| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| pyrethrins | [no description available] | medium | 757 | 20 | | |
| decamethrin | [no description available] | high | 94 | 0 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound | agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide |
| decamethrin | [no description available] | high | 94 | 1 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound | agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide |
| methoxsalen | [no description available] | medium | 1 | 0 | aromatic ether;
psoralens | antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite |
| ecdysterone | [no description available] | medium | 1 | 0 | 14alpha-hydroxy steroid;
20-hydroxy steroid;
22-hydroxy steroid;
25-hydroxy steroid;
2beta-hydroxy steroid;
3beta-sterol;
ecdysteroid;
phytoecdysteroid | animal metabolite;
plant metabolite |
| permethrin | [no description available] | high | 64 | 0 | cyclopropanecarboxylate ester;
cyclopropanes | agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide |
| permethrin | [no description available] | high | 64 | 5 | cyclopropanecarboxylate ester;
cyclopropanes | agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide |
| chlorpyrifos-methyl | [no description available] | medium | 3 | 0 | chloropyridine;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic |
| chlorpyrifos | [no description available] | medium | 59 | 0 | chloropyridine;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic |
| tebuconazole | [no description available] | medium | 4 | 0 | monochlorobenzenes;
tertiary alcohol;
triazoles | |
| triazoles | [no description available] | medium | 10 | 0 | 1,2,3-triazole | |
| captan | [no description available] | medium | 5 | 0 | isoindoles;
organochlorine compound;
organosulfur compound;
phthalimide fungicide | antifungal agrochemical |
| rutin | [no description available] | medium | 1 | 0 | disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone | antioxidant;
metabolite |
| betadex | [no description available] | medium | 1 | 0 | cyclodextrin | |
| carbendazim | [no description available] | medium | 4 | 0 | benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester | antifungal agrochemical;
antinematodal drug;
metabolite;
microtubule-destabilising agent |
| bifenthrin | [no description available] | high | 44 | 0 | carboxylic ester;
cyclopropanecarboxylate ester;
cyclopropanes;
organochlorine compound;
organofluorine compound | pyrethroid ester acaricide;
pyrethroid ester insecticide |
| imidacloprid | [no description available] | medium | 37 | 0 | imidacloprid;
imidazolidines;
monochloropyridine | environmental contaminant;
genotoxin;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic |
| taurine | [no description available] | medium | 2 | 0 | amino sulfonic acid;
zwitterion | antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite |
| methomyl | [no description available] | medium | 6 | 0 | aliphatic sulfide;
carbamate ester | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
nematicide;
xenobiotic |
| phoxim | [no description available] | medium | 11 | 0 | | |
| sodium taurodeoxycholate | [no description available] | medium | 1 | 0 | bile acid taurine conjugate | human metabolite |
| azoxystrobin | [no description available] | medium | 4 | 0 | aryloxypyrimidine;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
methyl ester;
nitrile | antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
quinone outside inhibitor;
xenobiotic |
| acephate | [no description available] | medium | 2 | 0 | mixed diacylamine;
organic thiophosphate;
organothiophosphate insecticide;
phosphoramide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| dimethoate | [no description available] | medium | 11 | 0 | monocarboxylic acid amide;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic |
| tryptophan | [no description available] | medium | 1 | 0 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan | antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| cypermethrin | [no description available] | high | 85 | 0 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound | agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| cypermethrin | [no description available] | high | 85 | 2 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound | agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| kresoxim-methyl | [no description available] | medium | 2 | 0 | aromatic ether;
methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
oxime O-ether | antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic |
| 3-phenoxybenzoic acid | [no description available] | medium | 15 | 0 | phenoxybenzoic acid | human xenobiotic metabolite;
marine xenobiotic metabolite |
| emamectin benzoate | [no description available] | medium | 6 | 0 | emamectins | |
| thiamethoxam | [no description available] | medium | 16 | 0 | 1,3-thiazoles;
2-nitroguanidine derivative;
organochlorine compound;
oxadiazane | antifeedant;
carcinogenic agent;
environmental contaminant;
neonicotinoid insectide;
xenobiotic |
| chlorantranilipole | [no description available] | medium | 10 | 0 | monochlorobenzenes;
organobromine compound;
pyrazole insecticide;
pyrazoles;
pyridines;
secondary carboxamide | ryanodine receptor agonist |
| temefos | [no description available] | medium | 6 | 0 | organic sulfide;
organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
ectoparasiticide |
| vitamin k semiquinone radical | [no description available] | medium | 1 | 0 | | |
| retinol | [no description available] | medium | 1 | 0 | retinol;
vitamin A | human metabolite;
mouse metabolite;
plant metabolite |
| tetramethrin | [no description available] | high | 2 | 0 | cyclopropanecarboxylate ester;
maleimides;
phthalimide insecticide | pyrethroid ester insecticide |
| gold | [no description available] | medium | 1 | 0 | copper group element atom;
elemental gold | |
| carvacrol | [no description available] | medium | 1 | 0 | botanical anti-fungal agent;
p-menthane monoterpenoid;
phenols | agrochemical;
antimicrobial agent;
flavouring agent;
TRPA1 channel agonist;
volatile oil component |
| propoxur | [no description available] | high | 11 | 0 | aromatic ether;
carbamate ester | acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| malathion | [no description available] | medium | 28 | 0 | diester;
ethyl ester;
organic thiophosphate | |
| thiophanate | [no description available] | medium | 2 | 0 | benzimidazole precursor fungicide;
carbamate ester;
carbamate fungicide;
thioureas | antifungal drug |
| nabam | [no description available] | medium | 1 | 0 | dithiocarbamic acids | |
| atrazine | [no description available] | medium | 11 | 0 | chloro-1,3,5-triazine;
diamino-1,3,5-triazine | environmental contaminant;
herbicide;
xenobiotic |
| copper sulfate | [no description available] | medium | 1 | 0 | metal sulfate | emetic;
fertilizer;
sensitiser |
| astaxanthine | [no description available] | medium | 1 | 0 | carotenol;
carotenone | animal metabolite;
anticoagulant;
antioxidant;
food colouring;
plant metabolite |
| prizes | [no description available] | medium | 11 | 0 | carboxamidine;
monochloropyridine;
nitrile | environmental contaminant;
neonicotinoid insectide;
xenobiotic |
| bendiocarb | [no description available] | medium | 9 | 0 | benzodioxoles;
carbamate ester | agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| ddt | [no description available] | medium | 38 | 0 | benzenoid aromatic compound;
chlorophenylethane;
monochlorobenzenes;
organochlorine insecticide | bridged diphenyl acaricide;
carcinogenic agent;
endocrine disruptor;
persistent organic pollutant |
| novaluron | [no description available] | medium | 2 | 0 | aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound | |
| thiacloprid | [no description available] | medium | 4 | 0 | monochloropyridine;
nitrile;
thiazolidines | environmental contaminant;
neonicotinoid insectide;
xenobiotic |
| cyantraniliprole | [no description available] | medium | 1 | 0 | nitrile;
organobromine compound;
organochlorine compound;
pyrazole insecticide;
pyridines;
secondary carboxamide | ryanodine receptor agonist |
| cyfluthrin | [no description available] | high | 23 | 0 | aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound | agrochemical;
pyrethroid ester insecticide |
| cyphenothrin | [no description available] | high | 2 | 0 | cyclopropanecarboxylate ester | agrochemical;
pyrethroid ester insecticide |
| fenvalerate | [no description available] | high | 27 | 0 | aromatic ether;
carboxylic ester;
monochlorobenzenes | pyrethroid ester acaricide;
pyrethroid ester insecticide |
| triazophos | [no description available] | medium | 1 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide |
| fipronil | [no description available] | medium | 10 | 0 | (trifluoromethyl)benzenes;
dichlorobenzene;
nitrile;
primary amino compound;
pyrazoles;
sulfoxide | |
| curcumin | [no description available] | medium | 1 | 0 | aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol | anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger |
| tetraconazole | [no description available] | medium | 2 | 0 | dichlorobenzene;
ether;
organofluorine compound;
triazoles | |
| mannuronic acid | [no description available] | medium | 1 | 0 | D-mannonic acid | |
| mefenoxam | [no description available] | medium | 1 | 0 | acylamino acid fungicide;
anilide fungicide;
D-alanine derivative;
methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate | agrochemical |
| alanine | [no description available] | medium | 2 | 0 | alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid | EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite |
| metalaxyl | [no description available] | medium | 2 | 0 | alanine derivative;
aromatic amide;
carboxamide;
ether;
methyl ester | |
| cycloxaprid | [no description available] | medium | 1 | 0 | | |
| oxadiargyl | [no description available] | medium | 1 | 0 | | |
| prothiophos | [no description available] | medium | 1 | 0 | dichlorobenzene;
organic thiophosphate;
organosulfur compound | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide |
| oxadiazoles | [no description available] | medium | 1 | 0 | | |
| naringenin | [no description available] | medium | 1 | 0 | (2S)-flavan-4-one;
naringenin | expectorant;
plant metabolite |
| oxyfluorofen | [no description available] | medium | 1 | 0 | aromatic ether | EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| fenpropathrin, (+-)-isomer | [no description available] | high | 11 | 0 | aromatic ether;
cyclopropanecarboxylate ester | agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| azadirachtin | [no description available] | medium | 4 | 0 | acetate ester;
azadirachtin;
cyclic hemiketal;
enoate ester;
epoxide;
methyl ester;
organic heterotetracyclic compound;
secondary alcohol;
tertiary alcohol | hepatoprotective agent |
| profenofos | [no description available] | medium | 3 | 0 | monochlorobenzenes;
organic thiophosphate;
organochlorine insecticide;
organophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| pyrachlostrobin | [no description available] | medium | 2 | 0 | aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles | antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic |
| chlorfenapyr | [no description available] | medium | 3 | 0 | hemiaminal ether;
monochlorobenzenes;
nitrile;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide;
pyrroles | proacaricide;
proinsecticide |
| clothianidin | [no description available] | medium | 3 | 0 | 1,3-thiazoles;
2-nitroguanidine derivative;
clothianidin;
organochlorine compound | environmental contaminant;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic |
| sulfur | [no description available] | medium | 2 | 0 | chalcogen;
nonmetal atom | macronutrient |
| thiazoles | [no description available] | medium | 12 | 0 | 1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
| sulfoxaflor | [no description available] | medium | 2 | 0 | nitrile;
organofluorine compound;
pyridines;
sulfoximide | |
| penthiopyrad | [no description available] | medium | 1 | 0 | aromatic amide;
organofluorine compound;
pyrazoles;
thiophenes | |
| thiophenes | [no description available] | medium | 3 | 0 | mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound | non-polar solvent |
| phosmet | [no description available] | medium | 2 | 0 | organic thiophosphate;
organothiophosphate insecticide;
phthalimides | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| chrysanthemic acid | [no description available] | medium | 1 | 0 | cyclopropanes;
monocarboxylic acid | plant metabolite |
| leucine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| fluphenacur | [no description available] | medium | 2 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organofluorine compound | |
| ethofenprox | [no description available] | medium | 5 | 0 | aromatic ether | pyrethroid ether insecticide |
| dieldrin | [no description available] | medium | 5 | 0 | epoxide;
organochlorine compound;
organochlorine insecticide | carcinogenic agent;
xenobiotic |
| endosulfan | [no description available] | medium | 12 | 0 | cyclic sulfite ester;
cyclodiene organochlorine insecticide | acaricide;
agrochemical;
GABA-gated chloride channel antagonist;
persistent organic pollutant |
| 2-cyano-n-((ethylamino)carbonyl)-2-(methoxyimino)acetamide | [no description available] | medium | 1 | 0 | | |
| dizocilpine maleate | [no description available] | medium | 1 | 0 | maleate salt;
tetracyclic antidepressant | anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist |
| carbamates | [no description available] | medium | 12 | 0 | amino-acid anion | |
| triiodothyronine | [no description available] | medium | 1 | 0 | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine | human metabolite;
mouse metabolite;
thyroid hormone |
| quercetin | [no description available] | medium | 3 | 0 | 7-hydroxyflavonol;
pentahydroxyflavone | antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger |
| thyroxine | [no description available] | medium | 1 | 0 | 2-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine | antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone |
| phenyl acetate | [no description available] | medium | 1 | 0 | benzenes;
phenyl acetates | |
| trifloxystrobin | [no description available] | medium | 1 | 0 | | |
| dextrothyroxine | [no description available] | medium | 11 | 0 | | |
| pyriproxyfen | [no description available] | medium | 7 | 0 | aromatic ether;
pyridines | juvenile hormone mimic |
| pyriproxyfen | [no description available] | medium | 7 | 1 | aromatic ether;
pyridines | juvenile hormone mimic |
| spiromesifen | [no description available] | medium | 1 | 0 | butenolide | insecticide |
| spinetoram | [no description available] | medium | 2 | 0 | organic molecular entity | |
| acid phosphatase | [no description available] | medium | 1 | 0 | | |
| dichlorvos | [no description available] | medium | 4 | 0 | alkenyl phosphate;
dialkyl phosphate;
organochlorine acaricide;
organophosphate insecticide | anthelminthic drug;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| 2,4-d amine | [no description available] | medium | 1 | 0 | | |
| haloxyfop | [no description available] | medium | 1 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines | |
| glycine | [no description available] | medium | 4 | 0 | alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical |
| 2,4-dichlorophenoxyacetic acid | [no description available] | medium | 1 | 0 | chlorophenoxyacetic acid;
dichlorobenzene | agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin |
| phosphine | [no description available] | medium | 1 | 0 | mononuclear parent hydride;
phosphanes;
phosphine | carcinogenic agent;
fumigant insecticide |
| ethylene glycol | [no description available] | medium | 1 | 0 | ethanediol;
glycol | metabolite;
mouse metabolite;
solvent;
toxin |
| indoxacarb | [no description available] | medium | 6 | 0 | methyl ester;
organochlorine insecticide | voltage-gated sodium channel blocker |
| 1-aminobenzotriazole | [no description available] | medium | 1 | 0 | | |
| methidathion | [no description available] | medium | 1 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| tebufenozide | [no description available] | medium | 2 | 0 | carbohydrazide | ecdysone agonist;
environmental contaminant;
xenobiotic |
| hydrazine | [no description available] | medium | 2 | 0 | azane;
hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor |
| diazinon | [no description available] | medium | 10 | 0 | organic thiophosphate;
pyrimidines | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
nematicide;
xenobiotic |
| diazinon | [no description available] | medium | 10 | 2 | organic thiophosphate;
pyrimidines | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
nematicide;
xenobiotic |
| teflubenzuron | [no description available] | medium | 1 | 0 | dichlorobenzene;
difluorobenzene;
N-acylurea | environmental contaminant;
insecticide;
xenobiotic |
| d-alpha tocopherol | [no description available] | medium | 3 | 0 | alpha-tocopherol | algal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite |
| zinc oxide | [no description available] | medium | 1 | 0 | zinc molecular entity | |
| amitraz | [no description available] | medium | 1 | 0 | formamidines;
tertiary amino compound | acaricide;
environmental contaminant;
insecticide;
xenobiotic |
| malondialdehyde | [no description available] | medium | 6 | 0 | dialdehyde | biomarker |
| ethacrynic acid | [no description available] | medium | 1 | 0 | aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid | EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic |
| triphenyl phosphate | [no description available] | medium | 2 | 0 | aryl phosphate | flame retardant;
plasticiser |
| pirimiphos methyl | [no description available] | medium | 3 | 0 | aminopyrimidine;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide |
| piperonyl butoxide | [no description available] | medium | 9 | 1 | benzodioxoles | pesticide synergist |
| pyrroles | [no description available] | medium | 1 | 0 | pyrrole;
secondary amine | |
| sodium dodecyl sulfate | [no description available] | medium | 1 | 0 | organic sodium salt | detergent;
protein denaturant |
| ascorbic acid | [no description available] | medium | 5 | 0 | ascorbic acid;
vitamin C | coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent |
| 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile | [no description available] | medium | 1 | 0 | monochlorobenzenes;
nitrile;
triazoles | |
| 8,10-dodecadien-1-ol | [no description available] | medium | 1 | 0 | | |
| dodecanol | [no description available] | medium | 1 | 0 | dodecanol;
primary alcohol | bacterial metabolite;
cosmetic;
insect attractant;
insecticide;
pheromone;
plant metabolite |
| ferric citrate | [no description available] | medium | 1 | 0 | iron chelate | anti-anaemic agent;
nutraceutical |
| fenitrothion | [no description available] | medium | 9 | 0 | C-nitro compound;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide |
| fenitrothion | [no description available] | medium | 9 | 1 | C-nitro compound;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide |
| europium | [no description available] | medium | 1 | 0 | f-block element atom;
lanthanoid atom | |
| dimethoxon | [no description available] | medium | 1 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| triflumuron | [no description available] | medium | 1 | 0 | aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound | |
| butachlor | [no description available] | medium | 5 | 0 | aromatic amide;
organochlorine compound;
tertiary carboxamide | environmental contaminant;
herbicide;
xenobiotic |
| hexaconazole | [no description available] | medium | 1 | 0 | dichlorobenzene;
tertiary alcohol;
triazoles | chelator |
| methane | [no description available] | medium | 2 | 0 | alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound | bacterial metabolite;
fossil fuel;
greenhouse gas |
| piperidines | [no description available] | medium | 1 | 0 | | |
| picaridin | [no description available] | medium | 1 | 0 | carboxylic acid;
piperidines | |
| deet | [no description available] | medium | 2 | 0 | benzamides;
monocarboxylic acid amide | environmental contaminant;
insect repellent;
xenobiotic |
| ethyl-3-(n-n-butyl-n-acetyl)aminopropionate | [no description available] | medium | 1 | 0 | acetamides;
ethyl ester;
tertiary carboxamide | |
| cadmium | [no description available] | medium | 7 | 0 | cadmium molecular entity;
zinc group element atom | |
| avermectin | [no description available] | medium | 3 | 0 | | |
| flumethrin | [no description available] | medium | 2 | 0 | | |
| carbaryl | [no description available] | medium | 3 | 0 | carbamate ester;
naphthalenes | acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant growth retardant |
| methyl parathion | [no description available] | medium | 4 | 0 | C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
genotoxin |
| hexafluoron | [no description available] | medium | 1 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organochlorine insecticide;
organofluorine insecticide | |
| medigoxin | [no description available] | medium | 1 | 0 | | |
| quintozene | [no description available] | medium | 1 | 0 | aromatic fungicide;
C-nitro compound;
pentachlorobenzenes | antifungal agrochemical |
| spermidine | [no description available] | medium | 1 | 0 | polyazaalkane;
triamine | autophagy inducer;
fundamental metabolite;
geroprotector |
| ubiquinone | [no description available] | medium | 1 | 0 | | |
| ubiquinone q2 | [no description available] | medium | 1 | 0 | ubiquinones | |
| pheophytin a | [no description available] | medium | 1 | 0 | | |
| chlorophyll a | [no description available] | medium | 1 | 0 | chlorophyll;
methyl ester | cofactor |
| bio 1211 | [no description available] | medium | 1 | 0 | | |
| thymoquinone | [no description available] | medium | 1 | 0 | 1,4-benzoquinones | adjuvant;
anti-inflammatory agent;
antidepressant;
antineoplastic agent;
antioxidant;
cardioprotective agent;
plant metabolite |
| letrozole | [no description available] | medium | 1 | 0 | nitrile;
triazoles | antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor |
| nitrites | [no description available] | medium | 1 | 0 | monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species | human metabolite |
| menthol | [no description available] | medium | 1 | 0 | p-menthane monoterpenoid;
secondary alcohol | volatile oil component |
| terpin | [no description available] | medium | 1 | 0 | p-menthane monoterpenoid | |
| dicrotophos | [no description available] | medium | 1 | 0 | dialkyl phosphate;
organophosphate insecticide | acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| corticosterone | [no description available] | medium | 3 | 0 | 11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite |
| heptachlor | [no description available] | medium | 1 | 0 | cyclodiene organochlorine insecticide | agrochemical;
antibacterial agent;
antifungal agent;
GABA-gated chloride channel antagonist;
persistent organic pollutant |
| dibutylaminosulfenylcarbofuran | [no description available] | medium | 1 | 0 | 1-benzofurans;
carbamate ester | acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide |
| flubendiamide | [no description available] | medium | 1 | 0 | organofluorine insecticide | ryanodine receptor modulator |
| tetrachloroisophthalonitrile | [no description available] | medium | 2 | 0 | aromatic fungicide;
dinitrile;
tetrachlorobenzene | antifungal agrochemical |
| azomethane | [no description available] | medium | 1 | 0 | | |
| procymidone | [no description available] | medium | 2 | 0 | | |
| thiabendazole | [no description available] | medium | 1 | 0 | 1,3-thiazoles;
benzimidazole fungicide;
benzimidazoles | antifungal agrochemical;
antinematodal drug |
| 4-nitrophenyl acetate | [no description available] | medium | 1 | 0 | C-nitro compound;
phenyl acetates | |
| nitrophenols | [no description available] | medium | 1 | 0 | | |
| azinphosmethyl | [no description available] | medium | 2 | 0 | benzotriazines;
organic thiophosphate;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| cellulose | [no description available] | medium | 1 | 0 | glycoside | |
| buprofezin | [no description available] | medium | 1 | 0 | thiadiazinane;
ureas | |
| metolachlor | [no description available] | medium | 2 | 0 | aromatic amide;
benzenes;
ether;
organochlorine compound | |
| niacinamide | [no description available] | medium | 1 | 0 | pyridine alkaloid;
pyridinecarboxamide;
vitamin B3 | anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor |
| nitrogen dioxide | [no description available] | medium | 1 | 0 | nitrogen oxide | |
| urea | [no description available] | medium | 1 | 0 | isourea;
monocarboxylic acid amide;
one-carbon compound | Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| 1,4-dioxane | [no description available] | medium | 1 | 0 | dioxane;
volatile organic compound | carcinogenic agent;
metabolite;
NMR chemical shift reference compound;
non-polar solvent |
| butyl phosphorotrithioate | [no description available] | medium | 2 | 0 | organic thiophosphate | defoliant |
| caffeic acid phenethyl ester | [no description available] | medium | 1 | 0 | alkyl caffeate ester | anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent |
| phenylethyl alcohol | [no description available] | medium | 1 | 0 | benzenes;
primary alcohol | Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| caffeic acid | [no description available] | medium | 1 | 0 | caffeic acid | geroprotector;
mouse metabolite |
| dicofol | [no description available] | medium | 1 | 0 | monochlorobenzenes;
organochlorine acaricide;
tertiary alcohol | |
| ammonium hydroxide | [no description available] | medium | 1 | 0 | azane;
gas molecular entity;
mononuclear parent hydride | EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant |
| resmethrin | [no description available] | high | 2 | 0 | cyclopropanecarboxylate ester;
furans | agrochemical;
pyrethroid ester insecticide |
| tralomethrin | [no description available] | medium | 1 | 0 | | |
| fluvalinate | [no description available] | high | 5 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
nitrile;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide | agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide |
| methamidophos | [no description available] | medium | 1 | 0 | organic thiophosphate;
organothiophosphate insecticide;
phosphoramide | acaricide;
agrochemical;
avicide |
| sodium bromide | [no description available] | medium | 1 | 0 | bromide salt;
inorganic sodium salt | |
| fenoxycarb | [no description available] | medium | 1 | 0 | aromatic ether;
carbamate ester | environmental contaminant;
insecticide;
juvenile hormone mimic;
xenobiotic |
| 3,4-dichloroaniline | [no description available] | medium | 2 | 0 | dichloroaniline | epitope;
xenobiotic |
| bromide | [no description available] | medium | 1 | 0 | halide anion;
monoatomic bromine | |
| pirimicarb | [no description available] | medium | 2 | 0 | aminopyrimidine;
carbamate ester;
tertiary amino compound | agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic |
| fenton's reagent | [no description available] | medium | 1 | 0 | | |
| fluazifop-butyl | [no description available] | medium | 1 | 0 | aromatic ether;
carboxylic ester;
organofluorine compound;
pyridines | |
| acetone | [no description available] | medium | 2 | 0 | ketone body;
methyl ketone;
propanones;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent |
| picrotoxin | [no description available] | medium | 1 | 0 | | |
| mitomycin | [no description available] | medium | 2 | 0 | mitomycin | alkylating agent;
antineoplastic agent |
| choline | [no description available] | medium | 2 | 0 | cholines | allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| allethrins | [no description available] | high | 3 | 0 | cyclopropanecarboxylate ester | pyrethroid ester insecticide |
| thifensulfuron methyl | [no description available] | medium | 1 | 0 | 1,3,5-triazines;
methyl ester;
N-sulfonylurea;
thiophenes | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| thidiazuron | [no description available] | medium | 1 | 0 | ureas | |
| hydroxyindoleacetic acid | [no description available] | medium | 1 | 0 | indole-3-acetic acids | drug metabolite;
human metabolite;
mouse metabolite |
| benzyl benzoate | [no description available] | medium | 1 | 0 | benzoate ester;
benzyl ester | acaricide;
plant metabolite;
scabicide |
| trypan blue | [no description available] | medium | 1 | 0 | | |
| dorzolamide | [no description available] | medium | 1 | 0 | sulfonamide;
thiophenes | antiglaucoma drug;
antihypertensive agent;
EC 4.2.1.1 (carbonic anhydrase) inhibitor |
| brinzolamide | [no description available] | medium | 1 | 0 | sulfonamide;
thienothiazine | antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor |
| heptenophos | [no description available] | high | 1 | 0 | organochlorine compound;
organophosphate insecticide;
trialkyl phosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| pymetrozine | [no description available] | medium | 1 | 0 | 1,2,4-triazines;
pyridines | antifeedant;
environmental contaminant;
TRPV channel modulator;
xenobiotic |
| tetrodotoxin | [no description available] | medium | 1 | 0 | azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid | animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker |
| nimodipine | [no description available] | medium | 1 | 0 | 2-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester | antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent |
| benomyl | [no description available] | medium | 1 | 0 | aromatic amide;
benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester | acaricide;
anthelminthic drug;
antifungal agrochemical;
microtubule-destabilising agent;
tubulin modulator |
| hexafluorosilicate | [no description available] | medium | 1 | 1 | silicon coordination entity | |
| fluorides | [no description available] | medium | 1 | 1 | halide anion;
monoatomic fluorine | |
| rotenone | [no description available] | medium | 1 | 1 | organic heteropentacyclic compound;
rotenones | antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin |
| coumaphos | [no description available] | high | 1 | 0 | organic thiophosphate;
organochlorine compound;
organothiophosphate insecticide | acaricide;
agrochemical;
antinematodal drug;
avicide;
EC 3.1.1.8 (cholinesterase) inhibitor |
| coumaphos | [no description available] | high | 1 | 1 | organic thiophosphate;
organochlorine compound;
organothiophosphate insecticide | acaricide;
agrochemical;
antinematodal drug;
avicide;
EC 3.1.1.8 (cholinesterase) inhibitor |
| nivalenol | [no description available] | medium | 1 | 0 | trichothecene | |
