) receptors as drug targets.Journal of medicinal chemistry, , Sep-12, Volume: 45, Issue:19, 2002
Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists.Journal of medicinal chemistry, , May-09, Volume: 45, Issue:10, 2002
Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.Journal of medicinal chemistry, , May-06, Volume: 42, Issue:9, 1999
Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors.Journal of medicinal chemistry, , Jan-15, Volume: 41, Issue:2, 1998