| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Acute Confusional Senile Dementia
[description not available] | 0 | 5.86 | 12 | 0 |
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 5.86 | 12 | 0 |
Breast Cancer
[description not available] | 0 | 3.62 | 8 | 0 |
Metastase
[description not available] | 0 | 2.08 | 1 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 3.62 | 8 | 0 |
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.08 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 5.97 | 13 | 0 |
Experimental Mammary Neoplasms
[description not available] | 0 | 2.57 | 2 | 0 |
Invasiveness, Neoplasm
[description not available] | 0 | 3.02 | 4 | 0 |
Hematologic Malignancies
[description not available] | 0 | 2.41 | 1 | 0 |
Hematologic Neoplasms
Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. | 0 | 2.41 | 1 | 0 |
Libman-Sacks Disease
[description not available] | 0 | 2.6 | 1 | 0 |
Lupus Erythematosus, Systemic
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. | 0 | 2.6 | 1 | 0 |
Benign Neoplasms
[description not available] | 0 | 6.96 | 6 | 0 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 6.96 | 6 | 0 |
Lung Injury, Acute
[description not available] | 0 | 3.99 | 1 | 1 |
Acute Lung Injury
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). | 0 | 3.99 | 1 | 1 |
Prediabetes
[description not available] | 0 | 3.99 | 1 | 1 |
Obesity
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 3.99 | 1 | 1 |
Prediabetic State
The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 3.99 | 1 | 1 |
ER-Negative PR-Negative HER2-Negative Breast Cancer
[description not available] | 0 | 3.01 | 3 | 0 |
Triple Negative Breast Neoplasms
Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN. | 0 | 3.01 | 3 | 0 |
Cerebral Primitive Neuroectodermal Tumor
[description not available] | 0 | 3.12 | 1 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 3.55 | 2 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 3.55 | 2 | 0 |
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 3.12 | 1 | 0 |
Neuroectodermal Tumors, Primitive
A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059) | 0 | 3.12 | 1 | 0 |
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 2.66 | 2 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 7.39 | 10 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 7.39 | 10 | 0 |
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 2.61 | 2 | 0 |
Disease Exacerbation
[description not available] | 0 | 2.25 | 1 | 0 |
Adenocarcinoma, Basal Cell
[description not available] | 0 | 2.25 | 1 | 0 |
Cancer of Lung
[description not available] | 0 | 2.58 | 2 | 0 |
Adenocarcinoma
A malignant epithelial tumor with a glandular organization. | 0 | 2.25 | 1 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 2.58 | 2 | 0 |
Menstruation, Painful
[description not available] | 0 | 2.25 | 1 | 0 |
Colicky Pain
[description not available] | 0 | 2.25 | 1 | 0 |
Dysmenorrhea
Painful menstruation. | 0 | 2.25 | 1 | 0 |
Abdominal Pain
Sensation of discomfort, distress, or agony in the abdominal region. | 0 | 2.25 | 1 | 0 |
Acute Brain Injuries
[description not available] | 0 | 2.31 | 1 | 0 |
Brain Injuries
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. | 0 | 2.31 | 1 | 0 |
Chronic Kidney Diseases
[description not available] | 0 | 2.31 | 1 | 0 |
Azotaemia
[description not available] | 0 | 2.31 | 1 | 0 |
Albuminuria
The presence of albumin in the urine, an indicator of KIDNEY DISEASES. | 0 | 2.31 | 1 | 0 |
Renal Insufficiency, Chronic
Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002) | 0 | 2.31 | 1 | 0 |
Amyloid Deposits
[description not available] | 0 | 2.31 | 1 | 0 |
Hepatocellular Carcinoma
[description not available] | 0 | 2.54 | 2 | 0 |
Cancer of Liver
[description not available] | 0 | 2.54 | 2 | 0 |
Colorectal Cancer
[description not available] | 0 | 2.15 | 1 | 0 |
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 2.54 | 2 | 0 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 2.54 | 2 | 0 |
Colorectal Neoplasms
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 2.15 | 1 | 0 |
Encephalopathy, Traumatic
[description not available] | 0 | 2.17 | 1 | 0 |
Brain Injuries, Traumatic
A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain. | 0 | 2.17 | 1 | 0 |
Cancer of Skin
[description not available] | 0 | 3.77 | 3 | 0 |
Skin Neoplasms
Tumors or cancer of the SKIN. | 0 | 3.77 | 3 | 0 |
Degenerative Diseases, Central Nervous System
[description not available] | 0 | 3.5 | 2 | 0 |
Neurodegenerative Diseases
Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 3.5 | 2 | 0 |
Leishmaniasis, American
[description not available] | 0 | 2.17 | 1 | 0 |
Leishmaniasis, Cutaneous
An endemic disease that is characterized by the development of single or multiple localized lesions on exposed areas of skin that typically ulcerate. The disease has been divided into Old and New World forms. Old World leishmaniasis is separated into three distinct types according to epidemiology and clinical manifestations and is caused by species of the L. tropica and L. aethiopica complexes as well as by species of the L. major genus. New World leishmaniasis, also called American leishmaniasis, occurs in South and Central America and is caused by species of the L. mexicana or L. braziliensis complexes. | 0 | 2.17 | 1 | 0 |
Alloxan Diabetes
[description not available] | 0 | 2.17 | 1 | 0 |
Asymmetric Diabetic Proximal Motor Neuropathy
[description not available] | 0 | 2.17 | 1 | 0 |
Allodynia
[description not available] | 0 | 2.17 | 1 | 0 |
Nerve Pain
[description not available] | 0 | 2.17 | 1 | 0 |
Diabetic Neuropathies
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325) | 0 | 2.17 | 1 | 0 |
Neuralgia
Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve. | 0 | 2.17 | 1 | 0 |
Cardiovascular Diseases
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 4.81 | 2 | 0 |
Arthritis, Degenerative
[description not available] | 0 | 2.17 | 1 | 0 |
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 2.17 | 1 | 0 |
Erythema
Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes. | 0 | 3.12 | 1 | 0 |
Diabetes Mellitus, Adult-Onset
[description not available] | 0 | 2.21 | 1 | 0 |
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 2.21 | 1 | 0 |
Kahler Disease
[description not available] | 0 | 2.08 | 1 | 0 |
Multiple Myeloma
A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. | 0 | 2.08 | 1 | 0 |
Bone Loss, Perimenopausal
[description not available] | 0 | 2.1 | 1 | 0 |
Osteoporosis, Postmenopausal
Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency. | 0 | 2.1 | 1 | 0 |
Dysplastic Nevus Syndrome, Hereditary
[description not available] | 0 | 2.13 | 1 | 0 |
Malignant Melanoma
[description not available] | 0 | 2.54 | 2 | 0 |
Melanoma
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) | 0 | 2.54 | 2 | 0 |
Angiogenesis, Pathologic
[description not available] | 0 | 2.5 | 2 | 0 |
Autoimmune Disease
[description not available] | 0 | 3.09 | 1 | 0 |
Autoimmune Diseases
Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. | 0 | 3.09 | 1 | 0 |
Tauopathies
Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration. | 0 | 2.05 | 1 | 0 |
Brain Inflammation
[description not available] | 0 | 2.05 | 1 | 0 |
Encephalitis
Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition. | 0 | 2.05 | 1 | 0 |
Cell Transformation, Neoplastic
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. | 0 | 2.06 | 1 | 0 |
Cancer of Prostate
[description not available] | 0 | 2.06 | 1 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.06 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 2.45 | 2 | 0 |
Diseases of Pharynx
[description not available] | 0 | 2.03 | 1 | 0 |