Proteins > Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
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Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
A xanthine dehydrogenase/oxidase that is encoded in the genome of rat. [OMA:P22985, PRO:DNx]
Synonyms
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| febuxostat | Rattus norvegicus (Norway rat) | IC50 | 0.0040 | 1 | 1 |
| silybin | Rattus norvegicus (Norway rat) | IC50 | 80.3000 | 1 | 1 |
| 2,3-dehydrosilybin | Rattus norvegicus (Norway rat) | IC50 | 80.3000 | 1 | 1 |
| allopurinol | Rattus norvegicus (Norway rat) | IC50 | 9.3177 | 3 | 3 |
Trisubstituted thiophene analogues of 1-thiazolyl-2-pyrazoline, super oxidase inhibitors and free radical scavengers.Bioorganic & medicinal chemistry, , Jan-01, Volume: 21, Issue:1, 2013
Synthesis and xanthine oxidase inhibitory activity of 7-methyl-2-(phenoxymethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one derivatives.Bioorganic & medicinal chemistry, , Jan-01, Volume: 19, Issue:1, 2011
Design, synthesis, and examination of neuron protective properties of alkenylated and amidated dehydro-silybin derivatives.Journal of medicinal chemistry, , Dec-10, Volume: 52, Issue:23, 2009