clopidogrel has been researched along with Sensitivity and Specificity in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.11) | 18.2507 |
| 2000's | 36 (40.00) | 29.6817 |
| 2010's | 53 (58.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, LL; Cong, YL; Deng, XL; Guan, J; Li, YR; Liu, QY; Tian, KP; Zheng, BX | 1 |
| Court, MH; Lee, PM; Lyngby, JG | 1 |
| Borczuk, P; Ornam, JV; Pruitt, P | 1 |
| Backman, JT; Evangelista, EA; Filppula, AM; Kahma, H; Launiainen, T; Neuvonen, M; Totah, RA; Viinamäki, J | 1 |
| Nalawade, V; Vora, A | 1 |
| Cannatà, A; Cavallari, I; D'Ambrosio, A; Di Sciascio, G; Dicuonzo, G; Mangiacapra, F; Patti, G; Ricottini, E; Vizzi, V | 1 |
| Karnabatidis, D; Katsanos, K; Kitrou, P; Pastromas, G; Siablis, D; Spiliopoulos, S | 1 |
| Cui, G; Ding, H; Li, Z; Wang, DW; Wang, H; Zhang, L | 1 |
| Abtan, J; Barthélémy, O; Beygui, F; Brugier, D; Collet, JP; Kerneis, M; Montalescot, G; O'Connor, SA; Silvain, J; Vignalou, JB | 1 |
| Baber, U; Bander, J; Desnick, RJ; Hulot, JS; Kornreich, R; Martis, S; Scott, SA; Tan, Q; Yang, Y | 1 |
| Dhillon, K; Dovlatova, N; Fox, SC; Glenn, JR; Heptinstall, S; White, AE | 1 |
| Angiolillo, DJ; Baker, BA; Heiselman, DE; Jakubowski, JA; Li, W; Price, MJ | 1 |
| Chen, D; Jaffe, AS; Karon, BS; Koch, CD; Lingineni, RK; Miller, RS; Pruthi, RK; Tolan, NV; Wockenfus, AM | 1 |
| Chang, KS; Choi, DH; Chung, JW; Hong, SP; Kang, SH; Ki, YJ; Kim, HH; Koh, YY; Lee, YM; Park, G | 1 |
| Adyaman, Ş; Altaş, Y; Altndağ, R; Altntaş, B; Baysal, E; Çetin, M; Kaya, İ; Sevuk, U; Yaylak, B | 1 |
| Huang, L; Lai, X; Li, W; Xiong, Z; Xu, A; Zhang, S | 1 |
| Drwiła, R; Hymczak, H; Litwinowicz, R; Mazur, P; Plicner, D; Stoliński, J; Undas, A | 1 |
| Alfredsson, J; Gustafsson, KM; Janzon, M; Jonasson, L; Lindahl, TL; Logander, E; Nilsson, L; Swahn, E | 1 |
| Binns, C; Hoffman, BT; Hua, W; Lesslie, M; Mulvana, D | 1 |
| Brand, A; Bruggemans, EF; Eikenboom, J; Gielen, CL; Klautz, RJ; Stijnen, T; Tavilla, G | 1 |
| Brandt, CA; Dziura, J; Ebisu, KA; Finta, LA; Jovin, IS; Natale, D; Oprea, AD; Wackers, FJ | 1 |
| Braun, D; Braun, S; Hausleiter, J; Kastrati, A; Knipper, A; Massberg, S; Mehilli, J; Orban, M; Petzold, T; Schulz, S; Sibbing, D | 1 |
| Aisu, H; Hamada, M; Higashi, H; Hitsumoto, T; Ikeda, S; Inaba, S; Morofuji, T; Ohshima, K; Saito, M; Sumimoto, T; Takahashi, K | 1 |
| Ban, SP; Bang, JS; Chinh, ND; Hwang, G; Kim, CH; Kim, T; Kwon, OK; Oh, CW; Tjahjadi, M | 1 |
| Bergmeijer, TO; Breet, NJ; Godschalk, TC; Hackeng, CM; Janssen, PW; Kelder, JC; Le, TT; Ten Berg, JM | 1 |
| Castillo-Moreno, JA; Conesa-Zamora, P; Consuegra-Sánchez, L; García de Guadiana, L; García-Lagunar, MH; Melgarejo-Moreno, A; Ruiz-Cosano, J; Soria-Arcos, F; Vivar, PC | 1 |
| Dieplinger, B; Haltmayer, M; Mueller, T; Poelz, W | 1 |
| Garcia-Rinaldi, RF; Macdonald, RJ; McKellar, SH; Schaff, HV; Sundt, TM; Thompson, JL | 1 |
| Christ, G; Jilma, B; Lang, I; Siller-Matula, JM | 1 |
| Fayed, AS; Hassan, NY; Hoogmartens, J; Pauwels, J; Shehata, MA; Van Schepdael, A; Weshahy, SA | 1 |
| Price, MJ | 1 |
| Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Seidinger, D; Steiner, S | 1 |
| Jennings, LK | 1 |
| Ebina, T; Hashiba, K; Hibi, K; Kimura, K; Kiyokuni, M; Komura, N; Kosuge, M; Morita, S; Nakayama, N; Umemura, S | 1 |
| Esposito, RA | 1 |
| Kamath, N; Kristjansson, F; Manjunath Swamy, J; Radha Shekar, AK; Srinivas, NR | 1 |
| Berg, JM; Bouman, HJ; Elsenberg, EH; Hackeng, CM; van de Wal, RM; van Werkum, JW; Verheugt, FW; Zomer, AC | 1 |
| Hjemdahl, P; Jørgensen, L; Malmström, RE; Ostergren, J | 1 |
| Cowen, M; Goraya, TY; Poppe, T; Singal, B; Srikanth, A | 1 |
| Christ, G; Delle-Karth, G; Huber, K; Jilma, B; Lang, IM; Siller-Matula, JM | 1 |
| Bidet, A; Coste, P; Jais, C; Jakubowski, J; Nurden, A; Nurden, P; Puymirat, E | 1 |
| Han, MH; Kang, HS; Kim, JE; Kwon, BJ | 1 |
