Page last updated: 2024-08-07 16:13:30
Dihydrofolate reductase
[no definition available]
Synonyms
EC 1.5.1.3
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (5)
Drugs with Inhibition Measurements
In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.Bioorganic & medicinal chemistry, , Jul-15, Volume: 17, Issue:14, 2009
Folate-synthesizing enzyme system as target for development of inhibitors and inhibitor combinations against Candida albicans-synthesis and biological activity of new 2,4-diaminopyrimidines and 4'-substituted 4-aminodiphenyl sulfones.Journal of medicinal chemistry, , Jan-01, Volume: 47, Issue:1, 2004
Selective inhibitors of Candida albicans dihydrofolate reductase: activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines.Journal of medicinal chemistry, , Sep-01, Volume: 38, Issue:18, 1995
High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.Journal of medicinal chemistry, , Feb-16, Volume: 39, Issue:4, 1996
Selective inhibitors of Candida albicans dihydrofolate reductase: activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines.Journal of medicinal chemistry, , Sep-01, Volume: 38, Issue:18, 1995
High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.Journal of medicinal chemistry, , Feb-16, Volume: 39, Issue:4, 1996
Selective inhibitors of Candida albicans dihydrofolate reductase: activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines.Journal of medicinal chemistry, , Sep-01, Volume: 38, Issue:18, 1995