reserpine has been researched along with Sensitivity and Specificity in 20 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reserpine and the I." | 1.31 | Quantitative liquid chromatographic-tandem mass spectrometric determination of reserpine in FVB/N mouse plasma using a "chelating" agent (disodium EDTA) for releasing protein-bound analytes during 96-well liquid-liquid extraction. ( Henion, J; Ke, J; Lowes, S; Yancey, M; Zhang, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 15 (75.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Zhang, H | 1 |
| Zhong, D | 1 |
| Zhang, Z | 1 |
| Dai, X | 1 |
| Chen, X | 1 |
| Malcolm, A | 1 |
| Wright, S | 1 |
| Syms, RR | 1 |
| Moseley, RW | 1 |
| O'Prey, S | 1 |
| Dash, N | 1 |
| Pegus, A | 1 |
| Crichton, E | 1 |
| Hong, G | 1 |
| Holmes, AS | 1 |
| Finlay, A | 1 |
| Edwards, P | 1 |
| Hamilton, SE | 1 |
| Welch, CJ | 1 |
| Sogno, I | 1 |
| Conti, M | 1 |
| Consonni, P | 1 |
| Noonan, DM | 1 |
| Albini, A | 1 |
| Arruda, AF | 1 |
| Aucélio, RQ | 1 |
| Hardman, M | 1 |
| Makarov, AA | 1 |
| Dykes, S | 1 |
| Fancy, SA | 1 |
| Perkins, GL | 1 |
| Pullen, FS | 1 |
| BENAIM, S | 1 |
| Colombo, M | 1 |
| Sirtori, FR | 1 |
| Rizzo, V | 1 |
| Tang, K | 1 |
| Page, JS | 1 |
| Smith, RD | 1 |
| Herniman, JM | 1 |
| Bristow, TW | 1 |
| O'Connor, G | 1 |
| Jarvis, J | 1 |
| Langley, GJ | 1 |
| Tweats, DJ | 1 |
| Blakey, D | 1 |
| Heflich, RH | 1 |
| Jacobs, A | 1 |
| Jacobsen, SD | 1 |
| Morita, T | 1 |
| Nohmi, T | 1 |
| O'Donovan, MR | 1 |
| Sasaki, YF | 1 |
| Sofuni, T | 1 |
| Tice, R | 1 |
| Weaver, PJ | 1 |
| Laures, AM | 1 |
| Wolff, JC | 1 |
| Nemes, P | 1 |
| Vertes, A | 1 |
| Sen, AK | 1 |
| Nayak, R | 1 |
| Darabi, J | 1 |
| Knapp, DR | 1 |
| Mahnensmith, RL | 1 |
| Dertinger, SD | 1 |
| Torous, DK | 1 |
| Tometsko, AM | 1 |
| Shafi, S | 1 |
| Stepanova, IP | 1 |
| Fitzsimmons, C | 1 |
| Bowyer, DE | 1 |
| Welzel, D | 1 |
| Born, GV | 1 |
| Ke, J | 1 |
| Yancey, M | 1 |
| Zhang, S | 1 |
| Lowes, S | 1 |
| Henion, J | 1 |
| Collings, BA | 1 |
| Campbell, JM | 1 |
| Mao, D | 1 |
| Douglas, DJ | 1 |
1 review available for reserpine and Sensitivity and Specificity
| Article | Year |
|---|---|
Diabetic nephropathy: a comprehensive approach.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Clinical Protocols; Clinical Tria | 1993 |
19 other studies available for reserpine and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Liquid chromatography/tandem mass spectrometry method for the quantification of deserpidine in human plasma: Application to a pharmacokinetic study.
Topics: Chromatography, Liquid; Drug Stability; Humans; Linear Models; Reproducibility of Results; Reserpine | 2009 |
A miniature mass spectrometer for liquid chromatography applications.
Topics: Chromatography, High Pressure Liquid; Mass Spectrometry; Micro-Electrical-Mechanical Systems; Miniat | 2011 |
Surface-activated chemical ionization-electrospray ionization source improves biomarker discovery with mass spectrometry.