| Boulanger, J; Doutrelan, L; Elmkies, F; Luycx-Bore, A; Malaquin, D; Meimoun, P; Tribouilloy, C; Zemir, H | 1 |
| Bronze, Mdo R; Serra, H; Simplício, AL | 1 |
| Basset, T; Delavenne, X; Laporte, S; Malouk, N; Mismetti, P; Zufferey, P | 1 |
| Barthélémy, O; Bellemain-Appaix, A; Beygui, F; Cayla, G; Collet, JP; Hulot, JS; Montalescot, G; Pena, A; Silvain, J | 1 |
| Bal Dit Sollier, C; Berge, N; Boval, B; Drouet, L; Dubar, M | 1 |
| Christ, G; Herkner, H; Huber, K; Jilma, B; Kubica, J; Schrör, K; Siller-Matula, JM | 1 |
| Bauersachs, J; Flierl, U; Kobsar, AL; Koessler, J; Pfoertsch, S; Rajkovic, MS; Rechner, AR; Schafer, A; Steigerwald, U; Walter, U | 1 |
| Ebina, T; Endo, M; Hibi, K; Ishikawa, T; Iwahashi, N; Kimura, K; Kosuge, M; Maejima, N; Morita, S; Okada, K; Umemura, S | 1 |
| Ara, R; Cooper, K; Fairbank, E; Palmer, S; Raftery, J; Turner, D; Ward, S | 1 |
| Ali, KA; Arayne, MS; Nawaz, M; Sultana, N | 1 |
| Brasseur, D; Bremond, N; Delesque Touchard, N; Hurbin, F; Lavisse, M; Rouchon, MC; Roy, S; Savi, P; Schofield, J; Sultan, E; Tuffal, G | 1 |
| Kukin, M; Messerli, FH | 1 |
| Fritsma, GA; McGlasson, DL; Shah, AD | 1 |
| Anderson, DK; Buchan, BW; Cogbill, CH; Jannetto, PJ; Ledeboer, NA; Ledford, JS; Peterson, JF; Quigley, NB; White, MN | 1 |
| Connolly, SJ; de Caterina, R; Eikelboom, JW; Hart, RG; Hirsh, J; Hohnloser, S; Ng, J; Pogue, J; Yusuf, S | 1 |
| Figg, WD; Horenstein, RB; Pacanowski, MA; Peer, CJ; Spencer, SD; VanDenBerg, DA | 1 |
| Delle-Karth, G; Grzybowski, T; Huber, K; Jilma, B; Kozinski, M; Kubica, J; Lang, IM; Linkowska, K; Maurer, G; Neunteufl, T; Siller-Matula, JM | 1 |
| Bellomo, G; Cassani, C; Manzini, M; Parrella, M; Pergolini, P; Portalupi, MR; Prando, MD; Rolla, R; Serino, R; Vidali, M | 1 |
| Kim, MH; Yu, LH; Zhang, HZ | 1 |
| Chang, K; Jang, J; Kim, J; Kim, M; Kim, Y; Lim, J; Park, HI; Shin, S | 1 |
| Ang, L; Ilapakurti, M; Lee, MS; Mahmud, E; Palakodeti, V; Thani, KB | 1 |
| Elsinghorst, PW | 1 |
| Owens, DK; Schleinitz, MD; Weiss, JP | 1 |
| Dyszkiewicz-Korpanty, AM; Frenkel, EP; Sarode, R | 1 |
| Heidenreich, PA; Schleinitz, MD | 1 |
| Caro, J; Culler, S; Gabriel, S; Lamy, A; Mahoney, EM; Weintraub, WS; Yuan, Y; Yusuf, S | 1 |
| Barot, D; Lohray, VB; Mohan, PR; Sharma, K; Singh, SS | 1 |
| Carroll, RC; Chavez, JJ; Craft, RM; Muenchen, RA; Snider, CC | 1 |
| Graff, J; Harder, S | 1 |
| Grayson, AD; Lowe, R; Moore, RK; Morris, JL; Perry, RA; Stables, RH | 1 |
| Dalvandi, A; Jalalizadeh, H; Kebriaee-Zadeh, A; Shekarchi, M; Souri, E | 1 |
| Danikiewicz, W; Swist, M | 1 |
| Shin, BS; Yoo, SD | 1 |
| Abbate, R; Antonucci, E; Fedi, S; Gensini, GF; Giglioli, C; Gori, AM; Marcucci, R; Paniccia, R; Poli, S; Prisco, D; Romano, E; Valente, S | 1 |
| Buffa, M; Clerico, A; De Filippis, R; Della Pina, F; Gianetti, J; Rizza, A; Sbrana, S | 1 |
| Dyszkiewicz-Korpanty, A; Frenkel, EP; Olteanu, H; Sarode, R | 1 |
| Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bass, TA; Bernardo, E; Costa, MA; Escaned, J; Fernandez-Ortiz, A; Guzman, LA; Hernández-Antolin, R; Jimenez-Quevedo, P; Macaya, C; Moreno, R; Palazuelos, J; Sabaté, M | 1 |
| Alfonso, F; Angiolillo, DJ | 1 |
| Blindt, R; de Taeye, A; Hoffmann, R; Kelm, M; Kiefer, P; Müller, R; Stellbrink, K; Weber, C; Yagmur, E | 1 |
| Cairns, JA; Gent, M; Hirsh, J; Marler, J; Pogue, J; Pritchett, EL; Wittes, J; Wyse, DG | 1 |
| Einav, Y; Fefer, P; Hod, H; Lubetsky, A; Matetzky, S; Savion, N; Shenkman, B; Varon, D | 1 |
| Lindhoff-Last, E; Linnemann, B; Mani, H; Prochnow, S; Schwonberg, J | 1 |
| Bahrami, G; Mohammadi, B; Sisakhtnezhad, S | 1 |
| FitzGerald, GA | 1 |
| Salonia, J | 1 |
| Andraws, R; Pannu, R | 1 |
| Bressolle, F; Lagorce, P; Necciari, J; Ortiz, J; Perez, Y | 1 |
| Calverley, DC | 1 |
9 review(s) available for clopidogrel and Sensitivity and Specificity
| Article | Year |
