Assay ID | Title | Year | Journal | Article |
AID146414 | Inhibition concentration against Neuronal nitric oxide synthase (nNOS) at 10 uM concentration | 2004 | Journal of medicinal chemistry, Feb-12, Volume: 47, Issue:4
| 5-Fluorinated L-lysine analogues as selective induced nitric oxide synthase inhibitors. |
AID92005 | Inhibitory activity against human inducible nitric oxide synthase | 1996 | Journal of medicinal chemistry, Feb-02, Volume: 39, Issue:3
| 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. |
AID92009 | In vitro inhibition of human Inducible nitric oxide synthase. | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
AID67995 | Compound was evaluated for the Inhibition of endothelial isoform of Endothelial nitric oxide synthase (eNOS)enzyme | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Acetamidine lysine derivative, N-(5(S)-amino-6,7-dihydroxyheptyl)ethanimidamide dihydrochloride: a highly selective inhibitor of human inducible nitric oxide synthase. |
AID243012 | Ratio between Endothelial nitric oxide synthase and Inducible nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Sep-06, Volume: 14, Issue:17
| Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase. |
AID147247 | The compound was tested for competitive antagonist of Nitric oxide synthase | 2000 | Bioorganic & medicinal chemistry letters, May-15, Volume: 10, Issue:10
| Examination of N-hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation. |
AID243005 | Ratio between Neuronal nitric oxide synthase and Inducible nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Sep-06, Volume: 14, Issue:17
| Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase. |
AID146115 | Inhibitory activity against human neuronal nitric oxide synthase | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo. |
AID92304 | Inhibition concentration against Inducible nitric oxide synthase (iNOS) at 10 uM concentration | 2004 | Journal of medicinal chemistry, Feb-12, Volume: 47, Issue:4
| 5-Fluorinated L-lysine analogues as selective induced nitric oxide synthase inhibitors. |
AID1063490 | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 5 uM after 24 hrs by Griess assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Synthesis of tricyclic fused coumarin sulfonates and their inhibitory effects on LPS-induced nitric oxide and PGE2 productions in RAW 264.7 macrophages. |
AID240945 | Inhibitory activity against Neuronal nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Sep-06, Volume: 14, Issue:17
| Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase. |
AID240996 | Inhibitory activity against Inducible nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Sep-06, Volume: 14, Issue:17
| Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase. |
AID234295 | Selectivity is the ratio of IC50 of mouse inducible NOS and Rat brain constitutive NOS | 1994 | Journal of medicinal chemistry, Nov-11, Volume: 37, Issue:23
| L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. |
AID181503 | Inhibition of conversion of [3H]L-Arg to [3H]L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellum | 2001 | Bioorganic & medicinal chemistry letters, Apr-23, Volume: 11, Issue:8
| 3,4-Dihydro-1-isoquinolinamines: a novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency. |
AID427901 | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as NO production at 10 uM treated 1 hr before LPS challenge measured after 24 hrs by Griess reagent assay (RVb= 28.72 +/- 1.31 uM) | 2009 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 19, Issue:15
| Phenolic glycosides from Alangium salviifolium leaves with inhibitory activity on LPS-induced NO, PGE(2), and TNF-alpha production. |
AID356479 | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess method | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9
| Saponins from Cussonia bancoensis and their inhibitory effects on nitric oxide production. |
AID68164 | Selectivity for endothelial nitric oxide synthase over inducible nitric oxide synthase | 2004 | Journal of medicinal chemistry, Feb-12, Volume: 47, Issue:4
| 5-Fluorinated L-lysine analogues as selective induced nitric oxide synthase inhibitors. |
AID1650939 | Antiinflammatory activity against murine RAW264.7 cells assessed as inhibition of LPS-induced NO production at 40 uM preincubated for 1 hr followed by LPS stimulation and measured after 24 hrs by Griess assay relative to control | 2020 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 30, Issue:4