| triadimefon | [no description available] | medium | 1 | 0 | aromatic ether;
hemiaminal ether;
ketone;
monochlorobenzenes;
triazoles | |
| pyrimethamine | [no description available] | medium | 2 | 1 | aminopyrimidine;
monochlorobenzenes | antimalarial;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor |
| dapsone | [no description available] | medium | 2 | 2 | substituted aniline;
sulfone | anti-inflammatory drug;
antiinfective agent;
antimalarial;
leprostatic drug |
| zinc sulfate | [no description available] | medium | 1 | 1 | metal sulfate;
zinc molecular entity | fertilizer |
| acetonitrile | [no description available] | medium | 1 | 0 | aliphatic nitrile;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent |
| florisil | [no description available] | medium | 1 | 0 | | |
| phencyclidine | [no description available] | medium | 1 | 0 | benzenes;
piperidines | anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug |
| methoxyfenozide | [no description available] | medium | 1 | 0 | carbohydrazide;
monomethoxybenzene | environmental contaminant;
insecticide;
xenobiotic |
| thiodicarb | [no description available] | medium | 2 | 0 | | |
| simazine | [no description available] | medium | 1 | 0 | chloro-1,3,5-triazine;
diamino-1,3,5-triazine | environmental contaminant;
herbicide;
xenobiotic |
| trifluralin | [no description available] | medium | 1 | 0 | (trifluoromethyl)benzenes;
C-nitro compound;
substituted aniline | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| monocrotophos | [no description available] | medium | 1 | 0 | alkenyl phosphate;
dialkyl phosphate;
monocarboxylic acid amide;
organophosphate insecticide | acaricide;
agrochemical;
avicide;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| s 1812 | [no description available] | medium | 1 | 0 | dichlorobenzene;
organochlorine insecticide;
organofluorine insecticide | |
| diethyl maleate | [no description available] | medium | 1 | 0 | ethyl ester;
maleate ester | glutathione depleting agent |
| cyromazine | [no description available] | medium | 1 | 0 | triamino-1,3,5-triazine | mouse metabolite;
triazine insecticide |
| bilirubin | [no description available] | medium | 1 | 0 | biladienes;
dicarboxylic acid | antioxidant;
human metabolite;
mouse metabolite |
| sulfadoxine | [no description available] | medium | 1 | 0 | pyrimidines;
sulfonamide | antibacterial drug;
antimalarial |
| d,d-t80-prallethrin | [no description available] | medium | 1 | 0 | | |
| flucythrinate | [no description available] | medium | 2 | 0 | | |
| phenothrin | [no description available] | medium | 0 | 0 | cyclopropanecarboxylate ester | pyrethroid ester insecticide |
| bioresmethrin | [no description available] | low | 0 | 0 | furans;
resmethrin | pyrethroid ester insecticide |
| transfluthrin | [no description available] | medium | 0 | 0 | carboxylic ester;
cyclopropanes;
organochlorine compound;
organofluorine compound | pyrethroid ester insecticide |
| acrinathrin | [no description available] | medium | 0 | 0 | cyclopropanecarboxylate ester;
organofluorine compound | pyrethroid ester acaricide;
pyrethroid ester insecticide |
| pydrin, (s-(r*,r*))-isomer | [no description available] | low | 0 | 0 | fenvalerate | agrochemical;
pyrethroid ester insecticide |
| parathion | [no description available] | low | 0 | 0 | C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
mouse metabolite |
| 4-(2,4-dichlorophenoxy)butyric acid | [no description available] | medium | 0 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound | agrochemical;
phenoxy herbicide;
synthetic auxin |
| benefin | [no description available] | medium | 0 | 0 | C-nitro compound;
organofluorine compound;
substituted aniline;
tertiary amino compound | agrochemical;
herbicide |
| carbofuran | [no description available] | low | 0 | 0 | 1-benzofurans;
carbamate ester | acaricide;
agrochemical;
avicide;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nematicide |
| dicamba | [no description available] | low | 0 | 0 | dichlorobenzene;
methoxybenzoic acid | agrochemical;
environmental contaminant;
herbicide;
synthetic auxin;
xenobiotic |
| dichlobanil | [no description available] | medium | 0 | 0 | dichlorobenzene;
nitrile | agrochemical;
cellulose synthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic |
| disulfoton | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| ethion | [no description available] | low | 0 | 0 | organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide |
| ethoprophos | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | agrochemical;
antinematodal drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| fenthion | [no description available] | low | 0 | 0 | organic thiophosphate | acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide |
| glyphosate | [no description available] | low | 0 | 0 | glycine derivative;
phosphonic acid | agrochemical;
EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor;
herbicide |
| naled | [no description available] | medium | 0 | 0 | dialkyl phosphate;
organobromine compound;
organochlorine compound;
organophosphate insecticide | acaricide;
agrochemical;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| phorate | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| phosalone | [no description available] | low | 0 | 0 | 1,3-benzoxazoles;
carbamate ester;
organochlorine insecticide;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| roxarsone | [no description available] | low | 0 | 0 | 2-nitrophenols;
organoarsonic acid | agrochemical;
animal growth promotant;
antibacterial drug;
coccidiostat |
| trichlorfon | [no description available] | medium | 0 | 0 | organic phosphonate;
organochlorine compound;
phosphonic ester | agrochemical;
anthelminthic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide |
| famophos | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | agrochemical;
anthelminthic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| dinitrofluorobenzene | [no description available] | medium | 0 | 0 | C-nitro compound;
organofluorine compound | agrochemical;
allergen;
chromatographic reagent;
EC 2.7.3.2 (creatine kinase) inhibitor;
protein-sequencing agent;
spectrophotometric reagent |
| fenuron | [no description available] | low | 0 | 0 | 3-(3,4-substituted-phenyl)-1,1-dimethylurea | agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
xenobiotic |
| glyoxal | [no description available] | low | 0 | 0 | dialdehyde | agrochemical;
allergen;
pesticide;
plant growth regulator |
| fensulfothion | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide;
sulfoxide | agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide |
| pyridafenthion | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide;
pyridazinone | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| linuron | [no description available] | low | 0 | 0 | dichlorobenzene;
phenylureas | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| chlorfenvinphos | [no description available] | low | 0 | 0 | dichlorobenzene;
organic phosphate;
organochlorine acaricide;
organochlorine insecticide;
organophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| bicuculline | [no description available] | low | 0 | 0 | benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines | agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin |
| thiometon | [no description available] | low | 0 | 0 | organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| demeton-s-methyl | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| fonofos | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| metolcarb | [no description available] | low | 0 | 0 | carbamate ester | acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| nitrapyrin | [no description available] | low | 0 | 0 | chloropyridine | agrochemical;
antibacterial agent;
nitrification inhibitor |
| aminocarb | [no description available] | low | 0 | 0 | carbamate ester;
toluenes | acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
molluscicide |
| methiocarb | [no description available] | low | 0 | 0 | aryl sulfide;
carbamate ester;
methyl sulfide | acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
molluscicide;
xenobiotic |
| phenylphosphonothioic acid, 2-ethyl 2-(4-nitrophenyl) ester | [no description available] | low | 0 | 0 | organic phosphonate;
organothiophosphate insecticide;
phosphonic ester | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| lenacil | [no description available] | low | 0 | 0 | cyclopentapyrimidine | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| fluometuron | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
3-(3,4-substituted-phenyl)-1,1-dimethylurea | agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
xenobiotic |
| molinate | [no description available] | low | 0 | 0 | azepanes;
monothiocarbamic ester | agrochemical;
antispermatogenic agent;
herbicide |
| quinomethionate | [no description available] | low | 0 | 0 | dithioloquinoxaline;
quinoxaline acaricide;
quinoxaline antifungal agent | agrochemical |
| mecarbam | [no description available] | low | 0 | 0 | carbamate ester;
organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| phenthoate, (+-)-isomer | [no description available] | low | 0 | 0 | ethyl ester;
organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| isoprocarb | [no description available] | low | 0 | 0 | carbamate ester | agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| cyanophos | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| azinphos ethyl | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| mepiquat | [no description available] | low | 0 | 0 | quaternary ammonium ion | agrochemical;
Maillard reaction product;
plant growth retardant |
| asulam | [no description available] | low | 0 | 0 | carbamate ester;
primary amino compound;
substituted aniline;
sulfonamide | agrochemical;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic |
| sulfotepp | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| bpmc | [no description available] | low | 0 | 0 | carbamate ester | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
herbicide;
insecticide |
| desmedipham | [no description available] | low | 0 | 0 | carbamate ester | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| terbufos | [no description available] | low | 0 | 0 | organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide |
| quinalphos | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| chlortoluron | [no description available] | low | 0 | 0 | monochlorobenzenes;
phenylureas | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| oryzalin | [no description available] | low | 0 | 0 | aromatic amine;
C-nitro compound;
sulfonamide;
tertiary amino compound | agrochemical;
antimitotic;
herbicide |
| methoxuron | [no description available] | low | 0 | 0 | 3-(3,4-substituted-phenyl)-1,1-dimethylurea;
monochlorobenzenes;
monomethoxybenzene | agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
plant growth regulator;
xenobiotic |
| metribuzin | [no description available] | low | 0 | 0 | 1,2,4-triazines;
cyclic ketone;
organic sulfide | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| fenamiphos | [no description available] | low | 0 | 0 | organophosphate insecticide;
organophosphate nematicide;
phosphoramidate ester | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| formetanate | [no description available] | low | 0 | 0 | carbamate ester | acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| pronamide | [no description available] | low | 0 | 0 | benzamides;
dichlorobenzene;
terminal acetylenic compound | agrochemical;
herbicide |
| 2,6-diisopropylnaphthalene | [no description available] | low | 0 | 0 | naphthalenes | agrochemical;
plant growth retardant |
| isofenphos | [no description available] | low | 0 | 0 | isopropyl ester;
organic phosphonate;
organothiophosphate insecticide;
phosphonic ester;
salicylates | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| norflurazone | [no description available] | medium | 0 | 0 | (trifluoromethyl)benzenes;
organochlorine compound;
pyridazinone;
secondary amino compound | agrochemical;
carotenoid biosynthesis inhibitor;
herbicide |
| croneton | [no description available] | low | 0 | 0 | carbamate ester | agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| isoproturon | [no description available] | low | 0 | 0 | 3-(3,4-substituted-phenyl)-1,1-dimethylurea | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| sulprofos | [no description available] | low | 0 | 0 | organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| pendimethalin | [no description available] | low | 0 | 0 | C-nitro compound;
secondary amino compound;
substituted aniline | agrochemical;
environmental contaminant;
herbicide |
| triclopyr | [no description available] | medium | 0 | 0 | aromatic ether;
chloropyridine;
monocarboxylic acid | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| acifluorfen | [no description available] | medium | 0 | 0 | aromatic ether;
benzoic acids;
C-nitro compound;
monocarboxylic acid;
organochlorine compound;
organofluorine compound | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| chlorsulfuron | [no description available] | low | 0 | 0 | methoxy-1,3,5-triazine;
monochlorobenzenes;
N-sulfonylurea | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| deltanit | [no description available] | low | 0 | 0 | 1-benzofurans;
carbamate ester | agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| fomesafen | [no description available] | medium | 0 | 0 | aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| oxadixyl | [no description available] | low | 0 | 0 | anilide fungicide;
aromatic amide;
carbohydrazide;
ether;
oxazolidinone | agrochemical |
| clomazone | [no description available] | low | 0 | 0 | isoxazolidinone;
monochlorobenzenes | agrochemical;
carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic |
| benfuracarb | [no description available] | low | 0 | 0 | 1-benzofurans;
carbamate ester;
ethyl ester | agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| methyl bensulfuron | [no description available] | medium | 0 | 0 | aromatic ether;
methyl ester;
N-sulfonylurea;
pyrimidines | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| chlorimuron ethyl | [no description available] | medium | 0 | 0 | aromatic ether;
ethyl ester;
N-sulfonylurea;
organochlorine pesticide;
pyrimidines;
sulfamoylbenzoate | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide |
| cuprous chloride | [no description available] | low | 0 | 0 | copper molecular entity;
inorganic chloride | agrochemical;
molluscicide |
| nitarsone | [no description available] | low | 0 | 0 | C-nitro compound;
organoarsonic acid | agrochemical;
antiprotozoal drug |
| azamethiphos | [no description available] | low | 0 | 0 | organic thiophosphate;
organochlorine acaricide;
organochlorine insecticide;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| triasulfuron | [no description available] | medium | 0 | 0 | 1,3,5-triazines;
aromatic ether;
N-sulfonylurea;
organochlorine compound | agrochemical;
herbicide |
| isoxaflutole | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ketone;
cyclopropanes;
isoxazoles;
sulfone | agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
proherbicide |
| n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamide | [no description available] | medium | 0 | 0 | dichlorobenzene;
organofluorine compound;
sulfonamide;
triazoles | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| cloransulam-methyl | [no description available] | medium | 0 | 0 | methyl ester;
monochlorobenzenes;
organofluorine compound;
sulfonamide;
triazolopyrimidines | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| bay 93820 | [no description available] | low | 0 | 0 | isopropyl ester;
organic phosphonate;
organothiophosphate insecticide;
phosphonic ester;
salicylates | agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| raiser | [no description available] | medium | 0 | 0 | (trifluoromethyl)benzenes;
organochlorine compound;
pyrrolidines | agrochemical;
carotenoid biosynthesis inhibitor;
herbicide |
| quinclorac | [no description available] | medium | 0 | 0 | monocarboxylic acid;
organochlorine compound;
quinolinemonocarboxylic acid | agrochemical;
herbicide;
synthetic auxin |
| cadusafos | [no description available] | low | 0 | 0 | organic thiophosphate;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide |
| fosthiazate | [no description available] | low | 0 | 0 | organic phosphonate;
organothiophosphate insecticide;
phosphonic ester | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide |
| aclonifen | [no description available] | medium | 0 | 0 | aromatic ether;
C-nitro compound;
monochlorobenzenes;
primary amino compound;
substituted aniline | agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| s 53482 | [no description available] | medium | 0 | 0 | benzoxazine;
dicarboximide;
organofluorine compound;
terminal acetylenic compound | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide;
teratogenic agent |
| clodinafop-propargyl | [no description available] | medium | 0 | 0 | aromatic ether;
carboxylic ester;
organochlorine compound;
organofluorine compound;
propyzamide;
pyridines | agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
herbicide |
| triflusulfuron-methyl | [no description available] | medium | 0 | 0 | 1,3,5-triazines;
aromatic ether;
benzoate ester;
methyl ester;
N-sulfonylurea;
organofluorine compound;
tertiary amino compound | agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide |
| pyraclofos | [no description available] | low | 0 | 0 | monochlorobenzenes;
organic thiophosphate;
organochlorine insecticide;
organosulfur compound;
organothiophosphate insecticide;
pyrazoles | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| 1-methylcyclopropene | [no description available] | low | 0 | 0 | cycloalkene;
cyclopropenes | agrochemical;
plant growth regulator |
| cafenstrole | [no description available] | low | 0 | 0 | benzenes;
sulfone;
triazoles | agrochemical;
antimitotic;
herbicide |
| pinoxaden | [no description available] | low | 0 | 0 | pivalate ester;
pyrazolooxadiazepine | agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
environmental contaminant;
proherbicide;
xenobiotic |
| tioxazafen | [no description available] | low | 0 | 0 | 1,2,4-oxadiazole;
thiophenes | agrochemical;
nematicide |
| tetrachlorvinphos | [no description available] | low | 0 | 0 | alkenyl phosphate;
dialkyl phosphate;
organochlorine insecticide;
organophosphate insecticide;
trichlorobenzene | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| propetamphos | [no description available] | low | 0 | 0 | isopropyl ester;
organophosphate insecticide;
phosphoramidate ester | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| tolfenpyrad | [no description available] | medium | 0 | 0 | aromatic amide;
aromatic ether;
organochlorine compound;
pyrazole insecticide | agrochemical;
antifungal agent;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor |
| fluensulfone | [no description available] | low | 0 | 0 | 1,3-thiazoles;
olefinic compound;
organochlorine pesticide;
organofluorine pesticide;
sulfone | agrochemical;
nematicide |
| tembotrione | [no description available] | medium | 0 | 0 | aromatic ketone;
beta-triketone;
cyclic ketone;
ether;
monochlorobenzenes;
organofluorine compound;
sulfone | agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide |
| haloxyfop-P-methyl | [no description available] | low | 0 | 0 | methyl 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate | agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
proherbicide |
| alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile) | [no description available] | medium | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ketone;
beta-diketone;
cyclopropanes;
nitrile;
sulfone | agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide |
| cyenopyrafen | [no description available] | medium | 0 | 0 | nitrile;
pivalate ester;
pyrazoles | agrochemical;
proacaricide |
| fluazaindolizine | [no description available] | low | 0 | 0 | aromatic amide;
imidazopyridine;
monocarboxylic acid amide;
monochlorobenzenes;
monomethoxybenzene;
N-sulfonylcarboxamide;
organofluorine pesticide | agrochemical;
nematicide |
| afidopyropen | [no description available] | medium | 0 | 0 | cyclopropanecarboxylate ester;
organic heterotetracyclic compound;
pyridines;
secondary alcohol | agrochemical;
insecticide;
TRPV channel modulator |
| quinacrine | [no description available] | low | 0 | 0 | acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound | antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor |
| vanilmandelic acid | [no description available] | low | 0 | 0 | 2-hydroxy monocarboxylic acid;
aromatic ether;
phenols | human metabolite |
| win 52035 | [no description available] | low | 0 | 0 | aromatic ether | |
| win 52084 | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(nonyloxy)tryptamine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
tryptamines | serotonergic agonist |
| methylbufotenin | [no description available] | low | 0 | 0 | aromatic ether;
tertiary amino compound;
tryptamine alkaloid | hallucinogen;
plant metabolite |
| 5-methoxytryptamine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
tryptamines | 5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist |
| ro 48-8071 | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
bromobenzenes;
monofluorobenzenes;
olefinic compound;
tertiary amino compound | antineoplastic agent;
EC 5.4.99.7 (lanosterol synthase) inhibitor |
| rtki cpd | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
quinazolines | antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector |
| amsacrine | [no description available] | low | 0 | 0 | acridines;
aromatic ether;
sulfonamide | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor |
| aristolochic acid i | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin |
| 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one | [no description available] | low | 0 | 0 | aromatic ether;
benzoxazine;
cyclic hydroxamic acid;
lactol | allelochemical;
plant metabolite |
| bufetolol | [no description available] | low | 0 | 0 | aromatic ether | |
| bufexamac | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid | antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| bunitrolol | [no description available] | low | 0 | 0 | aromatic ether | |
| bupranolol | [no description available] | low | 0 | 0 | aromatic ether | |
| verapamil | [no description available] | low | 0 | 0 | aromatic ether;
nitrile;
polyether;
tertiary amino compound | |
| cgp 12177 | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
secondary alcohol;
secondary amino compound | beta-adrenergic antagonist |
| ciglitazone | [no description available] | low | 0 | 0 | aromatic ether;
thiazolidinone | antineoplastic agent;
insulin-sensitizing drug |
| cirazoline | [no description available] | low | 0 | 0 | aromatic ether | |
| clofibrate | [no description available] | low | 0 | 0 | aromatic ether;
ethyl ester;
monochlorobenzenes | anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist |
| clofibric acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist |
| colchicine, (+-)-isomer | [no description available] | low | 0 | 0 | acetamides;
alkaloid;
aromatic ether;
carbotricyclic compound | microtubule-destabilising agent;
plant metabolite |
| croconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole antifungal drug;
imidazole antifungal drug;
monochlorobenzenes | |
| racemethorphan | [no description available] | low | 0 | 0 | aromatic ether;
morphinane alkaloid;
morphinane-like compound;
organic heterotetracyclic compound | |
| dibucaine | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
tertiary amino compound | topical anaesthetic |
| dilacor xr | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
benzothiazepine;
lactam;
tertiary amino compound | |
| domiphen | [no description available] | low | 0 | 0 | aromatic ether | |
| donepezil | [no description available] | low | 0 | 0 | aromatic ether;
indanones;
piperidines;
racemate | EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent |
| epirizole | [no description available] | low | 0 | 0 | aromatic ether | |
| ethoxyquin | [no description available] | low | 0 | 0 | aromatic ether;
quinolines | antifungal agrochemical;
food antioxidant;
genotoxin;
geroprotector;
herbicide;
Hsp90 inhibitor;
neuroprotective agent;
UDP-glucuronosyltransferase activator |
| ethoxzolamide | [no description available] | low | 0 | 0 | aromatic ether;
benzothiazoles;
sulfonamide | antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor |
| 2-hexyloxybenzamide | [no description available] | low | 0 | 0 | aromatic ether;
benzamides | antifungal agent |
| carbonyl cyanide p-trifluoromethoxyphenylhydrazone | [no description available] | low | 0 | 0 | aromatic ether;
hydrazone;
nitrile;
organofluorine compound | ATP synthase inhibitor;
geroprotector;
ionophore |
| fenofibrate | [no description available] | low | 0 | 0 | aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes | antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic |
| flecainide | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
organofluorine compound;
piperidines | anti-arrhythmia drug |
| fluoxetine | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound | |
| gallamine triethiodide | [no description available] | low | 0 | 0 | aromatic ether | |
| gemfibrozil | [no description available] | low | 0 | 0 | aromatic ether | antilipemic drug |
| haloprogin | [no description available] | low | 0 | 0 | aromatic ether | |
| indomethacin | [no description available] | low | 0 | 0 | aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole | analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic |
| ipriflavone | [no description available] | low | 0 | 0 | aromatic ether;
isoflavones | bone density conservation agent |
| ly 171883 | [no description available] | low | 0 | 0 | acetophenones;
aromatic ether;
phenols;
tetrazoles | anti-asthmatic drug;
leukotriene antagonist |
| mephenesin | [no description available] | low | 0 | 0 | aromatic ether;
glycerol ether | |
| methocarbamol | [no description available] | low | 0 | 0 | aromatic ether;
carbamate ester;
secondary alcohol | |
| methoctramine | [no description available] | low | 0 | 0 | aromatic ether;
tetramine | muscarinic antagonist |
| metoprolol | [no description available] | low | 0 | 0 | aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound | antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic |
| mexiletine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound | anti-arrhythmia drug |
| midodrine | [no description available] | low | 0 | 0 | amino acid amide;
aromatic ether;
secondary alcohol | alpha-adrenergic agonist;
prodrug;
sympathomimetic agent;
vasoconstrictor agent |
| clorgyline | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
terminal acetylenic compound;
tertiary amino compound | antidepressant;
EC 1.4.3.4 (monoamine oxidase) inhibitor |
| nefazodone | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles | alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor |
| nimesulide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
sulfonamide | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug |
| nisoxetine | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound | adrenergic uptake inhibitor;
antidepressant |
| n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
sulfonamide | antineoplastic agent;
cyclooxygenase 2 inhibitor |
| omeprazole | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
pyridines;
sulfoxide | |
| oxprenolol | [no description available] | low | 0 | 0 | aromatic ether | |
| pantoprazole | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
organofluorine compound;
pyridines;
sulfoxide | anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
environmental contaminant;
xenobiotic |
| pd 153035 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
bromobenzenes;
quinazolines;
secondary amino compound | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist |
| pentamidine | [no description available] | low | 0 | 0 | aromatic ether;
carboxamidine;
diether | anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic |
| phenacetin | [no description available] | low | 0 | 0 | acetamides;
aromatic ether | cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug |
| pioglitazone | [no description available] | low | 0 | 0 | aromatic ether;
pyridines;
thiazolidinediones | antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic |
| piretanide | [no description available] | low | 0 | 0 | aromatic ether | |
| pramoxine | [no description available] | low | 0 | 0 | aromatic ether;
morpholines | local anaesthetic |
| prazosin | [no description available] | low | 0 | 0 | aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines | alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor |
| primaquine | [no description available] | low | 0 | 0 | aminoquinoline;
aromatic ether;
N-substituted diamine | antimalarial |
| proglumetacin | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
carboxylic ester;
monochlorobenzenes;
N-acylindole;
N-alkylpiperazine | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug |
| pyrilamine | [no description available] | low | 0 | 0 | aromatic ether;
ethylenediamine derivative | H1-receptor antagonist |
| sulfadimethoxine | [no description available] | low | 0 | 0 | aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide | antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic |
| tetrahydropapaverine | [no description available] | low | 0 | 0 | aromatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
polyether;
secondary amino compound | |
| tilorone | [no description available] | low | 0 | 0 | aromatic ether;
diether;
fluoren-9-ones;
tertiary amino compound | anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
interferon inducer;
nicotinic acetylcholine receptor agonist |
| ultram | [no description available] | low | 0 | 0 | aromatic ether;
tertiary alcohol;
tertiary amino compound | |
| triclosan | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols | antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic |
| viloxazine | [no description available] | low | 0 | 0 | aromatic ether | |
| wb 4101 | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxine;
secondary amino compound | alpha-adrenergic antagonist |
| 3,3',5-triiodothyropropionic acid | [no description available] | low | 0 | 0 | aromatic ether | |
| methacetin | [no description available] | low | 0 | 0 | acetamides;
aromatic ether | |
| mestranol | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound | prodrug;
xenoestrogen |