|---|---|
Monitoring platelet function to reduce the risk of ischemic and bleeding complications.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Hemorrhage; Humans; Ischemia; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2009 |
Variability in platelet response to the antiplatelet agents aspirin and clopidogrel: mechanisms, measurement, and clinical relevance.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Probability; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Ticlopidine; Treatment Outcome | 2009 |
Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis.
Topics: Alleles; Clopidogrel; Coronary Thrombosis; Cytochrome P-450 Enzyme System; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Sensitivity and Specificity; Stents; Ticlopidine | 2010 |
Impact of clopidogrel loading dose on clinical outcome in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Clopidogrel; Dose-Response Relationship, Drug; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2011 |
Quantitative determination of clopidogrel and its metabolites in biological samples: a mini-review.
Topics: Chromatography, Liquid; Clopidogrel; Humans; Sensitivity and Specificity; Tandem Mass Spectrometry; Ticlopidine | 2013 |
Monitoring the ACTIVE-W trial: some issues in monitoring a noninferiority trial.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clinical Trials Data Monitoring Committees; Clopidogrel; Decision Making; Female; Humans; Irbesartan; Male; Prognosis; Randomized Controlled Trials as Topic; Research Design; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Tetrazoles; Ticlopidine; Treatment Outcome | 2008 |
Translational therapeutics at the platelet vascular interface. Summary.
Topics: Angina, Unstable; Animals; Aspirin; Blood Platelets; Clopidogrel; Disease Models, Animal; Drug Evaluation, Preclinical; Education, Medical, Continuing; Humans; Mice; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Sensitivity and Specificity; Survival Analysis; Ticlopidine; Treatment Outcome | 2008 |
Effects of glycoprotein IIb/IIIa inhibitors in patients undergoing percutaneous coronary intervention after pretreatment with clopidogrel: a meta-analysis of randomized trials.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Clopidogrel; Confidence Intervals; Coronary Angiography; Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunoglobulin Fab Fragments; Male; Odds Ratio; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Ticlopidine; Treatment Outcome | 2008 |
Antiplatelet therapy in the elderly. Aspirin, ticlopidine-clopidogrel, and GPIIb/GPIIIa antagonists.
Topics: Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Sensitivity and Specificity; Thromboembolism; Ticlopidine; Treatment Outcome | 2001 |
13 trial(s) available for clopidogrel and Sensitivity and Specificity
| Article | Year |
|---|---|
Detecting a thienopyridine effect by platelet reactivity assessment and its implications for risk stratification.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Point-of-Care Systems; Prasugrel Hydrochloride; Pyridines; Receptors, Purinergic P2Y12; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Preoperative platelet aggregation predicts perioperative blood loss and rethoracotomy for bleeding in patients receiving dual antiplatelet treatment prior to coronary surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Drug Combinations; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Hemorrhage; Premedication; Prognosis; Reoperation; Reproducibility of Results; Sensitivity and Specificity; Thoracic Surgery; Thrombosis; Ticlopidine; Treatment Outcome | 2015 |
Large early variation of residual platelet reactivity in Acute Coronary Syndrome patients treated with clopidogrel: results from Assessing Platelet Activity in Coronary Heart Disease (APACHE).
