Page last updated: 2024-08-07 16:24:17
Neuromedin-K receptor
A protein that is a translation product of the TACR3 gene in guinea pig. [PRO:DNx, UniProtKB:P30098]
Synonyms
NKR;
NK-3 receptor;
NK-3R;
Neurokinin B receptor;
Tachykinin receptor 3
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (6)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| cp 96345 | Cavia porcellus (domestic guinea pig) | IC50 | 10.0000 | 1 | 1 |
| senktide | Cavia porcellus (domestic guinea pig) | IC50 | 0.0120 | 1 | 1 |
| sr 142806 | Cavia porcellus (domestic guinea pig) | Ki | 0.0007 | 2 | 2 |
| neurokinin b | Cavia porcellus (domestic guinea pig) | IC50 | 0.0020 | 1 | 1 |
| sb 223412 | Cavia porcellus (domestic guinea pig) | Ki | 0.0044 | 2 | 2 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| propranolol | Cavia porcellus (domestic guinea pig) | Kd | 0.0024 | 1 | 1 |
| sr 142806 | Cavia porcellus (domestic guinea pig) | Kd | 0.0011 | 3 | 3 |
| sb 223412 | Cavia porcellus (domestic guinea pig) | Kd | 0.0139 | 2 | 2 |