| visnagin | [no description available] | low | 0 | 0 | aromatic ether;
furanochromone;
polyketide | anti-inflammatory agent;
antihypertensive agent;
EC 1.1.1.37 (malate dehydrogenase) inhibitor;
phytotoxin;
plant metabolite;
vasodilator agent |
| 2-tert-butyl-4-hydroxyanisole | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| mecoprop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | |
| phenetidine | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| 2-methyl-4-chlorophenoxy gamma-butyric acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | environmental contaminant;
phenoxy herbicide;
xenobiotic |
| 4-bromophenyl phenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| di-(4-aminophenyl)ether | [no description available] | low | 0 | 0 | aromatic ether | |
| phenyl ether | [no description available] | low | 0 | 0 | aromatic ether | plant metabolite |
| diglycidyl resorcinol ether | [no description available] | low | 0 | 0 | aromatic ether | |
| phenetole | [no description available] | low | 0 | 0 | aromatic ether | |
| scoparone | [no description available] | low | 0 | 0 | aromatic ether;
coumarins | anti-allergic agent;
anti-inflammatory agent;
antihypertensive agent;
antilipemic drug;
immunosuppressive agent;
plant metabolite |
| dimethoxyphenylethylamine | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
phenylethylamine | allergen;
plant metabolite |
| dichlorprop | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
monocarboxylic acid | |
| 3-tert-butyl-4-hydroxyanisole | [no description available] | low | 0 | 0 | aromatic ether;
phenols | antioxidant;
human xenobiotic metabolite |
| ethyl vanillin | [no description available] | low | 0 | 0 | aromatic ether;
benzaldehydes;
phenols | antioxidant;
flavouring agent |
| benzethonium chloride | [no description available] | low | 0 | 0 | aromatic ether;
chloride salt;
quaternary ammonium salt | antibacterial agent;
antifungal agent;
antiseptic drug;
antiviral agent;
disinfectant |
| peucedanin | [no description available] | low | 0 | 0 | aromatic ether;
furanocoumarin;
lactone | plant metabolite |
| phenetidine | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
substituted aniline | drug metabolite |
| 6-methoxybenzoxazolinone | [no description available] | low | 0 | 0 | aromatic ether;
benzoxazole | antibacterial agent;
anticonvulsant;
antifungal agent;
muscle relaxant;
plant metabolite |
| 3-anisidine | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| domiphen bromide | [no description available] | low | 0 | 0 | aromatic ether | |
| dibrompropamidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-Ethoxyphenol | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| bulbocapnine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
oxacycle;
phenols | EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
EC 1.4.3.22 (diamine oxidase) inhibitor;
plant metabolite |
| benzydamine | [no description available] | low | 0 | 0 | aromatic ether;
indazoles;
tertiary amino compound | analgesic;
central nervous system stimulant;
hallucinogen;
local anaesthetic;
non-steroidal anti-inflammatory drug |
| xylocholine | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-methoxycatechol | [no description available] | low | 0 | 0 | aromatic ether;
catechols | G-protein-coupled receptor agonist |
| 2-phenoxypropanoic acid | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic acid | |
| 6-methoxyquinoline | [no description available] | low | 0 | 0 | aromatic ether;
quinolines | |
| metaxalone | [no description available] | low | 0 | 0 | aromatic ether | |
| heliamine | [no description available] | low | 0 | 0 | aromatic ether;
diether;
isoquinoline alkaloid;
isoquinolines | plant metabolite |
| 2,4,6-trichlorophenyl 4-nitrophenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
chlorobenzenes | EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| etridiazol | [no description available] | low | 0 | 0 | aromatic ether;
organochlorine compound;
thiadiazole antifungal agent;
thiadiazoles | antifungal agrochemical;
nitrification inhibitor |
| toliprolol | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-methoxyindoleacetic acid | [no description available] | low | 0 | 0 | aromatic ether;
indole-3-acetic acids | antibacterial agent;
Brassica napus metabolite;
carcinogenic agent;
human urinary metabolite;
marine xenobiotic metabolite;
rat metabolite |
| iproclozide | [no description available] | low | 0 | 0 | aromatic ether | |
| phenoxyacetic acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid | allergen;
Aspergillus metabolite;
human xenobiotic metabolite;
plant growth retardant |
| nafenopin | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid | |
| methyl vanillate | [no description available] | low | 0 | 0 | aromatic ether;
benzoate ester;
phenols | antioxidant;
plant metabolite |
| 5-methoxyindole-2-carboxylic acid | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxylic acid | EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor;
hypoglycemic agent;
plant metabolite |
| 2-isopropoxyphenol | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| dehydroemetine | [no description available] | low | 0 | 0 | aromatic ether;
isoquinolines;
pyridoisoquinoline | antileishmanial agent;
antimalarial;
antiprotozoal drug |
| 1,2-epoxy-3-(p-nitrophenoxy)propane | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
epoxide | |
| laurolitsine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
phenols | HIV-1 integrase inhibitor;
metabolite |
| metocurine iodide | [no description available] | low | 0 | 0 | aromatic ether | |
| ac 45594 | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-phenoxybenzylalcohol | [no description available] | low | 0 | 0 | aromatic ether;
benzyl alcohols | marine xenobiotic metabolite |
| devrinol | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
naphthalenes | |
| fluorodifen | [no description available] | low | 0 | 0 | aromatic ether | |
| acridine half-mustard | [no description available] | low | 0 | 0 | aminoacridines;
aromatic ether;
organochlorine compound;
secondary amino compound | mutagen |
| precocene i | [no description available] | low | 0 | 0 | aromatic ether;
chromenes | plant metabolite;
precocenes |
| oxadiazon | [no description available] | low | 0 | 0 | aromatic ether | |
| lofexidine | [no description available] | low | 0 | 0 | aromatic ether;
carboxamidine;
dichlorobenzene;
imidazoles | alpha-adrenergic agonist;
antihypertensive agent |
| alclofenac | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | drug allergen;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| phenylglycidyl ether | [no description available] | low | 0 | 0 | aromatic ether | |
| phenoxyethanol | [no description available] | low | 0 | 0 | aromatic ether;
glycol ether;
primary alcohol | antiinfective agent;
central nervous system depressant |
| metipranolol | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
propanolamine;
secondary amino compound | anti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist |
| silybin | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxine;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone | antineoplastic agent;
antioxidant;
hepatoprotective agent;
plant metabolite |
| oxamethacin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
N-acylindole;
organochlorine compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| canadine | [no description available] | low | 0 | 0 | aromatic ether;
berberine alkaloid;
organic heteropentacyclic compound;
oxacycle | |
| 7-ethoxycoumarin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins | |
| medifoxamine | [no description available] | low | 0 | 0 | aromatic ether | |
| chlormethoxynil | [no description available] | low | 0 | 0 | aromatic ether | |
| climbazole | [no description available] | low | 0 | 0 | aromatic ether;
hemiaminal ether;
imidazoles;
ketone;
monochlorobenzenes | |
| 4-hexyloxyaniline | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| ticrynafen | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes | antihypertensive agent;
hepatotoxic agent;
loop diuretic |
| 2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
diether;
monocarboxylic acid | |
| bezafibrate | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes | antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic |
| levobunolol | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
propanolamine | antiglaucoma drug;
beta-adrenergic antagonist |
| dichlorfop-methyl | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
diether;
methyl ester | |
| triadimenol | [no description available] | low | 0 | 0 | aromatic ether;
conazole fungicide;
hemiaminal ether;
monochlorobenzenes;
secondary alcohol;
triazole fungicide | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
xenobiotic metabolite |
| prenalterol | [no description available] | low | 0 | 0 | aromatic ether | |
| st 1059 | [no description available] | low | 0 | 0 | aromatic ether;
primary amino compound;
secondary alcohol | alpha-adrenergic agonist;
sympathomimetic agent;
vasoconstrictor agent |
| paroxetine | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
organofluorine compound;
piperidines | antidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor |
| bopindolol | [no description available] | low | 0 | 0 | aromatic ether;
benzoate ester;
methylindole;
secondary amino compound | |
| flutolanil | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
benzamides;
benzanilide fungicide | antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| fenoxaprop ethyl | [no description available] | low | 0 | 0 | aromatic ether | |
| triclabendazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound | environmental contaminant;
herbicide;
xenobiotic |
| quizalofop-ethyl | [no description available] | low | 0 | 0 | aromatic ether;
ethyl ester;
organochlorine compound;
quinoxaline derivative | |
| cetamolol | [no description available] | low | 0 | 0 | aromatic ether | |
| atomoxetine | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound;
toluenes | adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic |
| itraconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole antifungal drug;
cyclic ketal;
dichlorobenzene;
dioxolane;
N-arylpiperazine;
triazole antifungal drug;
triazoles | EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
Hedgehog signaling pathway inhibitor;
P450 inhibitor |
| loxtidine | [no description available] | low | 0 | 0 | aromatic ether;
piperidines;
primary alcohol;
triazoles | H2-receptor antagonist |
| disoxaril | [no description available] | low | 0 | 0 | aromatic ether | |
| tepoxalin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
monochlorobenzenes;
pyrazoles | antipyretic;
apoptosis inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
immunomodulator;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| esmolol | [no description available] | low | 0 | 0 | aromatic ether;
ethanolamines;
methyl ester;
secondary alcohol;
secondary amino compound | |
| pioglitazone hydrochloride | [no description available] | low | 0 | 0 | aromatic ether | |
| aripiprazole | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactam;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
quinolone | drug metabolite;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic agonist |
| sulfametrole | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline;
sulfonamide antibiotic;
thiadiazoles | |
| propamidine | [no description available] | low | 0 | 0 | aromatic ether;
guanidines;
polyether | antimicrobial agent;
antiseptic drug |
| hexamidine | [no description available] | low | 0 | 0 | aromatic ether;
guanidines;
polyether | antimicrobial agent;
antiseptic drug |
| o-4-methylthymine | [no description available] | low | 0 | 0 | aromatic ether;
methylthymine | human metabolite |
| fenclofenac | [no description available] | low | 0 | 0 | aromatic ether | |
| tetraiodothyroacetic acid | [no description available] | low | 0 | 0 | 2-halophenol;
aromatic ether;
iodophenol;
monocarboxylic acid | apoptosis inducer;
human metabolite;
thyroid hormone |
| fluazuron | [no description available] | low | 0 | 0 | aromatic ether;
chloropyridine;
monochlorobenzenes;
N-acylurea;
organochlorine acaricide;
organofluorine acaricide;
phenylureas | acaricide;
mite growth regulator |
| etiroxate | [no description available] | low | 0 | 0 | aromatic ether | |
| etofamide | [no description available] | low | 0 | 0 | aromatic ether | |
| d 888 | [no description available] | low | 0 | 0 | aromatic ether;
nitrile;
tertiary amino compound | anti-arrhythmia drug;
calcium channel blocker;
vasodilator agent |
| esreboxetine | [no description available] | low | 0 | 0 | aromatic ether | |
| guaethol | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
volatile organic compound | flavouring agent |
| spiramide | [no description available] | low | 0 | 0 | aromatic ether;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound | dopaminergic antagonist;
serotonergic antagonist |
| 5'-nitro-2'-propoxyacetanilide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| suberosin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins | anticoagulant;
plant metabolite |
| 4-methoxyestradiol | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
phenols | estrogen;
human metabolite;
rat metabolite |
| toltrazuril | [no description available] | low | 0 | 0 | aromatic ether | |
| plafibride | [no description available] | low | 0 | 0 | aromatic ether | |
| cinitapride | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| isoscopoletin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxycoumarin | plant metabolite |
| uk 68798 | [no description available] | low | 0 | 0 | aromatic ether;
sulfonamide;
tertiary amino compound | anti-arrhythmia drug;
potassium channel blocker |
| hp 873 | [no description available] | low | 0 | 0 | 1,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound | dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist |
| fenoxypropazine | [no description available] | low | 0 | 0 | aromatic ether | |
| amezinium | [no description available] | low | 0 | 0 | aromatic ether;
primary arylamine;
pyridazinium ion | adrenergic uptake inhibitor;
antihypotensive agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
sympathomimetic agent |
| rubrofusarin | [no description available] | low | 0 | 0 | aromatic ether;
benzochromenone;
phenols;
polyketide | biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
fungal metabolite |
| dauricine | [no description available] | low | 0 | 0 | aromatic ether;
bisbenzylisoquinoline alkaloid;
isoquinolines;
phenols;
tertiary amino compound | plant metabolite |
| uvaretin | [no description available] | low | 0 | 0 | aromatic ether;
dihydrochalcones;
polyketide;
resorcinol | antineoplastic agent;
plant metabolite |
| fangchinoline | [no description available] | low | 0 | 0 | aromatic ether;
bisbenzylisoquinoline alkaloid;
macrocycle | anti-HIV-1 agent;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
neuroprotective agent;
plant metabolite |
| prochloraz | [no description available] | low | 0 | 0 | amide fungicide;
aromatic ether;
conazole fungicide;
imidazole fungicide;
imidazoles;
trichlorobenzene;
ureas | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic |
| stictic acid | [no description available] | low | 0 | 0 | aromatic ether | |
| pramoxine hydrochloride | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-methoxybenzylamine | [no description available] | low | 0 | 0 | aralkylamino compound;
aromatic ether;
primary amino compound | |
| xanthurenic acid 8-methyl ether | [no description available] | low | 0 | 0 | aromatic ether;
monohydroxyquinoline;
quinolinemonocarboxylic acid | carcinogenic agent;
metabolite;
mouse metabolite |
| adriamycinol | [no description available] | low | 0 | 0 | aminoglycoside;
anthracycline antibiotic;
aromatic ether;
deoxy hexoside;
p-quinones;
phenols;
polyol;
tetracenequinones | cardiotoxic agent;
drug metabolite |
| difenoconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole fungicide;
cyclic ketal;
dioxolane;
triazole fungicide;
triazoles | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic |
| a 8947 | [no description available] | low | 0 | 0 | aromatic ether;
biaryl;
N-sulfonylurea;
pyrazole pesticide;
tetrazoles | EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| thifluzamide | [no description available] | low | 0 | 0 | 1,3-thiazoles;
anilide fungicide;
aromatic amide;
aromatic ether;
dibromobenzene;
organofluorine compound | antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| ethylhydrocupreine | [no description available] | low | 0 | 0 | aromatic ether;
cinchona alkaloid | EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor |
| 7,8-dihydromethysticin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| 4,5-dimethoxy-2-nitrobenzaldehyde | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| bisphenol f diglycidyl ether | [no description available] | low | 0 | 0 | aromatic ether;
diarylmethane;
epoxide | |
| oryzemate | [no description available] | low | 0 | 0 | 1,2-benzisothiazole;
aromatic ether;
benzothiazole fungicide;
sulfone | antifungal agrochemical;
plant activator |
| bitertanol | [no description available] | low | 0 | 0 | aromatic ether;
biphenyls;
secondary alcohol;
triazoles | |
| fluazifop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organofluorine compound;
pyridines | |
| diflufenican | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
pyridinecarboxamide | carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic |
| diethofencarb | [no description available] | low | 0 | 0 | aromatic ether;
carbamate ester;
carbanilate fungicide | antifungal agrochemical |
| methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoate | [no description available] | low | 0 | 0 | aromatic ether;
benzoate ester;
diamino-1,3,5-triazine;
methyl ester;
N-sulfonylurea | EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide |
| dpx e9636 | [no description available] | low | 0 | 0 | aromatic ether;
N-sulfonylurea;
pyridines;
pyrimidines;
sulfone | environmental contaminant;
herbicide;
xenobiotic |
| cinosulfuron | [no description available] | low | 0 | 0 | aromatic ether | |
| vestitol | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | anti-inflammatory agent;
phytoalexin;
plant metabolite |
| laudanine | [no description available] | low | 0 | 0 | aromatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
phenols;
racemate | |
| cryptopleurine | [no description available] | low | 0 | 0 | alkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound | antineoplastic agent;
antiviral agent;
protein synthesis inhibitor |
| 6-hydroxymethylmexiletine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-hydroxymexiletine | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| cloquintocet-mexyl | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic ester;
organochlorine compound;
quinolines | |
| bursehernin | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
butan-4-olide;
lignan | plant metabolite |
| 2,2',4,4'-tetrabromodiphenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| allocryptopine | [no description available] | low | 0 | 0 | aromatic ether;
cyclic acetal;
cyclic ketone;
dibenzazecine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound | |
| sporidesmin | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
diketone;
organic disulfide;
organic heteropentacyclic compound;
organochlorine compound;
secondary alcohol;
tertiary alcohol;
tertiary amino compound | mycotoxin;
Wnt signalling activator |
| syringaresinol | [no description available] | low | 0 | 0 | aromatic ether;
furofuran;
lignan;
polyether;
polyphenol | plant metabolite |
| p-methoxy-n-methylphenethylamine | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound | metabolite |
| aflatoxin q1 | [no description available] | low | 0 | 0 | aflatoxin;
aromatic ether;
aromatic ketone | carcinogenic agent;
human xenobiotic metabolite |
| u 73122 | [no description available] | low | 0 | 0 | aromatic ether;
aza-steroid;
maleimides | EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor |
| norverapamil | [no description available] | low | 0 | 0 | aromatic ether;
nitrile;
polyether;
secondary amino compound | |
| fumitremorgin a | [no description available] | low | 0 | 0 | aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide | mycotoxin |
| deguelin | [no description available] | low | 0 | 0 | aromatic ether;
diether;
organic heteropentacyclic compound;
rotenones | angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor;
plant metabolite |
| aristolochic acid ii | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin |
| tephrosin | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
organic heteropentacyclic compound;
rotenones | antineoplastic agent;
metabolite;
pesticide |
| alpha-hydroxymetoprolol | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(tetradecyloxy)-2-furancarboxylic acid | [no description available] | low | 0 | 0 | aromatic ether;
furoic acid | antineoplastic agent;
apoptosis inducer;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
PPARalpha agonist |
| tafenoquine | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aminoquinoline;
aromatic ether;
primary amino compound;
secondary amino compound | |
| 5-hydroxymethylomeprazole | [no description available] | low | 0 | 0 | aromatic ether;
benzimidazoles;
pyridines;
sulfoxide | drug metabolite |
| mosapride | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
secondary carboxamide;
substituted aniline;
tertiary amino compound | |
| ym 12617 | [no description available] | low | 0 | 0 | aromatic ether;
secondary amino compound;
sulfonamide | |
| gefitinib | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound | antineoplastic agent;
epidermal growth factor receptor antagonist |
| cgp 28392 | [no description available] | low | 0 | 0 | aromatic ether | |
| sodium-binding benzofuran isophthalate | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
crown compound;
tetracarboxylic acid | fluorochrome |
| garenoxacin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
isoindoles;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic | antibacterial drug;
non-steroidal anti-inflammatory drug |
| ay 25545 | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
C-glycosyl compound;
naphthoisochromene;
olefinic compound;
phenols;
tertiary amine | antimicrobial agent;
antineoplastic agent;
bacterial metabolite |
| reboxetine | [no description available] | low | 0 | 0 | aromatic ether | |
| b 823-08 | [no description available] | low | 0 | 0 | aromatic ether | |
| cyclazosin | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
furans;
monocarboxylic acid amide;
quinazolines;
quinoxaline derivative | adenosine A2A receptor antagonist |
| ivabradine | [no description available] | low | 0 | 0 | aromatic ether;
benzazepine;
carbobicyclic compound;
tertiary amino compound | cardiotonic drug |
| febuxostat | [no description available] | low | 0 | 0 | 1,3-thiazolemonocarboxylic acid;
aromatic ether;
nitrile | EC 1.17.3.2 (xanthine oxidase) inhibitor |
| marsupsin | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
polyphenol | antilipemic drug;
hypoglycemic agent;
metabolite |
| 6,6'-bieckol | [no description available] | low | 0 | 0 | aromatic ether;
oxacycle;
phlorotannin | anti-HIV-1 agent;
metabolite;
radical scavenger |
| xibenolol | [no description available] | low | 0 | 0 | aromatic ether | |
| cicloprolol | [no description available] | low | 0 | 0 | aromatic ether | |
| chs 828 | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-methoxyphenoxy)propanoic acid | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic acid | |
| moxifloxacin | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
fluoroquinolone antibiotic;
pyrrolidinopiperidine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone | antibacterial drug |
| rp 73401 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
chloropyridine;
monocarboxylic acid amide | anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
phosphodiesterase IV inhibitor |
| 2,2',4,4',5,5'-hexabrominated diphenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| varespladib | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
dicarboxylic acid monoamide;
indoles;
monocarboxylic acid;
primary carboxamide | anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor |
| birb 796 | [no description available] | low | 0 | 0 | aromatic ether;
morpholines;
naphthalenes;
pyrazoles;
ureas | EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
immunomodulator |
| schizandrin b | [no description available] | low | 0 | 0 | aromatic ether;
cyclic acetal;
organic heterotetracyclic compound;
oxacycle;
tannin | anti-asthmatic agent;
anti-inflammatory agent;
antilipemic drug;
antioxidant;
apoptosis inhibitor;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
plant metabolite |
| s 23121 | [no description available] | low | 0 | 0 | aromatic ether;
dicarboximide;
monochlorobenzenes;
monofluorobenzenes;
pyrroline;
terminal acetylenic compound | |
| acrovestone | [no description available] | low | 0 | 0 | acetophenones;
aromatic ether;
olefinic compound;
polyphenol | antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite |
| corytuberine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
organic heterotetracyclic compound;
polyphenol;
tertiary amino compound | plant metabolite |
| actinodaphine | [no description available] | low | 0 | 0 | aporphine alkaloid;
aromatic ether;
organic heteropentacyclic compound;
phenols;
secondary amino compound | antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite;
platelet aggregation inhibitor;
topoisomerase inhibitor |
| isohomovanillic acid | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
phenylacetic acids | metabolite |
| 3,5-diiodothyropropionic acid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organoiodine compound;
phenols | |
| 7,8-dihydro-5,6-dehydrokawain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| 4-amino-2-methoxypyrimidine | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
methylcytosine | metabolite |
| aristolochic acid D | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
nephrotoxin;
toxin |
| myricanone | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
diarylheptanoid;
methoxybenzenes;
phenols | antineoplastic agent;
plant metabolite |
| pannarin | [no description available] | low | 0 | 0 | aldehyde;
aromatic ether;
depsidones;
organic heterotricyclic compound;
organochlorine compound;
phenols | antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
lichen metabolite |
| aminopotentidine | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
guanidines;
nitrile;
piperidines;
substituted aniline | H2-receptor antagonist |
| aristolochic acid c | [no description available] | low | 0 | 0 | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin |
| pluviatolide | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
butan-4-olide;
lignan;
phenols | plant metabolite |
| erysodine | [no description available] | low | 0 | 0 | aromatic ether;
diether;
Erythrina alkaloid;
organic heterotetracyclic compound;
phenols | antiparasitic agent;
nicotinic antagonist;
phytogenic insecticide |
| erlotinib | [no description available] | low | 0 | 0 | aromatic ether;
quinazolines;
secondary amino compound;
terminal acetylenic compound | antineoplastic agent;
epidermal growth factor receptor antagonist;
protein kinase inhibitor |
| rubrofusarin B | [no description available] | low | 0 | 0 | aromatic ether;
benzochromenone;
naphtho-gamma-pyrone;
phenols;
polyketide | Aspergillus metabolite |
| ly 293111 | [no description available] | low | 0 | 0 | aromatic ether | |
| enrasentan | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
indanes;
monocarboxylic acid;
monomethoxybenzene;
primary alcohol | antihypertensive agent;
endothelin receptor antagonist |
| quizalofop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound;
quinoxaline derivative | |
| cyhalofop-butyl | [no description available] | low | 0 | 0 | aromatic ether | |
| cyperin | [no description available] | low | 0 | 0 | aromatic ether | |
| aflatoxin b1 | [no description available] | low | 0 | 0 | aflatoxin;
aromatic ether;
aromatic ketone | carcinogenic agent;
human metabolite |
| etravirine | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
dinitrile;
organobromine compound | antiviral agent;
HIV-1 reverse transcriptase inhibitor |
| 5-o-methyllicoricidin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | antibacterial agent;
plant metabolite |
| pronuciferine | [no description available] | low | 0 | 0 | aromatic ether;
cyclic ketone;
isoquinoline alkaloid;
isoquinolines;
organic heterotetracyclic compound | plant metabolite |
| dronedarone | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound | anti-arrhythmia drug;
environmental contaminant;
xenobiotic |
| famoxadone | [no description available] | low | 0 | 0 | aromatic ether;
carbohydrazide;
oxazolidinone | |
| cimicoxib | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
organochlorine compound;
organofluorine compound;
sulfonamide | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug |
| sorafenib | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
phenylureas;
pyridinecarboxamide | angiogenesis inhibitor;
anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
ferroptosis inducer;
tyrosine kinase inhibitor |
| dabuzalgron | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
monochlorobenzenes;
sulfonamide | alpha-adrenergic agonist |
| fonsecin | [no description available] | low | 0 | 0 | aromatic ether;
cyclic hemiketal;
heptaketide;
naphtho-gamma-pyrone;
phenols | Aspergillus metabolite;
marine metabolite |
| lasofoxifene | [no description available] | low | 0 | 0 | aromatic ether;
N-alkylpyrrolidine;
naphthols;
tetralins | antineoplastic agent;
bone density conservation agent;
cardioprotective agent;
estrogen receptor agonist;
estrogen receptor antagonist |
| (+-)-Dihydromethysticin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| 2-[2-[2-(2-aminophenoxy)ethoxy]ethoxy]aniline | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| chondocurine (1beta)-(+-)-isomer | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-methyl-4-prop-2-enoxy-2-pyrimidinone | [no description available] | low | 0 | 0 | aromatic ether;
pyrimidone | |
| noscapine | [no description available] | low | 0 | 0 | aromatic ether;
benzylisoquinoline alkaloid;
cyclic acetal;
isobenzofuranone;
organic heterobicyclic compound;
organic heterotricyclic compound;
tertiary amino compound | antineoplastic agent;
antitussive;
apoptosis inducer;
plant metabolite |
| 4-[4-(3-methyl-4-nitrophenoxy)butoxy]benzonitrile | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| lariciresinol | [no description available] | low | 0 | 0 | aromatic ether;