Topics: Acute Coronary Syndrome; Aged; Clopidogrel; Female; Humans; Male; Platelet Aggregation; Platelet Count; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2015 |
Stopping antiplatelet medication before coronary artery bypass graft surgery: is there an optimal timing to minimize bleeding?
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Platelet Transfusion; Postoperative Hemorrhage; Prospective Studies; Risk Assessment; Sensitivity and Specificity; Ticlopidine; Time Factors; Treatment Outcome; Withholding Treatment | 2015 |
Platelet function and coagulation in patients with STEMI and peri-interventional clopidogrel plus heparin vs. prasugrel plus bivalirudin therapy (BRAVE 4 substudy).
Topics: Antithrombins; Clopidogrel; Drug Therapy, Combination; Female; Heparin; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity; Thrombelastography; Ticlopidine; Treatment Outcome | 2016 |
Comparison of methods to evaluate clopidogrel-mediated platelet inhibition after percutaneous intervention with stent implantation.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reproducibility of Results; Sensitivity and Specificity; Stents; Ticlopidine | 2009 |
Differential sensitivity and kinetics of response of different ex vivo tests monitoring functional variability of platelet response to clopidogrel.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Double-Blind Method; Flow Cytometry; Humans; Kinetics; Male; Microfilament Proteins; Nephelometry and Turbidimetry; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Thionucleotides; Thrombelastography; Ticlopidine; Young Adult | 2010 |
Net clinical benefit of adding clopidogrel to aspirin therapy in patients with atrial fibrillation for whom vitamin K antagonists are unsuitable.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Sensitivity and Specificity; Stroke; Ticlopidine; Vitamin K | 2011 |
Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coronary syndromes without ST-segment elevation.
Topics: Acute Disease; Aged; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Electrocardiography; Female; Follow-Up Studies; Humans; Length of Stay; Life Expectancy; Male; Medicare; Middle Aged; Myocardial Infarction; Patient Admission; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Sensitivity and Specificity; Syndrome; Ticlopidine; Time; Treatment Outcome; United States | 2005 |
Comparison of modified Thrombelastograph and Plateletworks whole blood assays to optical platelet aggregation for monitoring reversal of clopidogrel inhibition in elective surgery patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clopidogrel; Elective Surgical Procedures; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Preoperative Care; Reproducibility of Results; Sensitivity and Specificity; Thrombelastography; Ticlopidine | 2005 |
The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Research Design; Risk Assessment; Risk Factors; ROC Curve; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Variable responsiveness to clopidogrel and aspirin among patients with acute coronary syndrome as assessed by platelet function tests.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet-Rich Plasma; ROC Curve; Sensitivity and Specificity; Ticlopidine | 2008 |
High-performance liquid chromatographic determination of inactive carboxylic acid metabolite of clopidogrel in human serum: Application to a bioequivalence study.
Topics: Acetonitriles; Adult; Carboxylic Acids; Chromatography, High Pressure Liquid; Clopidogrel; Drug Stability; Ethylamines; Humans; Male; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Therapeutic Equivalency; Ticlopidine | 2008 |
68 other study(ies) available for clopidogrel and Sensitivity and Specificity
| Article | Year |
|---|---|
[Evaluation of PFA P2Y assay in monitoring platelet function in elderly patients with cardiovascular disease receiving clopidogrel treatment].
Topics: Biological Assay; Blood Coagulation Tests; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sensitivity and Specificity; Ticlopidine | 2016 |
Validation of a method for quantitation of the clopidogrel active metabolite, clopidogrel, clopidogrel carboxylic acid, and 2-oxo-clopidogrel in feline plasma.
Topics: Animals; Cats; Chromatography, High Pressure Liquid; Clopidogrel; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Ticlopidine | 2017 |
A Decision Instrument to Identify Isolated Traumatic Subdural Hematomas at Low Risk of Neurologic Deterioration, Surgical Intervention, or Radiographic Worsening.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Clopidogrel; Cohort Studies; Decision Support Techniques; Emergency Service, Hospital; Female; Glasgow Coma Scale; Hematoma, Subdural; Humans; Likelihood Functions; Male; Middle Aged; Neuroimaging; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Ticlopidine; Warfarin; Young Adult | 2017 |
Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8.
Topics: Amiodarone; Clopidogrel; Cytochrome P-450 CYP2C8; Gemfibrozil; Glucuronides; Humans; Kinetics; Microsomes, Liver; Phenelzine; Sensitivity and Specificity | 2019 |
Box-Behnken design directed optimization for sensitivity assessment of anti-platelet drugs.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Clopidogrel; Models, Chemical; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Ticlopidine | 2019 |
Correlation of platelet reactivity and C-reactive protein levels to occurrence of peri-procedural myocardial infarction in patients undergoing percutaneous coronary intervention (from the ARMYDA-CRP study).