Topics: Adult; Analysis of Variance; Biomarkers, Tumor; Chromatography, Liquid; Humans; Ions; Male; Prostati | 2012 |
Room-temperature phosphorimetry for the selective determination of yohimbine in the presence of reserpine-like indolic alkaloids.
Topics: Chromatography, Paper; Hydrochloric Acid; Hydrogen-Ion Concentration; Luminescent Measurements; Rese | 2002 |
Interfacing the orbitrap mass analyzer to an electrospray ion source.
Topics: beta-Cyclodextrins; Cyclodextrins; Doxepin; Erythromycin; Mass Spectrometry; Raffinose; Reserpine; S | 2003 |
The automation of a commercial Fourier transform mass spectrometer to provide a quick and robust method for determining exact mass for the synthetic chemist.
Topics: Automation; Fourier Analysis; Ketoprofen; Mass Spectrometry; Molecular Weight; Reserpine; Sensitivit | 2003 |
The specificity of reserpine in the treatment of schizophrenia in identical twins. A controlled experiment.
Topics: Disease; Diseases in Twins; Reserpine; Schizophrenia; Sensitivity and Specificity; Twins; Twins, Mon | 1960 |
A fully automated method for accurate mass determination using high-performance liquid chromatography with a quadrupole/orthogonal acceleration time-of-flight mass spectrometer.
Topics: Automation; Chromatography, High Pressure Liquid; Mass Spectrometry; Reproducibility of Results; Res | 2004 |
Charge competition and the linear dynamic range of detection in electrospray ionization mass spectrometry.
Topics: Caffeine; Models, Chemical; Reserpine; Sensitivity and Specificity; Spectrometry, Mass, Electrospray | 2004 |
Improved precision and accuracy for high-performance liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometric exact mass measurement of small molecules from the simultaneous and controlled introduction of internal calibrants via
Topics: Calibration; Chromatography, High Pressure Liquid; Cyclotrons; Gramicidin; Mandelic Acids; Molecular | 2004 |
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards.
Topics: Aniline Compounds; Animals; Body Temperature; Bone Marrow Cells; Erythropoietin; Guidelines as Topic | 2007 |
Investigation of the advanced functionalities of a hybrid quadrupole orthogonal acceleration time-of-flight mass spectrometer.
Topics: Caffeine; Pharmaceutical Preparations; Reproducibility of Results; Reserpine; Sensitivity and Specif | 2007 |
Laser ablation electrospray ionization for atmospheric pressure, in vivo, and imaging mass spectrometry.
Topics: Atmospheric Pressure; Humans; Molecular Weight; Particle Size; Plant Leaves; Plant Roots; Plant Stem | 2007 |
Use of nanoporous alumina surface for desorption electrospray ionization mass spectrometry in proteomic analysis.
Topics: Aluminum Oxide; Animals; Cattle; Glass; Microscopy, Electron, Scanning; Particle Size; Polymers; Pol | 2008 |
In vitro system for detecting non-genotoxic carcinogens.
Topics: Animals; Anthracenes; Benzo(a)pyrene; Biological Assay; Butylated Hydroxyanisole; Butylated Hydroxyt | 1993 |
Effects of reserpine on expression of the LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo.
Topics: Animals; Arteriosclerosis; Culture Techniques; Disease Models, Animal; Ethinyl Estradiol; Fibrinogen | 2000 |
Quantitative liquid chromatographic-tandem mass spectrometric determination of reserpine in FVB/N mouse plasma using a "chelating" agent (disodium EDTA) for releasing protein-bound analytes during 96-well liquid-liquid extraction.
Topics: Animals; Blood Proteins; Chelating Agents; Chromatography, Liquid; Edetic Acid; Mass Spectrometry; M | 2000 |
A combined linear ion trap time-of-flight system with improved performance and MS(n) capabilities.
Topics: Angiotensinogen; Equipment Design; Mass Spectrometry; Reserpine; Sensitivity and Specificity | 2001 |