lignan;
oxolanes;
phenols;
primary alcohol | antifungal agent;
plant metabolite |
| tryptoquivaline | [no description available] | low | 0 | 0 | aromatic ether;
indole alkaloid;
organic heteropentacyclic compound | breast cancer resistance protein inhibitor;
mycotoxin |
| 2-methoxyestrone | [no description available] | low | 0 | 0 | 17-oxo steroid;
3-hydroxy steroid;
alicyclic ketone;
aromatic ether;
phenolic steroid;
phenols | human metabolite;
mouse metabolite |
| win 54954 | [no description available] | low | 0 | 0 | aromatic ether | |
| silychristin | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone | lipoxygenase inhibitor;
metabolite;
prostaglandin antagonist;
radical scavenger |
| cleomiscosin a | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactone;
organic heterotricyclic compound;
phenols;
primary alcohol | anti-inflammatory agent;
metabolite |
| bispyribac | [no description available] | low | 0 | 0 | aromatic ether;
benzoic acids;
monocarboxylic acid;
pyrimidines | herbicide |
| petunidin-3-glucoside | [no description available] | low | 0 | 0 | anthocyanin cation;
aromatic ether;
beta-D-glucoside | antioxidant;
metabolite |
| malvidin-3-glucoside | [no description available] | low | 0 | 0 | anthocyanin cation;
aromatic ether;
beta-D-glucoside | metabolite |
| dioncophylline c | [no description available] | low | 0 | 0 | aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes;
naphthols | antimalarial;
antiplasmodial drug;
metabolite |
| stigmatellin | [no description available] | low | 0 | 0 | aromatic ether;
chromones;
olefinic compound;
phenols | bacterial metabolite;
quinol oxidation site inhibitor |
| roflumilast | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
chloropyridine;
cyclopropanes;
organofluorine compound | anti-asthmatic drug;
phosphodiesterase IV inhibitor |
| teniposide | [no description available] | low | 0 | 0 | aromatic ether;
beta-D-glucoside;
cyclic acetal;
furonaphthodioxole;
gamma-lactone;
monosaccharide derivative;
phenols;
thiophenes | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor |
| prinomastat | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
pyridines;
sulfonamide;
thiomorpholines | antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
matrix metalloproteinase inhibitor |
| posaconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole antifungal drug;
N-arylpiperazine;
organofluorine compound;
oxolanes;
triazole antifungal drug;
triazoles | trypanocidal drug |
| gancaonin I | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
resorcinols | antibacterial agent;
plant metabolite |
| glycyrin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins;
hydroxyisoflavans | antibacterial agent;
metabolite;
plant metabolite |
| glyasperin D | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | plant metabolite |
| licoricidin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxyisoflavans;
methoxyisoflavan | antibacterial agent;
plant metabolite |
| egonol | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
benzodioxoles;
primary alcohol | plant metabolite |
| N-ethylharmine | [no description available] | low | 0 | 0 | aromatic ether;
beta-carbolines;
semisynthetic derivative | anti-HIV agent |
| pf 1163a | [no description available] | low | 0 | 0 | aromatic ether;
lactam;
macrolide antibiotic;
secondary alcohol | antifungal agent;
Penicillium metabolite |
| pf 1163b | [no description available] | low | 0 | 0 | aromatic ether;
lactam;
macrolide antibiotic | antifungal agent;
Penicillium metabolite |
| licocoumarone | [no description available] | low | 0 | 0 | 1-benzofurans;
aromatic ether;
resorcinols | antibacterial agent;
apoptosis inducer;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite |
| 4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| LSM-22807 | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| piperlactam s | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
gamma-lactam;
organic heterotetracyclic compound;
phenols | anti-inflammatory agent;
antioxidant;
plant metabolite |
| 5,5-dioxo-1-(4-phenoxyphenyl)-3a,4,6,6a-tetrahydro-3H-thieno[3,4-b]pyrrol-2-one | [no description available] | low | 0 | 0 | aromatic ether | |
| antofine | [no description available] | low | 0 | 0 | alkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound | angiogenesis inhibitor;
anti-inflammatory agent;
antimicrobial agent;
antineoplastic agent;
antiviral agent;
phytotoxin;
plant metabolite |
| xanthohumol | [no description available] | low | 0 | 0 | aromatic ether;
chalcones;
polyphenol | anti-HIV-1 agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor;
metabolite |
| 2-phenoxy-N-(2-pyridinyl)butanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-amino-4-(2-ethoxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
pyranopyrazole | |
| N-[4-[4-[[1-oxo-2-(1-pyrrolidinyl)ethyl]amino]phenoxy]phenyl]-2-(1-pyrrolidinyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(3,4-diethoxyphenyl)-5-(2-furanyl)-1,3,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[5-(phenoxymethyl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(8-methyl-2,5,11,14-tetraoxa-8-azabicyclo[13.4.0]nonadeca-1(15),16,18-trien-17-yl)ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-[2-(3-phenoxypropyl)-5-tetrazolyl]pyridine | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-cyclohexyl-5-(2-phenoxyethylthio)tetrazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-amino-4-[3-ethoxy-4-[2-(4-morpholinyl)ethoxy]phenyl]-3-ethyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
pyranopyrazole | |
| 2-[[5-[(2,3-dimethylphenoxy)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-1-thiophen-2-ylethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| (1-methyl-2-imidazolyl)-(4-phenylmethoxyphenyl)methanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3-butoxyphenyl)-1,3,4-thiadiazol-2-amine | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-(2-ethoxy-6-methyl-3-pyridinyl)-5-(2-pyridinyl)-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-(3,4,5-triethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | [no description available] | low | 0 | 0 | aromatic ether;
triazolothiadiazole | |
| 4-(1-benzotriazolyl)-5-(2-methoxyphenoxy)benzene-1,2-dicarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-cyclohexyl-3-[(3-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| 7-ethoxy-9-nitro-5H-benzo[b][1,4]benzoxazepin-6-one | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[4-(2-quinoxalinyl)phenoxy]benzene-1,2-dicarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(phenoxymethyl)-4-triazolecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-ethylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(4-ethylphenoxy)methyl]-N-(2-pyridinylmethyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 7-methoxy-3,5-dimethyl-2-thiazolo[4,5-d]pyrimidinethione | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[4-(4-ethylphenyl)-2-thiazolyl]carbamic acid phenyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-bromo-4-methylphenoxy)-N-(2-pyridinylmethyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[[3-(4-chlorophenoxy)phenyl]methyl]-4-ethylpiperazine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenol | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 4-[[4-(ethylamino)-6-(methylthio)-1,3,5-triazin-2-yl]oxy]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-ethyl-3-[[4-(2-methylpropoxy)phenyl]methylthio]-1H-1,2,4-triazole | [no description available] | low | 0 | 0 | aromatic ether | |
| [4-[(2-fluorophenyl)methoxy]phenyl]-(1-pyrrolidinyl)methanethione | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(2-chlorophenoxy)methyl]-3-pyridin-4-yl-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-phenylmethoxyphenyl)thiadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-methyl-2-[[4-methyl-5-[(4-nitrophenoxy)methyl]-1,2,4-triazol-3-yl]thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-[[5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-morpholinyl)ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(3-pyridinyloxy)benzene-1,2-dicarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| N-tert-butyl-2-(4-chloro-3-methylphenoxy)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(2-furanylmethyl)-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(2-methylpropyl)-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-cyclopentyl-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(4-ethoxyphenoxy)methyl]-N-(3-pyridinyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2,3-dimethylphenoxy)-N-pyridin-4-ylacetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-[(2-chlorophenoxy)methyl]-N-(2-thiazolyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(4,5-dihydrothiazol-2-yl)-2-(2-methylphenoxy)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(2-fluorophenoxy)-1-methyl-3-nitro-1,2,4-triazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-methyl-5-(1-naphthalenyloxy)-4-nitroimidazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3,4-dimethoxyphenyl)-3-(2-methoxy-5-nitrophenyl)urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 1-cyclopentyl-3-(2-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-chloro-12-(4-methoxyphenyl)sulfonylquinoxalino[2,3-b][1,4]benzoxazine | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3-methoxy-5-nitrophenyl)-3-(4-methylphenyl)urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-(2-bromo-4-chlorophenoxy)-N-cyclohexyl-N-methylacetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-furanyl-[4-(4-phenoxyphenyl)sulfonyl-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(2-methoxyphenoxy)-N-(3-pyridinyl)benzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3-chlorophenyl)-3-(2-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[3-[2-(1-azepanyl)-4,5-dicyanophenoxy]phenyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2,5-dimethoxy-N-(4-phenoxyphenyl)benzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[[4-(dimethylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]oxy]benzoic acid methyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-5-methyl-3-phenyl-4-isoxazolecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-[[4-(2-chloro-6-nitrophenoxy)phenyl]methoxy]phenyl]ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2,2-dimethylpropanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[[4-(4-chlorophenoxy)anilino]-sulfanylidenemethyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-fluorophenoxy)-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-N-propan-2-ylbenzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-tert-butylphenoxy)-5-methoxy-2-phenylpyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-phenoxy-2-phenyl-5-pyrimidinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| Src Inhibitor-1 | [no description available] | low | 0 | 0 | aromatic ether;
polyether;
quinazolines;
secondary amino compound | EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| N-[2,5-dioxo-6-(4-phenoxyphenyl)-3-pyrano[3,2-c]pyridinyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-chlorophenoxy)-4-(dimethylamino)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-methyl-5-[2-(2-methylphenoxy)ethyl]-2-sulfanylidene-1H-pyrimidin-4-one | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-chlorophenoxy)-1-(4-morpholinyl)-1-butanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N4-ethyl-6-[2-(4-methylphenoxy)ethylthio]-N2-propan-2-yl-1,3,5-triazine-2,4-diamine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[[1-oxo-3-(4-propan-2-yloxyphenyl)propyl]amino]-3-(phenylmethyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[3-(3-methylphenoxy)-5-nitrophenyl]-2-(3-nitro-1,2,4-triazol-1-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-bis(2-fluorophenoxy)phosphoryl-3,4-dimethylaniline | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(2-ethoxyanilino)-6-(4-ethoxyanilino)-2-pyrimidinyl]methylidene]propanedinitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-methyl-3-[(4-pentoxyphenyl)methylthio]-1H-1,2,4-triazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 4,5-dichloro-1-[2-(4-chlorophenoxy)ethyl]imidazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-butyl-3-(4-phenoxyphenyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-(3-cyano-2-thiophenyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-bromophenyl)-5-[(2-chlorophenoxy)methyl]-1,3,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(4-ethoxyphenyl)-N-(3,4,5,6-tetrahydro-2H-azepin-7-yl)-1,3,4-oxadiazol-2-amine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(4-chloro-2-methylphenoxy)-1-(4-morpholinyl)-1-butanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diamine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[2-(4-chlorophenoxy)ethylthio]pyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3-phenoxypropyl)-3-(3-pyridinyl)-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(3-ethoxy-2-prop-2-enoxyphenyl)methyl]-2-thiazolamine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-bromophenoxy)-N-(2-pyridinylmethyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[2-[(4-chlorophenyl)thio]ethoxy]-3-ethoxybenzaldehyde | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3-fluorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-4H-pyridine-3,5-dicarboxylic acid diethyl ester | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 5-(2-ethoxyphenyl)-3H-1,3,4-oxadiazole-2-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| N-tert-butyl-4-(2-fluorophenoxy)-1-butanamine | [no description available] | low | 0 | 0 | aromatic ether | |
| N-butyl-4-phenoxy-1-butanamine | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-methylphenyl) ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 1,3-dimethyl-5-[[2-[2-(4-nitrophenoxy)ethoxy]phenyl]methylidene]-1,3-diazinane-2,4,6-trione | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 4-[2-[2-(4-bromo-2-chlorophenoxy)ethoxy]ethyl]morpholine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[2-(3-ethylphenoxy)ethyl]propanedioic acid diethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-[4-[4-(2-methylbutan-2-yl)phenoxy]anilino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[3-(2-bromo-4-chlorophenoxy)propyl]-4-methylpiperidine | [no description available] | low | 0 | 0 | aromatic ether | |
| N4-(2-methoxyphenyl)benzene-1,4-diamine | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| 4-(1H-benzimidazol-2-ylthio)butanoic acid [2-oxo-2-(4-phenoxyanilino)ethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-phenoxybenzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[6-amino-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-2-(2-methylphenoxy)-N-(2-methylpropyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-[[6-[(2-methyl-5-thieno[2,3-e][1,3]benzothiazolyl)oxy]-3-pyridinyl]sulfonyl]morpholine | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3-fluorophenoxy)-8-nitroisoquinoline | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-(2-prop-2-enylphenoxy)butyl]pyrrolidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2,4-dibromophenoxy)-N-[oxo-(propan-2-ylamino)methyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-phenoxyphenyl 4-hydroxypiperidine-1-carboxylate | [no description available] | low | 0 | 0 | aromatic ether | |
| N'-benzoyl-5-(3,5-dichlorophenoxy)-2-furancarbohydrazide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[2-[(4-chlorophenoxy)methyl]-4-thiazolyl]ethanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(benzyloxy)-2-(hydroxymethyl)-1,4-dihydropyridin-4-one | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-aminophenoxy)isophthalonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| N5-(2-chloro-6-phenoxybenzyl)-1H-1,2,4-triazole-3,5-diamine | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(2-chloro-6-phenoxyphenyl)methyl]benzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-(tert-butyl)-3-isoxazolyl]-N'-[2-(trifluoromethoxy)phenyl]urea | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-(4-methoxyphenoxy)-2-imidazo[1,2-b]pyridazinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-fluoro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2,4-dichloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 1-anilino-3-[4-(3-anilino-2-hydroxypropoxy)phenoxy]-2-propanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-(3-ethoxyphenoxy)butyl]imidazole | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-oxolanecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[[2-(2,4-difluorophenoxy)-1-oxopropyl]amino]-3-(2-oxolanylmethyl)thiourea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[[(5-bromo-6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2-(2-chlorophenoxy)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[(4-chlorophenyl)sulfonyl-methylamino]-N-(4-methoxy-2-nitrophenyl)acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 4-oxido-3-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(2-fluorophenyl)-3-(4-methoxy-2-nitrophenyl)urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-[[5-[(2-fluorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-N-[(2-furanylmethylamino)-oxomethyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| cyclopropanecarboxylic acid [2-oxo-2-(4-phenoxyanilino)ethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| toremifene | [no description available] | low | 0 | 0 | aromatic ether;
organochlorine compound;
tertiary amine | antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator |
| dieckol | [no description available] | low | 0 | 0 | aromatic ether;
oxacycle;
phlorotannin | anticoagulant;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
metabolite;
radical scavenger |
| 2-[(2-ethoxyphenoxy)-phenylmethyl]morpholine | [no description available] | low | 0 | 0 | aromatic ether | |
| naproxol | [no description available] | low | 0 | 0 | aromatic ether | antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| tamoxifen n-oxide | [no description available] | low | 0 | 0 | aromatic ether;
tertiary amine oxide | anti-estrogen;
metabolite |
| diafenthiuron | [no description available] | low | 0 | 0 | aromatic ether;
thiourea acaricide;
thiourea insecticide | oxidative phosphorylation inhibitor;
proinsecticide |
| ospemifene | [no description available] | low | 0 | 0 | aromatic ether;
organochlorine compound;
primary alcohol | anti-inflammatory agent;
antineoplastic agent;
estrogen receptor modulator |
| tandutinib | [no description available] | low | 0 | 0 | aromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
piperidines;
quinazolines;
tertiary amino compound | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| zd 6474 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine | antineoplastic agent;
tyrosine kinase inhibitor |
| adefovir | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
organooxygen heterocyclic antibiotic;
polyphenol | antimalarial;
Aspergillus metabolite;
marine metabolite |
| 3-chloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| N-(2-hydroxyethyl)-4-[2-nitro-4-(trifluoromethyl)phenoxy]benzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| N'-[2-[(4-amino-5-cyano-2-pyrimidinyl)thio]-1-oxoethyl]-2-(4-methylphenoxy)acetohydrazide | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(2-methyl-4-thiazolyl)methyl]-4-phenoxybenzenesulfonamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 6-amino-4-(2-ethoxy-4-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether;
pyranopyrazole | |
| 1-[(2-ethoxyphenyl)methyl]-3-thiophen-2-ylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| quinoxyfen | [no description available] | low | 0 | 0 | aromatic ether;
monofluorobenzenes;
organochlorine compound;
quinolines | antifungal agrochemical |
| nafadotride | [no description available] | low | 0 | 0 | aromatic ether;
naphthalenecarboxamide;
nitrile;
pyrrolidines;
tertiary amino compound | dopaminergic antagonist |
| 1-(1-naphthalenyl)-3-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]urea | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| 2-methyl-1,3-bis(phenylmethoxy)benzene | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-[(4-ethylphenoxy)methyl]-4-(6-methylheptan-2-yl)-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-chloro-N-(2-methyl-6-oxo-5H-benzo[b][1,4]benzoxazepin-8-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(benzenesulfonyl)-4-(2,6-dimethylphenoxy)-2-phenylpyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(2-methylphenoxy)-6-phenylfuro[2,3-d]pyrimidine | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[4-(2-chlorophenoxy)butyl]imidazole | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
monochlorobenzenes | |
| N-(2-chlorophenyl)-4-[[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]hydrazo]-4-oxobutanamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| N-(2-methoxy-4-nitrophenyl)-2-[(1-methyl-2-imidazolyl)thio]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound | |
| N-[4-(phenoxymethyl)-2-thiazolyl]-1-adamantanecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| hydroxypioglitazone | [no description available] | low | 0 | 0 | aromatic ether;
pyridines;
thiazolidinediones | human xenobiotic metabolite |
| sc 560 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles | angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug |
| sc-19220 | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-methyl-4-(3-phenoxyphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-6-carboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 8-[4-(4-fluorophenoxy)-3-nitrophenyl]-7-(2-hydroxyethyl)-3-(phenylmethyl)purine-2,6-dione | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-phenoxybenzoic acid [2-oxo-2-(propan-2-ylamino)ethyl] ester | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(4-bromophenoxy)-N'-[2-[(4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]acetohydrazide | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-(2-methoxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrile | [no description available] | low | 0 | 0 | aromatic ether;
substituted aniline | |
| N-(4-phenoxyphenyl)-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 5-(3,4-dimethoxyphenyl)-3-(2-furanylmethyl)-4-imino-5H-[1]benzopyrano[2,3-d]pyrimidin-8-ol | [no description available] | low | 0 | 0 | aromatic ether | |
| 3,3-dimethyl-1,5-dinitro-6-phenoxy-3-azoniabicyclo[3.3.1]non-6-ene | [no description available] | low | 0 | 0 | aromatic ether | |
| fraxin | [no description available] | low | 0 | 0 | aromatic ether;
beta-D-glucoside;
hydroxycoumarin | anti-inflammatory agent;
hepatoprotective agent;
plant metabolite |
| fraxetin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxycoumarin | anti-inflammatory agent;
antibacterial agent;
antimicrobial agent;
antioxidant;
apoptosis inducer;
apoptosis inhibitor;
Arabidopsis thaliana metabolite;
hepatoprotective agent;
hypoglycemic agent |
| 5,6-dehydrokawain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| jtk-303 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone | HIV-1 integrase inhibitor |
| coniferin | [no description available] | low | 0 | 0 | aromatic ether;
cinnamyl alcohol beta-D-glucoside;
monosaccharide derivative | plant metabolite |
| daphnoretin | [no description available] | low | 0 | 0 | aromatic ether;
hydroxycoumarin | antineoplastic agent;
antiviral agent;
metabolite |
| kavain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| methysticin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| yangonin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| hinokiflavone | [no description available] | low | 0 | 0 | aromatic ether;
biflavonoid;
hydroxyflavone | antineoplastic agent;
metabolite;
neuroprotective agent |
| gentiacaulein | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | plant metabolite |
| gentisin | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | plant metabolite |
| isogentisin | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite |
| mangostin | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite |
| 1,8-dihydroxy-3,7-dimethoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | plant metabolite |
| swerchirin | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | hypoglycemic agent;
metabolite |
| 1,2,8-trihydroxy-6-methoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | antioxidant;
plant metabolite |
| wedelolactone | [no description available] | low | 0 | 0 | aromatic ether;
coumestans;
delta-lactone;
polyphenol | antineoplastic agent;
apoptosis inducer;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
hepatoprotective agent;
metabolite |
| sofalcone | [no description available] | low | 0 | 0 | aromatic ether;
chalcones;
monocarboxylic acid | anti-ulcer drug;
antibacterial agent;
gastrointestinal drug;
plant metabolite |
| neticonazole | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
conazole antifungal drug;
enamine;
imidazole antifungal drug;
imidazoles;
methyl sulfide | antifungal drug;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| pibutidine | [no description available] | low | 0 | 0 | aromatic ether;
cyclobutenones;
olefinic compound;
piperidines;
primary amino compound;
pyridines;
secondary amino compound | anti-ulcer drug;
H2-receptor antagonist |
| purmorphamine | [no description available] | low | 0 | 0 | aromatic ether;
morpholines;
purines;
secondary amino compound | osteogenesis regulator;
SMO receptor agonist |
| 8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile | [no description available] | low | 0 | 0 | aromatic ether | |
| ro 41-5253 | [no description available] | low | 0 | 0 | aromatic ether;
benzoic acids;
sulfone;
thiochromane | apoptosis inducer;
retinoic acid receptor alpha antagonist |
| glycycoumarin | [no description available] | low | 0 | 0 | aromatic ether;
coumarins;
resorcinols | antispasmodic drug;
plant metabolite |
| isoginkgetin | [no description available] | low | 0 | 0 | aromatic ether;
biflavonoid | antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
plant metabolite |
| neoglycyrol | [no description available] | low | 0 | 0 | aromatic ether;
coumestans;
delta-lactone;
polyphenol | antineoplastic agent;
plant metabolite |
| rhamnazin | [no description available] | low | 0 | 0 | aromatic ether;
dimethoxyflavone;
phenols;
trihydroxyflavone | antineoplastic agent;
plant metabolite |
| bosutinib | [no description available] | low | 0 | 0 | aminoquinoline;
aromatic ether;
dichlorobenzene;
N-methylpiperazine;
nitrile;
tertiary amino compound | antineoplastic agent;
tyrosine kinase inhibitor |
| bw b70c | [no description available] | low | 0 | 0 | aromatic ether;
hydroxamic acid;
organofluorine compound;
ureas | EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor |
| lichexanthone | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | plant metabolite |
| alternariol monomethyl ether | [no description available] | low | 0 | 0 | aromatic ether;
benzochromenone | antifungal agent;
fungal metabolite;
mycotoxin |
| decussatin | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | plant metabolite |
| bedaquiline | [no description available] | low | 0 | 0 | aromatic ether;
naphthalenes;
organobromine compound;
quinolines;
tertiary alcohol;
tertiary amino compound | antitubercular agent;
ATP synthase inhibitor |
| dimethomorph | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
monochlorobenzenes;
morpholine fungicide;
tertiary carboxamide | |
| benanomicin b | [no description available] | low | 0 | 0 | aromatic ether;
disaccharide derivative;
L-alanine derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol | |
| pradimicin b | [no description available] | low | 0 | 0 | aromatic ether;
L-alanine derivative;
monosaccharide derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol | |
| 1,7-dihydroxy-4-methoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether;
phenols;
xanthones | metabolite;
plant metabolite |
| pradimicin a | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic acid;
disaccharide derivative;
L-alanine derivative;
p-quinones;
polyphenol;
pradimicin;
secondary alcohol | |
| clodinafop | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines | EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
phenoxy herbicide |
| ici 118551 | [no description available] | low | 0 | 0 | aromatic ether;
indanes;
secondary alcohol;
secondary amino compound | beta-adrenergic antagonist |
| ochnaflavone | [no description available] | low | 0 | 0 | aromatic ether;
biflavonoid;
hydroxyflavone | anti-inflammatory agent;
antiatherogenic agent;
antibacterial agent;
EC 3.1.1.4 (phospholipase A2) inhibitor;
leukotriene antagonist;
plant metabolite |
| 3-(4-fluorophenoxy)-6-methoxy-2-(4-methoxyphenyl)-1-benzothiophene 1-oxide | [no description available] | low | 0 | 0 | aromatic ether | |
| flavasperone | [no description available] | low | 0 | 0 | aromatic ether;
naphtho-gamma-pyrone;
phenols | acyl-CoA:cholesterol acyltransferase 2 inhibitor;
antiviral agent;
Aspergillus metabolite;
marine metabolite |
| 4-hydroxycordoin | [no description available] | low | 0 | 0 | aromatic ether;
chalcones;
polyphenol | anti-inflammatory agent;
antibacterial agent;
plant metabolite |
| n-feruloylserotonin | [no description available] | low | 0 | 0 | aromatic ether;
cinnamamides;
hydroxyindoles;
phenols;
secondary carboxamide | plant metabolite |
| tyrphostin ag825 | [no description available] | low | 0 | 0 | aromatic ether;
benzothiazoles;
enamide;
nitrile;
organic sulfide;
phenols;
primary carboxamide | epidermal growth factor receptor antagonist |
| 5-methoxy-3,6-diphenyl-1,2,4-triazine | [no description available] | low | 0 | 0 | aromatic ether | |
| piericidin a | [no description available] | low | 0 | 0 | aromatic ether;
methylpyridines;
monohydroxypyridine;
secondary allylic alcohol | antimicrobial agent;
bacterial metabolite;
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor;
mitochondrial respiratory-chain inhibitor |
| metrafenone | [no description available] | low | 0 | 0 | aromatic ether;
aryl phenyl ketone fungicide;
benzophenones;
organobromine compound | antifungal agrochemical |
| 2-(4-fluoro-3-(trifluoromethyl)phenoxy)-n-(phenylmethyl)butanamide | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monocarboxylic acid amide;
monofluorobenzenes | |
| b 43 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine | EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector |
| 5-(4-phenylbutoxy)psoralen | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
psoralens | geroprotector;
immunosuppressive agent;
potassium channel blocker |
| 5-ia-85380 | [no description available] | low | 0 | 0 | aromatic ether | |
| yunaconitine | [no description available] | low | 0 | 0 | acetate ester;
aromatic ether;
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound | antifeedant;
human urinary metabolite;
phytotoxin;
plant metabolite;