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Biomarkers; C-Reactive Protein; Clopidogrel; Female; Humans; Incidence; Italy; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; Risk Factors; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2013 |
Platelet responsiveness to clopidogrel treatment after peripheral endovascular procedures: the PRECLOP study: clinical impact and optimal cutoff value of on-treatment high platelet reactivity.
Topics: Aged; Blood Platelets; Clopidogrel; Disease-Free Survival; Endovascular Procedures; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Stents; Ticlopidine; Treatment Outcome | 2013 |
Comparison of high-resolution melting analysis, TaqMan Allelic discrimination assay, and sanger sequencing for Clopidogrel efficacy genotyping in routine molecular diagnostics.
Topics: Adult; Alleles; Clopidogrel; Female; Humans; Male; Middle Aged; Molecular Diagnostic Techniques; Multilocus Sequence Typing; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2013 |
Identification of poor response to P2Y12 inhibitors in ACS patients with a new ELISA-based vasodilator-associated stimulated phosphoprotein (VASP) phosphorylation assay.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Cell Adhesion Molecules; Cell Separation; Clopidogrel; Enzyme-Linked Immunosorbent Assay; Feasibility Studies; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Piperazines; Platelet Function Tests; Prasugrel Hydrochloride; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Thiophenes; Ticlopidine | 2013 |
An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Base Sequence; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genetic Association Studies; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Prodrugs; Reference Standards; Sensitivity and Specificity; Sequence Analysis, DNA; Ticlopidine | 2013 |
'VASPFix' for measurement of VASP phosphorylation in platelets and for monitoring effects of P2Y12 antagonists.
Topics: Adenosine; Adenosine Diphosphate; Alprostadil; Biomarkers, Pharmacological; Blood Platelets; Bucladesine; Cell Adhesion Molecules; Cells, Cultured; Clopidogrel; Cyclic AMP; Humans; Iloprost; Microfilament Proteins; Phosphoproteins; Phosphorylation; Piperazines; Platelet Aggregation; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Reproducibility of Results; Sensitivity and Specificity; Thiophenes; Thrombophilia; Ticlopidine | 2014 |
Precision and reliability of 5 platelet function tests in healthy volunteers and donors on daily antiplatelet agent therapy.
Topics: Arachidonic Acid; Aspirin; Clopidogrel; Female; Healthy Volunteers; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2014 |
Relation between the Change in Mean Platelet Volume and Clopidogrel Resistance in Patients Undergoing Percutaneous Coronary Intervention.
Topics: Aged; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2015 |
Roles of the red cell distribution width and neutrophil/lymphocyte ratio in predicting thrombolysis failure in patients with an ST-segment elevation myocardial infarction.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Erythrocyte Indices; Female; Fibrinolytic Agents; Humans; Leukocyte Count; Lymphocyte Count; Male; Middle Aged; Myocardial Infarction; Neutrophils; Percutaneous Coronary Intervention; Prognosis; Retrospective Studies; ROC Curve; Salvage Therapy; Sensitivity and Specificity; Tenecteplase; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator; Treatment Failure | 2015 |
VASP phosphorylation and genetic polymorphism for clopidogrel resistance in Chinese patients with non-cardioembolic ischemic stroke.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Ischemia; Cell Adhesion Molecules; China; Clopidogrel; Drug Resistance; Female; Genetic Markers; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Prevalence; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Stroke; Ticlopidine; Treatment Failure; Young Adult | 2014 |
Development of a sensitive and fast UHPLC-MS/MS method for determination of clopidogrel, clopidogrel acid and clopidogrel active metabolite H4 in human plasma.
Topics: Blood Chemical Analysis; Calibration; Chromatography, High Pressure Liquid; Clopidogrel; Humans; Microsomes, Liver; Purinergic P2Y Receptor Antagonists; Sensitivity and Specificity; Stereoisomerism; Tandem Mass Spectrometry; Temperature; Ticlopidine | 2015 |
The influence of clopidogrel on ischemia diagnosed by myocardial perfusion stress testing.
Topics: Cardiotonic Agents; Clopidogrel; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardial Perfusion Imaging; Prevalence; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Ticlopidine; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2016 |
Usefulness of Intravascular Ultrasound for Predicting Risk of Intraprocedural Stent Thrombosis.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Ultrasonography, Interventional | 2016 |
P2Y
Topics: Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Thromboembolism; Ticlopidine; Treatment Outcome | 2017 |
The effect of correcting VerifyNow P2Y12 assay results for hematocrit in patients undergoing percutaneous coronary interventions.