| Inhibitory effects of triarylpyrazole derivatives on LPS-induced nitric oxide and PGE |
AID513346 | Inhibition of wild-type Bacillus subtilis 168 1A1 lysine riboswitch 179 lysc assessed as reduction of beta-galactosidase activity at 5 mM after 3 hrs by lacZ reporter gene assay | 2007 | Nature chemical biology, Jan, Volume: 3, Issue:1
| Antibacterial lysine analogs that target lysine riboswitches. |
AID241124 | Inhibitory concentration against Neuronal nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23
| Synthesis of analogs of (1,4)-3- and 5-imino oxazepane, thiazepane, and diazepane as inhibitors of nitric oxide synthases. |
AID146416 | Selectivity for Neuronal nitric oxide synthase over inducible nitric oxide synthase | 2004 | Journal of medicinal chemistry, Feb-12, Volume: 47, Issue:4
| 5-Fluorinated L-lysine analogues as selective induced nitric oxide synthase inhibitors. |
AID68135 | Inhibitory activity against human endothelial nitric oxide synthase | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo. |
AID1688220 | Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced NO level at 40 uM incubated for 1 hr followed by LPS stimulation and measured after 24 hrs by Griess reagent based assay | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents. |
AID1564031 | Anti-inflammatory activity in mouse RAW264.7 cells assessed as remaining LPS-induced NO production at 40 uM preincubated for 1 hr followed by LPS addition and measured after 24 hrs by Griess reagent-based assay relative to control | 2019 | European journal of medicinal chemistry, Oct-15, Volume: 180 | Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators. |
AID234272 | Selectivity is defined as the ratio of the IC50(hncNOS) to IC50(hiNOS) | 1996 | Journal of medicinal chemistry, Feb-02, Volume: 39, Issue:3
| 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. |
AID235902 | Selectivity index determined by the ratio of IC50 of eNOS to the iNOS | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Acetamidine lysine derivative, N-(5(S)-amino-6,7-dihydroxyheptyl)ethanimidamide dihydrochloride: a highly selective inhibitor of human inducible nitric oxide synthase. |
AID607321 | Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. |
AID182968 | Inhibition of LPS induced nitrite production in rat following 4 hr of oral administration | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo. |
AID356480 | Cytotoxicity against LPS-stimulated mouse RAW264.7 cells by Griess method | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9
| Saponins from Cussonia bancoensis and their inhibitory effects on nitric oxide production. |
AID1537347 | Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation and measured after 24 hrs by Griess reagent based colorimetric method | 2019 | Journal of natural products, 02-22, Volume: 82, Issue:2
| Chloraserrtone A, a Sesquiterpenoid Dimer from Chloranthus serratus. |
AID513344 | Antibacterial activity against Bacillus subtilis 168 1A1 at 100 uM after 24 hrs by by CLSI method | 2007 | Nature chemical biology, Jan, Volume: 3, Issue:1
| Antibacterial lysine analogs that target lysine riboswitches. |
AID1367568 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs by Griess assay | 2017 | Bioorganic & medicinal chemistry letters, 12-01, Volume: 27, Issue:23
| Inhibitory effect of moschamine isolated from Carthamus tinctorius on LPS-induced inflammatory mediators via AP-1 and STAT1/3 inactivation in RAW 264.7 macrophages. |
AID234085 | Selectivity for inhibition of neuronal nitric oxide synthases to that of inhibition of inducible nitric oxide synthases | 2000 | Bioorganic & medicinal chemistry letters, Sep-04, Volume: 10, Issue:17
| Substituted 2-aminopyridines as inhibitors of nitric oxide synthases. |
AID53933 | Inhibitory concentration against nitric oxide synthesis in intact DLD-1 cells | 2001 | Bioorganic & medicinal chemistry letters, Apr-23, Volume: 11, Issue:8
| 3,4-Dihydro-1-isoquinolinamines: a novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency. |
AID235903 | Selectivity index determined by the ratio of IC50 of nNOS to the iNOS | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Acetamidine lysine derivative, N-(5(S)-amino-6,7-dihydroxyheptyl)ethanimidamide dihydrochloride: a highly selective inhibitor of human inducible nitric oxide synthase. |
AID1329427 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 24 hrs by Griess assay | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9