xenobiotic |
| ru 58668 | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
organofluorine compound;
sulfone | anti-estrogen;
antineoplastic agent;
estrogen receptor antagonist |
| altenusin | [no description available] | low | 0 | 0 | aromatic ether;
carboxybiphenyl;
catechols;
hydroxybiphenyls;
polyphenol | antifungal agent;
fungal metabolite |
| gw 501516 | [no description available] | low | 0 | 0 | 1,3-thiazoles;
aromatic ether;
aryl sulfide;
monocarboxylic acid;
organofluorine compound | carcinogenic agent;
PPARbeta/delta agonist |
| bay 58-2667 | [no description available] | low | 0 | 0 | aromatic ether;
benzoic acids;
dicarboxylic acid;
tertiary amino compound | antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent |
| camostat | [no description available] | low | 0 | 0 | aromatic ether;
phenols | |
| lenvatinib | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
cyclopropanes;
monocarboxylic acid amide;
monochlorobenzenes;
phenylureas;
quinolines | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist;
orphan drug;
vascular endothelial growth factor receptor antagonist |
| nsc 716970 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
indolecarboxamide;
organochlorine compound | antineoplastic agent |
| lobeglitazone | [no description available] | low | 0 | 0 | aromatic ether | |
| noviflumuron | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
organofluorine compound | |
| etomoxir | [no description available] | low | 0 | 0 | aromatic ether | |
| fr 148083 | [no description available] | low | 0 | 0 | aromatic ether;
macrolide;
phenols;
secondary alcohol;
secondary alpha-hydroxy ketone | antibacterial agent;
antineoplastic agent;
metabolite;
NF-kappaB inhibitor |
| 9-methoxycanthin-6-one | [no description available] | low | 0 | 0 | aromatic ether;
indole alkaloid;
organic heterotetracyclic compound | antineoplastic agent;
antiplasmodial drug;
metabolite |
| sb 3ct compound | [no description available] | low | 0 | 0 | aromatic ether | |
| varespladib methyl | [no description available] | low | 0 | 0 | aromatic ether;
benzenes;
indoles;
methyl ester;
primary carboxamide | anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor;
prodrug |
| dapagliflozin | [no description available] | low | 0 | 0 | aromatic ether;
C-glycosyl compound;
monochlorobenzenes | hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor |
| naveglitazar | [no description available] | low | 0 | 0 | aromatic ether | |
| tivozanib | [no description available] | low | 0 | 0 | aromatic ether | |
| zm 447439 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
morpholines;
polyether;
quinazolines;
secondary amino compound;
tertiary amino compound | antineoplastic agent;
apoptosis inducer;
Aurora kinase inhibitor |
| ustiloxin b | [no description available] | low | 0 | 0 | aromatic ether;
heterodetic cyclic peptide;
macrocycle;
phenols;
secondary alcohol;
secondary carboxamide;
sulfoxide | Aspergillus metabolite;
microtubule-destabilising agent;
mycotoxin |
| hypothemycin | [no description available] | low | 0 | 0 | aromatic ether;
diol;
enone;
epoxide;
macrolide;
phenols;
polyketide;
secondary alpha-hydroxy ketone | antifungal agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
fungal metabolite |
| tryprostatin a | [no description available] | low | 0 | 0 | aromatic ether;
dipeptide;
indole alkaloid;
indoles;
pyrrolopyrazine | breast cancer resistance protein inhibitor |
| cediranib | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-iodothyronamine | [no description available] | low | 0 | 0 | aromatic ether | |
| n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride | [no description available] | low | 0 | 0 | aromatic ether;
hydrochloride;
methoxybenzenes;
tertiary amino compound | antipsychotic agent;
receptor modulator |
| rubraxanthone | [no description available] | low | 0 | 0 | aromatic ether;
polyphenol;
xanthones | antibacterial agent;
antineoplastic agent;
metabolite |
| 7,8-Dihydroyangonin | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| sch 51344 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
primary alcohol;
pyrazoloquinoline;
secondary amino compound | antineoplastic agent |
| ancistroealaine a | [no description available] | low | 0 | 0 | aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes | antileishmanial agent;
antiplasmodial drug;
metabolite;
trypanocidal drug |
| pimavanserin | [no description available] | low | 0 | 0 | aromatic ether;
monofluorobenzenes;
piperidines;
tertiary amino compound;
ureas | 5-hydroxytryptamine 2A receptor inverse agonist;
antipsychotic agent;
serotonergic antagonist |
| SIS3 free base | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
isoquinolines;
monocarboxylic acid amide;
pyrrolopyridine;
tertiary carboxamide | Smad3 inhibitor |
| apixaban | [no description available] | low | 0 | 0 | aromatic ether;
lactam;
piperidones;
pyrazolopyridine | anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor |
| bibw 2992 | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
furans;
monochlorobenzenes;
organofluorine compound;
quinazolines;
secondary carboxamide;
tertiary amino compound | antineoplastic agent;
tyrosine kinase inhibitor |
| dihydrokavain | [no description available] | low | 0 | 0 | 2-pyranones;
aromatic ether | |
| troglitazone sulfate | [no description available] | low | 0 | 0 | aromatic ether;
thiazolidinone | |
| arisugacin | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactone;
enone;
organic heterotetracyclic compound;
tertiary alcohol | antimicrobial agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
Penicillium metabolite |
| saracatinib | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxoles;
diether;
N-methylpiperazine;
organochlorine compound;
oxanes;
quinazolines;
secondary amino compound | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
radiosensitizing agent |
| fonsecinone a | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol | antibacterial agent;
Aspergillus metabolite |
| crenolanib | [no description available] | low | 0 | 0 | aminopiperidine;
aromatic ether;
benzimidazoles;
oxetanes;
quinolines;
tertiary amino compound | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| aiphanol | [no description available] | low | 0 | 0 | aromatic ether;
benzodioxine;
lignan;
stilbenoid | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor |
| nigerloxin | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
benzoic acids;
phenols;
styrenes | antioxidant;
Aspergillus metabolite;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
radical scavenger |
| msdc-0160 | [no description available] | low | 0 | 0 | aromatic ether | |
| dihydroxanthohumol | [no description available] | low | 0 | 0 | aromatic ether;
dihydrochalcones;
polyphenol | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite |
| PB28 | [no description available] | low | 0 | 0 | aromatic ether;
piperazines;
tetralins | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
sigma-2 receptor agonist |
| 7-phloroeckol | [no description available] | low | 0 | 0 | aromatic ether;
phlorotannin | antioxidant;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
metabolite |
| 3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside | [no description available] | low | 0 | 0 | aromatic ether;
benzyl alcohols;
beta-D-glucoside;
monosaccharide derivative;
primary alcohol | antineoplastic agent;
metabolite |
| PDGF receptor tyrosine kinase inhibitor III | [no description available] | low | 0 | 0 | aromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
quinazolines;
tertiary amino compound | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| fluoxastrobin | [no description available] | low | 0 | 0 | aromatic ether;
dioxazine;
monochlorobenzenes;
organofluorine compound;
oxime O-ether;
pyrimidines;
strobilurin antifungal agent | antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor |
| flumorph | [no description available] | low | 0 | 0 | aromatic ether;
enamide;
morpholines;
organofluorine compound;
tertiary carboxamide | |
| regorafenib | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
phenylureas;
pyridinecarboxamide | antineoplastic agent;
hepatotoxic agent;
tyrosine kinase inhibitor |
| erastin | [no description available] | low | 0 | 0 | aromatic ether;
diether;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
quinazolines;
tertiary carboxamide | antineoplastic agent;
ferroptosis inducer;
voltage-dependent anion channel inhibitor |
| brivanib | [no description available] | low | 0 | 0 | aromatic ether;
diether;
fluoroindole;
pyrrolotriazine;
secondary alcohol | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
drug metabolite;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist |
| fg-4592 | [no description available] | low | 0 | 0 | aromatic ether;
isoquinolines;
N-acylglycine | EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor |
| picoxystrobin | [no description available] | low | 0 | 0 | aromatic ether;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
organofluorine compound;
pyridines | antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor |
| cenicriviroc | [no description available] | low | 0 | 0 | aromatic ether;
benzazocine;
diether;
imidazoles;
secondary carboxamide;
sulfoxide | anti-HIV agent;
anti-inflammatory agent;
antirheumatic drug;
chemokine receptor 2 antagonist;
chemokine receptor 5 antagonist |
| mandipropamid | [no description available] | low | 0 | 0 | aromatic ether;
monocarboxylic acid amide;
monochlorobenzenes;
terminal acetylenic compound | |
| glyceryl ferulate | [no description available] | low | 0 | 0 | 1-monoglyceride;
aromatic ether;
enoate ester;
phenols | antioxidant;
plant metabolite;
ultraviolet filter |
| ki 8751 | [no description available] | low | 0 | 0 | aromatic ether | |
| ceratamine a | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
cyclic ketone;
organic heterobicyclic compound;
organobromine compound;
secondary amino compound;
tertiary amine | antimitotic;
metabolite |
| azd 8931 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
tertiary amino compound | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist |
| bay94 9172 | [no description available] | low | 0 | 0 | (18)F radiopharmaceutical;
aromatic ether;
polyether;
secondary amino compound;
stilbenoid;
substituted aniline | radioactive imaging agent |
| olodaterol | [no description available] | low | 0 | 0 | aromatic ether;
benzoxazine;
phenols;
secondary alcohol;
secondary amino compound | beta-adrenergic agonist;
bronchodilator agent |
| dorsomorphin | [no description available] | low | 0 | 0 | aromatic ether;
piperidines;
pyrazolopyrimidine;
pyridines | bone morphogenetic protein receptor antagonist;
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor |
| cj-042794 | [no description available] | low | 0 | 0 | aromatic ether | |
| hu 308 | [no description available] | low | 0 | 0 | aromatic ether;
bridged compound;
carbobicyclic compound;
primary allylic alcohol;
synthetic cannabinoid | anti-inflammatory agent;
antihypertensive agent;
apoptosis inhibitor;
bone density conservation agent;
CB2 receptor agonist |
| ki11502 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
quinolines;
thioureas | antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| apremilast | [no description available] | low | 0 | 0 | aromatic ether;
N-acetylarylamine;
phthalimides;
sulfone | non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor |
| PF-00835231 | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxamide;
L-leucine derivative;
primary alcohol;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
drug metabolite;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
dichlorobenzene;
organofluorine compound;
pyrazolylpiperidine;
racemate | antineoplastic agent;
biomarker;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| chir-265 | [no description available] | low | 0 | 0 | aromatic ether | |
| aminocandin | [no description available] | low | 0 | 0 | aromatic ether;
echinocandin;
homodetic cyclic peptide | antiinfective agent |
| zk 756326 | [no description available] | low | 0 | 0 | aromatic ether | |
| bay 60-6583 | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
aryl sulfide;
cyanopyridine;
cyclopropanes;
monocarboxylic acid amide | adenosine A2B receptor agonist;
anti-inflammatory agent;
cardioprotective agent |
| empagliflozin | [no description available] | low | 0 | 0 | aromatic ether;
C-glycosyl compound;
monochlorobenzenes;
tetrahydrofuryl ether | hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor |
| 4-[5-(4-ethoxyphenyl)-3-isoxazolyl]-N-[(4-methylphenyl)methyl]butanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| bgt226 | [no description available] | low | 0 | 0 | aromatic ether;
imidazoquinoline;
N-arylpiperazine;
organofluorine compound;
pyridines | antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor |
| n-desmethylrosiglitazone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(5-methyl-3-nitro-1-pyrazolyl)-N-[3-(4-methylphenoxy)-5-nitrophenyl]butanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| verruculogen | [no description available] | low | 0 | 0 | aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide | Aspergillus metabolite;
GABA modulator;
mycotoxin;
Penicillium metabolite;
potassium channel blocker |
| 1-O-feruloyl-beta-D-glucose | [no description available] | low | 0 | 0 | aromatic ether;
beta-D-glucoside;
cinnamate ester;
phenols | antioxidant;
plant metabolite |
| 2,2',4,5'-tetrabromodiphenyl ether | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| hexabromodiphenyl ether 154 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| bde 183 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound | |
| l-798106 | [no description available] | low | 0 | 0 | aromatic ether;
bromobenzenes;
N-sulfonylcarboxamide | prostaglandin receptor antagonist |
| aflatoxin m1 | [no description available] | low | 0 | 0 | aflatoxin;
aromatic ether;
aromatic ketone;
tertiary alcohol | Aspergillus metabolite;
human xenobiotic metabolite;
mammalian metabolite |
| macitentan | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound;
pyrimidines;
ring assembly;
sulfamides | antihypertensive agent;
endothelin receptor antagonist;
orphan drug |
| CDN1163 | [no description available] | low | 0 | 0 | aromatic ether;
quinolines;
secondary carboxamide | SERCA activator |
| e 7050 | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(5-chloro-2-thiophenyl)methyl]-5-[(2,6-difluorophenoxy)methyl]-3-isoxazolecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| dafadine C | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
difluorobenzene;
isoxazoles;
N-acylpiperidine;
pyridines | P450 inhibitor |
| dafadine B | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
monochlorobenzenes;
monofluorobenzenes;
N-acylpiperidine;
pyridines | P450 inhibitor |
| 3-[5-(5-methyl-2-thiophenyl)-1,3,4-oxadiazol-2-yl]-N-[2-(3-pyridinyloxy)propyl]propanamide | [no description available] | low | 0 | 0 | aromatic ether | |
| violaceol II | [no description available] | low | 0 | 0 | aromatic ether;
catechols;
resorcinols | mycotoxin |
| pamapimod | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
difluorobenzene;
diol;
primary alcohol;
pyridopyrimidine;
secondary amino compound | antirheumatic drug;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| gsk690693 | [no description available] | low | 0 | 0 | 1,2,5-oxadiazole;
acetylenic compound;
aromatic amine;
aromatic ether;
imidazopyridine;
piperidines;
primary amino compound;
tertiary alcohol | antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| cnf 2024 | [no description available] | low | 0 | 0 | 2-aminopurines;
aromatic ether;
organochlorine compound;
pyridines | antineoplastic agent;
Hsp90 inhibitor |
| uk 453,061 | [no description available] | low | 0 | 0 | aromatic ether | |
| 8-{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl}-5,7-dimethoxy-4-pentyl-2H-chromen-2-one | [no description available] | low | 0 | 0 | aromatic ether;
coumarins;
pyrrolidines;
tertiary amino compound | |
| zm323881 | [no description available] | low | 0 | 0 | aromatic ether;
benzyl ether;
fluorophenol;
halophenol;
monofluorobenzenes;
organic cation;
quinazolines;
secondary amino compound;
substituted aniline | vascular endothelial growth factor receptor antagonist |
| compound w | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-[2-[(2-methylpropan-2-yl)oxy]anilino]-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| interiotherin b | [no description available] | low | 0 | 0 | aromatic ether;
fatty acid ester;
lignan;
organic heteropentacyclic compound;
oxacycle | anti-HIV agent;
metabolite |
| 5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one | [no description available] | low | 0 | 0 | aromatic ether;
homoisoflavonoid;
polyphenol | angiogenesis modulating agent;
plant metabolite |
| ph 797804 | [no description available] | low | 0 | 0 | aromatic ether;
benzamides;
organobromine compound;
organofluorine compound;
pyridone | anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| diorcinol | [no description available] | low | 0 | 0 | aromatic ether;
phenols | fungal metabolite;
marine metabolite;
metabolite |
| 2-[[4-(2-phenoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(1-pyrrolidinyl)-6-[2-(trifluoromethoxy)anilino]-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(5-chloro-2-ethoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| 2-[[4-(5-chloro-2-propan-2-yloxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol | [no description available] | low | 0 | 0 | aromatic ether | |
| mk 5108 | [no description available] | low | 0 | 0 | aromatic ether | |
| lde225 | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
benzamides;
biphenyls;
morpholines;
organofluorine compound;
tertiary amino compound | antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist |
| 1-azepanyl-[5-[(4-chloro-3,5-dimethylphenoxy)methyl]-3-isoxazolyl]methanone | [no description available] | low | 0 | 0 | aromatic ether | |
| 4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines | geroprotector;
P450 inhibitor |
| dafadine D | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
organofluorine compound;
pyridines | P450 inhibitor |
| 1-[(1-ethyl-3-methyl-4-pyrazolyl)methyl]-N-[4-(2-fluorophenoxy)phenyl]-4-piperidinecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| dafadine O | [no description available] | low | 0 | 0 | aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines;
ring assembly | P450 inhibitor |
| 5-[(3,4-dimethylphenoxy)methyl]-N-methyl-N-(4-oxanylmethyl)-3-isoxazolecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| pci 32765 | [no description available] | low | 0 | 0 | acrylamides;
aromatic amine;
aromatic ether;
N-acylpiperidine;
pyrazolopyrimidine;
tertiary carboxamide | antineoplastic agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| florbetapir f 18 | [no description available] | low | 0 | 0 | (18)F radiopharmaceutical;
aromatic ether;
organofluorine compound;
pyridines;
substituted aniline | radioactive imaging agent |
| AMG-208 | [no description available] | low | 0 | 0 | aromatic ether;
quinolines;
triazolopyridazine | antineoplastic agent;
c-Met tyrosine kinase inhibitor |
| 6-methoxyspirotryprostatin b | [no description available] | low | 0 | 0 | aromatic ether;
azaspiro compound;
indole alkaloid;
indolones | antineoplastic agent;
Aspergillus metabolite |
| lucitanib | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
naphthalenecarboxamide;
primary amino compound;
quinolines | antineoplastic agent;
fibroblast growth factor receptor antagonist;
vascular endothelial growth factor receptor antagonist |
| act-132577 | [no description available] | low | 0 | 0 | aromatic ether;
organobromine compound;
pyrimidines;
sulfamides | antihypertensive agent;
drug metabolite;
endothelin receptor antagonist;
xenobiotic metabolite |
| cabozantinib | [no description available] | low | 0 | 0 | aromatic ether;
dicarboxylic acid diamide;
organofluorine compound;
quinolines | antineoplastic agent;
tyrosine kinase inhibitor |
| poziotinib | [no description available] | low | 0 | 0 | acrylamides;
aromatic ether;
dichlorobenzene;
diether;
monofluorobenzenes;
N-acylpiperidine;
quinazolines;
secondary amino compound;
substituted aniline | antineoplastic agent;
apoptosis inducer;
epidermal growth factor receptor antagonist |
| gsk 2126458 | [no description available] | low | 0 | 0 | aromatic ether;
difluorobenzene;
pyridazines;
pyridines;
quinolines;
sulfonamide | anticoronaviral agent;
antineoplastic agent;
autophagy inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor;
radiosensitizing agent |
| gsk 1363089 | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-propan-2-ylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-3-propan-2-ylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-cyclohexyl-1-[[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| 3-cyclohexyl-1-[[(2S,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-10-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea | [no description available] | low | 0 | 0 | aromatic ether | |
| N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenoxyphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-pyridinecarboxamide | [no description available] | low | 0 | 0 | aromatic ether | |
| 1-(3,5-dimethyl-4-isoxazolyl)-3-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]urea | [no description available] | low | 0 | 0 | aromatic ether | |
| monepantel | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
aryl sulfide;
nitrile;
secondary carboxamide | anthelminthic drug;
nematicide |
| an2728 | [no description available] | low | 0 | 0 | aromatic ether;
benzoxaborole;
nitrile | antipsoriatic;
non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor |
| grazoprevir | [no description available] | low | 0 | 0 | aromatic ether;
azamacrocycle;
carbamate ester;
cyclopropanes;
lactam;
N-sulfonylcarboxamide;
quinoxaline derivative | antiviral drug;
hepatitis C protease inhibitor;
hepatoprotective agent |
| hordatine a | [no description available] | low | 0 | 0 | aromatic ether;
benzofurans;
dicarboxylic acid diamide;
guanidines;
phenols | adrenergic antagonist;
metabolite |
| 5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinone | [no description available] | low | 0 | 0 | aromatic ether | |
| tak-632 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
benzothiazoles;
cyclopropylcarboxamide;
monofluorobenzenes;
nitrile;
secondary carboxamide | antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
necroptosis inhibitor |
| lrrk2-in1 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
N-acylpiperidine;
N-alkylpiperazine;
pyrimidobenzodiazepine;
secondary amino compound;
tertiary amino compound | antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| quinolobactin | [no description available] | low | 0 | 0 | aromatic ether;
monohydroxyquinoline;
phenols;
quinolinemonocarboxylic acid | bacterial metabolite;
siderophore |
| AZD1979 | [no description available] | low | 0 | 0 | aromatic ether;
azaspiro compound;
carboxamide;
N-acylazetidine;
oxadiazole;
oxaspiro compound;
oxetanes | melanin-concentrating hormone receptor antagonist |
| ML240 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
benzimidazoles;
primary amino compound;
quinazolines;
secondary amino compound | antineoplastic agent |
| aripiprazole lauroxil | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactam;
dichlorobenzene;
dodecanoate ester;
N-alkylpiperazine;
N-arylpiperazine;
quinolone | H1-receptor antagonist;
prodrug;
second generation antipsychotic;
serotonergic agonist |
| abt-199 | [no description available] | low | 0 | 0 | aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine | antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor |
| xl765 | [no description available] | low | 0 | 0 | aromatic amine;
aromatic ether;
benzamides;
quinoxaline derivative;
sulfonamide | antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor |
| DMH1 | [no description available] | low | 0 | 0 | aromatic ether;
pyrazolopyrimidine;
quinolines | antineoplastic agent;
bone morphogenetic protein receptor antagonist;
protein kinase inhibitor |
| 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide | [no description available] | low | 0 | 0 | aromatic ether;
methylpyridines;
olefinic compound;
quinazolines;
secondary amino compound;
secondary carboxamide;
toluenes | |
| pf 4800567 | [no description available] | low | 0 | 0 | aromatic ether;
monochlorobenzenes;
oxanes;
pyrazolopyrimidine | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| propenylphosphonic acid | [no description available] | low | 0 | 0 | aromatic ether | |
| abt-333 | [no description available] | low | 0 | 0 | aromatic ether;
naphthalenes;
pyrimidone;
sulfonamide | antiviral drug;
nonnucleoside hepatitis C virus polymerase inhibitor |
| naloxegol | [no description available] | low | 0 | 0 | aromatic ether;
organic heteropentacyclic compound;
phenols;
polyether;
tertiary alcohol | cathartic;
mu-opioid receptor antagonist |
| ceritinib | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
organochlorine compound;
piperidines;
secondary amino compound;
sulfone | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| MK-8353 | [no description available] | low | 0 | 0 | aromatic ether;
dihydropyridine;
indazoles;
methyl sulfide;
N-alkylpyrrolidine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
triazoles | antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| HG-10-102-01 | [no description available] | low | 0 | 0 | aminopyrimidine;
aromatic ether;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
secondary amino compound | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| N-[(5-methyl-2-furanyl)methylideneamino]-2-phenoxybenzamide | [no description available] | low | 0 | 0 | aromatic ether | |
| saroglitazar | [no description available] | low | 0 | 0 | aromatic ether;
methyl sulfide;
monocarboxylic acid;
pyrroles | hypoglycemic agent;
PPARalpha agonist;
PPARgamma agonist |
| fertaric acid | [no description available] | low | 0 | 0 | aromatic ether;
cinnamate ester;
dicarboxylic acid;
phenols;
tetraric acid derivative | |
| 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
tertiary alcohol;
triazoles | |
| pf-06463922 | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
azamacrocycle;
benzamides;
cyclic ether;
monofluorobenzenes;
nitrile;
organic heterotetracyclic compound;
pyrazoles | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| DDR1-IN-1 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
benzamides;
N-alkylpiperazine;
oxindoles;
secondary carboxamide | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| ldc4297 | [no description available] | low | 0 | 0 | aromatic ether;
piperidines;
pyrazoles;
pyrazolotriazine;
secondary amino compound | antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor |
| MLI-2 | [no description available] | low | 0 | 0 | aromatic ether;
cyclopropanes;
indazoles;
morpholines;
pyrimidines;
tertiary amino compound | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| ap20187 | [no description available] | low | 0 | 0 | aromatic ether;
carboxylic ester;
N-acylpiperidine;
tertiary amino compound | ligand |
| biliatresone | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
benzodioxoles;
enone;
phenols | plant metabolite;
toxin |
| tak 491 | [no description available] | low | 0 | 0 | 1,2,4-oxadiazole;
aromatic ether;
benzimidazoles;
carboxylic ester;
cyclic carbonate ester;
dioxolane | angiotensin receptor antagonist;
antihypertensive agent;
prodrug |
| azilsartan | [no description available] | low | 0 | 0 | 1,2,4-oxadiazole;
aromatic ether;
benzimidazolecarboxylic acid | angiotensin receptor antagonist;
antihypertensive agent |
| hydrazinocurcumin | [no description available] | low | 0 | 0 | aromatic ether;
olefinic compound;
polyphenol;
pyrazoles | angiogenesis modulating agent;
antineoplastic agent;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| mirodenafil | [no description available] | low | 0 | 0 | aromatic ether;
N-alkylpiperazine;
primary alcohol;
pyrrolopyrimidine;
sulfonamide | EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent |
| cerulomycin | [no description available] | low | 0 | 0 | aldoxime;
aromatic ether;
bipyridines;
pyridine alkaloid | antineoplastic agent;
bacterial metabolite;
marine metabolite |
| undecylprodigiosin | [no description available] | low | 0 | 0 | alkaloid;
aromatic ether;
tripyrrole | antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent |
| sb-590885 | [no description available] | low | 0 | 0 | aromatic ether;
imidazoles;
ketoxime;
pyridines;
tertiary amino compound | |
| 2-[[4-(trifluoromethoxy)phenyl]methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one | [no description available] | low | 0 | 0 | aromatic ether | |
| PF-07304814 | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxamide;
L-leucine derivative;
phosphate monoester;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
prodrug |
| 3-cyanopyridine | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 4-phenyl-3-furoxancarbonitrile | [no description available] | low | 0 | 0 | 1,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile | geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent |
| anastrozole | [no description available] | low | 0 | 0 | nitrile;
triazoles | antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor |
| bicalutamide | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
monocarboxylic acid amide;
monofluorobenzenes;
nitrile;
sulfone;
tertiary alcohol | |
| carbonyl cyanide m-chlorophenyl hydrazone | [no description available] | low | 0 | 0 | hydrazone;
monochlorobenzenes;
nitrile | antibacterial agent;
geroprotector;
ionophore |
| cimaterol | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| cimetidine | [no description available] | low | 0 | 0 | aliphatic sulfide;
guanidines;
imidazoles;
nitrile | adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor |
| citalopram | [no description available] | low | 0 | 0 | 2-benzofurans;
cyclic ether;
nitrile;
organofluorine compound;
tertiary amino compound | |
| milrinone | [no description available] | low | 0 | 0 | bipyridines;
nitrile;
pyridone | cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent |
| nilvadipine | [no description available] | low | 0 | 0 | dihydropyridine;
isopropyl ester;
methyl ester;
nitrile | |
| periciazine | [no description available] | low | 0 | 0 | hydroxypiperidine;
nitrile;
phenothiazines | adrenergic antagonist;
first generation antipsychotic;
sedative |
| zaleplon | [no description available] | low | 0 | 0 | nitrile;
pyrazolopyrimidine | anticonvulsant;
anxiolytic drug;
central nervous system depressant;
sedative |
| systhane | [no description available] | low | 0 | 0 | monochlorobenzenes;