Topics: Aged; Area Under Curve; Blood Platelets; Clopidogrel; Female; Follow-Up Studies; Hematocrit; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2Y12; Risk; ROC Curve; Sensitivity and Specificity; Thrombosis; Ticlopidine | 2017 |
Genotyping of six clopidogrel-metabolizing enzyme polymorphisms has a minor role in the assessment of platelet reactivity in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Blood Platelets; Clopidogrel; Coronary Angiography; Cross-Sectional Studies; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; ROC Curve; Sensitivity and Specificity | 2017 |
Utility of the PFA-100 instrument and the novel multiplate analyzer for the assessment of aspirin and clopidogrel effects on platelet function in patients with cardiovascular disease.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Collagen; Electric Impedance; Epinephrine; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Activation; Platelet Function Tests; Sensitivity and Specificity; Ticlopidine | 2009 |
Short- and long-term efficacy of aspirin and clopidogrel for thromboprophylaxis for mechanical heart valves: an in vivo study in swine.
Topics: Administration, Oral; Animals; Aspirin; Bioprosthesis; Clopidogrel; Dalteparin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Valve Prosthesis Implantation; Injections, Subcutaneous; Postoperative Care; Postoperative Complications; Random Allocation; Risk Factors; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate; Swine; Thromboembolism; Thrombolytic Therapy; Ticlopidine; Time Factors | 2008 |
Calcium-channel blockers reduce the antiplatelet effect of clopidogrel.
Topics: Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Dihydropyridines; Drug Interactions; Female; Flow Cytometry; Humans; Logistic Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Reference Values; Risk Assessment; Sensitivity and Specificity; Statistics, Nonparametric; Ticlopidine; Treatment Outcome | 2008 |
Separation and determination of clopidogrel and its impurities by capillary electrophoresis.
Topics: Buffers; Clopidogrel; Cyclodextrins; Drug Contamination; Electricity; Electrophoresis, Capillary; Ethylamines; Hydrogen-Ion Concentration; Molecular Structure; Platelet Aggregation Inhibitors; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Software; Stereoisomerism; Temperature; Ticlopidine | 2009 |
Early, accurate, non-invasive predictors of left main or 3-vessel disease in patients with non-ST-segment elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Electrocardiography; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prognosis; Retrospective Studies; Sensitivity and Specificity; Ticlopidine; Troponin T | 2009 |
Invited commentary.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Female; Graft Occlusion, Vascular; Graft Survival; Humans; Male; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Ticlopidine; Vascular Patency | 2009 |
Sensitivity enhancement and matrix effect evaluation during summation of multiple transition pairs-case studies of clopidogrel and ramiprilat.
Topics: Chromatography, Liquid; Clopidogrel; Humans; Ramipril; Sensitivity and Specificity; Tandem Mass Spectrometry; Ticlopidine | 2010 |
The influence of clinical characteristics, laboratory and inflammatory markers on 'high on-treatment platelet reactivity' as measured with different platelet function tests.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; Cells, Cultured; Clopidogrel; Drug Combinations; Female; Humans; Interleukin-6; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sensitivity and Specificity; Thrombosis; Ticlopidine | 2009 |
Poor performance with a platelet counting technique to monitor clopidogrel inhibitory effects in the point-of-care setting.
Topics: Clopidogrel; Humans; Platelet Aggregation Inhibitors; Platelet Count; Point-of-Care Systems; Reproducibility of Results; Sensitivity and Specificity; Sweden; Thrombosis; Ticlopidine | 2010 |
Is it possible to safely administer early a loading dose of clopidogrel before coronary angiography to patients who are candidates for percutaneous coronary intervention?
Topics: Acute Coronary Syndrome; Adult; Aged, 80 and over; Angioplasty, Balloon, Coronary; Clopidogrel; Cohort Studies; Coronary Angiography; Coronary Artery Bypass; Feasibility Studies; Female; Humans; Logistic Models; Male; Medical Records; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Predictive Value of Tests; Preoperative Care; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2009 |
Multiple electrode aggregometry predicts stent thrombosis better than the vasodilator-stimulated phosphoprotein phosphorylation assay.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Electrodes; Female; Humans; Logistic Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; ROC Curve; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
VerifyNow and VASP phosphorylation assays give similar results for patients receiving clopidogrel, but they do not always correlate with platelet aggregation.
Topics: Adult; Aged; Aged, 80 and over; Cell Adhesion Molecules; Clopidogrel; Female; Humans; Male; Microfilament Proteins; Middle Aged; Myocardial Infarction; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Thrombosis; Ticlopidine | 2010 |
Preinterventional clopidogrel response variability for coil embolization of intracranial aneurysms: clinical implications.
Topics: Aged; Blood Coagulation Tests; Clopidogrel; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Intracranial Thrombosis; Logistic Models; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Risk Factors; Sensitivity and Specificity; Ticlopidine | 2010 |
Non-invasive coronary flow reserve after successful primary angioplasty for acute anterior myocardial infarction is an independent predictor of left ventricular adverse remodelling.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Echocardiography; Female; Fractional Flow Reserve, Myocardial; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Risk Assessment; ROC Curve; Sensitivity and Specificity; Statistics as Topic; Stroke Volume; Ticlopidine; Ventricular Function, Left | 2010 |
Simultaneous determination of clopidogrel and its carboxylic acid metabolite by capillary electrophoresis.