| Chlojaponilactone B from Chloranthus japonicus: Suppression of Inflammatory Responses via Inhibition of the NF-κB Signaling Pathway. |
AID1063492 | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Synthesis of tricyclic fused coumarin sulfonates and their inhibitory effects on LPS-induced nitric oxide and PGE2 productions in RAW 264.7 macrophages. |
AID68141 | In vitro inhibition of human endothelial nitric oxide synthase. | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
AID244220 | Ratio of inhibitory concentration against Endothelial nitric oxide synthase to Neuronal nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23
| Synthesis of analogs of (1,4)-3- and 5-imino oxazepane, thiazepane, and diazepane as inhibitors of nitric oxide synthases. |
AID1063489 | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 20 uM after 24 hrs by Griess assay | 2014 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
| Synthesis of tricyclic fused coumarin sulfonates and their inhibitory effects on LPS-induced nitric oxide and PGE2 productions in RAW 264.7 macrophages. |
AID1192870 | Antiinflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced NO production after 24 hrs by Griess assay | 2015 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 25, Issue:5
| Constituents of the stem barks of Ailanthus altissima and their potential to inhibit LPS-induced nitric oxide production. |
AID146117 | Inhibitory activity against human Neuronal nitric oxide synthase | 1996 | Journal of medicinal chemistry, Feb-02, Volume: 39, Issue:3
| 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. |
AID513343 | Binding affinity to Bacillus subtilis 168 1A1 lysine riboswitch 179 lysc by in-line probing assay | 2007 | Nature chemical biology, Jan, Volume: 3, Issue:1
| Antibacterial lysine analogs that target lysine riboswitches. |
AID92004 | Inhibitory activity of compound against human inducible nitric oxide synthase | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo. |
AID68136 | Inhibitory activity against human Endothelial nitric oxide synthase | 1996 | Journal of medicinal chemistry, Feb-02, Volume: 39, Issue:3
| 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. |
AID1355607 | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay | 2018 | Journal of natural products, 07-27, Volume: 81, Issue:7
| Chemical Constituents of Apios americana Tubers and Their Inhibitory Activities on Nitric Oxide Production in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. |
AID91992 | Compound was evaluated for the Inhibition of induced isoform of Inducible nitric oxide synthase | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Acetamidine lysine derivative, N-(5(S)-amino-6,7-dihydroxyheptyl)ethanimidamide dihydrochloride: a highly selective inhibitor of human inducible nitric oxide synthase. |
AID146120 | In vitro inhibition of human neuronal nitric oxide synthase. | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
AID68131 | Inhibitory activity against endothelial nitric oxide synthase (eNOS) | 2000 | Bioorganic & medicinal chemistry letters, Sep-04, Volume: 10, Issue:17
| Substituted 2-aminopyridines as inhibitors of nitric oxide synthases. |
AID234271 | Selectivity is defined as the ratio of the IC50(hecNOS) to IC50(hiNOS) | 1996 | Journal of medicinal chemistry, Feb-02, Volume: 39, Issue:3
| 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms. |
AID92167 | Tested for inhibition of mouse inducible nitric oxide synthase | 1994 | Journal of medicinal chemistry, Nov-11, Volume: 37, Issue:23
| L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. |
AID85322 | Ability to inhibit conversion of [3H]L-Arg to [3H]L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cells | 2001 | Bioorganic & medicinal chemistry letters, Apr-23, Volume: 11, Issue:8
| 3,4-Dihydro-1-isoquinolinamines: a novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency. |
AID146109 | Inhibitory activity against neuronal nitric oxide synthase | 2000 | Bioorganic & medicinal chemistry letters, Sep-04, Volume: 10, Issue:17
| Substituted 2-aminopyridines as inhibitors of nitric oxide synthases. |
AID316792 | Inhibition of human iNOS expressed in human DLD1 cells after 1 hr | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
AID53921 | Ability to inhibit conversion of [3H]L-Arg to [3H]L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cells | 2001 | Bioorganic & medicinal chemistry letters, Apr-23, Volume: 11, Issue:8