nitrile;
triazoles | |
| benzonitrile | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| chloroacetonitrile | [no description available] | low | 0 | 0 | nitrile | |
| benzyl cyanide | [no description available] | low | 0 | 0 | benzenes;
nitrile | animal metabolite;
pheromone |
| pirinitramide | [no description available] | low | 0 | 0 | nitrile | |
| cyanamide | [no description available] | low | 0 | 0 | nitrile;
one-carbon compound | EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor |
| dicyandiamido | [no description available] | low | 0 | 0 | guanidines;
nitrile | curing agent;
explosive;
fertilizer;
flame retardant;
nitrification inhibitor |
| ricinine | [no description available] | low | 0 | 0 | nitrile;
pyridine alkaloid;
pyridone | |
| toyocamycin | [no description available] | low | 0 | 0 | antibiotic antifungal agent;
N-glycosylpyrrolopyrimidine;
nitrile;
ribonucleoside | antimetabolite;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite |
| 2-cyanophenol | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| 1,3-dicyanobenzene | [no description available] | low | 0 | 0 | nitrile | |
| diphenoxylate | [no description available] | low | 0 | 0 | ethyl ester;
nitrile;
piperidinecarboxylate ester;
tertiary amine | antidiarrhoeal drug |
| ioxynil | [no description available] | low | 0 | 0 | iodophenol;
nitrile | environmental contaminant;
herbicide;
xenobiotic |
| enbucrilate | [no description available] | low | 0 | 0 | alpha,beta-unsaturated monocarboxylic acid;
nitrile | |
| cyanophenphos | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| difenoxin | [no description available] | low | 0 | 0 | nitrile;
piperidinemonocarboxylic acid;
tertiary amine | antidiarrhoeal drug |
| closantel | [no description available] | low | 0 | 0 | aromatic amide;
monocarboxylic acid amide;
monochlorobenzenes;
nitrile;
organoiodine compound;
phenols | |
| bezitramide | [no description available] | low | 0 | 0 | nitrile | |
| cyanopyrazine | [no description available] | low | 0 | 0 | nitrile;
pyrazines | |
| tetracyanoquinodimethane | [no description available] | low | 0 | 0 | alicyclic compound;
nitrile;
quinodimethane | |
| fludioxonil | [no description available] | low | 0 | 0 | benzodioxoles;
nitrile;
organofluorine compound;
pyrroles | androgen antagonist;
antifungal agrochemical;
estrogen receptor agonist |
| fenpiclonil | [no description available] | low | 0 | 0 | dichlorobenzene;
nitrile;
pyrroles | antifungal agrochemical |
| 2-(3,4-dimethoxyphenyl)-5-amino-2-isopropylvaleronitrile | [no description available] | low | 0 | 0 | dimethoxybenzene;
nitrile;
secondary amino compound | drug metabolite;
marine xenobiotic metabolite |
| 2,3-bis(4-hydroxyphenyl)-propionitrile | [no description available] | low | 0 | 0 | nitrile;
phenols | estrogen receptor agonist |
| taxiphyllin | [no description available] | low | 0 | 0 | beta-D-glucoside;
nitrile | |
| 3,4-epithiobutanenitrile | [no description available] | low | 0 | 0 | epithionitrile;
nitrile;
thiirane | |
| cyc 682 | [no description available] | low | 0 | 0 | nitrile;
nucleoside analogue;
secondary carboxamide | antimetabolite;
antineoplastic agent;
DNA synthesis inhibitor;
prodrug |
| dhurrin | [no description available] | low | 0 | 0 | beta-D-glucoside;
cyanogenic glycoside;
monosaccharide derivative;
nitrile | |
| 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrile | [no description available] | low | 0 | 0 | monochlorobenzenes;
nitrile;
organobromine compound;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide;
pyrroles | acaricide;
antifouling biocide;
insecticide |
| 2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| l 778,123 | [no description available] | low | 0 | 0 | imidazoles;
monochlorobenzenes;
nitrile;
piperazinone;
tertiary amino compound | antineoplastic agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor |
| 6-methyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| indole-3-acetonitrile | [no description available] | low | 0 | 0 | indoles;
nitrile | auxin;
human xenobiotic metabolite;
plant hormone;
plant metabolite |
| Girgensonine | [no description available] | low | 0 | 0 | nitrile | |
| bms 214662 | [no description available] | low | 0 | 0 | benzenes;
benzodiazepine;
imidazoles;
nitrile;
sulfonamide;
thiophenes | antineoplastic agent;
apoptosis inducer;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor |
| diclazuril | [no description available] | low | 0 | 0 | nitrile | |
| ravuconazole | [no description available] | low | 0 | 0 | 1,3-thiazoles;
fluorobenzenes;
nitrile;
tertiary alcohol;
triazoles | antifungal drug;
antileishmanial agent;
EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor;
ergosterol biosynthesis inhibitor |
| mesoxalonitrile | [no description available] | low | 0 | 0 | alpha-ketonitrile;
nitrile | |
| 3-[di(propan-2-yl)phosphorylmethyl]benzonitrile | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| crotononitrile | [no description available] | low | 0 | 0 | nitrile | |
| 2,6-diamino-4-(1-phenylethyl)-4H-thiopyran-3,5-dicarbonitrile | [no description available] | low | 0 | 0 | nitrile;
organosulfur heterocyclic compound | |
| 6-hydroxy-1-(3-hydroxypropyl)-4-methyl-2-oxo-5-(1-piperidinylmethyl)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| trilostane | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
3-hydroxy steroid;
androstanoid;
epoxy steroid;
nitrile | abortifacient;
antineoplastic agent;
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor |
| 5-ethyl-4,6-dimethyl-2-sulfanylidene-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 6-amino-3-(methoxymethyl)-5-spiro[2H-pyrano[2,3-c]pyrazole-4,4'-thiane]carbonitrile | [no description available] | low | 0 | 0 | nitrile;
organic sulfide;
organosulfur heterocyclic compound;
oxaspiro compound | |
| iFSP1 | [no description available] | low | 0 | 0 | aromatic amine;
nitrile;
primary amino compound;
pyridobenzimidazole;
toluenes | antineoplastic agent;
ferroptosis inducer;
ferroptosis suppressor protein 1 inhibitor |
| 4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| 2-amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 4-(methoxymethyl)-6-methyl-2-(2-methylanilino)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone | [no description available] | low | 0 | 0 | bromophenol;
nitrile;
pyridone | |
| 4-(1H-imidazol-1-ylmethyl)benzonitrile | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| 6-amino-1-(4-chlorophenyl)-2-oxo-4-(1,2,4-triazol-1-ylmethyl)-5-pyrimidinecarbonitrile | [no description available] | low | 0 | 0 | monochlorobenzenes;
nitrile;
pyrimidone;
triazoles | |
| 6-tert-butyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 4,6-dimethyl-2-[3-(4-morpholinyl)propylamino]-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 2-(methylamino)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 2-(1-piperidinyl)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 2-(4-fluorophenyl)-2-[4-[(4-fluorophenyl)-oxomethyl]phenyl]acetonitrile | [no description available] | low | 0 | 0 | nitrile | |
| 5-Chloro-2-hydroxy-4,6-dimethylnicotinonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 2-oxo-4,6-dithiophen-2-yl-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| 2-[(4-chlorophenyl)methoxy]-6-methoxybenzonitrile | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| 4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrile | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| or 1259 | [no description available] | low | 0 | 0 | hydrazone;
nitrile;
pyridazinone | anti-arrhythmia drug;
cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
vasodilator agent |
| fipronil sulfone | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
dichlorobenzene;
nitrile;
pyrazoles;
sulfone | marine xenobiotic metabolite |
| 4-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]benzonitrile | [no description available] | low | 0 | 0 | biphenyls;
nitrile | |
| entacapone | [no description available] | low | 0 | 0 | 2-nitrophenols;
catechols;
monocarboxylic acid amide;
nitrile | antidyskinesia agent;
antiparkinson drug;
central nervous system drug;
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor |
| 2-[3-(diethylamino)propylamino]-4-(methoxymethyl)-6-methyl-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile;
pyridines | |
| ag-490 | [no description available] | low | 0 | 0 | catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide | anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor |
| alpha-cyano-4-hydroxycinnamic acid | [no description available] | low | 0 | 0 | monohydroxycinnamic acid;
nitrile;
phenols | MALDI matrix material |
| bay 11-7082 | [no description available] | low | 0 | 0 | nitrile;
sulfone | apoptosis inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
non-steroidal anti-inflammatory drug;
platelet aggregation inhibitor |
| bay 11-7085 | [no description available] | low | 0 | 0 | benzenes;
nitrile;
sulfone | anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor |
| su 1498 | [no description available] | low | 0 | 0 | enamide;
monocarboxylic acid amide;
nitrile;
phenols;
secondary carboxamide | vascular endothelial growth factor receptor antagonist |
| alpha-(p-Methoxyphenyl)-2-pyridineacrylonitrile | [no description available] | low | 0 | 0 | nitrile | |
| ekb 569 | [no description available] | low | 0 | 0 | aminoquinoline;
monocarboxylic acid amide;
monochlorobenzenes;
nitrile | protein kinase inhibitor |
| rilpivirine | [no description available] | low | 0 | 0 | aminopyrimidine;
nitrile | EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor |
| vilazodone | [no description available] | low | 0 | 0 | 1-benzofurans;
indoles;
monocarboxylic acid amide;
N-alkylpiperazine;
N-arylpiperazine;
nitrile | antidepressant;
serotonergic agonist;
serotonin uptake inhibitor |
| isavuconazole | [no description available] | low | 0 | 0 | 1,3-thiazoles;
conazole antifungal drug;
difluorobenzene;
nitrile;
tertiary alcohol;
triazole antifungal drug | EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
ergosterol biosynthesis inhibitor;
orphan drug |
| flonicamid | [no description available] | low | 0 | 0 | nitrile;
organofluorine compound;
pyridinecarboxamide | environmental contaminant;
insecticide;
xenobiotic |
| cyazofamid | [no description available] | low | 0 | 0 | imidazole fungicide;
imidazoles;
nitrile;
organochlorine compound;
sulfamides;
sulfonamide fungicide | antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor |
| hki 272 | [no description available] | low | 0 | 0 | nitrile;
quinolines | antineoplastic agent;
tyrosine kinase inhibitor |
| perampanel | [no description available] | low | 0 | 0 | bipyridines;
nitrile;
pyridone | AMPA receptor antagonist;
anticonvulsant |
| tofacitinib | [no description available] | low | 0 | 0 | N-acylpiperidine;
nitrile;
pyrrolopyrimidine;
tertiary amino compound | antirheumatic drug;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide | [no description available] | low | 0 | 0 | 1,3,4-oxadiazoles;
benzamides;
biphenyls;
nitrile | EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| ethaboxam | [no description available] | low | 0 | 0 | 1,3-thiazoles;
aromatic amide;
aromatic amine;
nitrile;
secondary amino compound;
thiophenes | |
| bms 477118 | [no description available] | low | 0 | 0 | adamantanes;
azabicycloalkane;
monocarboxylic acid amide;
nitrile;
tertiary alcohol | EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
hypoglycemic agent |
| alogliptin | [no description available] | low | 0 | 0 | nitrile;
piperidines;
primary amino compound;
pyrimidines | EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
hypoglycemic agent |
| cyflumetofen | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
2-methoxyethyl ester;
beta-ketoester;
nitrile | |
| finafloxacin | [no description available] | low | 0 | 0 | cyclopropanes;
monocarboxylic acid;
nitrile;
organofluorine compound;
quinolone;
secondary amino compound;
tertiary amino compound | antibacterial drug;
antimicrobial agent |
| dactolisib | [no description available] | low | 0 | 0 | imidazoquinoline;
nitrile;
quinolines;
ring assembly;
ureas | antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor |
| mdv 3100 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
benzamides;
imidazolidinone;
monofluorobenzenes;
nitrile;
thiocarbonyl compound | androgen antagonist;
antineoplastic agent |
| trelagliptin | [no description available] | low | 0 | 0 | benzenes;
nitrile | |
| SL-327 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
enamine;
nitrile;
organic sulfide;
primary amino compound;
substituted aniline | EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor;
neuroprotective agent |
| n-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide | [no description available] | low | 0 | 0 | aminopyrimidine;
benzamides;
morpholines;
nitrile;
secondary amino compound;
tertiary amino compound | anti-anaemic agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| incb-018424 | [no description available] | low | 0 | 0 | nitrile;
pyrazoles;
pyrrolopyrimidine | antineoplastic agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| glasdegib | [no description available] | low | 0 | 0 | benzimidazoles;
nitrile;
phenylureas;
piperidines | antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist |
| baricitinib | [no description available] | low | 0 | 0 | azetidines;
nitrile;
pyrazoles;
pyrrolopyrimidine;
sulfonamide | anti-inflammatory agent;
antirheumatic drug;
antiviral agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
immunosuppressive agent |
| GS-441524 | [no description available] | low | 0 | 0 | aromatic amine;
C-nucleoside;
nitrile;
pyrrolotriazine | anticoronaviral agent;
antiviral agent;
drug metabolite |
| alectinib | [no description available] | low | 0 | 0 | aromatic ketone;
morpholines;
nitrile;
organic heterotetracyclic compound;
piperidines | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| delgocitinib | [no description available] | low | 0 | 0 | azaspiro compound;
N-acylazetidine;
nitrile;
pyrrolopyrimidine;
tertiary amino compound;
tertiary carboxamide | anti-inflammatory drug;
antipsoriatic;
antiseborrheic;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| lfm a13 | [no description available] | low | 0 | 0 | aromatic amide;
dibromobenzene;
enamide;
enol;
nitrile;
secondary carboxamide | antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 2.7.11.21 (polo kinase) inhibitor;
geroprotector;
platelet aggregation inhibitor |
| teriflunomide | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic amide;
enamide;
enol;
nitrile;
secondary carboxamide | drug metabolite;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
hepatotoxic agent;
non-steroidal anti-inflammatory drug;
tyrosine kinase inhibitor |
| GS-443902 | [no description available] | low | 0 | 0 | aromatic amine;
C-nucleoside;
nitrile;
organic triphosphate;
pyrrolotriazine | anticoronaviral agent;
antiviral drug;
drug metabolite |
| s 8932 | [no description available] | low | 0 | 0 | aromatic amine;
C-nucleoside;
carboxylic ester;
nitrile;
phosphoramidate ester;
pyrrolotriazine | anticoronaviral agent;
antiviral drug;
prodrug |
| AZ3451 | [no description available] | low | 0 | 0 | benzimidazoles;
benzodioxoles;
nitrile;
organobromine compound;
secondary carboxamide | anti-inflammatory agent;
autophagy inducer;
PAR2 negative allosteric modulator |
| 2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1h-indole-5-carbonitrile | [no description available] | low | 0 | 0 | hydroxyindoles;
morpholines;
nitrile;
pyridines;
tertiary amino compound | antineoplastic agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
tau aggregation inhibitor |
| nirmatrelvir | [no description available] | low | 0 | 0 | azabicyclohexane;
nitrile;
organofluorine compound;
pyrrolidin-2-ones;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide | anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| chloroacetaldehyde | [no description available] | low | 0 | 0 | organochlorine compound | |
| 3-chloroalanine | [no description available] | low | 0 | 0 | chloroalanine;
non-proteinogenic alpha-amino acid;
organochlorine compound | |
| chlordecone | [no description available] | low | 0 | 0 | cyclic ketone;
organochlorine compound | insecticide;
persistent organic pollutant |
| 2-hydroxysaclofen | [no description available] | low | 0 | 0 | organochlorine compound | |
| 3,4-dichloroisocoumarin | [no description available] | low | 0 | 0 | isocoumarins;
organochlorine compound | geroprotector;
serine protease inhibitor |
| 5-(n,n-hexamethylene)amiloride | [no description available] | low | 0 | 0 | aromatic amine;
azepanes;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines | antineoplastic agent;
apoptosis inducer;
odorant receptor antagonist;
sodium channel blocker |
| ethylisopropylamiloride | [no description available] | low | 0 | 0 | aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound | anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker |
| 7-chlorokynurenic acid | [no description available] | low | 0 | 0 | organochlorine compound;
quinolinemonocarboxylic acid | neuroprotective agent;
NMDA receptor antagonist |
| acetochlor | [no description available] | low | 0 | 0 | aromatic amide;
monocarboxylic acid amide;
organochlorine compound | environmental contaminant;
herbicide;
xenobiotic |
| alachlor | [no description available] | low | 0 | 0 | aromatic amide;
monocarboxylic acid amide;
organochlorine compound | environmental contaminant;
herbicide;
xenobiotic |
| alprazolam | [no description available] | low | 0 | 0 | organochlorine compound;
triazolobenzodiazepine | anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic |
| amodiaquine | [no description available] | low | 0 | 0 | aminoquinoline;
organochlorine compound;
phenols;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
drug allergen;
EC 2.1.1.8 (histamine N-methyltransferase) inhibitor;
non-steroidal anti-inflammatory drug;
prodrug |
| benzylhydrochlorothiazide | [no description available] | low | 0 | 0 | benzenes;
benzothiadiazine;
organochlorine compound;
secondary amino compound;
sulfonamide | |
| carmustine | [no description available] | low | 0 | 0 | N-nitrosoureas;
organochlorine compound | alkylating agent;
antineoplastic agent |
| carprofen | [no description available] | low | 0 | 0 | carbazoles;
organochlorine compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug;
photosensitizing agent |
| cgs 15943 | [no description available] | low | 0 | 0 | aromatic amine;
biaryl;
furans;
organochlorine compound;
primary amino compound;
quinazolines;
triazoloquinazoline | adenosine A1 receptor antagonist;
adenosine A2A receptor antagonist;
antineoplastic agent;
central nervous system stimulant |
| chloral hydrate | [no description available] | low | 0 | 0 | aldehyde hydrate;
ethanediol;
organochlorine compound | general anaesthetic;
mouse metabolite;
sedative;
xenobiotic |
| chlorambucil | [no description available] | low | 0 | 0 | aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound | alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent |
| chloroquine | [no description available] | low | 0 | 0 | aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug |
| chloroxine | [no description available] | low | 0 | 0 | monohydroxyquinoline;
organochlorine compound | antibacterial agent;
antifungal drug;
antiseborrheic |
| chlorpromazine | [no description available] | low | 0 | 0 | organochlorine compound;
phenothiazines;
tertiary amine | anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug |
| chlorzoxazone | [no description available] | low | 0 | 0 | 1,3-benzoxazoles;
heteroaryl hydroxy compound;
organochlorine compound | muscle relaxant;
sedative |
| ciprofibrate | [no description available] | low | 0 | 0 | cyclopropanes;
monocarboxylic acid;
organochlorine compound | antilipemic drug |
| clioquinol | [no description available] | low | 0 | 0 | monohydroxyquinoline;
organochlorine compound;
organoiodine compound | antibacterial agent;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
antiprotozoal drug;
chelator;
copper chelator |
| clobazam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
organochlorine compound | anticonvulsant;
anxiolytic drug;
GABA modulator |
| clobenpropit | [no description available] | low | 0 | 0 | imidazoles;
imidothiocarbamic ester;
organochlorine compound | H3-receptor antagonist;
H4-receptor agonist |
| cloxyquin | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| nordazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
organochlorine compound | anticonvulsant;
anxiolytic drug;
GABA modulator;
human metabolite;
sedative |
| diazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
organochlorine compound | anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic |
| diazoxide | [no description available] | low | 0 | 0 | benzothiadiazine;
organochlorine compound;
sulfone | antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent |
| enflurane | [no description available] | low | 0 | 0 | ether;
organochlorine compound;
organofluorine compound | anaesthetic |
| fludiazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
organochlorine compound;
organofluorine compound | anxiolytic drug |
| flurazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
monofluorobenzenes;
organochlorine compound;
tertiary amino compound | anticonvulsant;
anxiolytic drug;
GABAA receptor agonist;
sedative |
| glafenine | [no description available] | low | 0 | 0 | aminoquinoline;
carboxylic ester;
glycol;
organochlorine compound;
secondary amino compound | inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| halothane | [no description available] | low | 0 | 0 | haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound | inhalation anaesthetic |
| hydrochlorothiazide | [no description available] | low | 0 | 0 | benzothiadiazine;
organochlorine compound;
sulfonamide | antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic |
| hydroxychloroquine | [no description available] | low | 0 | 0 | aminoquinoline;
organochlorine compound;
primary alcohol;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
dermatologic drug |
| indapamide | [no description available] | low | 0 | 0 | indoles;
organochlorine compound;
sulfonamide | antihypertensive agent;
diuretic |
| lomustine | [no description available] | low | 0 | 0 | N-nitrosoureas;
organochlorine compound | alkylating agent;
antineoplastic agent |
| loratadine | [no description available] | low | 0 | 0 | benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide | anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist |
| 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one | [no description available] | low | 0 | 0 | chromones;
morpholines;
organochlorine compound | autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector |
| mechlorethamine | [no description available] | low | 0 | 0 | nitrogen mustard;
organochlorine compound | alkylating agent |
| meclofenamic acid | [no description available] | low | 0 | 0 | aminobenzoic acid;
organochlorine compound;
secondary amino compound | analgesic;
anticonvulsant;
antineoplastic agent;
antipyretic;
antirheumatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug |
| methoxyflurane | [no description available] | low | 0 | 0 | ether;
organochlorine compound;
organofluorine compound | hepatotoxic agent;
inhalation anaesthetic;
nephrotoxic agent;
non-narcotic analgesic |
| metolazone | [no description available] | low | 0 | 0 | organochlorine compound;
quinazolines;
sulfonamide | antihypertensive agent;
diuretic;
ion transport inhibitor |
| midazolam | [no description available] | low | 0 | 0 | imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound | anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative |
| mosapramine | [no description available] | low | 0 | 0 | azaspiro compound;
dibenzoazepine;
organochlorine compound;
tertiary amino compound | |
| n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide | [no description available] | low | 0 | 0 | naphthalenes;
organochlorine compound;
primary amino compound;
sulfonamide | |
| oxazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
organochlorine compound | anxiolytic drug;
environmental contaminant;
xenobiotic |
| perphenazine | [no description available] | low | 0 | 0 | N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines | antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug |
| prochlorperazine | [no description available] | low | 0 | 0 | N-alkylpiperazine;
N-methylpiperazine;
organochlorine compound;
phenothiazines | alpha-adrenergic antagonist;
antiemetic;
cholinergic antagonist;
dopamine receptor D2 antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic |
| propachlor | [no description available] | low | 0 | 0 | anilide;
monocarboxylic acid amide;
organochlorine compound | environmental contaminant;
herbicide;
xenobiotic |
| 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol | [no description available] | low | 0 | 0 | benzazepine;
organochlorine compound;
tertiary amino compound | dopaminergic antagonist |
| semustine | [no description available] | low | 0 | 0 | N-nitrosoureas;
organochlorine compound | alkylating agent;
antineoplastic agent;
carcinogenic agent |
| sibutramine | [no description available] | low | 0 | 0 | organochlorine compound;
tertiary amino compound | anti-obesity agent;
serotonin uptake inhibitor |
| tulobuterol | [no description available] | low | 0 | 0 | organochlorine compound | |
| pirinixic acid | [no description available] | low | 0 | 0 | aryl sulfide;
organochlorine compound;
pyrimidines | |
| chloramphenicol | [no description available] | low | 0 | 0 | C-nitro compound;
carboxamide;
diol;
organochlorine compound | antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor |
| chlorquinaldol | [no description available] | low | 0 | 0 | monohydroxyquinoline;
organochlorine compound | antibacterial drug;
antiprotozoal drug;
antiseptic drug |
| 1,1-dichloroethane | [no description available] | low | 0 | 0 | organochlorine compound | |
| trichloroacetaldehyde | [no description available] | low | 0 | 0 | aldehyde;
organochlorine compound | mouse metabolite |
| trichloroacetic acid | [no description available] | low | 0 | 0 | monocarboxylic acid;
organochlorine compound | carcinogenic agent;
metabolite;
mouse metabolite |
| chloropicrin | [no description available] | low | 0 | 0 | C-nitro compound;
one-carbon compound;
organochlorine compound | antifungal agrochemical;
fumigant insecticide;
nematicide |
| chloropentafluoroethane | [no description available] | low | 0 | 0 | organochlorine compound;
organofluorine compound | |
| dichloroacetaldehyde | [no description available] | low | 0 | 0 | organochlorine compound | |
| dichloroacetic acid | [no description available] | low | 0 | 0 | monocarboxylic acid;
organochlorine compound | astringent;
marine metabolite |
| sulfachlorpyridazine | [no description available] | low | 0 | 0 | organochlorine compound;
pyridazines;
sulfonamide | antibacterial drug;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor |
| thiopropazate | [no description available] | low | 0 | 0 | acetate ester;
N-alkylpiperazine;
organochlorine compound;
phenothiazines | dopaminergic antagonist;
phenothiazine antipsychotic drug |
| hexachlorobutadiene | [no description available] | low | 0 | 0 | organochlorine compound | |
| symclosene | [no description available] | low | 0 | 0 | 1,3,5-triazinanes;
organochlorine compound | |
| 3,3'-dichlorobenzidine | [no description available] | low | 0 | 0 | biphenyls;
monochlorobenzenes;
organochlorine compound | |
| 1,2-dibromo-3-chloropropane | [no description available] | low | 0 | 0 | organochlorine compound | |
| 1,2,3-trichloropropane | [no description available] | low | 0 | 0 | organochlorine compound | |
| 1,3-dichloro-2-propanol | [no description available] | low | 0 | 0 | organochlorine compound;
secondary alcohol | cross-linking reagent;
protic solvent |
| benzotrichloride | [no description available] | low | 0 | 0 | benzenes;
organochlorine compound;
volatile organic compound | carcinogenic agent |
| epichlorohydrin | [no description available] | low | 0 | 0 | epoxide;
organochlorine compound | |
| 1-bromo-2-chloroethane | [no description available] | low | 0 | 0 | haloalkane;
organobromine compound;
organochlorine compound | mutagen |
| allyl chloride | [no description available] | low | 0 | 0 | organochlorine compound | |
| cyanuric chloride | [no description available] | low | 0 | 0 | chloro-1,3,5-triazine;
organochlorine compound | cross-linking reagent |
| chlorendic acid | [no description available] | low | 0 | 0 | bridged compound;
dicarboxylic acid;
organochlorine compound | carcinogenic agent |
| tris(chloroethyl)phosphate | [no description available] | low | 0 | 0 | organochlorine compound;
trialkyl phosphate | |
| chloranil | [no description available] | low | 0 | 0 | 1,4-benzoquinones;
organochlorine compound | EC 2.7.1.33 (pantothenate kinase) inhibitor;
metabolite |
| folpet | [no description available] | low | 0 | 0 | organochlorine compound;
organosulfur compound;
phthalimide fungicide | antifungal agrochemical |
| trichloronate | [no description available] | low | 0 | 0 | organochlorine compound | |
| bromochlorodifluoromethane | [no description available] | low | 0 | 0 | one-carbon compound;
organobromine compound;
organochlorine compound;
organofluorine compound | |
| metofenazate | [no description available] | low | 0 | 0 | N-alkylpiperazine;
organochlorine compound;
phenothiazines | |
| mustard gas | [no description available] | low | 0 | 0 | ethyl sulfide;
organochlorine compound | alkylating agent;
carcinogenic agent;
vesicant |
| 1-chloro-2-methylpropene | [no description available] | low | 0 | 0 | organochlorine compound | |
| 8-chlorotheophylline | [no description available] | low | 0 | 0 | organochlorine compound;
purines | central nervous system stimulant |
| 1,3-dichloroacetone | [no description available] | low | 0 | 0 | ketone;
organochlorine compound | |
| bis(chloromethyl) ether | [no description available] | low | 0 | 0 | ether;
organochlorine compound | alkylating agent;
carcinogenic agent |
| trichloroacetonitrile | [no description available] | low | 0 | 0 | aliphatic nitrile;
organochlorine compound | |
| 3-chloro-2-methylprop-1-ene | [no description available] | low | 0 | 0 | organochlorine compound | |
| 2,6-dichlorobenzoquinone | [no description available] | low | 0 | 0 | 1,4-benzoquinones;
organochlorine compound | carcinogenic agent;
poison |
| n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide | [no description available] | low | 0 | 0 | organochlorine compound;
organofluorine compound;
phenylsulfamide fungicide;
sulfamides | antifungal agrochemical;
genotoxin |
| lormetazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
organochlorine compound | sedative |
| 2-chloro-1,4-naphthoquinone | [no description available] | low | 0 | 0 | 1,4-naphthoquinones;
organochlorine compound | |
| chlordecone alcohol | [no description available] | low | 0 | 0 | organochlorine compound | |
| dichlofluanid | [no description available] | low | 0 | 0 | organochlorine compound;
organofluorine compound;
phenylsulfamide fungicide;
sulfamides | acaricide;
antifungal agrochemical |
| win 18446 | [no description available] | low | 0 | 0 | organochlorine compound;
secondary carboxamide | EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor |
| pyrazon | [no description available] | low | 0 | 0 | benzenes;
organochlorine compound;
primary amino compound;
pyridazinone | environmental contaminant;
herbicide;
xenobiotic |
| bromocyclen | [no description available] | low | 0 | 0 | organochlorine compound | |
| 5-chlorouracil | [no description available] | low | 0 | 0 | organochlorine compound | |
| amiloride | [no description available] | low | 0 | 0 | aromatic amine;
guanidines;
organochlorine compound;
pyrazines | diuretic;
sodium channel blocker |
| dienochlor | [no description available] | low | 0 | 0 | organochlorine compound | |
| captafol | [no description available] | low | 0 | 0 | isoindoles;
organochlorine compound;
organosulfur compound;
phthalimide fungicide | antifungal agrochemical |
| o-chlorobenzylidenemalonitrile | [no description available] | low | 0 | 0 | organochlorine compound | |
| diloxanide furoate | [no description available] | low | 0 | 0 | carboxylic ester;
furans;
organochlorine compound;
tertiary carboxamide | antiamoebic agent;
prodrug |
| cladribine | [no description available] | low | 0 | 0 | organochlorine compound;
purine 2'-deoxyribonucleoside | antineoplastic agent;
immunosuppressive agent |
| dichloroacetylene | [no description available] | low | 0 | 0 | organochlorine compound | |
| chloroethylene oxide | [no description available] | low | 0 | 0 | organochlorine compound | |
| 4-chloro-7-nitrobenzofurazan | [no description available] | low | 0 | 0 | benzoxadiazole;
C-nitro compound;
organochlorine compound | EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor;
fluorescent probe;
fluorochrome |
| clodronic acid | [no description available] | low | 0 | 0 | 1,1-bis(phosphonic acid);
one-carbon compound;
organochlorine compound | antineoplastic agent;
bone density conservation agent |
| ornidazole | [no description available] | low | 0 | 0 | C-nitro compound;
imidazoles;
organochlorine compound;
secondary alcohol | antiamoebic agent;
antibacterial drug;
antiinfective agent;
antiprotozoal drug;
antitrichomonal drug;
epitope |
| didesethylflurazepam | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
monofluorobenzenes;
organochlorine compound;
primary amino compound | anticonvulsant;
anxiolytic drug;
drug metabolite;
GABAA receptor agonist;
sedative |
| clonixin | [no description available] | low | 0 | 0 | aminopyridine;
organochlorine compound;
pyridinemonocarboxylic acid | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
platelet aggregation inhibitor;
vasodilator agent |
| chlorodibromomethane | [no description available] | low | 0 | 0 | organochlorine compound | |
| 1-chloro-2-propanol | [no description available] | low | 0 | 0 | organochlorine compound;
secondary alcohol | |
| pyoluteorin | [no description available] | low | 0 | 0 | aromatic ketone;
beta-hydroxy ketone;
diol;
organochlorine compound;
organochlorine pesticide;
polyketide;
pyrroles;
resorcinols | antibacterial agent;
antifungal agent;
apoptosis inducer;
bacterial metabolite;
marine metabolite |
| 5-chloro-2-methyl-4-isothiazolin-3-one | [no description available] | low | 0 | 0 | 1,2-thiazoles;
organochlorine compound | antimicrobial agent;
environmental contaminant;
xenobiotic |
| triforine | [no description available] | low | 0 | 0 | amide fungicide;
formamides;
N-alkylpiperazine;
organochlorine compound | allergen;
antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| octachlorostyrene | [no description available] | low | 0 | 0 | organochlorine compound | |
| perfosfamide | [no description available] | low | 0 | 0 | nitrogen mustard;
organochlorine compound;
peroxol;
phosphorodiamide | alkylating agent;
antineoplastic agent;
drug allergen;
immunosuppressive agent;
metabolite |
| nimustine | [no description available] | low | 0 | 0 | aminopyrimidine;
N-nitrosoureas;
organochlorine compound | alkylating agent;
antineoplastic agent |
| tiamenidine | [no description available] | low | 0 | 0 | organochlorine compound | |
| metazachlor | [no description available] | low | 0 | 0 | aromatic amide;
organochlorine compound;
pyrazoles | environmental contaminant;
herbicide;
xenobiotic |
| cicletanine | [no description available] | low | 0 | 0 | organochlorine compound | |
| lonapalene | [no description available] | low | 0 | 0 | naphthalenes;
organochlorine compound | |
| sertindole | [no description available] | low | 0 | 0 | heteroarylpiperidine;
imidazolidinone;
organochlorine compound;
organofluorine compound;
phenylindole | alpha-adrenergic antagonist;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic antagonist |
| ziprasidone | [no description available] | low | 0 | 0 | 1,2-benzisothiazole;
indolones;
organochlorine compound;
piperazines | antipsychotic agent;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
psychotropic drug;
serotonergic antagonist |
| tiludronic acid | [no description available] | low | 0 | 0 | organochlorine compound | |
| r 29148 | [no description available] | low | 0 | 0 | organochlorine compound;
oxazolidines;
tertiary carboxamide | herbicide safener |
| efavirenz | [no description available] | low | 0 | 0 | acetylenic compound;
benzoxazine;
cyclopropanes;
organochlorine compound;
organofluorine compound | antiviral drug;
HIV-1 reverse transcriptase inhibitor |
| ro 5-3335 | [no description available] | low | 0 | 0 | 1,4-benzodiazepinone;
organochlorine compound;
pyrroles | anti-HIV-1 agent;
antineoplastic agent;
HIV-1 Tat inhibitor;
RUNX1 inhibitor |
| 5-bromo-4-chloro-3-indolyl beta-galactoside | [no description available] | low | 0 | 0 | beta-D-galactoside;
D-aldohexose derivative;
indolyl carbohydrate;
organobromine compound;
organochlorine compound | chromogenic compound |
| 5-bromo-4-chloro-3-indoxyl phosphate | [no description available] | low | 0 | 0 | aryl phosphate;
indoles;
organobromine compound;
organochlorine compound | chromogenic compound |
| z 424 | [no description available] | low | 0 | 0 | organochlorine compound | |
| tianeptine | [no description available] | low | 0 | 0 | dibenzothiazepine;
monocarboxylic acid;
organochlorine compound | |
| trichlorosucrose | [no description available] | low | 0 | 0 | disaccharide derivative;
organochlorine compound | environmental contaminant;
sweetening agent;
xenobiotic |
| clobuzarit | [no description available] | low | 0 | 0 | biphenyls;
organochlorine compound | |
| eberconazole | [no description available] | low | 0 | 0 | dibenzannulene;
imidazoles;
organochlorine compound | |
| gr 117289 | [no description available] | low | 0 | 0 | 1-benzofurans;
biaryl;
imidazolyl carboxylic acid;
monocarboxylic acid;
organobromine compound;
organochlorine compound;
tetrazoles | angiotensin receptor antagonist;
antihypertensive agent |
| rebeccamycin | [no description available] | low | 0 | 0 | indolocarbazole;
N-glycosyl compound;
organic heterohexacyclic compound;
organochlorine compound | |
| 4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole | [no description available] | low | 0 | 0 | organochlorine compound | |
| 8-((4-chlorophenyl)thio)cyclic-3',5'-amp | [no description available] | low | 0 | 0 | 3',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
aryl sulfide;
organochlorine compound | protein kinase agonist |
| 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid | [no description available] | low | 0 | 0 | organochlorine compound | |
| kathon 930 | [no description available] | low | 0 | 0 | 1,2-thiazoles;
organochlorine compound | environmental contaminant;
fungicide;
xenobiotic |
| dimethenamid | [no description available] | low | 0 | 0 | aromatic amide;
ether;
organochlorine compound;
thiophenes | |
| fluxofenim | [no description available] | low | 0 | 0 | organochlorine compound | |
| 3-chlorolactate | [no description available] | low | 0 | 0 | 2-hydroxy monocarboxylic acid;
organochlorine compound | |
| 2,6-dichloroisonicotinic acid | [no description available] | low | 0 | 0 | monocarboxylic acid;
organochlorine compound;
pyridines | EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor |
| 4-hydroxycyclophosphamide | [no description available] | low | 0 | 0 | nitrogen mustard;
organochlorine compound;
phosphorodiamide | alkylating agent;
metabolite |
| fotemustine | [no description available] | low | 0 | 0 | N-nitrosoureas;
organic phosphonate;
organochlorine compound | |
| 1-hydroxymethylmidazolam | [no description available] | low | 0 | 0 | aromatic primary alcohol;
imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound | drug metabolite;
human blood serum metabolite;
human urinary metabolite |
| s-chloromethylglutathione | [no description available] | low | 0 | 0 | organochlorine compound;
S-substituted glutathione | alkylating agent;
bacterial xenobiotic metabolite;
mouse metabolite |
| exp3174 | [no description available] | low | 0 | 0 | biphenylyltetrazole;
imidazoles;
organochlorine compound | metabolite |
| florfenicol | [no description available] | low | 0 | 0 | organochlorine compound;
organofluorine compound;
secondary alcohol;
secondary carboxamide;
sulfone | antimicrobial agent |
| monochlorobimane | [no description available] | low | 0 | 0 | organochlorine compound;
pyrazolopyrazole | fluorochrome |
| Prothioconazole-desthio | [no description available] | low | 0 | 0 | organochlorine compound | |
| saclofen | [no description available] | low | 0 | 0 | organochlorine compound | |
| piperaquine | [no description available] | low | 0 | 0 | aminoquinoline;
N-arylpiperazine;
organochlorine compound | antimalarial |
| mk 0663 | [no description available] | low | 0 | 0 | bipyridines;
organochlorine compound;
sulfone | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug |
| norketamine | [no description available] | low | 0 | 0 | organochlorine compound | |
| 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline | [no description available] | low | 0 | 0 | isoquinolines;
organochlorine compound | |
| 4-hydroxymidazolam | [no description available] | low | 0 | 0 | imidazobenzodiazepine;
monofluorobenzenes;
organic hydroxy compound;
organochlorine compound | drug metabolite;
human blood serum metabolite;
human urinary metabolite |
| cki 7 | [no description available] | low | 0 | 0 | isoquinolines;
organochlorine compound;
primary amino compound;
sulfonamide | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| 6-bromo-3-(bromomethyl)-7-methyl-2,3,7-trichloro-1-octene | [no description available] | low | 0 | 0 | monoterpenoid;
organobromine compound;
organochlorine compound | algal metabolite;
antineoplastic agent;
marine metabolite |
| pyrrolomycin a | [no description available] | low | 0 | 0 | antibiotic antifungal agent;
C-nitro compound;
organochlorine compound;
pyrroles | antibacterial agent;
bacterial metabolite |
| sk&f 83959 | [no description available] | low | 0 | 0 | benzazepine;
catechols;
organochlorine compound;
tertiary amino compound | dopamine agonist |
| 1-hydroxymethylmidazolam glucuronide | [no description available] | low | 0 | 0 | beta-D-glucosiduronic acid;
imidazobenzodiazepine;
monofluorobenzenes;
monosaccharide derivative;
organochlorine compound | drug metabolite;
human blood serum metabolite;
human urinary metabolite |
| cox 189 | [no description available] | low | 0 | 0 | amino acid;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
secondary amino compound | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug |
| 5,6-dehydronorketamine | [no description available] | low | 0 | 0 | organochlorine compound | |
| 6-chloro-3,5-diaminopyrazine-3-carboxamide | [no description available] | low | 0 | 0 | organochlorine compound;
pyrazines | |
| chloroorienticin b | [no description available] | low | 0 | 0 | cyclic ether;
glycopeptide;
heterodetic cyclic peptide;
monosaccharide derivative;
organochlorine compound;
polyphenol | antimicrobial agent;
bacterial metabolite |
| lapatinib | [no description available] | low | 0 | 0 | furans;
organochlorine compound;
organofluorine compound;
quinazolines | antineoplastic agent;
tyrosine kinase inhibitor |
| n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide | [no description available] | low | 0 | 0 | chloroindole;
organochlorine compound;
sulfonamide | antineoplastic agent;
EC 4.2.1.1 (carbonic anhydrase) inhibitor |
| nsc-89199 | [no description available] | low | 0 | 0 | carbamate ester;
organochlorine compound;
steroid phosphate | |
| estramustine | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
carbamate ester;
organochlorine compound | alkylating agent;
antineoplastic agent;
radiation protective agent |
| acivicin | [no description available] | low | 0 | 0 | isoxazoles;
non-proteinogenic L-alpha-amino acid;
organochlorine compound | antileishmanial agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor;
glutamine antagonist;
metabolite |
| o-(chloroacetylcarbamoyl)fumagillol | [no description available] | low | 0 | 0 | carbamate ester;
organochlorine compound;
semisynthetic derivative;
sesquiterpenoid;
spiro-epoxide | angiogenesis inhibitor;
antineoplastic agent;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
methionine aminopeptidase 2 inhibitor;
retinoic acid receptor alpha antagonist |
| griseofulvin | [no description available] | low | 0 | 0 | 1-benzofurans;
antibiotic antifungal drug;
benzofuran antifungal drug;
organochlorine compound;
oxaspiro compound | antibacterial agent;
Penicillium metabolite |
| mometasone furoate | [no description available] | low | 0 | 0 | 11beta-hydroxy steroid;
2-furoate ester;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
organochlorine compound;
steroid ester | anti-allergic agent;
anti-inflammatory drug |
| ochratoxin a | [no description available] | low | 0 | 0 | isochromanes;
monocarboxylic acid amide;
N-acyl-L-phenylalanine;
organochlorine compound;
phenylalanine derivative | Aspergillus metabolite;
calcium channel blocker;
carcinogenic agent;
mycotoxin;
nephrotoxin;
Penicillium metabolite;
teratogenic agent |
| chlorpromazine n-oxide | [no description available] | low | 0 | 0 | organochlorine compound;
phenothiazines;
tertiary amine oxide | metabolite |
| loteprednol etabonate | [no description available] | low | 0 | 0 | 11beta-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
etabonate ester;
organochlorine compound;
steroid acid ester;
steroid ester | anti-inflammatory drug |
| melphalan | [no description available] | low | 0 | 0 | L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound | alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent |
| bromochloroacetic acid | [no description available] | low | 0 | 0 | 2-bromocarboxylic acid;
monocarboxylic acid;
organochlorine compound | |
| tolfenamic acid | [no description available] | low | 0 | 0 | aminobenzoic acid;
organochlorine compound;
secondary amino compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| 1,4-dichloro-2-butene | [no description available] | low | 0 | 0 | organochlorine compound | |
| 1-(4-chlorophenyl)-1-cyclohexyl-3-(4-morpholinyl)-1-propanol | [no description available] | low | 0 | 0 | organochlorine compound | |
| 2-[(3-chlorophenyl)-(3-oxo-5-propyl-1,2-dihydropyrazol-4-yl)methyl]propanedinitrile | [no description available] | low | 0 | 0 | organochlorine compound | |
| 1-piperidinecarboxylic acid (5-chloro-8-quinolinyl) ester | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| tram 34 | [no description available] | low | 0 | 0 | organochlorine compound | |
| N-(2-chlorophenyl)hydrazine-1-carbothioamide | [no description available] | low | 0 | 0 | organochlorine compound | |
| 3-pyridinecarboxylic acid (5-chloro-8-quinolinyl) ester | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| CHIC-35 | [no description available] | low | 0 | 0 | aromatic compound;
organic heterotricyclic compound;
organochlorine compound;
primary carboxamide | EC 3.5.1.98 (histone deacetylase) inhibitor |
| 3-(2-chlorophenyl)-5-methyl-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-isoxazolecarboxamide | [no description available] | low | 0 | 0 | organochlorine compound | |
| 4-chloro-N-(4-chloro-2-methylphenyl)-5-dithiazolimine | [no description available] | low | 0 | 0 | organochlorine compound | |
| 1-[(7-chloro-4-quinolinyl)amino]-3-(2,4-dichlorophenyl)thiourea | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| 2-chloro-N-[3-[(2-chlorophenyl)methyl]-2-thiazolylidene]acetamide | [no description available] | low | 0 | 0 | organochlorine compound | |
| 2-(4-chlorophenyl)guanidine | [no description available] | low | 0 | 0 | organochlorine compound | |
| 2-(4-chlorophenyl)-6-(methylthio)-4-oxo-2,3-dihydro-1,3-thiazine-5-carbonitrile | [no description available] | low | 0 | 0 | organochlorine compound | |
| N-(4-chlorophenethyl)-N'-(4-chlorophenyl)urea | [no description available] | low | 0 | 0 | organochlorine compound | |
| 6-amino-4-(3-chlorophenyl)-3-methyl-1-(phenylmethyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | organochlorine compound;
pyranopyrazole | |
| 5-chloro-7-[3-pyridinyl-(2-pyridinylamino)methyl]-8-quinolinol | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| cb 7969312 | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| dasatinib | [no description available] | low | 0 | 0 | 1,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor |
| N-[(4-chlorophenyl)methyl]-3-(1-ethyl-5-methyl-4-pyrazolyl)-4,5-dihydroisoxazole-5-carboxamide | [no description available] | low | 0 | 0 | organochlorine compound | |
| 4-butyl-3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | organochlorine compound | |
| 5-chloro-7-[1-piperidinyl(2-pyridinyl)methyl]-8-quinolinol | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| 5-chloro-7-[(4-ethyl-1-piperazinyl)-(3-pyridinyl)methyl]-8-quinolinol | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| ML162 | [no description available] | low | 0 | 0 | monochlorobenzenes;
monomethoxybenzene;
organochlorine compound;
secondary carboxamide;
tertiary carboxamide;
thiophenes | EC 1.11.1.9 (glutathione peroxidase) inhibitor;
ferroptosis inducer |
| epi 001 | [no description available] | low | 0 | 0 | diether;
organochlorine compound | androgen antagonist |
| 3-[(3-chlorophenyl)methylthio]-N-cyclopentylpropanamide | [no description available] | low | 0 | 0 | organochlorine compound | |
| 5-[3-(2-chloro-6-methoxy-3-quinolinyl)-5-(2-furanyl)-3,4-dihydropyrazol-2-yl]-5-oxopentanoic acid | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| [3-(2-chloro-6-ethoxy-3-quinolinyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-thiophen-2-ylmethanone | [no description available] | low | 0 | 0 | organochlorine compound;
quinolines | |
| 4-chloro-N-(1,3,4-thiadiazol-2-yl)-5-dithiazolimine | [no description available] | low | 0 | 0 | organochlorine compound | |
| [4-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-(2-oxiranyl)methanone | [no description available] | low | 0 | 0 | organochlorine compound | |
| clodronic acid | [no description available] | low | 0 | 0 | organochlorine compound | |
| ex 527 | [no description available] | low | 0 | 0 | carbazoles;
monocarboxylic acid amide;
organochlorine compound | |
| ro 60-0175 | [no description available] | low | 0 | 0 | indoles;
organochlorine compound;
organofluorine compound;
primary amino compound | |
| maytansine | [no description available] | low | 0 | 0 | alpha-amino acid ester;
carbamate ester;
epoxide;
maytansinoid;
organic heterotetracyclic compound;
organochlorine compound | antimicrobial agent;
antimitotic;
antineoplastic agent;
plant metabolite;
tubulin modulator |
| arachidonyl-2-chloroethylamide | [no description available] | low | 0 | 0 | fatty amide;
organochlorine compound;
secondary carboxamide;
synthetic cannabinoid | CB1 receptor agonist;
CB2 receptor agonist;
neuroprotective agent |
| nostocarboline | [no description available] | low | 0 | 0 | alkaloid;
beta-carbolines;
organic cation;
organochlorine compound | antimalarial;
EC 3.1.1.8 (cholinesterase) inhibitor;
metabolite |
| su 11652 | [no description available] | low | 0 | 0 | olefinic compound;
organochlorine compound;
oxindoles;
pyrrolecarboxamide;
tertiary amino compound | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor |
| chlorferron | [no description available] | low | 0 | 0 | organochlorine compound | |
| 2-amino-6-chloropurine | [no description available] | low | 0 | 0 | 2-aminopurines;
organochlorine compound | |
| salubrinal | [no description available] | low | 0 | 0 | aminal;
organochlorine compound;
quinolines;
secondary carboxamide;
thioureas | |
| picloxydine | [no description available] | low | 0 | 0 | organochlorine compound | |
| ma-1 | [no description available] | low | 0 | 0 | carboxamidine;
organochlorine compound;
pyrimidone;
pyrrolidines | antineoplastic agent;
EC 2.4.2.4 (thymidine phosphorylase) inhibitor |
| chaetoviridin a | [no description available] | low | 0 | 0 | azaphilone;
beta-hydroxy ketone;
enone;
gamma-lactone;
organic heterotricyclic compound;
organochlorine compound;
secondary alcohol | antifungal agent;
Chaetomium metabolite |
| su 5614 | [no description available] | low | 0 | 0 | organochlorine compound;
oxindoles;
pyrroles | vascular endothelial growth factor receptor antagonist |
| bay 12-9566 | [no description available] | low | 0 | 0 | biphenyls;
organochlorine compound | |
| rwj-333369 | [no description available] | low | 0 | 0 | organochlorine compound | |
| 2-[3-(3-chlorophenyl)-5-isoxazolyl]-1-hydroxy-4H-1,2,4-benzotriazin-3-one | [no description available] | low | 0 | 0 | organochlorine compound | |
| lonafarnib | [no description available] | low | 0 | 0 | benzocycloheptapyridine;
heteroarylpiperidine;
N-acylpiperidine;
organobromine compound;
organochlorine compound;
ureas | |
| cangrelor | [no description available] | low | 0 | 0 | adenosine 5'-phosphate;
aryl sulfide;
nucleoside triphosphate analogue;
organochlorine compound;
organofluorine compound;
secondary amino compound | P2Y12 receptor antagonist;
platelet aggregation inhibitor |
| avanafil | [no description available] | low | 0 | 0 | aromatic amide;
monocarboxylic acid amide;
organochlorine compound;
prolinols;
pyrimidines | EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent |
| rivaroxaban | [no description available] | low | 0 | 0 | aromatic amide;
lactam;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
oxazolidinone;
thiophenes | anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor |
| estin | [no description available] | low | 0 | 0 | 1-benzofurans;
ether;
methyl ester;
organochlorine compound;
oxaspiro compound;
phenols | Aspergillus metabolite;
Penicillium metabolite |
| pitolisant | [no description available] | low | 0 | 0 | organochlorine compound | |
| dysidenin | [no description available] | low | 0 | 0 | 1,3-thiazoles;
organochlorine compound;
secondary carboxamide;
tertiary carboxamide | animal metabolite;
marine metabolite;
toxin |
| 6-chlorotryptophan | [no description available] | low | 0 | 0 | L-alpha-amino acid zwitterion;
L-tryptophan derivative;
non-proteinogenic L-alpha-amino acid;
organochlorine compound | |
| marizomib | [no description available] | low | 0 | 0 | beta-lactone;
gamma-lactam;
organic heterobicyclic compound;
organochlorine compound;
salinosporamide | antineoplastic agent;
proteasome inhibitor |
| lorcaserin | [no description available] | low | 0 | 0 | benzazepine;
organochlorine compound | anti-obesity agent;
appetite depressant |
| 3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide | [no description available] | low | 0 | 0 | organochlorine compound | |
| N-[(2-chlorophenyl)methyl]-2-(4-ethyl-1-oxo-2-pyrrolo[1,2-d][1,2,4]triazinyl)acetamide | [no description available] | low | 0 | 0 | organochlorine compound | |
| complestatin | [no description available] | low | 0 | 0 | cyclic ether;
heterodetic cyclic peptide;
indoles;
organic heterobicyclic compound;
organochlorine compound;
peptide antibiotic;
polyphenol | anti-HIV-1 agent;
antimicrobial agent;
HIV-1 integrase inhibitor;
metabolite |
| neuroprotectin a | [no description available] | low | 0 | 0 | cyclic ether;
heterodetic cyclic peptide;
indoles;
organochlorine compound;
polyphenol | HIV-1 integrase inhibitor;
metabolite |
| 4'-epichaetoviridin A | [no description available] | low | 0 | 0 | azaphilone;
beta-hydroxy ketone;
enone;
gamma-lactone;
organic heterotricyclic compound;
organochlorine compound;
secondary alcohol | Chaetomium metabolite |
| plx 4720 | [no description available] | low | 0 | 0 | aromatic ketone;
difluorobenzene;
organochlorine compound;
pyrrolopyridine;
sulfonamide | antineoplastic agent;
B-Raf inhibitor |
| N-[3-(3-chlorophenyl)phenyl]-1-(3-isoxazolylmethyl)-4-piperidinecarboxamide | [no description available] | low | 0 | 0 | biphenyls;
organochlorine compound | |
| N-[3-(3-chlorophenyl)phenyl]-1-(3-oxolanylmethyl)-4-piperidinecarboxamide | [no description available] | low | 0 | 0 | biphenyls;
organochlorine compound | |
| marinopyrrole a | [no description available] | low | 0 | 0 | aromatic ketone;
organochlorine compound;
phenols;
pyrroles | antibacterial agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
marine metabolite |
| suvorexant | [no description available] | low | 0 | 0 | 1,3-benzoxazoles;
aromatic amide;
diazepine;
organochlorine compound;
triazoles | central nervous system depressant;
orexin receptor antagonist |
| chaetoviridin E | [no description available] | low | 0 | 0 | azaphilone;
enone;
gamma-lactone;
organic heterotricyclic compound;
organochlorine compound | Chaetomium metabolite |
| pexidartinib | [no description available] | low | 0 | 0 | aminopyridine;
organochlorine compound;
organofluorine compound;
pyrrolopyridine;
secondary amino compound | antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| 4-chloro-N-(5-methyl-1,3,4-oxadiazol-2-yl)-5-dithiazolimine | [no description available] | low | 0 | 0 | organochlorine compound | |
| thiopental sodium | [no description available] | low | 0 | 0 | organochlorine compound;
piperazines;
pyrimidines | antineoplastic agent;
tyrosine kinase inhibitor |
| jq1 compound | [no description available] | low | 0 | 0 | carboxylic ester;
organochlorine compound;
tert-butyl ester;
thienotriazolodiazepine | angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
bromodomain-containing protein 4 inhibitor;
cardioprotective agent;
ferroptosis inducer |
| N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide;
bridged compound;
olefinic compound;
organochlorine compound;
organofluorine compound;
pyrazoles | |
| lornoxicam | [no description available] | low | 0 | 0 | heteroaryl hydroxy compound;
monocarboxylic acid amide;
organochlorine compound;
pyridines;
thienothiazine | antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| AZD3463 | [no description available] | low | 0 | 0 | aminopiperidine;
aminopyrimidine;
indoles;
monomethoxybenzene;
organochlorine compound;
secondary amino compound;
tertiary amino compound | antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| opt 80 | [no description available] | low | 0 | 0 | carboxylic ester;
glycoside;
macrolide antibiotic;
organochlorine compound;
phenols | antibacterial drug;
bacterial metabolite;
EC 2.7.7.6 (RNA polymerase) inhibitor |
| acarbose | [no description available] | low | 0 | 0 | chondramide;
indoles;
organochlorine compound;
phenols | antineoplastic agent;
bacterial metabolite |
| clothianidin | [no description available] | low | 0 | 0 | 1,3-thiazoles;
2-nitroguanidine derivative;
clothianidin;
organochlorine compound | environmental contaminant;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic |
| THZ531 | [no description available] | low | 0 | 0 | aminopyrimidine;
enamide;
indoles;
N-acylpiperidine;
organochlorine compound;
secondary amino compound;
secondary carboxamide | antineoplastic agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor |
| clozapine | [no description available] | low | 0 | 0 | benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound | adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic |
| norclozapine | [no description available] | low | 0 | 0 | dibenzodiazepine;
organochlorine compound;
piperazines | delta-opioid receptor agonist;
metabolite;
serotonergic antagonist |
| 5-[1-[(2-chlorophenyl)methyl]-2,5-dimethyl-3-pyrrolyl]-N-(1-methoxypropan-2-yl)-6H-1,3,4-thiadiazin-2-amine | [no description available] | low | 0 | 0 | organochlorine compound | |
| 8-((4-chlorophenyl)thio)cyclic-3',5'-gmp | [no description available] | low | 0 | 0 | 3',5'-cyclic purine nucleotide;
aryl sulfide;
organochlorine compound;
ribonucleotide | protein kinase agonist |
| XL413 | [no description available] | low | 0 | 0 | benzofuropyrimidine;
organochlorine compound;
pyrrolidines | antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| celecoxib | [no description available] | low | 0 | 0 | organofluorine compound;
pyrazoles;
sulfonamide;
toluenes | cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| cgs 12066 | [no description available] | low | 0 | 0 | N-arylpiperazine;
organofluorine compound;
pyrroloquinoxaline | serotonergic agonist |
| diflunisal | [no description available] | low | 0 | 0 | monohydroxybenzoic acid;
organofluorine compound | non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| droperidol | [no description available] | low | 0 | 0 | aromatic ketone;
benzimidazoles;
organofluorine compound | anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic |
| flucytosine | [no description available] | low | 0 | 0 | aminopyrimidine;
nucleoside analogue;
organofluorine compound;
pyrimidine antifungal drug;
pyrimidone | prodrug |
| flufenamic acid | [no description available] | low | 0 | 0 | aromatic amino acid;
organofluorine compound | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| fluphenazine | [no description available] | low | 0 | 0 | N-alkylpiperazine;
organofluorine compound;
phenothiazines | anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug |
| flumazenil | [no description available] | low | 0 | 0 | ethyl ester;
imidazobenzodiazepine;
organofluorine compound | antidote to benzodiazepine poisoning;
GABA antagonist |
| flumequine | [no description available] | low | 0 | 0 | 3-oxo monocarboxylic acid;
organofluorine compound;
pyridoquinoline;
quinolone antibiotic | |
| fluorouracil | [no description available] | low | 0 | 0 | nucleobase analogue;
organofluorine compound | antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic |
| fluphenazine depot | [no description available] | low | 0 | 0 | decanoate ester;
N-alkylpiperazine;
organofluorine compound;
phenothiazines | dopaminergic antagonist;
phenothiazine antipsychotic drug;
prodrug |
| vanoxerine | [no description available] | low | 0 | 0 | ether;
N-alkylpiperazine;
organofluorine compound;
tertiary amino compound | dopamine uptake inhibitor |
| haloperidol | [no description available] | low | 0 | 0 | aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol | antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist |
| isoflurane | [no description available] | low | 0 | 0 | organofluorine compound | inhalation anaesthetic |
| ketanserin | [no description available] | low | 0 | 0 | aromatic ketone;
organofluorine compound;
piperidines;
quinazolines | alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist |
| mefloquine hydrochloride | [no description available] | low | 0 | 0 | organofluorine compound;
piperidines;
quinolines;
secondary alcohol | |
| ofloxacin | [no description available] | low | 0 | 0 | 3-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline | |
| pipamperone | [no description available] | low | 0 | 0 | aromatic ketone;
bipiperidines;
monocarboxylic acid amide;
organofluorine compound;
tertiary amino compound | dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist |
| risperidone | [no description available] | low | 0 | 0 | 1,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine | alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist |
| ritanserin | [no description available] | low | 0 | 0 | organofluorine compound;
piperidines;
thiazolopyrimidine | antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist |
| sb 220025 | [no description available] | low | 0 | 0 | aminopyrimidine;
imidazoles;
organofluorine compound;
piperidines | angiogenesis inhibitor;
anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| sb 202190 | [no description available] | low | 0 | 0 | imidazoles;
organofluorine compound;
phenols;
pyridines | apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| sevoflurane | [no description available] | low | 0 | 0 | ether;
organofluorine compound | central nervous system depressant;
inhalation anaesthetic;
platelet aggregation inhibitor |
| fluoroacetic acid | [no description available] | low | 0 | 0 | haloacetic acid;
organofluorine compound | EC 4.2.1.3 (aconitate hydratase) inhibitor |
| spiperone | [no description available] | low | 0 | 0 | aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound | alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist |
| gatifloxacin | [no description available] | low | 0 | 0 | N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone | antiinfective agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor |
| tosufloxacin | [no description available] | low | 0 | 0 | 1,8-naphthyridine derivative;
amino acid;
aminopyrrolidine;
monocarboxylic acid;
organofluorine compound;
primary amino compound;
quinolone antibiotic;
tertiary amino compound | |
| trifluoperazine | [no description available] | low | 0 | 0 | N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines | antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug |
| triflupromazine | [no description available] | low | 0 | 0 | organofluorine compound;
phenothiazines;
tertiary amine | anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic |
| zardaverine | [no description available] | low | 0 | 0 | organofluorine compound;
pyridazinone | anti-asthmatic drug;
bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
peripheral nervous system drug |
| floxuridine | [no description available] | low | 0 | 0 | nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside | antimetabolite;
antineoplastic agent;
antiviral drug;
radiosensitizing agent |
| trifluridine | [no description available] | low | 0 | 0 | nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside | antimetabolite;
antineoplastic agent;
antiviral drug;
EC 2.1.1.45 (thymidylate synthase) inhibitor |
| 1,1-difluoroethylene | [no description available] | low | 0 | 0 | olefinic compound;
organofluorine compound | |
| 1,1,1-trifluoro-2-chloroethane | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2-fluoroadenosine | [no description available] | low | 0 | 0 | adenosines;
organofluorine compound | |
| perfluorotributylamine | [no description available] | low | 0 | 0 | organofluorine compound | blood substitute;
greenhouse gas;
solvent |
| 5-fluorouridine | [no description available] | low | 0 | 0 | organofluorine compound;
uridines | mutagen |
| 5-fluorotryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
organofluorine compound;
tryptophan derivative | |
| difluoroacetic acid | [no description available] | low | 0 | 0 | monocarboxylic acid;
organofluorine compound | |
| fluroxene | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2,3,4,5,6-pentafluorobenzyl alcohol | [no description available] | low | 0 | 0 | benzyl alcohols;
organofluorine compound | |
| 2-fluoroadenine | [no description available] | low | 0 | 0 | organofluorine compound;
purines | antineoplastic agent |
| hexafluoroisopropanol | [no description available] | low | 0 | 0 | organofluorine compound;
secondary alcohol | drug metabolite |
| pimozide | [no description available] | low | 0 | 0 | benzimidazoles;
heteroarylpiperidine;
organofluorine compound | antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist |
| 5-fluorocytidine | [no description available] | low | 0 | 0 | cytidines;
organofluorine compound | |
| doxifluridine | [no description available] | low | 0 | 0 | organofluorine compound;
pyrimidine 5'-deoxyribonucleoside | antimetabolite;
antineoplastic agent;
prodrug |
| fludarabine phosphate | [no description available] | low | 0 | 0 | nucleoside analogue;
organofluorine compound;
purine arabinonucleoside monophosphate | antimetabolite;
antineoplastic agent;
antiviral agent;
DNA synthesis inhibitor;
immunosuppressive agent;
prodrug |
| flubendazole | [no description available] | low | 0 | 0 | aromatic ketone;
benzimidazoles;
carbamate ester;
organofluorine compound | antinematodal drug;
teratogenic agent |
| flunixin | [no description available] | low | 0 | 0 | aminopyridine;
organofluorine compound;
pyridinemonocarboxylic acid | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| desflurane | [no description available] | low | 0 | 0 | organofluorine compound | inhalation anaesthetic |
| temafloxacin | [no description available] | low | 0 | 0 | amino acid;
monocarboxylic acid;
N-arylpiperazine;
organofluorine compound;
quinolone antibiotic;
quinolone;
secondary amino compound;
tertiary amino compound | |
| gemcitabine hydrochloride | [no description available] | low | 0 | 0 | hydrochloride;
organofluorine compound | anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral drug;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
immunosuppressive agent;
radiosensitizing agent |
| gemcitabine | [no description available] | low | 0 | 0 | organofluorine compound;
pyrimidine 2'-deoxyribonucleoside | antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic |
| emtricitabine | [no description available] | low | 0 | 0 | monothioacetal;
nucleoside analogue;
organofluorine compound;
pyrimidone | antiviral drug;
HIV-1 reverse transcriptase inhibitor |
| capecitabine | [no description available] | low | 0 | 0 | carbamate ester;
cytidines;
organofluorine compound | antimetabolite;
antineoplastic agent;
prodrug |
| 4-fluorofentanyl | [no description available] | low | 0 | 0 | monocarboxylic acid amide;
organofluorine compound;
piperidines | |
| heptafluorobutyric anhydride | [no description available] | low | 0 | 0 | acyclic carboxylic anhydride;
organofluorine compound | chromatographic reagent |
| perfluorotripropylamine | [no description available] | low | 0 | 0 | organofluorine compound | blood substitute |
| 3-fluoropyruvate | [no description available] | low | 0 | 0 | 2-oxo monocarboxylic acid;
organofluorine compound | |
| flunoxaprofen | [no description available] | low | 0 | 0 | 1,3-benzoxazoles;
monocarboxylic acid;
organofluorine compound | antirheumatic drug;
hepatotoxic agent;
non-steroidal anti-inflammatory drug;
protein kinase C agonist |
| halopropane | [no description available] | low | 0 | 0 | organofluorine compound | |
| enrofloxacin | [no description available] | low | 0 | 0 | cyclopropanes;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone | antibacterial agent;
antimicrobial agent;
antineoplastic agent |
| flurithromycin | [no description available] | low | 0 | 0 | cyclic ketone;
erythromycin derivative;
organofluorine compound;
semisynthetic derivative | antibacterial drug |
| nebivolol | [no description available] | low | 0 | 0 | chromanes;
diol;
organofluorine compound;
secondary alcohol;
secondary amino compound | |
| nucleocidin | [no description available] | low | 0 | 0 | 6-aminopurines;
adenosines;
diol;
organofluorine compound;
sulfamate ester | antibacterial agent;
bacterial metabolite;
nucleoside antibiotic;
protein synthesis inhibitor;
trypanocidal drug |
| fluoroacetaldehyde | [no description available] | low | 0 | 0 | aldehyde;
organofluorine compound | cardiotoxic agent |
| fc 75 | [no description available] | low | 0 | 0 | alkyltetrahydrofuran;
organofluorine compound | |
| hei 712 | [no description available] | low | 0 | 0 | organofluorine compound;
quinolone | |
| fluquinconazole | [no description available] | low | 0 | 0 | conazole fungicide;
dichlorobenzene;
organofluorine compound;
quinazolines;
triazole fungicide;
triazoles | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| dithiopyr | [no description available] | low | 0 | 0 | organofluorine compound;
pyridines;
thioester | |
| fulvestrant | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid;
3-hydroxy steroid;
organofluorine compound;
sulfoxide | antineoplastic agent;
estrogen antagonist;
estrogen receptor antagonist |
| fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether | [no description available] | low | 0 | 0 | organofluorine compound | |
| paliperidone | [no description available] | low | 0 | 0 | 1,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine;
secondary alcohol | |
| sc 58125 | [no description available] | low | 0 | 0 | organofluorine compound;
pyrazoles;
sulfone | antineoplastic agent;
cyclooxygenase 2 inhibitor |
| clofarabine | [no description available] | low | 0 | 0 | adenosines;
organofluorine compound | antimetabolite;
antineoplastic agent |
| 5-fluoromethylornithine | [no description available] | low | 0 | 0 | organofluorine compound;
ornithine derivative | EC 2.6.1.13 (ornithine aminotransferase) inhibitor |
| nitroflurbiprofen | [no description available] | low | 0 | 0 | biphenyls;
carboxylic ester;
nitrate ester;
organofluorine compound | cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
geroprotector;
non-steroidal anti-inflammatory drug;
vasodilator agent |
| ezogabine | [no description available] | low | 0 | 0 | carbamate ester;
organofluorine compound;
secondary amino compound;
substituted aniline | anticonvulsant;
potassium channel modulator |
| 5-fluorowillardiine | [no description available] | low | 0 | 0 | L-alanine derivative;
non-proteinogenic L-alpha-amino acid;
organofluorine compound | AMPA receptor agonist |
| perfluoro-n-methyldecahydroisoquinoline | [no description available] | low | 0 | 0 | organofluorine compound | blood substitute |
| fc 80 | [no description available] | low | 0 | 0 | alkyltetrahydrofuran;
organofluorine compound | |
| ezetimibe | [no description available] | low | 0 | 0 | azetidines;
beta-lactam;
organofluorine compound | anticholesteremic drug;
antilipemic drug;
antimetabolite |
| 5-fluorouridine 5'-phosphate | [no description available] | low | 0 | 0 | organofluorine compound;
pyrimidine ribonucleoside 5'-monophosphate | drug metabolite |
| canertinib | [no description available] | low | 0 | 0 | monochlorobenzenes;
morpholines;
organofluorine compound;
quinazolines | antineoplastic agent;
tyrosine kinase inhibitor |
| jte 522 | [no description available] | low | 0 | 0 | 1,3-oxazoles;
organofluorine compound;
sulfonamide | cyclooxygenase 2 inhibitor |
| trifluoromethionine | [no description available] | low | 0 | 0 | L-methionine derivative;
non-proteinogenic L-alpha-amino acid;
organofluorine compound | |
| diflomotecan | [no description available] | low | 0 | 0 | epsilon-lactone;
organic heteropentacyclic compound;
organofluorine compound;
organonitrogen heterocyclic compound;
tertiary alcohol | antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor |
| 5',5',5'-trifluoroleucine | [no description available] | low | 0 | 0 | leucine derivative;
non-proteinogenic alpha-amino acid;
organofluorine compound | |
| sorbinil | [no description available] | low | 0 | 0 | azaspiro compound;
chromanes;
imidazolidinone;
organofluorine compound;
oxaspiro compound | antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor |
| linezolid | [no description available] | low | 0 | 0 | acetamides;
morpholines;
organofluorine compound;
oxazolidinone | antibacterial drug;
protein synthesis inhibitor |
| 2'-deoxy-2-fluoroadenosine | [no description available] | low | 0 | 0 | adenosines;
organofluorine compound | |
| 8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pent-4-yn-1-yl-9H-purin-6-amine | [no description available] | low | 0 | 0 | 6-aminopurines;
acetylenic compound;
methoxybenzenes;
monochlorobenzenes;
organofluorine compound | antineoplastic agent;
Hsp90 inhibitor |
| efinaconazole | [no description available] | low | 0 | 0 | conazole antifungal drug;
olefinic compound;
organofluorine compound;
piperidines;
tertiary alcohol;
tertiary amino compound;
triazole antifungal drug | EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| favipiravir | [no description available] | low | 0 | 0 | hydroxypyrazine;
organofluorine compound;
primary carboxamide | anticoronaviral agent;
antiviral drug;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor |
| ck-0944666 | [no description available] | low | 0 | 0 | benzamides;
indoles;
organofluorine compound | actin polymerisation inhibitor |
| 2-(3-Chloro-2-fluorophenyl)-2,3-dihydroisothiazol-3-one | [no description available] | low | 0 | 0 | organofluorine compound | |
| 4-[(3-fluorophenyl)methyl-(3-pyridinylmethyl)amino]-4-oxobutanoic acid | [no description available] | low | 0 | 0 | organofluorine compound | |
| 4-(4-fluorophenyl)-3H-thiazole-2-thione | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2-(4-chlorophenyl)-5-(4-fluorophenyl)-1,3,4-oxadiazole | [no description available] | low | 0 | 0 | organofluorine compound | |
| N-[(4-fluorophenyl)methyl]-2-thiophen-2-ylacetamide | [no description available] | low | 0 | 0 | organofluorine compound | |
| 1-(cycloheptylideneamino)-3-(4-fluorophenyl)thiourea | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2-(2-fluorophenyl)-5-phenyl-4-thieno[2,3-d][1,3]oxazinone | [no description available] | low | 0 | 0 | organofluorine compound | |
| sulindac | [no description available] | low | 0 | 0 | monocarboxylic acid;
organofluorine compound;
sulfoxide | analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent |
| N-cyano-N'-(2-fluorophenyl)carbamimidothioic acid [2-(tert-butylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | organofluorine compound | |
| N-(4-fluorobenzyl)urea | [no description available] | low | 0 | 0 | organofluorine compound | |
| N1-(3-chloro-4-fluorophenyl)-2-(methylthio)acetamide | [no description available] | low | 0 | 0 | organofluorine compound | |
| ethyl 1-[4-(4-chlorobenzenesulfonamido)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate | [no description available] | low | 0 | 0 | ethyl ester;
monochlorobenzenes;
organofluorine compound;
pyrazoles;
sulfonamide | |
| S-[5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl] 5-(phenylethynyl)furan-2-carbothioate | [no description available] | low | 0 | 0 | acetylenic compound;
furans;
organofluorine compound;
thioester;
triazoles | |
| 4-[1-(4-fluorophenyl)ethyl]-3-thiophen-2-yl-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | organofluorine compound | |
| 1-(4-fluorophenyl)-1-cyclopentanecarboxylic acid [2-(2,6-dimethyl-4-morpholinyl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | organofluorine compound | |
| deracoxib | [no description available] | low | 0 | 0 | organofluorine compound;
pyrazoles;
sulfonamide | cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| 6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline | [no description available] | low | 0 | 0 | organic heterotricyclic compound;
organofluorine compound;
pyridines;
secondary amino compound | |
| 1-(4-fluorophenyl)-N-methyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carbothioamide | [no description available] | low | 0 | 0 | organofluorine compound | |
| 2-[[2-[3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]thio]acetic acid butyl ester | [no description available] | low | 0 | 0 | organofluorine compound | |
| 1-[(2-fluorophenyl)methyl]-4-pyrazolamine | [no description available] | low | 0 | 0 | organofluorine compound | |
| 3-[2,2-dichloro-1-(3-fluoro-4-methylphenyl)ethyl]-1,1-bis(phenylmethyl)urea | [no description available] | low | 0 | 0 | organofluorine compound | |
| arachidonyltrifluoromethane | [no description available] | low | 0 | 0 | fatty acid derivative;
ketone;
olefinic compound;
organofluorine compound | EC 3.1.1.4 (phospholipase A2) inhibitor |
| sulindac sulfide | [no description available] | low | 0 | 0 | aryl sulfide;
monocarboxylic acid;
organofluorine compound | antineoplastic agent;
apoptosis inducer;
non-steroidal anti-inflammatory drug |
| (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | [no description available] | low | 0 | 0 | dihydroxy monocarboxylic acid;
indoles;
organofluorine compound | |
| sulindac sulfone | [no description available] | low | 0 | 0 | monocarboxylic acid;
organofluorine compound;
sulfone | apoptosis inducer;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor |
| 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz(h)imidazo(4,5-f)isoquinoline-7-one | [no description available] | low | 0 | 0 | organic heterotetracyclic compound;
organofluorine compound | EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| z-val-ala-asp(ome)-fluoromethylketone | [no description available] | low | 0 | 0 | carbamate ester;
organofluorine compound;
tripeptide | apoptosis inhibitor;
protease inhibitor |
| robenacoxib | [no description available] | low | 0 | 0 | aromatic amino acid;
monocarboxylic acid;
organofluorine compound;
phenylacetic acids;
secondary amino compound | cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| netupitant | [no description available] | low | 0 | 0 | aminopyridine;
monocarboxylic acid amide;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound;
toluenes | antiemetic;
neurokinin-1 receptor antagonist |
| flibanserin | [no description available] | low | 0 | 0 | benzimidazoles;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound | antidepressant;
serotonergic agonist;
serotonergic antagonist |
| nepicastat | [no description available] | low | 0 | 0 | 1,3-dihydroimidazole-2-thiones;
organofluorine compound;
primary amino compound;
tetralins | EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor |
| 4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl)benzenesulfonamide | [no description available] | low | 0 | 0 | organofluorine compound;
pyrazoles;
sulfonamide | cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| paliperidone palmitate | [no description available] | low | 0 | 0 | 1,2-benzoxazoles;
fatty acid ester;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine | |
| tafluprost | [no description available] | low | 0 | 0 | isopropyl ester;
organofluorine compound;
prostaglandins Falpha | prostaglandin receptor agonist |
| ticagrelor | [no description available] | low | 0 | 0 | aryl sulfide;
hydroxyether;
organofluorine compound;
secondary amino compound;
triazolopyrimidines | P2Y12 receptor antagonist;
platelet aggregation inhibitor |
| am 694 | [no description available] | low | 0 | 0 | aromatic ketone;
indoles;
organofluorine compound;
organoiodine compound;
synthetic cannabinoid | cannabinoid receptor agonist |
| rucaparib | [no description available] | low | 0 | 0 | azepinoindole;
caprolactams;
organofluorine compound;
secondary amino compound | antineoplastic agent;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor |
| NNC 55-0396 (free base) | [no description available] | low | 0 | 0 | benzimidazoles;
cyclopropanecarboxylate ester;
organofluorine compound;
tertiary amino compound;
tetralins | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
neuroprotective agent;
potassium channel blocker;
T-type calcium channel blocker |
| osu 03012 | [no description available] | low | 0 | 0 | antibiotic antifungal drug;
aromatic amide;
glycine derivative;
organofluorine compound;
phenanthrenes;
pyrazoles | antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor |
| vorapaxar | [no description available] | low | 0 | 0 | carbamate ester;
lactone;
naphthofuran;
organofluorine compound;
pyridines | cardiovascular drug;
platelet aggregation inhibitor;
protease-activated receptor-1 antagonist |
| azd 6244 | [no description available] | low | 0 | 0 | benzimidazoles;
bromobenzenes;
hydroxamic acid ester;
monochlorobenzenes;
organofluorine compound;
secondary amino compound | anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| rolapitant | [no description available] | low | 0 | 0 | azaspiro compound;
ether;
organofluorine compound;
piperidines;
pyrrolidin-2-ones | antiemetic;
neurokinin-1 receptor antagonist |
| r-138727 | [no description available] | low | 0 | 0 | organofluorine compound | |
| fluopicolide | [no description available] | low | 0 | 0 | benzamide fungicide;
benzamides;
dichlorobenzene;
monochloropyridine;
organofluorine compound | antifungal agrochemical |
| gamendazole | [no description available] | low | 0 | 0 | alpha,beta-unsaturated monocarboxylic acid;
dichlorobenzene;
indazoles;
olefinic compound;
organofluorine compound | antispermatogenic agent;
eukaryotic translation elongation factor 1alpha 1 inhibitor;
Hsp90 inhibitor;
synthetic oral contraceptive |
| tedizolid | [no description available] | low | 0 | 0 | carbamate ester;
organofluorine compound;
oxazolidinone;
primary alcohol;
pyridines;
tetrazoles | antimicrobial agent;
drug metabolite;
protein synthesis inhibitor |
| rx-3117 | [no description available] | low | 0 | 0 | organofluorine compound;
primary allylic alcohol;
triol | antimetabolite;
antineoplastic agent;
apoptosis inducer;
DNA synthesis inhibitor;
prodrug |
| bay 63-2521 | [no description available] | low | 0 | 0 | aminopyrimidine;
carbamate ester;
organofluorine compound;
pyrazolopyridine | antihypertensive agent;
soluble guanylate cyclase activator |
| tedizolid phosphate | [no description available] | low | 0 | 0 | carbamate ester;
organofluorine compound;
oxazolidinone;
phosphate monoester;
pyridines;
tetrazoles | antimicrobial agent;
prodrug;
protein synthesis inhibitor |
| tavaborole | [no description available] | low | 0 | 0 | benzoxaborole;
organofluorine compound | antifungal agent;
EC 6.1.1.4 (leucine--tRNA ligase) inhibitor;
protein synthesis inhibitor |
| idelalisib | [no description available] | low | 0 | 0 | aromatic amine;
organofluorine compound;
purines;
quinazolines;
secondary amino compound | antineoplastic agent;
apoptosis inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| zstk474 | [no description available] | low | 0 | 0 | benzimidazoles;
morpholines;
organofluorine compound;
triamino-1,3,5-triazine | antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| trifloxystrobin | [no description available] | low | 0 | 0 | methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
organofluorine compound;
oxime O-ether | antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor |
| 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide;
organofluorine compound;
pyrazoles | |
| n-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide;
cyclopropanes;
organofluorine compound;
pyrazoles;
ring assembly | |
| trametinib | [no description available] | low | 0 | 0 | acetamides;
aromatic amine;
cyclopropanes;
organofluorine compound;
organoiodine compound;
pyridopyrimidine;
ring assembly | anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector |
| butafenacil | [no description available] | low | 0 | 0 | benzoate ester;
diester;
monochlorobenzenes;
olefinic compound;
organofluorine compound | EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| buparlisib | [no description available] | low | 0 | 0 | aminopyridine;
aminopyrimidine;
morpholines;
organofluorine compound | antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| lumacaftor | [no description available] | low | 0 | 0 | aromatic amide;
benzodioxoles;
benzoic acids;
cyclopropanes;
organofluorine compound;
pyridines | CFTR potentiator;
orphan drug |
| ro5126766 | [no description available] | low | 0 | 0 | aryloxypyrimidine;
coumarins;
organofluorine compound;
pyridines;
sulfamides | antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| azd 7545 | [no description available] | low | 0 | 0 | benzamides;
monochlorobenzenes;
organofluorine compound;
secondary carboxamide;
sulfone;
tertiary alcohol;
tertiary carboxamide | EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor;
hypoglycemic agent |
| canagliflozin | [no description available] | low | 0 | 0 | C-glycosyl compound;
organofluorine compound;
thiophenes | hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor |
| navitoclax | [no description available] | low | 0 | 0 | aryl sulfide;
monochlorobenzenes;
morpholines;
N-sulfonylcarboxamide;
organofluorine compound;
piperazines;
secondary amino compound;
sulfone;
tertiary amino compound | antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor |
| dcc-2036 | [no description available] | low | 0 | 0 | organofluorine compound;
phenylureas;
pyrazoles;
pyridinecarboxamide;
quinolines | tyrosine kinase inhibitor |
| TAK-580 | [no description available] | low | 0 | 0 | 1,3-thiazolecarboxamide;
aminopyrimidine;
chloropyridine;
organofluorine compound;
pyrimidinecarboxamide;
secondary carboxamide | antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor |
| dabrafenib | [no description available] | low | 0 | 0 | 1,3-thiazoles;
aminopyrimidine;
organofluorine compound;
sulfonamide | anticoronaviral agent;
antineoplastic agent;
B-Raf inhibitor |
| sofosbuvir | [no description available] | low | 0 | 0 | isopropyl ester;
L-alanyl ester;
nucleotide conjugate;
organofluorine compound;
phosphoramidate ester | antiviral drug;
hepatitis C protease inhibitor;
prodrug |
| [5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid | [no description available] | low | 0 | 0 | organofluorine compound | non-steroidal anti-inflammatory drug |
| torin 1 | [no description available] | low | 0 | 0 | N-acylpiperazine;
N-arylpiperazine;
organofluorine compound;
pyridoquinoline;
quinolines | antineoplastic agent;
mTOR inhibitor |
| ro 4929097 | [no description available] | low | 0 | 0 | dibenzoazepine;
dicarboxylic acid diamide;
lactam;
organofluorine compound | EC 3.4.23.46 (memapsin 2) inhibitor |
| torin 2 | [no description available] | low | 0 | 0 | aminopyridine;
organofluorine compound;
primary amino compound;
pyridoquinoline | antineoplastic agent;
mTOR inhibitor |
| gsk2656157 | [no description available] | low | 0 | 0 | biaryl;
indoles;
methylpyridines;
organofluorine compound;
pyrrolopyrimidine;
tertiary carboxamide | antineoplastic agent;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
PERK inhibitor |
| vericiguat | [no description available] | low | 0 | 0 | aminopyrimidine;
carbamate ester;
organofluorine compound;
pyrazolopyridine | antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent |
| pacific blue succinimidyl ester | [no description available] | low | 0 | 0 | hydroxycoumarin;
N-hydroxysuccinimide ester;
organofluorine compound | fluorochrome |
| 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)propan-2-yl]pyrazole-4-carboxamide | [no description available] | low | 0 | 0 | aromatic amide;
monocarboxylic acid amide;
organofluorine compound;
pyrazoles;
trichlorobenzene | |
| oxathiapiprolin | [no description available] | low | 0 | 0 | 1,3-thiazoles;
isoxazoline;
N-acylpiperidine;
organofluorine compound;
pyrazoles;
tertiary carboxamide | |
| 5-[[5-(4-fluoro-2-hydroxyphenyl)-2-furanyl]methylidene]thiazolidine-2,4-dione | [no description available] | low | 0 | 0 | halophenol;
organofluorine compound | |
| LimKi 3 | [no description available] | low | 0 | 0 | 1,3-thiazoles;
dichlorobenzene;
organofluorine compound;
pyrazoles;
secondary carboxamide | LIM kinase inhibitor |
| ledipasvir | [no description available] | low | 0 | 0 | azaspiro compound;
benzimidazole;
bridged compound;
carbamate ester;
carboxamide;
fluorenes;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organofluorine compound | antiviral drug;
hepatitis C protease inhibitor |
| ivosidenib | [no description available] | low | 0 | 0 | cyanopyridine;
monochlorobenzenes;
organofluorine compound;
pyrrolidin-2-ones;
secondary carboxamide;
tertiary carboxamide | antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor |
| as 1842856 | [no description available] | low | 0 | 0 | organofluorine compound;
primary amino compound;
quinolinemonocarboxylic acid;
quinolone;
secondary amino compound;
tertiary amino compound | anti-obesity agent;
antineoplastic agent;
apoptosis inducer;
autophagy inhibitor;
forkhead box protein O1 inhibitor;
hypoglycemic agent |
| praliciguat | [no description available] | low | 0 | 0 | aminopyrimidine;
isoxazoles;
monofluorobenzenes;
organofluorine compound;
pyrazoles;
secondary amino compound;
tertiary alcohol | anti-inflammatory agent;
antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent |
| enasidenib | [no description available] | low | 0 | 0 | 1,3,5-triazines;
aminopyridine;
aromatic amine;
organofluorine compound;
secondary amino compound;
tertiary alcohol | antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor |
| MMP-9-IN-1 | [no description available] | low | 0 | 0 | aromatic compound;
organic sulfide;
organofluorine compound;
pyrimidone;
secondary carboxamide | antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor |
| 5-(2,5-difluorophenyl)-N-(2-oxolanylmethyl)-6H-1,3,4-thiadiazin-2-amine | [no description available] | low | 0 | 0 | organofluorine compound | |
| cytotrienin a | [no description available] | low | 0 | 0 | cyclopropanecarboxylate ester;
ether;
hydroquinones;
lactam;
macrocycle;
secondary alcohol | antibacterial agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
metabolite |