Topics: Carboxylic Acids; Clopidogrel; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Least-Squares Analysis; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Temperature; Ticlopidine | 2010 |
Ultra-performance LC MS/MS method for quantification of clopidogrel active metabolite.
Topics: Chromatography, High Pressure Liquid; Clopidogrel; Humans; Molecular Structure; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Ticlopidine | 2010 |
The new INNOVANCE® PFA P2Y cartridge is sensitive to the detection of the P2Y₁₂ receptor inhibition.
Topics: Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Biological Assay; Biomarkers; Blood Platelets; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Sensitivity and Specificity; Ticlopidine; Young Adult | 2011 |
An early and simple predictor of severe left main and/or three-vessel disease in patients with non-ST-segment elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Biomarkers; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Early Diagnosis; Electrocardiography; Female; Heart Conduction System; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Ticlopidine; Treatment Outcome; Troponin T | 2011 |
The CHD challenge: comparing four cost-effectiveness models.
Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Models, Econometric; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine; United Kingdom | 2011 |
Simultaneous determination of clopidogrel and aspirin by RP-HPLC from bulk material and dosage formulations using multivariate calibration technique.
Topics: Aspirin; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Clopidogrel; Linear Models; Multivariate Analysis; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2011 |
An improved method for specific and quantitative determination of the clopidogrel active metabolite isomers in human plasma.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; CHO Cells; Chromatography, High Pressure Liquid; Clopidogrel; Cricetinae; Cricetulus; Humans; Mass Spectrometry; Phosphorus Isotopes; Plasma; Product Surveillance, Postmarketing; Protein Binding; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Stereoisomerism; Thionucleotides; Ticlopidine; Transgenes | 2011 |
Wireless pulmonary artery haemodynamic monitoring.
Topics: Anticoagulants; Aspirin; Clopidogrel; Electrodes, Implanted; Equipment Design; Female; Heart Failure; Hemodynamics; Humans; Male; Microchip Analytical Procedures; Monitoring, Physiologic; Pulmonary Artery; Pulmonary Wedge Pressure; Sensitivity and Specificity; Survival Analysis; Ticlopidine; Warfarin | 2011 |
Ability of the INNOVANCE PFA P2Y system to detect clopidogrel-induced ADP receptor blockade in preangiocath individuals.
Topics: Adult; Angiography; Blood Coagulation; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diagnostic Equipment; Drug Monitoring; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Ticlopidine; Young Adult | 2011 |
Evaluation of a microarray-based genotyping assay for the rapid detection of cytochrome P450 2C19 *2 and *3 polymorphisms from whole blood using nanoparticle probes.
Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Cytochrome P-450 CYP2C19; Genotype; Hematologic Tests; Humans; Nanospheres; Oligonucleotide Array Sequence Analysis; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine; Time Factors | 2011 |
A sensitive and rapid ultra HPLC-MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma.
Topics: Chromatography, High Pressure Liquid; Clopidogrel; Drug Stability; Humans; Reproducibility of Results; Sensitivity and Specificity; Sulfhydryl Compounds; Tandem Mass Spectrometry; Ticlopidine | 2012 |
Phenotyping vs. genotyping for prediction of clopidogrel efficacy and safety: the PEGASUS-PCI study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Austria; Blood Platelets; Cardiovascular Diseases; Cell Adhesion Molecules; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Hemorrhage; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Microfilament Proteins; Middle Aged; Multivariate Analysis; Pharmacogenetics; Phenotype; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Prospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Role of the laboratory in monitoring patients receiving dual antiplatelet therapy.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Clinical Laboratory Techniques; Clopidogrel; Drug Resistance; Female; Humans; Logistic Models; Male; Middle Aged; Monitoring, Physiologic; Multivariate Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Reproducibility of Results; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine | 2012 |
Effect of different anticoagulants on multiple electrode platelet aggregometry after clopidogrel and aspirin administration in patients undergoing coronary stent implantation: a comparison between citrate and hirudin.
Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Arachidonic Acid; Aspirin; Citric Acid; Clopidogrel; Female; Hirudins; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; ROC Curve; Sensitivity and Specificity; Stents; Ticlopidine | 2013 |
A comparison of INNOVANCE® PFA P2Y and VerifyNow P2Y12 assay for the assessment of clopidogrel resistance in patients undergoing percutaneous coronary intervention.
Topics: Adult; Aged; Aged, 80 and over; Cardiac Catheterization; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Statistics, Nonparametric; Ticlopidine | 2012 |
Elevated plasma fibrinogen rather than residual platelet reactivity after clopidogrel pre-treatment is associated with an increased ischemic risk during elective percutaneous coronary intervention.
Topics: Aged; Blood Platelets; C-Reactive Protein; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Female; Fibrinogen; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Predictive Value of Tests; Premedication; Prospective Studies; ROC Curve; Sensitivity and Specificity; Ticlopidine; Troponin | 2013 |
Clopidogrel versus aspirin for secondary prophylaxis of vascular events: a cost-effectiveness analysis.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Fibrinolytic Agents; Humans; Markov Chains; Middle Aged; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Ticlopidine; Vascular Diseases | 2004 |
Approach to the assessment of platelet function: comparison between optical-based platelet-rich plasma and impedance-based whole blood platelet aggregation methods.
Topics: Adolescent; Adult; Aspirin; Blood Platelets; Child; Clopidogrel; Diagnostic Tests, Routine; Electric Impedance; Humans; Male; Middle Aged; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Ticlopidine; Valproic Acid | 2005 |
A cost-effectiveness analysis of combination antiplatelet therapy for high-risk acute coronary syndromes: clopidogrel plus aspirin versus aspirin alone.
Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Computer Simulation; Cost-Benefit Analysis; Electrocardiography; Hemorrhage; Humans; Markov Chains; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Recurrence; Risk Factors; Sensitivity and Specificity; Stroke; Ticlopidine | 2005 |
Estimation of carboxylic acid metabolite of clopidogrel in Wistar rat plasma by HPLC and its application to a pharmacokinetic study.
Topics: Animals; Carboxylic Acids; Chromatography, High Pressure Liquid; Clopidogrel; Drug Stability; Male; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2005 |
Investigation of the PADA as a method for monitoring GPIIb/IIIa inhibitors and other antiplatelet agents.
Topics: Abciximab; Adenosine Monophosphate; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Eptifibatide; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Sensitivity and Specificity; Ticlopidine | 2005 |
A study comparing the incidence and predictors of creatine kinase MB and troponin T release after coronary angioplasty. Does Clopidogrel preloading reduce myocardial necrosis following elective percutaneous coronary intervention?
Topics: Angioplasty, Balloon, Coronary; Biomarkers; Clopidogrel; Cohort Studies; Coronary Disease; Creatine Kinase, MB Form; Elective Surgical Procedures; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardium; Necrosis; Platelet Aggregation Inhibitors; Preoperative Care; Sensitivity and Specificity; Ticlopidine; Troponin T; United Kingdom | 2007 |
Validated HPLC method for determination of carboxylic acid metabolite of clopidogrel in human plasma and its application to a pharmacokinetic study.
Topics: Adult; Carboxylic Acids; Chromatography, High Pressure Liquid; Clopidogrel; Humans; Male; Platelet Aggregation Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2006 |
The fragmentation reactions of anti-platelet drugs: clopidogrel and ticlopidine.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Clopidogrel; Platelet Aggregation Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Therapeutic Equivalency; Ticlopidine | 2007 |
Determination of clopidogrel in human plasma by liquid chromatography/tandem mass spectrometry: application to a clinical pharmacokinetic study.
Topics: Adult; Chromatography, Liquid; Clopidogrel; Humans; Male; Platelet Aggregation Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Ticlopidine | 2007 |
Comparison of different methods to evaluate the effect of aspirin on platelet function in high-risk patients with ischemic heart disease receiving dual antiplatelet treatment.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Sensitivity and Specificity; Ticlopidine | 2007 |
Relationships between optical aggregometry (type born) and flow cytometry in evaluating ADP-induced platelet activation.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Dual Specificity Phosphatase 2; Female; Flow Cytometry; Humans; Image Cytometry; Male; Microfilament Proteins; Middle Aged; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2008 |
Clopidogrel anti-platelet effect: an evaluation by optical aggregometry, impedance aggregometry, and the platelet function analyzer (PFA-100).
Topics: Adult; Aged; Clopidogrel; Female; Hematologic Tests; Humans; Male; Middle Aged; Optics and Photonics; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sensitivity and Specificity; Ticlopidine | 2007 |
Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease.
Topics: Aged; Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Multivariate Analysis; Myocardial Infarction; Outcome Assessment, Health Care; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prognosis; Prospective Studies; Renal Insufficiency; ROC Curve; Sensitivity and Specificity; Stroke; Ticlopidine | 2007 |
Platelet function testing and cardiovascular outcomes: steps forward in identifying the best predictive measure.
Topics: Adenosine Diphosphate; Cardiovascular Diseases; Clopidogrel; Flow Cytometry; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prognosis; Pyridines; ROC Curve; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2007 |
Standardization of light transmittance aggregometry for monitoring antiplatelet therapy: an adjustment for platelet count is not necessary.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Algorithms; Arachidonic Acid; Aspirin; Calibration; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Platelet-Rich Plasma; Sensitivity and Specificity; Thrombophilia; Ticlopidine | 2008 |
Common blood thinners: what are the differences?
Topics: Anticoagulants; Aspirin; Clopidogrel; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug Utilization; Emergency Nursing; Emergency Service, Hospital; Humans; Monitoring, Physiologic; Risk Assessment; Sensitivity and Specificity; Ticlopidine; Warfarin | 2008 |
Assay method for the carboxylic acid metabolite of clopidogrel in human plasma by gas chromatography-mass spectrometry.
Topics: Calibration; Carboxylic Acids; Clopidogrel; Gas Chromatography-Mass Spectrometry; Humans; Platelet Aggregation Inhibitors; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 1998 |