Page last updated: 2024-08-07 23:57:54
Transporter
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Synonyms
Research
Bioassay Publications (11)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (17)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| fluoxetine | Rattus norvegicus (Norway rat) | Ki | 2.0000 | 1 | 1 |
| haloperidol | Rattus norvegicus (Norway rat) | Ki | 5.5000 | 1 | 1 |
| modafinil | Rattus norvegicus (Norway rat) | IC50 | 63.9000 | 2 | 2 |
| nisoxetine | Rattus norvegicus (Norway rat) | Ki | 0.0060 | 1 | 1 |
| nomifensine | Rattus norvegicus (Norway rat) | Ki | 0.0120 | 2 | 2 |
| quetiapine | Rattus norvegicus (Norway rat) | Ki | 0.6800 | 1 | 1 |
| risperidone | Rattus norvegicus (Norway rat) | Ki | 28.0000 | 1 | 1 |
| venlafaxine | Rattus norvegicus (Norway rat) | IC50 | 0.6400 | 1 | 1 |
| atomoxetine | Rattus norvegicus (Norway rat) | Ki | 0.0040 | 1 | 1 |
| duloxetine | Rattus norvegicus (Norway rat) | Ki | 0.0100 | 2 | 2 |
| ziprasidone | Rattus norvegicus (Norway rat) | Ki | 0.0480 | 1 | 1 |
| bifeprunox | Rattus norvegicus (Norway rat) | Ki | 0.0093 | 1 | 1 |
| calcitriol | Rattus norvegicus (Norway rat) | Ki | 0.0001 | 1 | 1 |
| daidzein | Rattus norvegicus (Norway rat) | IC50 | 0.4500 | 1 | 1 |
| milnacipran | Rattus norvegicus (Norway rat) | IC50 | 0.0650 | 2 | 2 |
| clozapine | Rattus norvegicus (Norway rat) | Ki | 0.3900 | 1 | 1 |
| olanzapine | Rattus norvegicus (Norway rat) | Ki | 2.0000 | 1 | 1 |
Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and antidepressant activity.ACS medicinal chemistry letters, , Jan-10, Volume: 4, Issue:1, 2013
4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.Bioorganic & medicinal chemistry letters, , Dec-01, Volume: 22, Issue:23, 2012
4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.Bioorganic & medicinal chemistry letters, , Dec-01, Volume: 22, Issue:23, 2012
1-Naphthyl and 4-indolyl arylalkylamines as selective monoamine reuptake inhibitors.Bioorganic & medicinal chemistry letters, , Jan-01, Volume: 19, Issue:1, 2009
13,13-Dimethyl-des-C,D analogues of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D₃ (2MD): total synthesis, docking to the VDR, and biological evaluation.Bioorganic & medicinal chemistry, , Dec-01, Volume: 19, Issue:23, 2011