| 3,4-Dihydro-1-isoquinolinamines: a novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency. |
AID92181 | Tested for inhibition of rat brain inducible nitric oxide synthase | 1994 | Journal of medicinal chemistry, Nov-11, Volume: 37, Issue:23
| L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. |
AID1355117 | Inhibition of LPS-stimulated nitric oxide production in rat RAW264.7 cells after 24 hrs by Griess assay | 2018 | Journal of natural products, 06-22, Volume: 81, Issue:6
| Iridoids from the Roots of Patrinia scabra and Their Inhibitory Potential on LPS-Induced Nitric Oxide Production. |
AID68162 | Inhibition concentration against Endothelial nitric oxide synthase (eNOS) at 10 uM concentration | 2004 | Journal of medicinal chemistry, Feb-12, Volume: 47, Issue:4
| 5-Fluorinated L-lysine analogues as selective induced nitric oxide synthase inhibitors. |
AID53793 | Inhibitory activity against synthesis of inducible nitric oxide synthase by DLD-1 cells | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo. |
AID241153 | Inhibitory concentration against Inducible nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23
| Synthesis of analogs of (1,4)-3- and 5-imino oxazepane, thiazepane, and diazepane as inhibitors of nitric oxide synthases. |
AID92001 | Inhibitory activity against inducible nitric oxide synthase (iNOS) | 2000 | Bioorganic & medicinal chemistry letters, Sep-04, Volume: 10, Issue:17
| Substituted 2-aminopyridines as inhibitors of nitric oxide synthases. |
AID241071 | Inhibitory activity against Endothelial nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Sep-06, Volume: 14, Issue:17
| Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase. |
AID316796 | Selectivity for human nNOS to human iNOS | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
AID1537348 | Cytotoxicity against mouse RAW264.7 cells assessed as cellular metabolic activity at 50 uM after 48 hrs by MTT assay relative to control | 2019 | Journal of natural products, 02-22, Volume: 82, Issue:2
| Chloraserrtone A, a Sesquiterpenoid Dimer from Chloranthus serratus. |
AID316797 | Inhibition of cytokine-induced iNOS activity in human DLD1 cells after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
AID241215 | Inhibitory concentration against Endothelial nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23
| Synthesis of analogs of (1,4)-3- and 5-imino oxazepane, thiazepane, and diazepane as inhibitors of nitric oxide synthases. |
AID316794 | Inhibition of human nNOS expressed in insect SF9 cells after 1 hr | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
AID147245 | Pseudo-first order inactivation rate constant against nitric oxide synthase was determined | 2000 | Bioorganic & medicinal chemistry letters, May-15, Volume: 10, Issue:10
| Examination of N-hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation. |
AID316795 | Selectivity for human eNOS to human iNOS | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
AID513357 | Antibacterial activity against Bacillus subtilis 168 1A1 after 24 hrs by CLSI method | 2007 | Nature chemical biology, Jan, Volume: 3, Issue:1
| Antibacterial lysine analogs that target lysine riboswitches. |
AID244221 | Ratio of inhibitory concentration against Endothelial nitric oxide synthase to Inducible nitric oxide synthase | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23
| Synthesis of analogs of (1,4)-3- and 5-imino oxazepane, thiazepane, and diazepane as inhibitors of nitric oxide synthases. |
AID146105 | Compound was evaluated for the Inhibition of Neuronal nitric oxide synthase | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Acetamidine lysine derivative, N-(5(S)-amino-6,7-dihydroxyheptyl)ethanimidamide dihydrochloride: a highly selective inhibitor of human inducible nitric oxide synthase. |
AID316793 | Inhibition of human eNOS expressed in insect SF9 cells after 1 hr | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
AID234083 | Selectivity for inhibition of inducible nitric oxide synthases to that of inhibition of endothelial cell nitric oxide synthases | 2000 | Bioorganic & medicinal chemistry letters, Sep-04, Volume: 10, Issue:17
| Substituted 2-aminopyridines as inhibitors of nitric oxide synthases. |
AID607320 | Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. |
AID607322 | Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. |
AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |