| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| methionine | [no description available] | medium | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid | antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
| glutaric acid | [no description available] | medium | 1 | 0 | alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid | Daphnia magna metabolite;
human metabolite |
| lysine | [no description available] | medium | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid | algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| resveratrol | [no description available] | medium | 1 | 0 | resveratrol | antioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger |
| methyl chloroformate | [no description available] | medium | 1 | 0 | | |
| lactic acid | [no description available] | medium | 1 | 0 | 2-hydroxy monocarboxylic acid | algal metabolite;
Daphnia magna metabolite |
| deuterium | [no description available] | medium | 2 | 1 | dihydrogen | |
| acetonitrile | [no description available] | medium | 1 | 0 | aliphatic nitrile;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent |
| trichloroethylene | [no description available] | medium | 1 | 0 | chloroethenes | inhalation anaesthetic;
mouse metabolite |
| guanidine | [no description available] | medium | 1 | 0 | carboxamidine;
guanidines;
one-carbon compound | |
| boric acid | [no description available] | medium | 1 | 0 | boric acids | astringent |
| glycine | [no description available] | medium | 1 | 0 | alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical |
| methylguanidine | [no description available] | medium | 1 | 0 | guanidines | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite;
uremic toxin |
| butyric acid | [no description available] | medium | 1 | 0 | fatty acid 4:0;
straight-chain saturated fatty acid | human urinary metabolite;
Mycoplasma genitalium metabolite |
| arginine | [no description available] | medium | 2 | 0 | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
| guanidinosuccinic acid | [no description available] | medium | 1 | 0 | L-alpha-amino acid anion | |
| guanidinopropionic acid | [no description available] | medium | 1 | 0 | guanidines;
zwitterion | hypoglycemic agent |
| acetone | [no description available] | medium | 1 | 0 | ketone body;
methyl ketone;
propanones;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent |
| glycocyamine | [no description available] | medium | 1 | 0 | guanidinoacetic acids;
zwitterion | bacterial metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite |
| isoleucine | [no description available] | medium | 2 | 0 | aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| linoleic acid | [no description available] | medium | 1 | 0 | octadecadienoic acid;
omega-6 fatty acid | algal metabolite;
Daphnia galeata metabolite;
plant metabolite |
| leucine | [no description available] | medium | 2 | 0 | amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| myristic acid | [no description available] | medium | 1 | 0 | long-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite |
| valine | [no description available] | medium | 1 | 0 | L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
| hydrazine | [no description available] | medium | 1 | 0 | azane;
hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor |
| isoniazid | [no description available] | medium | 1 | 0 | carbohydrazide | antitubercular agent;
drug allergen |
| trifluoroacetic acid | [no description available] | medium | 1 | 0 | fluoroalkanoic acid | human xenobiotic metabolite;
NMR chemical shift reference compound;
reagent |
| spermine | [no description available] | medium | 2 | 0 | polyazaalkane;
tetramine | antioxidant;
fundamental metabolite;
immunosuppressive agent |
| spermidine | [no description available] | medium | 3 | 0 | polyazaalkane;
triamine | autophagy inducer;
fundamental metabolite;
geroprotector |
| putrescine | [no description available] | medium | 3 | 0 | alkane-alpha,omega-diamine | antioxidant;
fundamental metabolite |
| bisphenol a | [no description available] | medium | 1 | 0 | bisphenol | endocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen |
| pregabalin | [no description available] | medium | 1 | 0 | gamma-amino acid | anticonvulsant;
calcium channel blocker |
| gamma-aminobutyric acid | [no description available] | medium | 1 | 0 | amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid | human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule |
| sodium sulfate | [no description available] | medium | 1 | 0 | inorganic sodium salt | |
| sorbic acid | [no description available] | medium | 1 | 0 | alpha,beta-unsaturated monocarboxylic acid;
sorbic acid | |
| muconic acid | [no description available] | medium | 1 | 0 | muconic acid | biomarker;
human xenobiotic metabolite |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | [no description available] | medium | 1 | 0 | methylpyridines;
phenylpyridine;
tetrahydropyridine | neurotoxin |
| 3,4-dihydroxyphenylacetic acid | [no description available] | medium | 1 | 0 | catechols;
dihydroxyphenylacetic acid | human metabolite |
| 3-methoxytyramine | [no description available] | medium | 1 | 0 | monomethoxybenzene;
phenols;
phenylethylamine;
primary amino compound | biomarker;
human blood serum metabolite;
human urinary metabolite |
| homovanillic acid | [no description available] | medium | 1 | 0 | guaiacols;
monocarboxylic acid | human metabolite;
mouse metabolite |
| glyoxal | [no description available] | medium | 1 | 0 | dialdehyde | agrochemical;
allergen;
pesticide;
plant growth regulator |
| fenclonine | [no description available] | medium | 1 | 0 | phenylalanine derivative | |
| sodium hydroxide | [no description available] | medium | 1 | 0 | alkali metal hydroxide | |
| pyridine | [no description available] | medium | 1 | 0 | azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines | environmental contaminant;
NMR chemical shift reference compound |
| tyramine | [no description available] | medium | 1 | 0 | monoamine molecular messenger;
primary amino compound;
tyramines | EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter |
| phenyl acetate | [no description available] | medium | 2 | 0 | benzenes;
phenyl acetates | |
| allyl chloroformate | [no description available] | medium | 1 | 0 | | |
| acetyl chloride | [no description available] | medium | 1 | 0 | acyl chloride | |
| trichloroacetonitrile | [no description available] | medium | 1 | 0 | aliphatic nitrile;
organochlorine compound | |
| chlorine | [no description available] | medium | 1 | 0 | halide anion;
monoatomic chlorine | cofactor;
Escherichia coli metabolite;
human metabolite |
| beta-n-methylamino-l-alanine | [no description available] | medium | 1 | 0 | diamino acid;
L-alanine derivative;
non-proteinogenic L-alpha-amino acid;
secondary amino compound | bacterial metabolite;
neurotoxin |
| fluoxetine | [no description available] | medium | 1 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound | |
| desipramine | [no description available] | medium | 1 | 0 | dibenzoazepine;
secondary amino compound | adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor |
| glutaral | [no description available] | medium | 1 | 0 | dialdehyde | cross-linking reagent;
disinfectant;
fixative |
| chlorine | [no description available] | medium | 2 | 0 | diatomic chlorine;
gas molecular entity | bleaching agent |
| n(1)-acetylspermidine | [no description available] | medium | 1 | 0 | acetylspermidine | Escherichia coli metabolite;
metabolite |
| n-acetylputrescine | [no description available] | medium | 1 | 0 | N-monoacetylalkane-alpha,omega-diamine;
N-substituted putrescine | metabolite;
mouse metabolite |
| cadaverine | [no description available] | medium | 1 | 0 | alkane-alpha,omega-diamine | Daphnia magna metabolite;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite |
| n(8)-acetylspermidine | [no description available] | medium | 1 | 0 | acetylspermidine | Escherichia coli metabolite;
human metabolite |
| monoacetylcadaverine | [no description available] | medium | 1 | 0 | acetamides;
N-substituted cadaverine;
primary amino compound;
secondary carboxamide | human metabolite |
| tyrosine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine | EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical |
| asparagine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| glutamine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
| 8-aminoquinoline | [no description available] | medium | 1 | 0 | | |
| primaquine | [no description available] | medium | 1 | 0 | aminoquinoline;
aromatic ether;
N-substituted diamine | antimalarial |
| ibuprofen | [no description available] | medium | 2 | 0 | monocarboxylic acid | antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic |
| eedq | [no description available] | medium | 1 | 0 | | |
| trifluoroethanol | [no description available] | medium | 1 | 1 | fluoroalcohol | |
| cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine | [no description available] | medium | 1 | 0 | | |
| cidofovir anhydrous | [no description available] | medium | 1 | 0 | phosphonic acids;
pyrimidone | anti-HIV agent;
antineoplastic agent;
antiviral drug;
photosensitizing agent |
| cytosine | [no description available] | medium | 1 | 0 | aminopyrimidine;
pyrimidine nucleobase;
pyrimidone | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| organophosphonates | [no description available] | medium | 1 | 0 | divalent inorganic anion;
phosphite ion | |
| 1-(1-naphthyl)ethylamine | [no description available] | medium | 1 | 0 | | |
| 1-butanol | [no description available] | medium | 1 | 0 | alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol | human metabolite;
mouse metabolite;
protic solvent |
| propylene oxide | [no description available] | medium | 1 | 0 | epoxide | |
| propiolactone | [no description available] | medium | 1 | 0 | propan-3-olide | |
| methyl methanesulfonate | [no description available] | medium | 1 | 0 | methanesulfonate ester | alkylating agent;
apoptosis inducer;
carcinogenic agent;
genotoxin;
mutagen |
| 2,2-dichloroacetyl chloride | [no description available] | medium | 1 | 0 | acyl chloride | hapten |
| indoprofen | [no description available] | medium | 1 | 0 | gamma-lactam;
isoindoles;
monocarboxylic acid | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |