Page last updated: 2024-08-07 18:44:03
Solute carrier family 22 member 7
A solute carrier family 22 member 7 that is encoded in the genome of rat. [OMA:Q5RLM2, PRO:DNx]
Synonyms
Novel liver transporter;
Organic anion transporter 2
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (16)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| glyburide | Rattus norvegicus (Norway rat) | Ki | 12.3000 | 1 | 0 |
| ketoprofen | Rattus norvegicus (Norway rat) | Ki | 1.8400 | 1 | 0 |
| probenecid | Rattus norvegicus (Norway rat) | IC50 | 977.0000 | 1 | 1 |
| cephaloridine | Rattus norvegicus (Norway rat) | IC50 | 5,000.0000 | 1 | 1 |
| cephalothin | Rattus norvegicus (Norway rat) | IC50 | 1,500.0000 | 1 | 1 |
| cefoperazone | Rattus norvegicus (Norway rat) | IC50 | 1,620.0000 | 1 | 1 |
| pravastatin | Rattus norvegicus (Norway rat) | IC50 | 449.0000 | 1 | 1 |
| cefamandole | Rattus norvegicus (Norway rat) | IC50 | 3,180.0000 | 1 | 1 |
| cefotaxime | Rattus norvegicus (Norway rat) | IC50 | 5,000.0000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| alpha-ketoglutaric acid | Rattus norvegicus (Norway rat) | Km | 17.8000 | 1 | 1 |
| salicylic acid | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 1 |
| indomethacin | Rattus norvegicus (Norway rat) | Km | 0.3660 | 1 | 0 |
| zalcitabine | Rattus norvegicus (Norway rat) | Km | 3,000.0000 | 1 | 0 |
| zidovudine | Rattus norvegicus (Norway rat) | Km | 26.0000 | 1 | 0 |
| dinoprostone | Rattus norvegicus (Norway rat) | Km | 38.5000 | 1 | 0 |
| dinoprost | Rattus norvegicus (Norway rat) | Km | 0.4140 | 1 | 1 |